메뉴 건너뛰기




Volumn 13, Issue 1, 2013, Pages 131-139

Follicular helper T cells: New insights into mechanisms of autoimmune diseases

Author keywords

Antibody formation; Autoimmune diseases; Germinal center

Indexed keywords

AUTOANTIBODY; B7 RELATED PROTEIN 1 ANTIBODY; CD4 ANTIGEN; CD40 LIGAND; CHEMOKINE RECEPTOR CXCR5; CYTOKINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; IMMUNOGLOBULIN FC FRAGMENT; INDUCIBLE T CELL COSTIMULATOR; INTERLEUKIN 21; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN ANTIBODY; PROTEIN BCL 6; UNCLASSIFIED DRUG;

EID: 84875167019     PISSN: 15245012     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (71)

References (75)
  • 1
    • 0034606359 scopus 로고    scopus 로고
    • Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
    • Dec 4
    • Breitfeld D, Ohl L, Kremmer E, et al. Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production. J Exp Med. 2000 Dec 4; 192(11):1545-1552.
    • (2000) J Exp Med. , vol.192 , Issue.11 , pp. 1545-1552
    • Breitfeld, D.1    Ohl, L.2    Kremmer, E.3
  • 3
    • 0030938144 scopus 로고    scopus 로고
    • Germinal center development
    • Apr
    • Liu YJ, Arpin C. Germinal center development. Immunol Rev. 1997 Apr;156:111-126.
    • (1997) Immunol Rev. , vol.156 , pp. 111-126
    • Liu, Y.J.1    Arpin, C.2
  • 4
    • 34548036949 scopus 로고    scopus 로고
    • Germinal-center organization and cellular dynamics
    • Aug
    • Allen CD, Okada T, Cyster JG. Germinal-center organization and cellular dynamics. Immunity. 2007 Aug;27(2):190-202.
    • (2007) Immunity , vol.27 , Issue.2 , pp. 190-202
    • Allen, C.D.1    Okada, T.2    Cyster, J.G.3
  • 6
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH)
    • Crotty S. Follicular helper CD4 T cells (TFH). Annu Rev Immunol. 2011;29:621-663.
    • (2011) Annu Rev Immunol. , vol.29 , pp. 621-663
    • Crotty, S.1
  • 7
    • 82055177182 scopus 로고    scopus 로고
    • How T cells earn the follicular rite of passage
    • Nov 23
    • Vinuesa CG, Cyster JG. How T cells earn the follicular rite of passage. Immunity. 2011 Nov 23;35(5):671-680.
    • (2011) Immunity , vol.35 , Issue.5 , pp. 671-680
    • Vinuesa, C.G.1    Cyster, J.G.2
  • 8
    • 84859720726 scopus 로고    scopus 로고
    • T-follicular helper cell differentiation and the co-option of this pathway by non-helper cells
    • May
    • Linterman MA, Liston A, Vinuesa CG. T-follicular helper cell differentiation and the co-option of this pathway by non-helper cells. Immunol Rev. 2012 May;247(1):143-159.
    • (2012) Immunol Rev. , vol.247 , Issue.1 , pp. 143-159
    • Linterman, M.A.1    Liston, A.2    Vinuesa, C.G.3
  • 9
    • 84862016703 scopus 로고    scopus 로고
    • Taming lupus-a new understanding of pathogenesis is leading to clinical advances
    • Jun 6
    • Liu Z, Davidson A. Taming lupus-a new understanding of pathogenesis is leading to clinical advances. Nat Med. 2012 Jun 6;18(6):871-882.
    • (2012) Nat Med. , vol.18 , Issue.6 , pp. 871-882
    • Liu, Z.1    Davidson, A.2
  • 10
    • 74849138095 scopus 로고    scopus 로고
    • Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
    • Jan
    • Simpson N, Gatenby PA, Wilson A, et al. Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis Rheum. 2010 Jan;62(1):234-244.
    • (2010) Arthritis Rheum. , vol.62 , Issue.1 , pp. 234-244
    • Simpson, N.1    Gatenby, P.A.2    Wilson, A.3
  • 11
    • 84988833343 scopus 로고    scopus 로고
    • Circulating T helper cells in patients with systemic lupus erythematosus share the phenotypic properties with lymphoid T follicular helper cells. [abstract]
    • Oct
    • Lindwall E, Gauthier C, Alarakhia A, et al. Circulating T helper cells in patients with systemic lupus erythematosus share the phenotypic properties with lymphoid T follicular helper cells. [abstract]. Arthritis Rheum. 2011 Oct;63(10):646.
    • (2011) Arthritis Rheum. , vol.63 , Issue.10 , pp. 646
    • Lindwall, E.1    Gauthier, C.2    Alarakhia, A.3
  • 12
    • 84861670170 scopus 로고    scopus 로고
    • Role of the frequency of blood CD4(+) CXCR5(+) CCR6(+) T cells in autoimmunity in patients with Sjögren's syndrome
    • Jun 1 Epub 2012 Apr 30
    • Li XY, Wu ZB, Ding J, et al. Role of the frequency of blood CD4(+) CXCR5(+) CCR6(+) T cells in autoimmunity in patients with Sjögren's syndrome. Biochem Biophys Res Commun. 2012 Jun 1;422(2):238-244. Epub 2012 Apr 30.
    • (2012) Biochem Biophys Res Commun. , vol.422 , Issue.2 , pp. 238-244
    • Li, X.Y.1    Wu, Z.B.2    Ding, J.3
  • 13
    • 79251521021 scopus 로고    scopus 로고
    • Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion
    • Jan 28; Epub 2011 Jan 6. Erratum in: Immunity. 2011 Jan 28;34(1):135
    • Morita R, Schmitt N, Bentebibel SE, et al. Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion. Immunity. 2011 Jan 28;34(1):108-121. Epub 2011 Jan 6. Erratum in: Immunity. 2011 Jan 28;34(1):135.
    • (2011) Immunity , vol.34 , Issue.1 , pp. 108-121
    • Morita, R.1    Schmitt, N.2    Bentebibel, S.E.3
  • 14
    • 84988875599 scopus 로고    scopus 로고
    • Identification of follicular helper T cells as a novel cell population potentially involved in the pathogenesis of rheumatoid arthritis. [abstract]
    • Oct
    • Ing S, Alarakhia A, Lindwall E, et al. Identification of follicular helper T cells as a novel cell population potentially involved in the pathogenesis of rheumatoid arthritis. [abstract]. Arthritis Rheum. 2012 Oct;64(10):1195.
    • (2012) Arthritis Rheum. , vol.64 , Issue.10 , pp. 1195
    • Ing, S.1    Alarakhia, A.2    Lindwall, E.3
  • 15
    • 84862298255 scopus 로고    scopus 로고
    • Increased frequency of circulating follicular helper T cells in patients with rheumatoid arthritis
    • Epub 2012 May 10
    • Ma J, Zhu C, Ma B, et al. Increased frequency of circulating follicular helper T cells in patients with rheumatoid arthritis. Clin Dev Immunol. 2012;2012:827480. Epub 2012 May 10.
    • (2012) Clin Dev Immunol. , vol.2012 , pp. 827480
    • Ma, J.1    Zhu, C.2    Ma, B.3
  • 16
    • 0035554935 scopus 로고    scopus 로고
    • Separable effector T cell populations specialized for B cell help or tissue inflammation
    • Sep
    • Campbell DJ, Kim CH, Butcher EC. Separable effector T cell populations specialized for B cell help or tissue inflammation. Nat Immunol. 2001 Sep;2(9):876-881.
    • (2001) Nat Immunol. , vol.2 , Issue.9 , pp. 876-881
    • Campbell, D.J.1    Kim, C.H.2    Butcher, E.C.3
  • 17
    • 0036885067 scopus 로고    scopus 로고
    • The lineage decisions of helper T cells
    • Dec
    • Murphy KM, Reiner SL. The lineage decisions of helper T cells. Nat Rev Immunol. 2002 Dec;2(12):933-944.
    • (2002) Nat Rev Immunol. , vol.2 , Issue.12 , pp. 933-944
    • Murphy, K.M.1    Reiner, S.L.2
  • 18
    • 0034606348 scopus 로고    scopus 로고
    • CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function
    • Dec 4
    • Schaerli P, Willimann K, Lang AB, Lipp M, Loetscher P, Moser B. CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function. J Exp Med. 2000 Dec 4;192(11): 1553-1562.
    • (2000) J Exp Med. , vol.192 , Issue.11 , pp. 1553-1562
    • Schaerli, P.1    Willimann, K.2    Lang, A.B.3    Lipp, M.4    Loetscher, P.5    Moser, B.6
  • 19
    • 0035908122 scopus 로고    scopus 로고
    • Subspecialization of CXCR5+T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells
    • Jun 18
    • Kim CH, Rott LS, Clark-Lewis I, Campbell DJ, Wu L, Butcher EC. Subspecialization of CXCR5+T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells. J Exp Med. 2001 Jun 18;193(12):1373-1381.
    • (2001) J Exp Med. , vol.193 , Issue.12 , pp. 1373-1381
    • Kim, C.H.1    Rott, L.S.2    Clark-Lewis, I.3    Campbell, D.J.4    Wu, L.5    Butcher, E.C.6
  • 20
    • 0035804268 scopus 로고    scopus 로고
    • ICOS is critical for CD40-mediated antibody class switching
    • Jan 4
    • McAdam AJ, Greenwald RJ, Levin MA, et al. ICOS is critical for CD40-mediated antibody class switching. Nature. 2001 Jan 4; 409(6816):102-105.
    • (2001) Nature , vol.409 , Issue.6816 , pp. 102-105
    • McAdam, A.J.1    Greenwald, R.J.2    Levin, M.A.3
  • 21
    • 23444434705 scopus 로고    scopus 로고
    • The role of ICOS in the CXCR5+follicular B helper T cell maintenance in vivo
    • Aug 15
    • Akiba H, Takeda K, Kojima Y, et al. The role of ICOS in the CXCR5+follicular B helper T cell maintenance in vivo. J Immunol. 2005 Aug 15;175(4):2340-2348.
    • (2005) J Immunol. , vol.175 , Issue.4 , pp. 2340-2348
    • Akiba, H.1    Takeda, K.2    Kojima, Y.3
  • 22
    • 0035804269 scopus 로고    scopus 로고
    • ICOS is essential for effective T-helper-cell responses
    • Jan 4
    • Tafuri A, Shahinian A, Bladt F, et al. ICOS is essential for effective T-helper-cell responses. Nature. 2001 Jan 4;409(6816):105-109.
    • (2001) Nature , vol.409 , Issue.6816 , pp. 105-109
    • Tafuri, A.1    Shahinian, A.2    Bladt, F.3
  • 23
    • 0035804254 scopus 로고    scopus 로고
    • ICOS co-stimulatory receptor is essential for T-cell activation and function
    • Jan 4
    • Dong C, Juedes AE, Temann UA, et al. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature. 2001 Jan 4;409(6816):97-101.
    • (2001) Nature , vol.409 , Issue.6816 , pp. 97-101
    • Dong, C.1    Juedes, A.E.2    Temann, U.A.3
  • 24
    • 58449124804 scopus 로고    scopus 로고
    • The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
    • Feb Epub 2008 Dec 21
    • Bauquet AT, Jin H, Paterson AM, et al. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat Immunol. 2009 Feb;10(2):167-175. Epub 2008 Dec 21.
    • (2009) Nat Immunol. , vol.10 , Issue.2 , pp. 167-175
    • Bauquet, A.T.1    Jin, H.2    Paterson, A.M.3
  • 25
    • 70350743827 scopus 로고    scopus 로고
    • PD-1 and CTLA-4 inhibitory cosignaling pathways in HIV infection and the potential for therapeutic intervention
    • May 15
    • Kaufmann DE, Walker BD. PD-1 and CTLA-4 inhibitory cosignaling pathways in HIV infection and the potential for therapeutic intervention. J Immunol. 2009 May 15;182(10):5891-5897.
    • (2009) J Immunol. , vol.182 , Issue.10 , pp. 5891-5897
    • Kaufmann, D.E.1    Walker, B.D.2
  • 26
    • 84875158548 scopus 로고    scopus 로고
    • PD-1 and BTLA and CD8(+) T-cell "exhaustion" in cancer: "Exercising" an alternative viewpoint
    • Aug 1
    • Haymaker C, Wu R, Bernatchez C, Radvanyi L. PD-1 and BTLA and CD8(+) T-cell "exhaustion" in cancer: "Exercising" an alternative viewpoint. Oncoimmunology. 2012 Aug 1;1(5):735-738.
    • (2012) Oncoimmunology , vol.1 , Issue.5 , pp. 735-738
    • Haymaker, C.1    Wu, R.2    Bernatchez, C.3    Radvanyi, L.4
  • 27
    • 84866098957 scopus 로고    scopus 로고
    • The development and function of follicular helper T cells in immune responses
    • Sep Epub 2012 Jun 4
    • Chen M, Guo Z, Ju W, et al. The development and function of follicular helper T cells in immune responses. Cell Mol Immunol. 2012 Sep;9(5):375-379. Epub 2012 Jun 4.
    • (2012) Cell Mol Immunol. , vol.9 , Issue.5 , pp. 375-379
    • Chen, M.1    Guo, Z.2    Ju, W.3
  • 28
    • 84867045163 scopus 로고    scopus 로고
    • Role of the PD-1 pathway in the immune response
    • Oct Epub 2012 Aug 17
    • Riella LV, Paterson AM, Sharpe AH, Chandraker A. Role of the PD-1 pathway in the immune response. Am J Transplant. 2012 Oct;12(10):2575-2587. Epub 2012 Aug 17.
    • (2012) Am J Transplant. , vol.12 , Issue.10 , pp. 2575-2587
    • Riella, L.V.1    Paterson, A.M.2    Sharpe, A.H.3    Chandraker, A.4
  • 29
    • 77952557954 scopus 로고    scopus 로고
    • PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells
    • Jun Epub 2010 May 9
    • Good-Jacobson KL, Szumilas CG, Chen L, et al. PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells. Nat Immunol. 2010 Jun;11(6):535-542. Epub 2010 May 9.
    • (2010) Nat Immunol. , vol.11 , Issue.6 , pp. 535-542
    • Good-Jacobson, K.L.1    Szumilas, C.G.2    Chen, L.3
  • 30
    • 0028135424 scopus 로고
    • Humoral immune responses in CD40 ligand-deficient mice
    • Nov 1
    • Renshaw BR, Fanslow WC III, Armitage RJ, et al. Humoral immune responses in CD40 ligand-deficient mice. J Exp Med. 1994 Nov 1;180(5):1889-1900.
    • (1994) J Exp Med. , vol.180 , Issue.5 , pp. 1889-1900
    • Renshaw, B.R.1    Fanslow III, W.C.2    Armitage, R.J.3
  • 31
    • 0028447437 scopus 로고
    • The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation
    • Jun
    • Kawabe T, Naka T, Yoshida K, et al. The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity. 1994 Jun;1(3):167-178.
    • (1994) Immunity , vol.1 , Issue.3 , pp. 167-178
    • Kawabe, T.1    Naka, T.2    Yoshida, K.3
  • 32
    • 22544440345 scopus 로고    scopus 로고
    • Human CD57+ germinal center-T cells are the major helpers for GC-B cells and induce class switch recombination
    • Feb 4
    • Kim JR, Lim HW, Kang SG, Hillsamer P, Kim CH. Human CD57+ germinal center-T cells are the major helpers for GC-B cells and induce class switch recombination. BMC Immunol. 2005 Feb 4;6: 3.
    • (2005) BMC Immunol. , vol.6 , pp. 3
    • Kim, J.R.1    Lim, H.W.2    Kang, S.G.3    Hillsamer, P.4    Kim, C.H.5
  • 33
    • 78049354525 scopus 로고    scopus 로고
    • B and T lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immune responses
    • Sep 1 Epub 2010 Jul 26
    • Kashiwakuma D, Suto A, Hiramatsu Y, et al. B and T lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immune responses. J Immunol. 2010 Sep 1;185(5):2730-2736. Epub 2010 Jul 26.
    • (2010) J Immunol. , vol.185 , Issue.5 , pp. 2730-2736
    • Kashiwakuma, D.1    Suto, A.2    Hiramatsu, Y.3
  • 34
    • 76949091588 scopus 로고    scopus 로고
    • Optimal germinal center responses require a multistage T cell: B cell adhesion process involving integrins, SLAM-associated protein, and CD84
    • Feb 26 Epub 2010 Feb 11
    • Cannons JL, Qi H, Lu KT, et al. Optimal germinal center responses require a multistage T cell: B cell adhesion process involving integrins, SLAM-associated protein, and CD84. Immunity. 2010 Feb 26;32(2):253-265. Epub 2010 Feb 11.
    • (2010) Immunity , vol.32 , Issue.2 , pp. 253-265
    • Cannons, J.L.1    Qi, H.2    Lu, K.T.3
  • 35
    • 38049101408 scopus 로고    scopus 로고
    • Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: Predominant role of IL-21 produced by CXCR5+ T follicular helper cells
    • Dec 15
    • Bryant VL, Ma CS, Avery DT, et al. Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells. J Immunol. 2007 Dec 15;179(12):8180-8190.
    • (2007) J Immunol. , vol.179 , Issue.12 , pp. 8180-8190
    • Bryant, V.L.1    Ma, C.S.2    Avery, D.T.3
  • 36
    • 65549114338 scopus 로고    scopus 로고
    • IL-4-producing CD4+T cells in reactive lymph nodes during helminth infection are T follicular helper cells
    • May 11 Epub 2009 Apr 20
    • King IL, Mohrs M. IL-4-producing CD4+T cells in reactive lymph nodes during helminth infection are T follicular helper cells. J Exp Med. 2009 May 11;206(5):1001-1007. Epub 2009 Apr 20.
    • (2009) J Exp Med. , vol.206 , Issue.5 , pp. 1001-1007
    • King, I.L.1    Mohrs, M.2
  • 37
    • 79956159047 scopus 로고    scopus 로고
    • Elevated circulating CD4+ ICOS+ Foxp3+ T cells contribute to overproduction of IL-10 and are correlated with disease severity in patients with systemic lupus erythematosus
    • May
    • Liu Y, Zhu T, Cai G, et al. Elevated circulating CD4+ ICOS+ Foxp3+ T cells contribute to overproduction of IL-10 and are correlated with disease severity in patients with systemic lupus erythematosus. Lupus. 2011 May;20(6):620-627.
    • (2011) Lupus , vol.20 , Issue.6 , pp. 620-627
    • Liu, Y.1    Zhu, T.2    Cai, G.3
  • 38
    • 73149085517 scopus 로고    scopus 로고
    • IL-21 and IL-10 have redundant roles but differential capacities at different stages of plasma cell generation from human germinal center B cells
    • Dec Epub 2009 Sep 17
    • Yoon SO, Zhang X, Berner P, Choi YS. IL-21 and IL-10 have redundant roles but differential capacities at different stages of plasma cell generation from human germinal center B cells. J Leukoc Biol. 2009 Dec;86(6):1311-1318. Epub 2009 Sep 17.
    • (2009) J Leukoc Biol. , vol.86 , Issue.6 , pp. 1311-1318
    • Yoon, S.O.1    Zhang, X.2    Berner, P.3    Choi, Y.S.4
  • 39
    • 29144519767 scopus 로고    scopus 로고
    • IL-21 induces differentiation of human naive and memory B cells into antibodysecreting plasma cells
    • Dec 15
    • Ettinger R, Sims GP, Fairhurst AM, et al. IL-21 induces differentiation of human naive and memory B cells into antibodysecreting plasma cells. J Immunol. 2005 Dec 15;175(12):7867-7879.
    • (2005) J Immunol. , vol.175 , Issue.12 , pp. 7867-7879
    • Ettinger, R.1    Sims, G.P.2    Fairhurst, A.M.3
  • 40
    • 38049110981 scopus 로고    scopus 로고
    • Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration
    • Nov 1
    • Kuchen S, Robbins R, Sims GP, et al. Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration. Immunol. 2007 Nov 1;179(9): 5886-5896.
    • (2007) Immunol , vol.179 , Issue.9 , pp. 5886-5896
    • Kuchen, S.1    Robbins, R.2    Sims, G.P.3
  • 41
    • 46749151286 scopus 로고    scopus 로고
    • Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
    • Jul 18 Epub 2008 Jul 3
    • Nurieva RI, Chung Y, Hwang D, et al. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity. 2008 Jul 18;29(1): 138-149. Epub 2008 Jul 3.
    • (2008) Immunity , vol.29 , Issue.1 , pp. 138-149
    • Nurieva, R.I.1    Chung, Y.2    Hwang, D.3
  • 42
    • 45149123617 scopus 로고    scopus 로고
    • Development and characterization of IL-21-producing CD4+ T cells
    • Jun 9 Epub 2008 May 12
    • Suto A, Kashiwakuma D, Kagami S, et al. Development and characterization of IL-21-producing CD4+ T cells. J Exp Med. 2008 Jun 9;205(6):1369-1379. Epub 2008 May 12.
    • (2008) J Exp Med. , vol.205 , Issue.6 , pp. 1369-1379
    • Suto, A.1    Kashiwakuma, D.2    Kagami, S.3
  • 43
    • 79952637807 scopus 로고    scopus 로고
    • IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation
    • Mar 14
    • Eto D, Lao C, DiToro D, et al. IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation. PLoS One. 2011 Mar 14;6(3):e17739.
    • (2011) PLoS One. , vol.6 , Issue.3
    • Eto, D.1    Lao, C.2    DiToro, D.3
  • 44
    • 0030923519 scopus 로고    scopus 로고
    • Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein
    • Sep 30
    • Dhordain P, Albagli O, Lin RJ, et al. Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10762-10767.
    • (1997) Proc Natl Acad Sci U S A. , vol.94 , Issue.20 , pp. 10762-10767
    • Dhordain, P.1    Albagli, O.2    Lin, R.J.3
  • 45
    • 0442276480 scopus 로고    scopus 로고
    • Transcriptional control of B cell development and function
    • Feb 18
    • Bartholdy B, Matthias P. Transcriptional control of B cell development and function. Gene. 2004 Feb 18;327(1):1-23.
    • (2004) Gene , vol.327 , Issue.1 , pp. 1-23
    • Bartholdy, B.1    Matthias, P.2
  • 46
    • 0345505646 scopus 로고    scopus 로고
    • Inhibition of Th2 differentiation and GATA-3 expression by BCL-6
    • Mar 1
    • Kusam S, Toney LM, Sato H, Dent AL. Inhibition of Th2 differentiation and GATA-3 expression by BCL-6. J Immunol. 2003 Mar 1;170(5):2435-2441.
    • (2003) J Immunol. , vol.170 , Issue.5 , pp. 2435-2441
    • Kusam, S.1    Toney, L.M.2    Sato, H.3    Dent, A.L.4
  • 47
    • 0036078187 scopus 로고    scopus 로고
    • Role for Bcl-6 in the generation and maintenance of memory CD8+ T cells
    • Jun Epub 2002 May 20
    • Ichii H, Sakamoto A, Hatano M, et al. Role for Bcl-6 in the generation and maintenance of memory CD8+ T cells. Nat Immunol. 2002 Jun;3(6):558-563. Epub 2002 May 20.
    • (2002) Nat Immunol. , vol.3 , Issue.6 , pp. 558-563
    • Ichii, H.1    Sakamoto, A.2    Hatano, M.3
  • 48
    • 0030901289 scopus 로고    scopus 로고
    • Control of inflammation, cytokine expression, and germinal center formation by BCL-6
    • Apr 25
    • Dent AL, Shaffer AL, Yu X, Allman D, Staudt LM. Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science. 1997 Apr 25;276(5312):589-592.
    • (1997) Science , vol.276 , Issue.5312 , pp. 589-592
    • Dent, A.L.1    Shaffer, A.L.2    Yu, X.3    Allman, D.4    Staudt, L.M.5
  • 49
    • 17144439800 scopus 로고    scopus 로고
    • The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
    • Jun
    • Ye BH, Cattoretti G, Shen Q, et al. The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nat Genet. 1997 Jun;16(2):161-170.
    • (1997) Nat Genet. , vol.16 , Issue.2 , pp. 161-170
    • Ye, B.H.1    Cattoretti, G.2    Shen, Q.3
  • 50
    • 0036644712 scopus 로고    scopus 로고
    • Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis
    • Jul 1
    • Luther SA, Bidgol A, Hargreaves DC, et al. Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis. J Immunol. 2002 Jul 1;169(1):424-433.
    • (2002) J Immunol. , vol.169 , Issue.1 , pp. 424-433
    • Luther, S.A.1    Bidgol, A.2    Hargreaves, D.C.3
  • 51
    • 38049144850 scopus 로고    scopus 로고
    • Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation
    • Oct 15
    • Haynes NM, Allen CD, Lesley R, et al. Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation. J Immunol. 2007 Oct 15;179(8):5099-5108.
    • (2007) J Immunol. , vol.179 , Issue.8 , pp. 5099-5108
    • Haynes, N.M.1    Allen, C.D.2    Lesley, R.3
  • 52
    • 4644219817 scopus 로고    scopus 로고
    • Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5
    • Sep Epub 2004 Aug 1
    • Allen CD, Ansel KM, Low C, et al. Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5. Nat Immunol. 2004 Sep;5(9):943-952. Epub 2004 Aug 1.
    • (2004) Nat Immunol. , vol.5 , Issue.9 , pp. 943-952
    • Allen, C.D.1    Ansel, K.M.2    Low, C.3
  • 53
    • 0036169940 scopus 로고    scopus 로고
    • CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity
    • Jan
    • Ansel KM, Harris RB, Cyster JG. CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity. Immunity. 2002 Jan;16(1):67-76.
    • (2002) Immunity , vol.16 , Issue.1 , pp. 67-76
    • Ansel, K.M.1    Harris, R.B.2    Cyster, J.G.3
  • 54
    • 79960342424 scopus 로고    scopus 로고
    • B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells
    • Jul 4 Epub 2011 Jun 27
    • Lee SK, Rigby RJ, Zotos D, et al. B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells. J Exp Med. 2011 Jul 4;208(7):1377-1388. Epub 2011 Jun 27.
    • (2011) J Exp Med. , vol.208 , Issue.7 , pp. 1377-1388
    • Lee, S.K.1    Rigby, R.J.2    Zotos, D.3
  • 55
    • 0034606348 scopus 로고    scopus 로고
    • CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function
    • Dec 4
    • Schaerli P, Willimann K, Lang AB, et al. CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function. J Exp Med. 2000 Dec 4;192(11):1553-1562.
    • (2000) J Exp Med. , vol.192 , Issue.11 , pp. 1553-1562
    • Schaerli, P.1    Willimann, K.2    Lang, A.B.3
  • 56
    • 62849126473 scopus 로고    scopus 로고
    • The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding
    • Apr Epub 2009 Mar 1
    • Fazilleau N, McHeyzer-Williams LJ, Rosen H, McHeyzer-Williams MG. The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding. Nat Immunol. 2009 Apr;10(4):375-384. Epub 2009 Mar 1.
    • (2009) Nat Immunol. , vol.10 , Issue.4 , pp. 375-384
    • Fazilleau, N.1    McHeyzer-Williams, L.J.2    Rosen, H.3    McHeyzer-Williams, M.G.4
  • 57
    • 77955898582 scopus 로고    scopus 로고
    • T cells and follicular dendritic cells in germinal center B-cell formation and selection
    • Sep
    • Vinuesa CG, Linterman MA, Goodnow CC, Randall KL. T cells and follicular dendritic cells in germinal center B-cell formation and selection. Immunol Rev. 2010 Sep;237(1):72-89.
    • (2010) Immunol Rev. , vol.237 , Issue.1 , pp. 72-89
    • Vinuesa, C.G.1    Linterman, M.A.2    Goodnow, C.C.3    Randall, K.L.4
  • 58
    • 77957256910 scopus 로고    scopus 로고
    • The elusive identity of T follicular helper cells
    • Oct Epub 2010 Aug 31
    • Yu D, Vinuesa CG. The elusive identity of T follicular helper cells. Trends Immunol. 2010 Oct;31(10):377-383. Epub 2010 Aug 31.
    • (2010) Trends Immunol. , vol.31 , Issue.10 , pp. 377-383
    • Yu, D.1    Vinuesa, C.G.2
  • 59
    • 0035399564 scopus 로고    scopus 로고
    • The distinct roles of T cell-derived cytokines and a novel follicular dendritic cell-signaling molecule 8D6 in germinal center-B cell differentiation
    • Jul 1
    • Zhang X, Li L, Jung J, et al. The distinct roles of T cell-derived cytokines and a novel follicular dendritic cell-signaling molecule 8D6 in germinal center-B cell differentiation. J Immunol. 2001 Jul 1;167(1):49-56.
    • (2001) J Immunol. , vol.167 , Issue.1 , pp. 49-56
    • Zhang, X.1    Li, L.2    Jung, J.3
  • 60
    • 41549131849 scopus 로고    scopus 로고
    • T follicular helper (TFH) cells in normal and dysregulated immune responses
    • King C, Tangye SG, Mackay CR. T follicular helper (TFH) cells in normal and dysregulated immune responses. Annu Rev Immunol. 2008;26:741-766.
    • (2008) Annu Rev Immunol. , vol.26 , pp. 741-766
    • King, C.1    Tangye, S.G.2    McKay, C.R.3
  • 61
    • 70049101558 scopus 로고    scopus 로고
    • The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment
    • Sep 18 Epub 2009 Jul 23
    • Yu D, Rao S, Tsai LM, et al. The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity. 2009 Sep 18;31(3):457-468. Epub 2009 Jul 23.
    • (2009) Immunity , vol.31 , Issue.3 , pp. 457-468
    • Yu, D.1    Rao, S.2    Tsai, L.M.3
  • 62
    • 69249101229 scopus 로고    scopus 로고
    • Bcl6 mediates the development of T follicular helper cells
    • Aug 21 Epub 2009 Jul 23
    • Nurieva RI, Chung Y, Martinez GJ, et al. Bcl6 mediates the development of T follicular helper cells. Science. 2009 Aug 21; 325(5943):1001-1005. Epub 2009 Jul 23.
    • (2009) Science , vol.325 , Issue.5943 , pp. 1001-1005
    • Nurieva, R.I.1    Chung, Y.2    Martinez, G.J.3
  • 63
    • 69249109601 scopus 로고    scopus 로고
    • Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
    • Aug 21 Epub 2009 Jul 16
    • Johnston RJ, Poholek AC, DiToro D, et al. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science. 2009 Aug 21;325(5943):1006-1010. Epub 2009 Jul 16.
    • (2009) Science , vol.325 , Issue.5943 , pp. 1006-1010
    • Johnston, R.J.1    Poholek, A.C.2    DiToro, D.3
  • 64
    • 38349178776 scopus 로고    scopus 로고
    • Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
    • Feb Epub 2007 Dec 23
    • Hsu HC, Yang P, Wang J, et al. Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat Immunol. 2008 Feb; 9(2):166-175. Epub 2007 Dec 23.
    • (2008) Nat Immunol. , vol.9 , Issue.2 , pp. 166-175
    • Hsu, H.C.1    Yang, P.2    Wang, J.3
  • 65
    • 0034798017 scopus 로고    scopus 로고
    • Spontaneous formation of germinal centers in autoimmune mice
    • Oct
    • Luzina IG, Atamas SP, Storrer CE, et al. Spontaneous formation of germinal centers in autoimmune mice. J Leukoc Biol. 2001 Oct; 70(4):578-584.
    • (2001) J Leukoc Biol. , vol.70 , Issue.4 , pp. 578-584
    • Luzina, I.G.1    Atamas, S.P.2    Storrer, C.E.3
  • 66
    • 21144438325 scopus 로고    scopus 로고
    • A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
    • May 26
    • Vinuesa CG, Cook MC, Angelucci C, et al. A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature. 2005 May 26;435(7041):452-458.
    • (2005) Nature , vol.435 , Issue.7041 , pp. 452-458
    • Vinuesa, C.G.1    Cook, M.C.2    Angelucci, C.3
  • 67
    • 63449096041 scopus 로고    scopus 로고
    • Follicular helper T cells are required for systemic autoimmunity
    • Mar 16 Epub 2009 Feb 16
    • Linterman MA, Rigby RJ, Wong RK, et al. Follicular helper T cells are required for systemic autoimmunity. J Exp Med. 2009 Mar 16;206(3):561-576. Epub 2009 Feb 16.
    • (2009) J Exp Med. , vol.206 , Issue.3 , pp. 561-576
    • Linterman, M.A.1    Rigby, R.J.2    Wong, R.K.3
  • 68
    • 60849107595 scopus 로고    scopus 로고
    • A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice
    • Feb 3 Epub 2009 Jan 21
    • Bubier JA, Sproule TJ, Foreman O, et al. A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1518-1523. Epub 2009 Jan 21.
    • (2009) Proc Natl Acad Sci U S A. , vol.106 , Issue.5 , pp. 1518-1523
    • Bubier, J.A.1    Sproule, T.J.2    Foreman, O.3
  • 69
    • 33745168605 scopus 로고    scopus 로고
    • Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
    • Jun 16 Epub 2006 May 18
    • Pisitkun P, Deane JA, Difilippantonio MJ, et al. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science. 2006 Jun 16;312(5780):1669-1672. Epub 2006 May 18.
    • (2006) Science , vol.312 , Issue.5780 , pp. 1669-1672
    • Pisitkun, P.1    Deane, J.A.2    Difilippantonio, M.J.3
  • 70
    • 84856880967 scopus 로고    scopus 로고
    • IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice
    • Feb 15 Epub 2012 Jan 9
    • Rankin AL, Guay H, Herber D, et al. IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice. J Immunol. 2012 Feb 15;188(4): 1656-1667. Epub 2012 Jan 9.
    • (2012) J Immunol. , vol.188 , Issue.4 , pp. 1656-1667
    • Rankin, A.L.1    Guay, H.2    Herber, D.3
  • 71
    • 0026080802 scopus 로고
    • Characterization of somatically mutated S107 VH11-encoded anti-DNA autoantibodies derived from autoimmune (NZB x NZW)F1 mice
    • Mar 1
    • Behar SM, Lustgarten DL, Corbet S, Scharff MD. Characterization of somatically mutated S107 VH11-encoded anti-DNA autoantibodies derived from autoimmune (NZB x NZW)F1 mice. J Exp Med. 1991 Mar 1;173(3):731-741.
    • (1991) J Exp Med. , vol.173 , Issue.3 , pp. 731-741
    • Behar, S.M.1    Lustgarten, D.L.2    Corbet, S.3    Scharff, M.D.4
  • 72
    • 0037144519 scopus 로고    scopus 로고
    • Evolution of autoantibody responses via somatic hypermutation outside of germinal centers
    • Sep 20
    • William J, Euler C, Christensen S, Shlomchik MJ. Evolution of autoantibody responses via somatic hypermutation outside of germinal centers. Science. 2002 Sep 20;297(5589):2066-2070.
    • (2002) Science , vol.297 , Issue.5589 , pp. 2066-2070
    • William, J.1    Euler, C.2    Christensen, S.3    Shlomchik, M.J.4
  • 73
    • 77956410939 scopus 로고    scopus 로고
    • Abatacept limits breach of self-tolerance in a murine model of arthritis via effects on the generation of T follicular helper cells
    • Aug 1 Epub 2010 Jul 2
    • Platt AM, Gibson VB, Patakas A, et al. Abatacept limits breach of self-tolerance in a murine model of arthritis via effects on the generation of T follicular helper cells. J Immunol. 2010 Aug 1; 185(3):1558-1567. Epub 2010 Jul 2.
    • (2010) J Immunol. , vol.185 , Issue.3 , pp. 1558-1567
    • Platt, A.M.1    Gibson, V.B.2    Patakas, A.3
  • 74
    • 63149093151 scopus 로고    scopus 로고
    • B7RP-1 blockade ameliorates autoimmunity through regulation of follicular helper T cells
    • Feb 1
    • Hu YL, Metz DP, Chung J, Siu G, Zhang M. B7RP-1 blockade ameliorates autoimmunity through regulation of follicular helper T cells. J Immunol. 2009 Feb 1;182(3):1421-1428.
    • (2009) J Immunol. , vol.182 , Issue.3 , pp. 1421-1428
    • Hu, Y.L.1    Metz, D.P.2    Chung, J.3    Siu, G.4    Zhang, M.5
  • 75
    • 77951887482 scopus 로고    scopus 로고
    • Anti-programmed cell death 1 antibody reduces CD4+PD-1+ T cells and relieves the lupuslike nephritis of NZB/W F1 mice
    • Mar 1 Epub 2010 Feb 5
    • Kasagi S, Kawano S, Okazaki T, et al. Anti-programmed cell death 1 antibody reduces CD4+PD-1+ T cells and relieves the lupuslike nephritis of NZB/W F1 mice. J Immunol. 2010 Mar 1;184(5): 2337-47. Epub 2010 Feb 5.
    • (2010) J Immunol. , vol.184 , Issue.5 , pp. 2337-2347
    • Kasagi, S.1    Kawano, S.2    Okazaki, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.