IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Eto, Danelle ^a   Lao, Christopher ^a   DiToro, Daniel ^a,b   Barnett, Burton ^a,c   Escobar, Tania C ^a   Kageyama, Robin ^a   Yusuf, Isharat ^a,d   Crotty, Shane ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d MEDIMMUNE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERLEUKIN 6; CHEMOKINE RECEPTOR CXCR5; IMMUNOGLOBULIN G; INTERLEUKIN 21; INTERLEUKIN 6; MONOCLONAL ANTIBODY; PROTEIN BCL 6; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; INTERLEUKIN DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GERMINAL CENTER; HELPER CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTIC CHORIOMENINGITIS; NONHUMAN; PROTEIN EXPRESSION; VIRUS NEUTRALIZATION; ANIMAL; B LYMPHOCYTE; BIOSYNTHESIS; CELL DIFFERENTIATION; CYTOLOGY; HUMAN; IMMUNITY; IMMUNOLOGY; METABOLISM; MOUSE; PLASMA CELL;

LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MUS;

ANIMALS; B-LYMPHOCYTES; CELL DIFFERENTIATION; GERMINAL CENTER; HUMANS; IMMUNITY; INTERLEUKIN-6; INTERLEUKINS; LYMPHOCYTE ACTIVATION; MICE; PLASMA CELLS; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 79952637807     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017739     Document Type: Article

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