-
1
-
-
0033959997
-
Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease?
-
Anderton B.H., Dayanandan R., Killick R., Lovestone S. Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease? Mol. Med. Today. 6:2000;54-59.
-
(2000)
Mol. Med. Today
, vol.6
, pp. 54-59
-
-
Anderton, B.H.1
Dayanandan, R.2
Killick, R.3
Lovestone, S.4
-
2
-
-
0035665719
-
The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation
-
Bax B., Carter P.S., Lewis C., Guy A.R., Bridges A., Tanner R., Pettman G., Mannix C., Culbert A.A., Brown M.J., Smith D.G., Reith A.D. The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation. Structure (Camb. 9:2001;1143-1152.
-
(2001)
Structure (Camb.
, vol.9
, pp. 1143-1152
-
-
Bax, B.1
Carter, P.S.2
Lewis, C.3
Guy, A.R.4
Bridges, A.5
Tanner, R.6
Pettman, G.7
Mannix, C.8
Culbert, A.A.9
Brown, M.J.10
Smith, D.G.11
Reith, A.D.12
-
3
-
-
0031456158
-
Wnt signaling: A common theme in animal development
-
Cadigan K.M., Nusse R. Wnt signaling: a common theme in animal development. Genes Dev. 11:1997;3286-3305.
-
(1997)
Genes Dev.
, vol.11
, pp. 3286-3305
-
-
Cadigan, K.M.1
Nusse, R.2
-
4
-
-
0032573083
-
Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17
-
Clark L.N., Poorkaj P., Wszolek Z., Geschwind D.H., Nasreddine Z.S., Miller B., Li D., Payami H., Awert F., Markopoulou K., Andreadis A., D'Souza I., Lee V.M., Reed L., Trojanowski J.Q., Zhukareva V., Bird T., Schellenberg G., Wilhelmsen K.C. Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17. Proc. Natl. Acad. Sci. USA. 95:1998;13103-13107.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13103-13107
-
-
Clark, L.N.1
Poorkaj, P.2
Wszolek, Z.3
Geschwind, D.H.4
Nasreddine, Z.S.5
Miller, B.6
Li, D.7
Payami, H.8
Awert, F.9
Markopoulou, K.10
Andreadis, A.11
D'Souza, I.12
Lee, V.M.13
Reed, L.14
Trojanowski, J.Q.15
Zhukareva, V.16
Bird, T.17
Schellenberg, G.18
Wilhelmsen, K.C.19
-
5
-
-
0024820904
-
Poly(A) addition during maturation of frog oocytes: Distinct nuclear and cytoplasmic activities and regulation by the sequence UUUUUAU
-
Fox C.A., Sheets M.D., Wickens M.P. Poly(A) addition during maturation of frog oocytes: distinct nuclear and cytoplasmic activities and regulation by the sequence UUUUUAU. Genes Dev. 3:1989;2151-2162.
-
(1989)
Genes Dev.
, vol.3
, pp. 2151-2162
-
-
Fox, C.A.1
Sheets, M.D.2
Wickens, M.P.3
-
6
-
-
0037127255
-
Identification of the Axin and Frat binding region of glycogen synthase kinase-3
-
Fraser E., Young N., Dajani R., Franca-Koh J., Ryves J., Williams R.S., Yeo M., Webster M.T., Richardson C., Smalley M.J., Pearl L.H., Harwood A., Dale T.C. Identification of the Axin and Frat binding region of glycogen synthase kinase-3. J. Biol. Chem. 277:2002;2176-2185.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2176-2185
-
-
Fraser, E.1
Young, N.2
Dajani, R.3
Franca-Koh, J.4
Ryves, J.5
Williams, R.S.6
Yeo, M.7
Webster, M.T.8
Richardson, C.9
Smalley, M.J.10
Pearl, L.H.11
Harwood, A.12
Dale, T.C.13
-
7
-
-
0035879410
-
Molecular approaches to cerebral laterality: Development and neurodegeneration
-
Geschwind D.H., Miller B.L. Molecular approaches to cerebral laterality: development and neurodegeneration. Am. J. Med. Genet. 101:2001;370-381.
-
(2001)
Am. J. Med. Genet.
, vol.101
, pp. 370-381
-
-
Geschwind, D.H.1
Miller, B.L.2
-
8
-
-
17744370294
-
A genetic analysis of neural progenitor differentiation
-
Geschwind D.H., Ou J., Easterday M.C., Dougherty J.D., Jackson R.L., Chen Z., Antoine H., Terskikh A., Weissman I.L., Nelson S.F., Kornblum H.I. A genetic analysis of neural progenitor differentiation. Neuron. 29:2001;325-339.
-
(2001)
Neuron
, vol.29
, pp. 325-339
-
-
Geschwind, D.H.1
Ou, J.2
Easterday, M.C.3
Dougherty, J.D.4
Jackson, R.L.5
Chen, Z.6
Antoine, H.7
Terskikh, A.8
Weissman, I.L.9
Nelson, S.F.10
Kornblum, H.I.11
-
9
-
-
0032837303
-
Frequency of tau mutations in three series of non-Alzheimer's degenerative dementia
-
Houlden H., Baker M., Adamson J., Grover A., Waring S., Dickson D., Lynch T., Boeve B., Petersen R.C., Pickering-Brown S., Owen F., Neary D., Craufurd D., Snowden J., Mann D., Hutton M. Frequency of tau mutations in three series of non-Alzheimer's degenerative dementia. Ann. Neurol. 46:1999;243-248.
-
(1999)
Ann. Neurol.
, vol.46
, pp. 243-248
-
-
Houlden, H.1
Baker, M.2
Adamson, J.3
Grover, A.4
Waring, S.5
Dickson, D.6
Lynch, T.7
Boeve, B.8
Petersen, R.C.9
Pickering-Brown, S.10
Owen, F.11
Neary, D.12
Craufurd, D.13
Snowden, J.14
Mann, D.15
Hutton, M.16
-
10
-
-
0032543684
-
Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
-
Hutton M., Lendon C.L., Rizzu P., Baker M., Froelich S., Houlden H., Pickering-Brown S., Chakraverty S., Isaacs A., Grover A., Hackett J., Adamson J., Lincoln S., Dickson D., Davies P., Petersen R.C., Stevens M., de Graaff E., Wauters E., van Baren J., Hillebrand M., Joosse M., Kwon J.M., Nowotny P., Heutink P., et al. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17. Nature. 393:1998;702-705.
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
Houlden, H.6
Pickering-Brown, S.7
Chakraverty, S.8
Isaacs, A.9
Grover, A.10
Hackett, J.11
Adamson, J.12
Lincoln, S.13
Dickson, D.14
Davies, P.15
Petersen, R.C.16
Stevens, M.17
De Graaff, E.18
Wauters, E.19
Van Baren, J.20
Hillebrand, M.21
Joosse, M.22
Kwon, J.M.23
Nowotny, P.24
Heutink, P.25
more..
-
11
-
-
0037118247
-
Human wild-type Tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
-
Jackson G.R., Wiedau-Pazos M., Sang T.K., Wagle N., Brown C.A., Massachi S., Geschwind D.H. Human wild-type Tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron. 34:2002;509-519.
-
(2002)
Neuron
, vol.34
, pp. 509-519
-
-
Jackson, G.R.1
Wiedau-Pazos, M.2
Sang, T.K.3
Wagle, N.4
Brown, C.A.5
Massachi, S.6
Geschwind, D.H.7
-
12
-
-
0022552131
-
Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
-
Kozak M. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell. 44:1986;283-292.
-
(1986)
Cell
, vol.44
, pp. 283-292
-
-
Kozak, M.1
-
13
-
-
0023665902
-
An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs
-
Kozak M. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15:1987;8125-8148.
-
(1987)
Nucleic Acids Res
, vol.15
, pp. 8125-8148
-
-
Kozak, M.1
-
14
-
-
0026342613
-
An analysis of vertebrate mRNA sequences: Intimations of translational control
-
Kozak M. An analysis of vertebrate mRNA sequences: intimations of translational control. J. Cell Biol. 115:1991;887-903.
-
(1991)
J. Cell Biol.
, vol.115
, pp. 887-903
-
-
Kozak, M.1
-
15
-
-
0033061571
-
Initiation of translation in prokaryotes and eukaryotes
-
Kozak M. Initiation of translation in prokaryotes and eukaryotes. Gene. 234:1999;187-208.
-
(1999)
Gene
, vol.234
, pp. 187-208
-
-
Kozak, M.1
-
16
-
-
0344245499
-
Expression analysis of glycogen synthase kinase-3 in human tissues
-
Lau K.F., Miller C.C., Anderton B.H., Shaw P.C. Expression analysis of glycogen synthase kinase-3 in human tissues. J. Pept. Res. 54:1999;85-91.
-
(1999)
J. Pept. Res.
, vol.54
, pp. 85-91
-
-
Lau, K.F.1
Miller, C.C.2
Anderton, B.H.3
Shaw, P.C.4
-
18
-
-
0028675873
-
Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells
-
Lovestone S., Reynolds C.H., Latimer D., Davis D.R., Anderton B.H., Gallo J.M., Hanger D., Mulot S., Marquardt B., Stabel S., et al. Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Curr. Biol. 4:1994;1077-1086.
-
(1994)
Curr. Biol.
, vol.4
, pp. 1077-1086
-
-
Lovestone, S.1
Reynolds, C.H.2
Latimer, D.3
Davis, D.R.4
Anderton, B.H.5
Gallo, J.M.6
Hanger, D.7
Mulot, S.8
Marquardt, B.9
Stabel, S.10
-
19
-
-
0024687134
-
Poly(A) elongation during Xenopus oocyte maturation is required for translational recruitment and is mediated by a short sequence element
-
McGrew L.L., Dworkin-Rastl E., Dworkin M.B., Richter J.D. Poly(A) elongation during Xenopus oocyte maturation is required for translational recruitment and is mediated by a short sequence element. Genes Dev. 3:1989;803-815.
-
(1989)
Genes Dev.
, vol.3
, pp. 803-815
-
-
McGrew, L.L.1
Dworkin-Rastl, E.2
Dworkin, M.B.3
Richter, J.D.4
-
20
-
-
0035404265
-
Translational control by CPEB: A means to the end
-
Mendez R., Richter J.D. Translational control by CPEB: a means to the end. Nat. Rev. Mol. Cell Biol. 2:2001;521-529.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 521-529
-
-
Mendez, R.1
Richter, J.D.2
-
21
-
-
14444284106
-
Tau is a candidate gene for chromosome 17 frontotemporal dementia [published erratum appears in Ann. Neurol. 1998 Sep; 44(3): 428]
-
Poorkaj P., Bird T.D., Wijsman E., Nemens E., Garruto R.M., Anderson L., Andreadis A., Wiederholt W.C., Raskind M., Schellenberg G.D. Tau is a candidate gene for chromosome 17 frontotemporal dementia [published erratum appears in Ann. Neurol. 1998 Sep; 44(3): 428]. Ann. Neurol. 43:1998;815-825.
-
(1998)
Ann. Neurol.
, vol.43
, pp. 815-825
-
-
Poorkaj, P.1
Bird, T.D.2
Wijsman, E.3
Nemens, E.4
Garruto, R.M.5
Anderson, L.6
Andreadis, A.7
Wiederholt, W.C.8
Raskind, M.9
Schellenberg, G.D.10
-
22
-
-
0034781576
-
Presence of ATG triplets in 5′ untranslated regions of eukaryotic cDNAs correlates with a 'weak' context of the start codon
-
Rogozin I.B., Kochetov A.V., Kondrashov F.A., Koonin E.V., Milanesi L. Presence of ATG triplets in 5′ untranslated regions of eukaryotic cDNAs correlates with a 'weak' context of the start codon. Bioinformatics. 17:2001;890-900.
-
(2001)
Bioinformatics
, vol.17
, pp. 890-900
-
-
Rogozin, I.B.1
Kochetov, A.V.2
Kondrashov, F.A.3
Koonin, E.V.4
Milanesi, L.5
-
23
-
-
0032193702
-
Isolation and chromosomal mapping of human glycogen synthase kinase-3 alpha and -3 beta encoding genes
-
Shaw P.C., Davies A.F., Lau K.F., Garcia-Barcelo M., Waye M.M., Lovestone S., Miller C.C., Anderton B.H. Isolation and chromosomal mapping of human glycogen synthase kinase-3 alpha and -3 beta encoding genes. Genome. 41:1998;720-727.
-
(1998)
Genome
, vol.41
, pp. 720-727
-
-
Shaw, P.C.1
Davies, A.F.2
Lau, K.F.3
Garcia-Barcelo, M.4
Waye, M.M.5
Lovestone, S.6
Miller, C.C.7
Anderton, B.H.8
-
24
-
-
0027075193
-
Translational control by poly(A) elongation during Xenopus development: Differential repression and enhancement by a novel cytoplasmic polyadenylation element
-
Simon R., Tassan J.P., Richter J.D. Translational control by poly(A) elongation during Xenopus development: differential repression and enhancement by a novel cytoplasmic polyadenylation element. Genes Dev. 6:1992;2580-2591.
-
(1992)
Genes Dev.
, vol.6
, pp. 2580-2591
-
-
Simon, R.1
Tassan, J.P.2
Richter, J.D.3
-
25
-
-
0028981873
-
Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells
-
Sperber B.R., Leight S., Goedert M., Lee V.M. Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells. Neurosci Lett. 197:1995;149-153.
-
(1995)
Neurosci Lett.
, vol.197
, pp. 149-153
-
-
Sperber, B.R.1
Leight, S.2
Goedert, M.3
Lee, V.M.4
-
26
-
-
0003374626
-
Tau protein pathology in neurodegenerative diseases
-
Spillantini M.G., Goedert M. Tau protein pathology in neurodegenerative diseases. Trends Neurosci. 21:1998;428-433.
-
(1998)
Trends Neurosci.
, vol.21
, pp. 428-433
-
-
Spillantini, M.G.1
Goedert, M.2
-
27
-
-
0032821768
-
A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin
-
Thomas G.M., Frame S., Goedert M., Nathke I., Polakis P., Cohen P. A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin. FEBS Lett. 458:1999;247-251.
-
(1999)
FEBS Lett.
, vol.458
, pp. 247-251
-
-
Thomas, G.M.1
Frame, S.2
Goedert, M.3
Nathke, I.4
Polakis, P.5
Cohen, P.6
-
28
-
-
0034764497
-
Irresistible IRES. Attracting the translation machinery to internal ribosome entry sites
-
Vagner S., Galy B., Pyronnet S. Irresistible IRES. Attracting the translation machinery to internal ribosome entry sites. EMBO Rep. 2:2001;893-898.
-
(2001)
EMBO Rep.
, vol.2
, pp. 893-898
-
-
Vagner, S.1
Galy, B.2
Pyronnet, S.3
-
29
-
-
0032566623
-
Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase
-
Wang J.Z., Wu Q., Smith A., Grundke-Iqbal I., Iqbal K. Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase. FEBS Lett. 436:1998;28-34.
-
(1998)
FEBS Lett.
, vol.436
, pp. 28-34
-
-
Wang, J.Z.1
Wu, Q.2
Smith, A.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
30
-
-
0032215079
-
CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses
-
Wu L., Wells D., Tay J., Mendis D., Abbott M.A., Barnitt A., Quinlan E., Heynen A., Fallon J.R., Richter J.D. CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses. Neuron. 21:1998;1129-1139.
-
(1998)
Neuron
, vol.21
, pp. 1129-1139
-
-
Wu, L.1
Wells, D.2
Tay, J.3
Mendis, D.4
Abbott, M.A.5
Barnitt, A.6
Quinlan, E.7
Heynen, A.8
Fallon, J.R.9
Richter, J.D.10
-
31
-
-
0032521599
-
Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation
-
Zheng-Fischhofer Q., Biernat J., Mandelkow E.M., Illenberger S., Godemann R., Mandelkow E. Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation. Eur. J. Biochem. 252:1998;542-552.
-
(1998)
Eur. J. Biochem.
, vol.252
, pp. 542-552
-
-
Zheng-Fischhofer, Q.1
Biernat, J.2
Mandelkow, E.M.3
Illenberger, S.4
Godemann, R.5
Mandelkow, E.6
|