LRP6 mutation in a family with early coronary disease and metabolic risk factors

Science

Volumn 315, Issue 5816, 2007, Pages 1278-1282

  Mani, Arya ^a   Radhakrishnan, Jayaram ^a   Wang, He ^a   Mani, Alaleh ^b   Mani, Mohammad Ali ^c   Nelson Williams, Carol ^a   Carew, Khary S ^a   Mane, Shrikant ^a   Najmabadi, Hossein ^d   Wu, Dan ^a   Lifton, Richard P ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b AMIRKABIR UNIVERSITY OF TECHNOLOGY   (Iran)

^c ISLAMIC AZAD UNIVERSITY   (Iran)

^d UNIVERSITY OF SOCIAL WELFARE AND REHABILITATION SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CYSTEINE; EPIDERMAL GROWTH FACTOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; WNT PROTEIN;

CARDIOVASCULAR DISEASE; CAUSE OF DEATH; METABOLISM; MUTATION; RISK FACTOR;

AMINO ACID SUBSTITUTION; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CARDIOVASCULAR RISK; CAUSE OF DEATH; CHROMOSOME 12P; CORONARY ARTERY DISEASE; DIABETES MELLITUS; EARLY DIAGNOSIS; FEMALE; GENE; GENE MUTATION; GENETIC DISORDER; GENETIC LINKAGE; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; IN VITRO STUDY; LRP6 GENE; MAJOR CLINICAL STUDY; MALE; METABOLIC REGULATION; METABOLIC SYNDROME X; MISSENSE MUTATION; OSTEOPOROSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; RISK FACTOR;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SUBSTITUTION; ANIMALS; CHROMOSOMES, HUMAN, PAIR 12; CORONARY DISEASE; FAMILY HEALTH; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LDL-RECEPTOR RELATED PROTEINS; LINKAGE (GENETICS); LIPIDS; MALE; METABOLIC SYNDROME X; MICE; MIDDLE AGED; MUTATION, MISSENSE; NIH 3T3 CELLS; OSTEOPOROSIS; PEDIGREE; RISK FACTORS; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 33847656105     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1136370     Document Type: Article

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