Diabetes genes identified by genome-wide association studies are regulated in mice by nutritional factors in metabolically relevant tissues and by glucose concentrations in islets

BMC Genetics

Volumn 14, Issue , 2013, Pages

  Ho, Maggie M ^a   Yoganathan, Piriya ^a   Chu, Kwan Y ^a   Karunakaran, Subashini ^a   Johnson, James D ^a   Clee, Susanne M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Feeding and fasting; Gene expression; Genome wide association; Glucotoxicity; High fat diet; Mice; Pancreatic islets; Type 2 diabetes

Indexed keywords

GLUCOSE;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; GENE EXPRESSION; GENETIC ASSOCIATION; HYPOTHALAMUS; LIPID DIET; LIVER; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET;

ADIPOSE TISSUE; ANIMALS; BRAIN; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIET; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; INTRONS; ISLETS OF LANGERHANS; LIVER; MICE;

ANIMALIA; MUS; THADA;

EID: 84874119506     PISSN: None     EISSN: 14712156     Source Type: Journal    
DOI: 10.1186/1471-2156-14-10     Document Type: Article

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