The β3 subunit contributes to vascular calcium channel upregulation and hypertension in angiotensin II-infused C57BL/6 mice

Hypertension

Volumn 61, Issue 1, 2013, Pages 137-142

  Kharade, Sujay V ^a   Sonkusare, Swapnil K ^a   Srivastava, Anup K ^a   Thakali, Keshari M ^a   Fletcher, Terry W ^a   Rhee, Sung W ^a   Rusch, Nancy J ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

3 subunit; a1C subunit; calcium channel; hypertension; mesenteric arteries

Indexed keywords

ANGIOTENSIN II; CALCIUM; CALCIUM CHANNEL L TYPE; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED CALCIUM CHANNEL L TYPE BETA 1.2 SUBUNIT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; GENE DELETION; HYPERTENSION; MESENTERIC ARTERY; MOUSE; NONHUMAN; PATHOGENESIS; PRESSOR RESPONSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; SMOOTH MUSCLE TONE; SYSTOLIC BLOOD PRESSURE; UPREGULATION; VASCULAR SMOOTH MUSCLE; WILD TYPE;

ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; CALCIUM; CALCIUM CHANNELS, L-TYPE; HYPERTENSION; MESENTERIC ARTERIES; MICE; MICE, INBRED C57BL; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; UP-REGULATION;

EID: 84871616330     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.112.197863     Document Type: Article

References (28)

1. 2+ channels: is membrane depolarization the signal? Circ Res. 2004;94:e97-104.
2. 2+ channels in mesenteric and skeletal arteries of SHR. Hypertension. 2002;40:214-219. (Pubitemid 34840101)
3. v1.2 channels in spontaneously hypertensive rats. Am J Hypertens. 2006;19:823-831. (Pubitemid 44107686)
4. Sonkusare S, Fraer M, Marsh JD, Rusch NJ. Disrupting calcium channel expression to lower blood pressure: new targeting of a well-known channel. Mol Interv. 2006;6:304-310. (Pubitemid 46046940)
5. Hayashi K, Epstein M, Loutzenhiser R. Enhanced myogenic responsiveness of renal interlobular arteries in spontaneously hypertensive rats. Hypertension. 1992;19:153-160.
6. 2+ channels in cerebral smooth muscle with renal hypertension. Circ Res. 1998;82:1330-1337. (Pubitemid 28294753)
7. Hutri-Kähönen N, Kähönen M, Wu X, Sand J, Nordback I, Taurio J, Pörsti I. Control of vascular tone in isolated mesenteric arterial segments from hypertensive patients. Br J Pharmacol. 1999;127:1735-1743. (Pubitemid 29369011)
8. Hulthén UL, Bolli P, Amann FW, Kiowski W, Bühler FR. Enhanced vaso-dilatation in essential hypertension by calcium channel blockade with verapamil. Hypertension. 1982;4(3 pt 2):26-31.
9. MacGregor GA, Rotellar C, Markandu ND, Smith SJ, Sagnella GA. Contrasting effects of nifedipine, captopril, and propranolol in normoten-sive and hypertensive subjects. J Cardiovasc Pharmacol. 1982;4(suppl 3):S358-S362. (Pubitemid 13173983)
10. Ishii H, Itoh K, Nose T. Different antihypertensive effects of nifedipine in conscious experimental hypertensive and normotensive rats. Eur J Pharmacol. 1980;64:21-29. (Pubitemid 10123934)
11. Takata Y, Hutchinson JS. Exaggerated hypotensive responses to calcium antagonists in spontaneously hypertensive rats. Clin Exp Hypertens A. 1983;5:827-847. (Pubitemid 13026503)
12. Bannister JP, Adebiyi A, Zhao G, Narayanan D, Thomas CM, Feng JY, Jaggar JH. Smooth muscle cell a2ô-1 subunits are essential for vasoregu-lation by CaV1.2 channels. Circ Res. 2009;105:948-955.
13. 2+ channels. Nature. 2004;429:675-680. (Pubitemid 38812321)
14. Sonkusare S, Palade PT, Marsh JD, Telemaque S, Pesic A, Rusch NJ. Vascular calcium channels and high blood pressure: pathophysiology and therapeutic implications. Vascul Pharmacol. 2006;44:131-142. (Pubitemid 43185988)
15. Van Petegem F, Clark KA, Chatelain FC, Minor DL Jr. Structure of a complex between a voltage-gated calcium channel β-subunit and an a-subunit domain. Nature. 2004;429:671-675. (Pubitemid 38812320)
16. Murakami M, Yamamura H, Murakami A, Okamura T, Nunoki K, Mitui-Saito M, Muraki K, Hano T, Imaizumi Y, Flockerzi T, Yanagisawa T. Conserved smooth muscle contractility and blood pressure increase in response to high-salt diet in mice lacking the β3 subunit of the voltage-dependent calcium channel. J Cardiovasc Pharmacol. 2000;36 (suppl 2):S69-S73. (Pubitemid 32150668)
17. 2+ channel β3 subunit. J Biol Chem. 2003;278:43261-43267. (Pubitemid 37345946)
18. Hall JE. Historical perspective of the renin-angiotensin system. Mol Biotechnol. 2003;24:27-39. (Pubitemid 36578042)
19. Chien AJ, Gao T, Perez-Reyes E, Hosey MM. Membrane targeting of L-type calcium channels. Role of palmitoylation in the subcellular localization of the β2a subunit. J Biol Chem. 1998;273:23590-23597. (Pubitemid 28417553)
20. Brice NL, Berrow NS, Campbell V, Page KM, Brickley K, Tedder I, Dolphin AC. Importance of the different β subunits in the membrane expression of the a1A and a2 calcium channel subunits: studies using a depolarization- sensitive a1A antibody. Eur J Neurosci. 1997;9:749-759. (Pubitemid 27190084)
21. Ball SL, Powers PA, Shin HS, Morgans CW, Peachey NS, Gregg RG. Role of the β(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer. Invest Ophthalmol Vis Sci. 2002;43:1595-1603. (Pubitemid 34462663)
22. Fan QI, Vanderpool KM, O'Connor J, Marsh JD. Decoy calcium channel β subunits modulate contractile function in myocytes. Mol Cell Biochem. 2003;242:3-10. (Pubitemid 36240522)
23. Altier C, Garcia-Caballero A, Simms B, You H, Chen L, Walcher J, Tedford HW, Hermosilla T, Zamponi GW. The Cavβ subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels. Nat Neurosci. 2011;14:173-180.
24. Waithe D, Ferron L, Page KM, Chaggar K, Dolphin AC. Beta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation. J Biol Chem. 2011;286:9598-9611.
25. Rougier JS, Albesa M, Abriel H, Viard P. Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized Ca(V)1.2 calcium channels. J Biol Chem. 2011;286:8829-8838.
26. Dolphin AC. Calcium channel diversity: multiple roles of calcium channel subunits. Curr Opin Neurobiol. 2009;19:237-244.
27. Cingolani E, Ramirez Correa GA, Kizana E, Murata M, Cho HC, Marbán E. Gene therapy to inhibit the calcium channel β subunit: physiological consequences and pathophysiological effects in models of cardiac hypertrophy. Circ Res. 2007;101:166-175. (Pubitemid 47196584)
28. 2+ channels in cardiac cells. J Pharmacol Exp Ther. 2008;325:37-46. (Pubitemid 351439151)