-
1
-
-
40749111025
-
Effector CD8 T cell development: A balancing act between memory cell potential and terminal differentiation
-
Joshi, N.S. & Kaech, S.M. Effector CD8 T cell development: a balancing act between memory cell potential and terminal differentiation. J. Immunol. 180, 1309-1315 (2008).
-
(2008)
J. Immunol.
, vol.180
, pp. 1309-1315
-
-
Joshi, N.S.1
Kaech, S.M.2
-
2
-
-
0029052398
-
Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers
-
Han, S. et al. Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers. J. Immunol. 155, 556-567 (1995).
-
(1995)
J. Immunol.
, vol.155
, pp. 556-567
-
-
Han, S.1
-
3
-
-
0026060620
-
Intraclonal generation of antibody mutants in germinal centres
-
Jacob, J., Kelsoe, G., Rajewsky, K. & Weiss, U. Intraclonal generation of antibody mutants in germinal centres. Nature 354, 389-392 (1991).
-
(1991)
Nature
, vol.354
, pp. 389-392
-
-
Jacob, J.1
Kelsoe, G.2
Rajewsky, K.3
Weiss, U.4
-
4
-
-
0027305024
-
In situ studies of the primary immune response to (4-hydroxy-3- nitrophenyl)acetyl. III. the kinetics of v region mutation and selection in germinal center B cells
-
Jacob, J., Przylepa, J., Miller, C. & Kelsoe, G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells. J. Exp. Med. 178, 1293-1307 (1993).
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1293-1307
-
-
Jacob, J.1
Przylepa, J.2
Miller, C.3
Kelsoe, G.4
-
5
-
-
0033517153
-
Relaxed negative selection in germinal centers and impaired affnity maturation in bcl-xL transgenic mice
-
Takahashi, Y. et al. Relaxed negative selection in germinal centers and impaired affnity maturation in bcl-xL transgenic mice. J. Exp. Med. 190, 399-410 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 399-410
-
-
Takahashi, Y.1
-
6
-
-
0032536872
-
Situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. V. affnity maturation develops in two stages of clonal selection
-
Takahashi, Y., Dutta, P.R., Cerasoli, D.M. & Kelsoe, G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affnity maturation develops in two stages of clonal selection. J. Exp. Med. 187, 885-895 (1998).
-
(1998)
J. Exp. Med.
, vol.187
, pp. 885-895
-
-
Takahashi, Y.1
Dutta, P.R.2
Cerasoli, D.M.3
Kelsoe, G.4
-
7
-
-
0035913362
-
Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas
-
Pasqualucci, L. et al. Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas. Nature 412, 341-346 (2001).
-
(2001)
Nature
, vol.412
, pp. 341-346
-
-
Pasqualucci, L.1
-
8
-
-
63449096041
-
Follicular helper T cells are required for systemic autoimmunity
-
Linterman, M.A. et al. Follicular helper T cells are required for systemic autoimmunity. J. Exp. Med. 206, 561-576 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 561-576
-
-
Linterman, M.A.1
-
9
-
-
0027414691
-
CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome
-
Allen, R.C. et al. CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome. Science 259, 990-993 (1993).
-
(1993)
Science
, vol.259
, pp. 990-993
-
-
Allen, R.C.1
-
10
-
-
0344953578
-
Transcriptional analysis of the B cell germinal center reaction
-
Klein, U. et al. Transcriptional analysis of the B cell germinal center reaction. Proc. Natl. Acad. Sci. USA 100, 2639-2644 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2639-2644
-
-
Klein, U.1
-
11
-
-
47949091743
-
Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities
-
Tomayko, M.M. et al. Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities. J. Immunol. 181, 27-38 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 27-38
-
-
Tomayko, M.M.1
-
12
-
-
60549092755
-
Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells
-
Good, K.L., Avery, D.T. & Tangye, S.G. Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells. J. Immunol. 182, 890-901 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 890-901
-
-
Good, K.L.1
Avery, D.T.2
Tangye, S.G.3
-
13
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman, G.J. et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J. Exp. Med. 192, 1027-1034 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
-
14
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
Latchman, Y. et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat. Immunol. 2, 261-268 (2001).
-
(2001)
Nat. Immunol.
, vol.2
, pp. 261-268
-
-
Latchman, Y.1
-
15
-
-
57849168934
-
+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
-
+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nat. Immunol. 10, 29-37 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 29-37
-
-
Blackburn, S.D.1
-
16
-
-
34447646310
-
Programmed death-1 ligand 1 interacts specifcally with the B7-1 costimulatory molecule to inhibit T cell responses
-
Butte, M.J., Keir, M.E., Phamduy, T.B., Sharpe, A.H. & Freeman, G.J. Programmed death-1 ligand 1 interacts specifcally with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity 27, 111-122 (2007).
-
(2007)
Immunity
, vol.27
, pp. 111-122
-
-
Butte, M.J.1
Keir, M.E.2
Phamduy, T.B.3
Sharpe, A.H.4
Freeman, G.J.5
-
17
-
-
0037111483
-
Expression of programmed death 1 ligands by murine T cells and APC
-
Yamazaki, T. et al. Expression of programmed death 1 ligands by murine T cells and APC. J. Immunol. 169, 5538-5545 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 5538-5545
-
-
Yamazaki, T.1
-
19
-
-
2942755979
-
T follicular helper cells express a distinctive transcriptional profle, refecting their role as non-Th1/Th2 effector cells that provide help for B cells
-
Chtanova, T. et al. T follicular helper cells express a distinctive transcriptional profle, refecting their role as non-Th1/Th2 effector cells that provide help for B cells. J. Immunol. 173, 68-78 (2004).
-
(2004)
J. Immunol.
, vol.173
, pp. 68-78
-
-
Chtanova, T.1
-
20
-
-
33846635838
-
Imaging of germinal center selection events during affnity maturation
-
Allen, C.D., Okada, T., Tang, H.L. & Cyster, J.G. Imaging of germinal center selection events during affnity maturation. Science 315, 528-531 (2007).
-
(2007)
Science
, vol.315
, pp. 528-531
-
-
Allen, C.D.1
Okada, T.2
Tang, H.L.3
Cyster, J.G.4
-
21
-
-
0029971182
-
Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specifc B cell activation
-
Toellner, K.M., Gulbranson-Judge, A., Taylor, D.R., Sze, D.M. & MacLennan, I.C. Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specifc B cell activation. J. Exp. Med. 183, 2303-2312 (1996).
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2303-2312
-
-
Toellner, K.M.1
Gulbranson-Judge, A.2
Taylor, D.R.3
Sze, D.M.4
MacLennan, I.C.5
-
22
-
-
0025951891
-
Sites of specifc B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens
-
Liu, Y.J., Zhang, J., Lane, P.J., Chan, E.Y. & MacLennan, I.C. Sites of specifc B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur. J. Immunol. 21, 2951-2962 (1991).
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 2951-2962
-
-
Liu, Y.J.1
Zhang, J.2
Lane, P.J.3
Chan, E.Y.4
MacLennan, I.C.5
-
23
-
-
34247884612
-
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
-
Sharpe, A.H., Wherry, E.J., Ahmed, R. & Freeman, G.J. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat. Immunol. 8, 239-245 (2007).
-
(2007)
Nat. Immunol.
, vol.8
, pp. 239-245
-
-
Sharpe, A.H.1
Wherry, E.J.2
Ahmed, R.3
Freeman, G.J.4
-
24
-
-
41149112957
-
Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection
-
Ha, S.J. et al. Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection. J. Exp. Med. 205, 543-555 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 543-555
-
-
Ha, S.J.1
-
25
-
-
73349126428
-
Taking advantage: High-affnity B cells in the germinal center have lower death rates, but similar rates of division, compared to low-affnity cells
-
Anderson, S.M. et al. Taking advantage: high-affnity B cells in the germinal center have lower death rates, but similar rates of division, compared to low-affnity cells. J. Immunol. 183, 7314-7325 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 7314-7325
-
-
Anderson, S.M.1
-
26
-
-
23844445862
-
Two waves of memory B-cell generation in the primary immune response
-
Inamine, A. et al. Two waves of memory B-cell generation in the primary immune response. Int. Immunol. 17, 581-589 (2005).
-
(2005)
Int. Immunol.
, vol.17
, pp. 581-589
-
-
Inamine, A.1
-
27
-
-
0035099037
-
Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire
-
Takahashi, Y., Ohta, H. & Takemori, T. Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire. Immunity 14, 181-192 (2001).
-
(2001)
Immunity
, vol.14
, pp. 181-192
-
-
Takahashi, Y.1
Ohta, H.2
Takemori, T.3
-
28
-
-
42949103482
-
Improved methods for detecting selection by mutation analysis of Ig v region sequences
-
Hershberg, U., Uduman, M., Shlomchik, M.J. & Kleinstein, S.H. Improved methods for detecting selection by mutation analysis of Ig V region sequences. Int. Immunol. 20, 683-694 (2008).
-
(2008)
Int. Immunol.
, vol.20
, pp. 683-694
-
-
Hershberg, U.1
Uduman, M.2
Shlomchik, M.J.3
Kleinstein, S.H.4
-
29
-
-
61949131896
-
Follicular helper T cells: Lineage and location
-
Fazilleau, N., Mark, L., McHeyzer-Williams, L.J. & McHeyzer-Williams, M.G. Follicular helper T cells: lineage and location. Immunity 30, 324-335 (2009).
-
(2009)
Immunity
, vol.30
, pp. 324-335
-
-
Fazilleau, N.1
Mark, L.2
McHeyzer-Williams, L.J.3
McHeyzer-Williams, M.G.4
-
30
-
-
0030888193
-
B cell development under the condition of allelic inclusion
-
Sonoda, E. et al. B cell development under the condition of allelic inclusion. Immunity 6, 225-233 (1997).
-
(1997)
Immunity
, vol.6
, pp. 225-233
-
-
Sonoda, E.1
-
31
-
-
0027505015
-
A rheumatoid factor transgenic mouse model of autoantibody regulation
-
Shlomchik, M.J., Zharhary, D., Saunders, T., Camper, S.A. & Weigert, M.G. A rheumatoid factor transgenic mouse model of autoantibody regulation. Int. Immunol. 5, 1329-1341 (1993).
-
(1993)
Int. Immunol.
, vol.5
, pp. 1329-1341
-
-
Shlomchik, M.J.1
Zharhary, D.2
Saunders, T.3
Camper, S.A.4
Weigert, M.G.5
-
32
-
-
14244257818
-
Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization
-
Blink, E.J. et al. Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization. J. Exp. Med. 201, 545-554 (2005).
-
(2005)
J. Exp. Med.
, vol.201
, pp. 545-554
-
-
Blink, E.J.1
-
33
-
-
0037159687
-
A critical role for IL-21 in regulating immunoglobulin production
-
Ozaki, K. et al. A critical role for IL-21 in regulating immunoglobulin production. Science 298, 1630-1634 (2002).
-
(2002)
Science
, vol.298
, pp. 1630-1634
-
-
Ozaki, K.1
-
34
-
-
58149191881
-
The common γ-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands
-
Kinter, A.L. et al. The common γ-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands. J. Immunol. 181, 6738-6746 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 6738-6746
-
-
Kinter, A.L.1
-
35
-
-
65549114338
-
+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells
-
+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells. J. Exp. Med. 206, 1001-1007 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1001-1007
-
-
King, I.L.1
Mohrs, M.2
-
36
-
-
77149142640
-
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism
-
Zotos, D. et al. IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism. J. Exp. Med. 207, 365-378 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 365-378
-
-
Zotos, D.1
-
37
-
-
77149122105
-
IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses
-
Linterman, M.A. et al. IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses. J. Exp. Med. 207, 353-363 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 353-363
-
-
Linterman, M.A.1
-
38
-
-
76149139419
-
B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans
-
Avery, D.T. et al. B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans. J. Exp. Med. 207, 155-171 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 155-171
-
-
Avery, D.T.1
-
39
-
-
0347756722
-
Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation
-
Hasbold, J., Corcoran, L.M., Tarlinton, D.M., Tangye, S.G. & Hodgkin, P.D. Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation. Nat. Immunol. 5, 55-63 (2004).
-
(2004)
Nat. Immunol.
, vol.5
, pp. 55-63
-
-
Hasbold, J.1
Corcoran, L.M.2
Tarlinton, D.M.3
Tangye, S.G.4
Hodgkin, P.D.5
-
40
-
-
0031787366
-
The logic of intercellular communication in the immune system
-
Hodgkin, P.D., Rush, J., Gett, A.V., Bartell, G. & Hasbold, J. The logic of intercellular communication in the immune system. Immunol. Cell Biol. 76, 448-453 (1998).
-
(1998)
Immunol. Cell Biol.
, vol.76
, pp. 448-453
-
-
Hodgkin, P.D.1
Rush, J.2
Gett, A.V.3
Bartell, G.4
Hasbold, J.5
-
41
-
-
73949088551
-
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
-
Francisco, L.M. et al. PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. J. Exp. Med. 206, 3015-3029 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 3015-3029
-
-
Francisco, L.M.1
-
42
-
-
0038491416
-
+ T cells independent of the PD-1 receptor
-
+ T cells independent of the PD-1 receptor. J. Exp. Med. 198, 31-38 (2003).
-
(2003)
J. Exp. Med.
, vol.198
, pp. 31-38
-
-
Shin, T.1
-
43
-
-
33645846313
-
Tissue expression of PD-L1 mediates peripheral T cell tolerance
-
Keir, M.E. et al. Tissue expression of PD-L1 mediates peripheral T cell tolerance. J. Exp. Med. 203, 883-895 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 883-895
-
-
Keir, M.E.1
-
44
-
-
0031685190
-
Immunological studies on PD-1 defcient mice: Implication of PD-1 as a negative regulator for B cell responses
-
Nishimura, H., Minato, N., Nakano, T. & Honjo, T. Immunological studies on PD-1 defcient mice: implication of PD-1 as a negative regulator for B cell responses. Int. Immunol. 10, 1563-1572 (1998).
-
(1998)
Int. Immunol.
, vol.10
, pp. 1563-1572
-
-
Nishimura, H.1
Minato, N.2
Nakano, T.3
Honjo, T.4
-
45
-
-
38449115210
-
PD-1 regulates self-reactive CD8+ T cell responses to antigen in lymph nodes and tissues
-
Keir, M.E., Freeman, G.J. & Sharpe, A.H. PD-1 regulates self-reactive CD8+ T cell responses to antigen in lymph nodes and tissues. J. Immunol. 179, 5064-5070 (2007).
-
(2007)
J. Immunol.
, vol.179
, pp. 5064-5070
-
-
Keir, M.E.1
Freeman, G.J.2
Sharpe, A.H.3
-
46
-
-
0029854905
-
A disease-related rheumatoid factor autoantibody is not tolerized in a normal mouse: Implications for the origins of autoantibodies in autoimmune disease
-
Hannum, L.G., Ni, D., Haberman, A.M., Weigert, M.G. & Shlomchik, M.J. A disease-related rheumatoid factor autoantibody is not tolerized in a normal mouse: implications for the origins of autoantibodies in autoimmune disease. J. Exp. Med. 184, 1269-1278 (1996).
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1269-1278
-
-
Hannum, L.G.1
Ni, D.2
Haberman, A.M.3
Weigert, M.G.4
Shlomchik, M.J.5
-
47
-
-
0029164869
-
Light chain replacement: A new model for antibody gene rearrangement
-
Prak, E.L. & Weigert, M. Light chain replacement: a new model for antibody gene rearrangement. J. Exp. Med. 182, 541-548 (1995).
-
(1995)
J. Exp. Med.
, vol.182
, pp. 541-548
-
-
Prak, E.L.1
Weigert, M.2
-
48
-
-
0027305425
-
H locus
-
H locus. Int. Immunol. 5, 647-656 (1993).
-
(1993)
Int. Immunol.
, vol.5
, pp. 647-656
-
-
Chen, J.1
-
49
-
-
0034596892
-
Germinal center initiation, variable gene region hypermutation, and mutant B cell selection without detectable immune complexes on follicular dendritic cells
-
Hannum, L.G., Haberman, A.M., Anderson, S.M. & Shlomchik, M.J. Germinal center initiation, variable gene region hypermutation, and mutant B cell selection without detectable immune complexes on follicular dendritic cells. J. Exp. Med. 192, 931-942 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 931-942
-
-
Hannum, L.G.1
Haberman, A.M.2
Anderson, S.M.3
Shlomchik, M.J.4
-
50
-
-
34548383012
-
New markers for murine memory B cells that defne mutated and unmutated subsets
-
Anderson, S.M., Tomayko, M.M., Ahuja, A., Haberman, A.M. & Shlomchik, M.J. New markers for murine memory B cells that defne mutated and unmutated subsets. J. Exp. Med. 204, 2103-2114 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2103-2114
-
-
Anderson, S.M.1
Tomayko, M.M.2
Ahuja, A.3
Haberman, A.M.4
Shlomchik, M.J.5
|