Intracellular mechanisms involved in vascular remodelling of resistance arteries in hypertension: Role of angiotensin II

Experimental Physiology

Volumn 90, Issue 4, 2005, Pages 449-455

  Touyz, Rhian M ^a,b  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN RECEPTOR; CALCIUM CHANNEL; CALCIUM ION; DIACYLGLYCEROL; FOCAL ADHESION KINASE; GROWTH FACTOR; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHOLIPASE C; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; REACTIVE OXYGEN METABOLITE; REDOX EFFECTOR FACTOR 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SUPEROXIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VASOACTIVE AGENT;

ANOIKIS; APOPTOSIS; ARTERY MEDIA; BLOOD VESSEL REMODELING; BLOOD VESSEL TONE; CELL DIFFERENTIATION; CELL GROWTH; CELL MIGRATION; CONFERENCE PAPER; EXTRACELLULAR MATRIX; HUMAN; HYPERTENSION; INFLAMMATION; MACROPHAGE; NONHUMAN; RESISTANCE BLOOD VESSEL; TISSUE REPAIR; TISSUE STRUCTURE; VASCULAR SMOOTH MUSCLE;

EID: 22144435873     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1113/expphysiol.2005.030080     Document Type: Conference Paper

References (34)

1. Berk BC (2001). Vascular smooth muscle growth: autocrine growth mechanisms. Physiol Rev 81, 999-1030.
2. De Mey JGR, Schiffers PM, Hilgers RHP & Sanders MW (2005). Toward functional genomics of flow-induced outward remodeling of resistance arteries. Am J Physiol Heart Circ Physiol 288, 1022-1027.
3. Diep QN, Amiri F, Touyz RM, Cohn JS, Endemann D, Neves MF & Schiffrin EL (2002). PPARa activator effects on Ang II-induced vascular oxidative stress and inflammation. Hypertension 40, 866-871.
4. Eguchi S & Inagami T (2000). Signal transduction of angiotensin II type 1 receptor through receptor tyrosine kinase. Regul Pept 91, 13-20.
5. Griendling KK (2004). Novel NAD(P)H oxidases in the cardiovascular system. Heart 90, 491-493.
6. Griendling KK, Minieri CA, Ollerenshaw JD & Alexander RW (1994). Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 74, 1141-1148.
7. Hamilton CA, Miller WH, Al-Benna S, Brosnan MJ, Drummond RD, McBride MW & Dominiczak AF (2004). Strategies to reduce oxidative stress in cardiovascular disease. Clin Sci 106, 219-234.
8. Harrison D, Griendling KK, Landmesser U, Hornig B & Drexler H (2003). Role of oxidative stress in atherosclerosis. Am J Cardiol 91, 7-11.
9. Hilenski LL, Clempus RE, Quinn MT, Lambeth JD & Griendling KK (2004). Distinct subcellular localizations of nox1 and nox4 in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 24, 677-683.
10. Hlubocka Z, Umnerova V, Heller S, Peleska J, Jindra A, Jachymova M, Kvasnicka J, Horky K & Aschermann M (2002). Circulating intercellular cell adhesion molecule-1, endothelin-1 and von Willebrand factor-markers of endothelial dysfunction in uncomplicated essential hypertension: the effect of treatment with ACE inhibitors. J Hum Hypertens 16, 557-562.
11. Intengan HD & Schiffrin EL (2001). Vascular remodeling in hypertension: roles of apoptosis, inflammation, and fibrosis. Hypertension 38, 581-587.
12. Lassegue B & Clempus RE (2003). Vascular NAD(P)H oxidases: specific features, expression, and regulation. Am J Physiol Regul Integr Comp Physiol 285, R277-R297.
13. Mulvany MJ, Baumbach GL, Aalkjaer C, Heagerty AM, Korsgaard N, Schiffrin EL & Heistad DD (1996). Vascular remodeling. Hypertension 28, 505-506.
14. Murphy TJ, Alexander RW, Griendling KK, Runge MS & Bernstein KE (1991). Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor. Nature 351, 233-236.
15. Nathan C (2003). Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling. J Clin Invest 111, 769-778.
16. Pueyo ME, Gonzalez W, Nicoletti A, Savoie F, Arnal JF & Michel JB (2000). Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress. Arterioscler Thromb Vasc Biol 20, 645-651.
17. Rey FE & Pagano PJ (2002). The reactive adventitia: fibroblast oxidase in vascular function. Arterioscler Thromb Vasc Biol 22, 1962-1971.
18. Saito Y & Berk BC (2001). Transactivation: a novel signaling pathway from angiotensin II to tyrosine kinase receptors. J Mol Cell Cardiol 33, 3-7.
19. San Jose G, Moreno MU, Olivan S, Beloqui O, Fortuno A, Diez J & Zalba G (2004). Functional effect of the p22phox -930A/G polymorphism on p22phox expression and NADPH oxidase activity in hypertension. Hypertension 44, 163-169.
20. Sanz-Rosa D, Oubina MP, Cediel E, de Las Heras N, Vegazo O, Jimenez J, Lahera V & Cachofeiro V (2005). Effect of AT1 receptor antagonism on vascular and circulating inflammatory mediators in SHR: role of NF-kappaB/IkappaB system. Am J Physiol Heart Circ Physiol 288, H111-H115.
21. Schiffrin EL & Touyz RM (2004). From bedside to bench to bedside: role of renin-angiotensin-aldosterone system in remodeling of resistance arteries in hypertension. Am J Physiol Heart Circ Physiol 287, H435-H446.
22. Suematsu M, Suzuki H, DeLano FA & Schmid-Schonbein GW (2002). The inflammatory aspect of the microcirculation in hypertension: oxidative stress, leukocytes/endothelial interaction, apoptosis. Microcirculation 9, 259-276.
23. Taniyama Y & Griendling KK (2003). Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension 42, 1075-1081.
24. Tanoue T & Nishida E (2003). Molecular recognitions in the MAP kinase cascades. Cell Signal 15, 455-462.
25. Touyz RM (2000). Oxidative stress and vascular damage in hypertension. Curr Hypertens Rep 2, 98-105.
26. Touyz RM, Chen X, He G, Quinn MT & Schiffrin EL (2002a). Expression of a gp91phox-containing leukocyte-type NADPH oxidase in human vascular smooth muscle cells - modulation by Ang II. Circles 90, 1205-1213.
27. Touyz RM, He G, Deng LY & Schiffrin EL (1999). Role of extracellular signal-regulated kinases in angiotensin II-stimulated contraction of smooth muscle cells from human resistance arteries. Circulation 99, 392-399.
28. Touyz RM, He G, Wu XH, Park JB, M & Schiffrin EL (2001a). Src is an important mediator of extracellular signal-regulated kinase 1/2-dependent growth signaling by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients. Hypertension 38, 56-64.
29. Touyz RM & Schiffrin EL (2000). Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev 52, 639-672.
30. 2+ signaling by angiotensin II in human vascular smooth muscle cells. J Hypertens 19, 441-449.
31. Touyz RM, Wu XH, He G, Salomon S & Schiffrin EL (2002b). Increased angiotensin II-mediated Src signaling via epidermal growth factor receptor transactivation is associated with decreased c-terminal Src kinase activity in vascular smooth muscle cells from spontaneously hypertensive rats. Hypertension 39, 479-485.
32. Touyz RM, Yao G & Schiffrin EL (2003). c-Src induces phosphorylation and translocation of p47phox - role in Superoxide generation by angiotensin II in human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 23, 981-987.
33. Virdis A, Neves MF, Amiri F, Touyz RM & Schiffrin EL (2004). Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice. J Hypertens 22, 535-542.
34. Virdis A & Schiffrin EL (2003). Vascular inflammation: a role in vascular disease in hypertension? Curr Opin Nephrol Hypertens 12, 181-187.