Activation of NFATc3 down-regulates the β1 subunit of large conductance, calcium-activated K+ channels in arterial smooth muscle and contributes to hypertension

Journal of Biological Chemistry

Volumn 282, Issue 5, 2007, Pages 3231-3240

  Nieves Cintrón, Madeline ^a   Amberg, Gregory C ^a   Nichols, C Blake ^a   Molkentin, Jeffery D ^b   Santana, Luis F ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTERIAL SMOOTH MUSCLE; CONTRACTILE STATE; HYPERTENSION;

CALCIUM COMPOUNDS; CHEMICAL ACTIVATION; GENE EXPRESSION; PROTEINS; SENSITIVITY ANALYSIS;

MUSCLE;

CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM ION; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR NFAT; ANGIOTENSIN II; CALCIUM; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; NFATC3 PROTEIN, MOUSE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY MUSCLE; ARTICLE; BETA CHAIN; BLOOD PRESSURE REGULATION; CALCIUM CONDUCTANCE; CONTROLLED STUDY; DISEASE SEVERITY; DOWN REGULATION; ENZYME ACTIVATION; HYPERTENSION; HYPOTHESIS; IN VIVO STUDY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STIMULATION; WILD TYPE; ANIMAL; BLOOD PRESSURE; BRAIN ARTERY; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GENETICS; MESENTERIC ARTERY; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; VASCULAR SMOOTH MUSCLE;

MUS;

ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; CALCIUM; CEREBRAL ARTERIES; HYPERTENSION; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MESENTERIC ARTERIES; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; NFATC TRANSCRIPTION FACTORS; SIGNAL TRANSDUCTION;

EID: 34047265484     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608822200     Document Type: Article

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