Computer modeling of siRNA knockdown effects indicates an essential role of the Ca2+ channel α2δ-1 subunit in cardiac excitation-contraction coupling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 26, 2007, Pages 11091-11096

  Tuluc, Petronel ^a   Kern, Georg ^a   Obermair, Gerald J ^a   Flucher, Bernhard E ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Action potential; Calcium; Dysgenic myotube; Heart

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL L TYPE; GREEN FLUORESCENT PROTEIN; SMALL INTERFERING RNA;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CHANNEL GATING; COMPUTER MODEL; CONTROLLED STUDY; EXCITATION CONTRACTION COUPLING; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOPLASMIC RETICULUM;

ACTION POTENTIALS; ANIMALS; CALCIUM; CALCIUM CHANNELS; CELL MEMBRANE; COMPUTER SIMULATION; ELECTROPHYSIOLOGY; HEART VENTRICLES; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RABBITS; RNA, SMALL INTERFERING; SARCOPLASMIC RETICULUM;

EID: 34547427802     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0700577104     Document Type: Article

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