메뉴 건너뛰기




Volumn 7, Issue 2, 2011, Pages

The architecture of gene regulatory variation across multiple human tissues: The muTHER study

(35)  Nica, Alexandra C a,b   Parts, Leopold a   Glass, Daniel c   Nisbet, James a   Barrett, Amy d   Sekowska, Magdalena a   Travers, Mary d   Potter, Simon a   Grundberg, Elin a,c   Small, Kerrin a,c   Hedman, Åsa K d   Bataille, Veronique c   Bell, Jordana c,d   Surdulescu, Gabriela c   Dimas, Antigone S b,d   Ingle, Catherine a   Nestle, Frank O c   Meglio, Paola c   Min, Josine L d   Wilk, Alicja a   more..


Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BODY FAT; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENETIC REGULATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOBLASTOID CELL LINE; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN; TISSUE SPECIFICITY; TWINS; ADIPOSE TISSUE; ANTIBODY SPECIFICITY; CELL CULTURE; CELL LINE; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; PHENOTYPE; REGULATOR GENE; STATISTICAL ANALYSIS;

EID: 79952256739     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002003     Document Type: Article
Times cited : (340)

References (27)
  • 1
    • 77950458649 scopus 로고    scopus 로고
    • Transcriptome genetics using second generation sequencing in a Caucasian population
    • Montgomery SB, Sammeth M, Gutierrez-Arcelus M, Lach RP, Ingle C, et al. (2010) Transcriptome genetics using second generation sequencing in a Caucasian population. Nature 464: 773-777.
    • (2010) Nature , vol.464 , pp. 773-777
    • Montgomery, S.B.1    Sammeth, M.2    Gutierrez-Arcelus, M.3    Lach, R.P.4    Ingle, C.5
  • 2
    • 77950460661 scopus 로고    scopus 로고
    • Understanding mechanisms underlying human gene expression variation with RNA sequencing
    • Pickrell JK, Marioni JC, Pai AA, Degner JF, Engelhardt BE, et al. (2010) Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature 464: 768-772.
    • (2010) Nature , vol.464 , pp. 768-772
    • Pickrell, J.K.1    Marioni, J.C.2    Pai, A.A.3    Degner, J.F.4    Engelhardt, B.E.5
  • 3
    • 27644482314 scopus 로고    scopus 로고
    • Mapping determinants of human gene expression by regional and genome-wide association
    • Cheung VG, Spielman RS, Ewens KG, Weber TM, Morley M, et al. (2005) Mapping determinants of human gene expression by regional and genome-wide association. Nature 437: 1365-1369.
    • (2005) Nature , vol.437 , pp. 1365-1369
    • Cheung, V.G.1    Spielman, R.S.2    Ewens, K.G.3    Weber, T.M.4    Morley, M.5
  • 4
    • 55449112185 scopus 로고    scopus 로고
    • Genome-wide associations of gene expression variation in humans
    • doi:10.1371/journal.pgen.0010078
    • Stranger BE, Forrest MS, Clark AG, Minichiello MJ, Deutsch S, et al. (2005) Genome-wide associations of gene expression variation in humans. PLoS Genet 1: e78 doi:10.1371/journal.pgen.0010078.
    • (2005) PLoS Genet , vol.1
    • Stranger, B.E.1    Forrest, M.S.2    Clark, A.G.3    Minichiello, M.J.4    Deutsch, S.5
  • 6
    • 33846978695 scopus 로고    scopus 로고
    • Relative impact of nucleotide and copy number variation on gene expression phenotypes
    • Stranger BE, Forrest MS, Dunning M, Ingle CE, Beazley C, et al. (2007) Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science 315: 848-853.
    • (2007) Science , vol.315 , pp. 848-853
    • Stranger, B.E.1    Forrest, M.S.2    Dunning, M.3    Ingle, C.E.4    Beazley, C.5
  • 7
    • 69949176863 scopus 로고    scopus 로고
    • Common regulatory variation impacts gene expression in a cell type-dependent manner
    • Dimas AS, Deutsch S, Stranger BE, Montgomery SB, Borel C, et al. (2009) Common regulatory variation impacts gene expression in a cell type-dependent manner. Science 325: 1246-1250.
    • (2009) Science , vol.325 , pp. 1246-1250
    • Dimas, A.S.1    Deutsch, S.2    Stranger, B.E.3    Montgomery, S.B.4    Borel, C.5
  • 10
    • 45149108420 scopus 로고    scopus 로고
    • Mapping the genetic architecture of gene expression in human liver
    • doi:10.1371/journal.pbio.0060107
    • Schadt EE, Molony C, Chudin E, Hao K, Yang X, et al. (2008) Mapping the genetic architecture of gene expression in human liver. PLoS Biol 6: e107 doi:10.1371/journal.pbio.0060107.
    • (2008) PLoS Biol , vol.6
    • Schadt, E.E.1    Molony, C.2    Chudin, E.3    Hao, K.4    Yang, X.5
  • 11
    • 34548719076 scopus 로고    scopus 로고
    • Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes
    • Goring HH, Curran JE, Johnson MP, Dyer TD, Charlesworth J, et al. (2007) Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nat Genet 39: 1208-1216.
    • (2007) Nat Genet , vol.39 , pp. 1208-1216
    • Goring, H.H.1    Curran, J.E.2    Johnson, M.P.3    Dyer, T.D.4    Charlesworth, J.5
  • 12
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661-678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 13
    • 42649086788 scopus 로고    scopus 로고
    • From gene expression to disease risk
    • Dermitzakis ET, (2008) From gene expression to disease risk. Nat Genet 40: 492-493.
    • (2008) Nat Genet , vol.40 , pp. 492-493
    • Dermitzakis, E.T.1
  • 14
    • 40749105508 scopus 로고    scopus 로고
    • Variations in DNA elucidate molecular networks that cause disease
    • Chen Y, Zhu J, Lum PY, Yang X, Pinto S, et al. (2008) Variations in DNA elucidate molecular networks that cause disease. Nature 452: 429-435.
    • (2008) Nature , vol.452 , pp. 429-435
    • Chen, Y.1    Zhu, J.2    Lum, P.Y.3    Yang, X.4    Pinto, S.5
  • 15
    • 34547216747 scopus 로고    scopus 로고
    • Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
    • Moffatt MF, Kabesch M, Liang L, Dixon AL, Strachan D, et al. (2007) Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448: 470-473.
    • (2007) Nature , vol.448 , pp. 470-473
    • Moffatt, M.F.1    Kabesch, M.2    Liang, L.3    Dixon, A.L.4    Strachan, D.5
  • 16
    • 50449091647 scopus 로고    scopus 로고
    • Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
    • McCarroll SA, Huett A, Kuballa P, Chilewski SD, Landry A, et al. (2008) Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet 40: 1107-1112.
    • (2008) Nat Genet , vol.40 , pp. 1107-1112
    • McCarroll, S.A.1    Huett, A.2    Kuballa, P.3    Chilewski, S.D.4    Landry, A.5
  • 17
    • 77952367694 scopus 로고    scopus 로고
    • Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations
    • doi:10.1371/journal.pgen.1000895
    • Nica AC, Montgomery SB, Dimas AS, Stranger BE, Beazley C, et al. (2010) Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations. PLoS Genet 6: e1000895 doi:10.1371/journal.pgen.1000895.
    • (2010) PLoS Genet , vol.6
    • Nica, A.C.1    Montgomery, S.B.2    Dimas, A.S.3    Stranger, B.E.4    Beazley, C.5
  • 18
    • 77951439152 scopus 로고    scopus 로고
    • Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS
    • doi:10.1371/journal.pgen.1000888
    • Nicolae DL, Gamazon E, Zhang W, Duan S, Dolan ME, et al. (2010) Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genet 6: e1000888 doi:10.1371/journal.pgen.1000888.
    • (2010) PLoS Genet , vol.6
    • Nicolae, D.L.1    Gamazon, E.2    Zhang, W.3    Duan, S.4    Dolan, M.E.5
  • 19
    • 44349142294 scopus 로고    scopus 로고
    • Common variants near MC4R are associated with fat mass, weight and risk of obesity
    • Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, et al. (2008) Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 40: 768-775.
    • (2008) Nat Genet , vol.40 , pp. 768-775
    • Loos, R.J.1    Lindgren, C.M.2    Li, S.3    Wheeler, E.4    Zhao, J.H.5
  • 20
    • 77649299348 scopus 로고    scopus 로고
    • An atlas of combinatorial transcriptional regulation in mouse and man
    • Ravasi T, Suzuki H, Cannistraci CV, Katayama S, Bajic VB, et al. (2010) An atlas of combinatorial transcriptional regulation in mouse and man. Cell 140: 744-752.
    • (2010) Cell , vol.140 , pp. 744-752
    • Ravasi, T.1    Suzuki, H.2    Cannistraci, C.V.3    Katayama, S.4    Bajic, V.B.5
  • 21
    • 77950339092 scopus 로고    scopus 로고
    • Integrating Pathway Analysis and Genetics of Gene Expression for Genome-wide Association Studies
    • Zhong H, Yang X, Kaplan LM, Molony C, Schadt EE, (2010) Integrating Pathway Analysis and Genetics of Gene Expression for Genome-wide Association Studies. Am J Hum Genet.
    • (2010) Am J Hum Genet
    • Zhong, H.1    Yang, X.2    Kaplan, L.M.3    Molony, C.4    Schadt, E.E.5
  • 23
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey JD, Tibshirani R, (2003) Statistical significance for genomewide studies. Proc Natl Acad Sci U S A 100: 9440-9445.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 24
    • 73349126396 scopus 로고    scopus 로고
    • Geographical genomics of human leukocyte gene expression variation in southern Morocco
    • Idaghdour Y, Czika W, Shianna KV, Lee SH, Visscher PM, et al. (2010) Geographical genomics of human leukocyte gene expression variation in southern Morocco. Nat Genet 42: 62-67.
    • (2010) Nat Genet , vol.42 , pp. 62-67
    • Idaghdour, Y.1    Czika, W.2    Shianna, K.V.3    Lee, S.H.4    Visscher, P.M.5
  • 25
    • 77955505742 scopus 로고    scopus 로고
    • A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies
    • doi:10.1371/journal.pcbi.1000770
    • Stegle O, Parts L, Durbin R, Winn J, (2010) A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies. PLoS Comput Biol 6: e1000770 doi:10.1371/journal.pcbi.1000770.
    • (2010) PLoS Comput Biol , vol.6
    • Stegle, O.1    Parts, L.2    Durbin, R.3    Winn, J.4
  • 26
    • 35748941336 scopus 로고    scopus 로고
    • A genotype calling algorithm for the Illumina BeadArray platform
    • Teo YY, Inouye M, Small KS, Gwilliam R, Deloukas P, et al. (2007) A genotype calling algorithm for the Illumina BeadArray platform. Bioinformatics 23: 2741-2746.
    • (2007) Bioinformatics , vol.23 , pp. 2741-2746
    • Teo, Y.Y.1    Inouye, M.2    Small, K.S.3    Gwilliam, R.4    Deloukas, P.5
  • 27
    • 2142773942 scopus 로고    scopus 로고
    • The fine-scale structure of recombination rate variation in the human genome
    • McVean GA, Myers SR, Hunt S, Deloukas P, Bentley DR, et al. (2004) The fine-scale structure of recombination rate variation in the human genome. Science 304: 581-584.
    • (2004) Science , vol.304 , pp. 581-584
    • McVean, G.A.1    Myers, S.R.2    Hunt, S.3    Deloukas, P.4    Bentley, D.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.