Finite and infinite dosing: Difficulties in measurements, evaluations and predictions

Advanced Drug Delivery Reviews

Volumn 65, Issue 2, 2013, Pages 278-294

  Selzer, Dominik ^a   Abdel Mottaleb, Mona M A ^b   Hahn, Tsambika ^a   Schaefer, Ulrich F ^a   Neumann, Dirk ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b AIN SHAMS UNIVERSITY   (Egypt)

Author keywords

Concentration depth profile; In vitro; In vivo; Penetration; Permeation; Tape stripping

Indexed keywords

CONCENTRATION-DEPTH PROFILE; IN-VITRO; IN-VIVO; PENETRATION; TAPE STRIPPING;

BIOCHEMISTRY; PERMEATION; SKIN;

EXPERIMENTS;

ANTIINFLAMMATORY AGENT; BETAMETHASONE VALERATE; ESTRADIOL; FLUFENAMIC ACID; FLUOROURACIL; GENTAMICIN; MACROGOL 400; PARAFFIN; POLYOXYETHYLENE OLEYL ETHER; SUNSCREEN; XENOBIOTIC AGENT;

AQUEOUS SOLUTION; BIOACCUMULATION; BIOEQUIVALENCE; BIOLOGICAL MODEL; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG DOSE; DRUG EXPOSURE; DRUG FORMULATION; DRUG PENETRATION; DRUG RESEARCH; DRUG SCREENING; DRUG SOLUBILITY; DRUG TISSUE LEVEL; DRUG UPTAKE; EMULSION; FINITE DOSE; HUMAN; HYDRATION; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; INFINITE DOSE; LIPOPHILICITY; LIQUID; MATHEMATICAL ANALYSIS; MATHEMATICAL COMPUTING; MATHEMATICAL PARAMETERS; MEASUREMENT; MOLECULAR BIOLOGY; NONHUMAN; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; REVIEW; SKIN PENETRATION; SKIN PERMEABILITY; SKIN STRUCTURE; STRATUM CORNEUM; VALIDATION STUDY;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; HUMANS; MODELS, THEORETICAL; PERMEABILITY; SKIN; SKIN ABSORPTION; XENOBIOTICS;

EID: 84873521769     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2012.06.010     Document Type: Review

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