Ion channel remodeling in vascular smooth muscle during hypertension: Implications for novel therapeutic approaches

Pharmacological Research

Volumn 70, Issue 1, 2013, Pages 126-138

  Joseph, Biny K ^a   Thakali, Keshari M ^b,c   Moore, Christopher L ^c   Rhee, Sung W ^c  

^a Venenum Biodesign   (United States)

^b ARKANSAS CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Calcium channel; Gene therapy; Hypertension; Ion channel; Potassium channel; Vascular smooth muscle cell

Indexed keywords

ADENOVIRUS VECTOR; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL CAV1.2; CALCIUM CHANNEL L TYPE; DIHYDROPYRIDINE DERIVATIVE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; POTASSIUM CHANNEL; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

CALCIUM TRANSPORT; CONTROLLED STUDY; DNA POLYMORPHISM; DRUG EFFICACY; EDEMA; GENE EXPRESSION; GENE SILENCING; GENE THERAPY; HUMAN; HYPERTENSION; MEMBRANE CONDUCTANCE; MEMBRANE DEPOLARIZATION; MEMBRANE STEADY POTENTIAL; NONHUMAN; PATHOGENESIS; PHARMACOLOGICAL BLOCKING; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REVIEW; TACHYCARDIA; UPREGULATION; VASCULAR SMOOTH MUSCLE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; ANTIHYPERTENSIVE AGENTS; CALCIUM CHANNELS; HUMANS; HYPERTENSION; ION CHANNEL GATING; MOLECULAR TARGETED THERAPY; MUSCLE, SMOOTH, VASCULAR; POTASSIUM CHANNELS; PROTEIN SUBUNITS;

EID: 84875188087     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2013.01.008     Document Type: Review

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