Intracellular Ca2+ inhibits smooth muscle L-type Ca2+ channels by activation of protein phosphatase type 2B and by direct interaction with the channel

Journal of General Physiology

Volumn 110, Issue 5, 1997, Pages 503-513

  Schuhmann, Klaus ^a   Romanin, Christoph ^b   Baumgartner, Werner ^b   Groschner, Klaus ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b JOHANNES KEPLER UNIVERSITY LINZ   (Austria)

Author keywords

Gating; L type Ca2+ channels; Patch clamp; Protein phosphatase 2B; Vascular smooth muscle

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 4 NITROPHENYLPHOSPHATASE; ADENOSINE TRIPHOSPHATE; BARIUM ION; CALCIMYCIN; CALCINEURIN; CALCIUM CHANNEL; CALCIUM ION; CALPASTATIN; CYCLOSPORIN A; CYTOCHALASIN B; PHOSPHOPROTEIN PHOSPHATASE; UNCLASSIFIED DRUG; CALCIUM; CYCLOSPORIN;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL PH; CONTROLLED STUDY; CYTOSKELETON; DEPHOSPHORYLATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NEGATIVE FEEDBACK; PATCH CLAMP; UMBILICAL VEIN; VASCULAR SMOOTH MUSCLE; VOLTAGE CLAMP; CHANNEL GATING; DRUG EFFECT; INTRACELLULAR MEMBRANE; METABOLISM; PHYSIOLOGY;

CALCINEURIN; CALCIUM; CALCIUM CHANNELS; CYCLOSPORINE; ENZYME ACTIVATION; HUMANS; INTRACELLULAR MEMBRANES; ION CHANNEL GATING; MUSCLE, SMOOTH, VASCULAR; PATCH-CLAMP TECHNIQUES;

EID: 0030611692     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.110.5.503     Document Type: Article

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