Intracellular Ca2+ silences L-type Ca2+ channels in mesenteric veins: Mechanism of venous smooth muscle resistance to calcium channel blockers

Circulation Research

Volumn 106, Issue 4, 2010, Pages 739-747

  Thakali, Keshari M ^a   Kharade, Sujay V ^a   Sonkusare, Swapnil K ^b   Rhee, Sung W ^a   Stimers, Joseph R ^a   Rusch, Nancy J ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF VERMONT   (United States)

Author keywords

Arteries; Channels; L type Ca2+; Veins

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; ALPHA ACTIN; CAFFEINE; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; NIFEDIPINE; RYANODINE; THAPSIGARGIN; CHELATING AGENT; ENZYME INHIBITOR; L TYPE CALCIUM CHANNEL ALPHA(1C); L-TYPE CALCIUM CHANNEL ALPHA(1C); POTASSIUM CHLORIDE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; VASOCONSTRICTOR AGENT; VASODILATOR AGENT;

ANIMAL CELL; ANIMAL TISSUE; ARTERY TONE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM TRANSPORT; CHELATION; CONTROLLED STUDY; DEPOLARIZATION; HEART AFTERLOAD; HEART PRELOAD; MALE; MESENTERIC ARTERY; MESENTERIC VEIN; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE; VASOCONSTRICTION; VEIN RESISTANCE; VEIN TONE; WESTERN BLOTTING; ANIMAL; CELL MEMBRANE POTENTIAL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG RESISTANCE; METABOLISM; SPRAGUE DAWLEY RAT; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ANIMALS; BLOTTING, WESTERN; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CHELATING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; ENZYME INHIBITORS; MALE; MEMBRANE POTENTIALS; MESENTERIC ARTERIES; MESENTERIC VEINS; MUSCLE, SMOOTH, VASCULAR; NIFEDIPINE; PATCH-CLAMP TECHNIQUES; POTASSIUM CHLORIDE; RATS; RATS, SPRAGUE-DAWLEY; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 77949353713     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.206763     Document Type: Article

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