In vitro-in vivo correlation in man of a topically applied local anesthetic agent using numerical convolution and deconvolution

Journal of Pharmaceutical Sciences

Volumn 92, Issue 2, 2003, Pages 398-406

  Welin Berger, Katayoun ^a   Neelissen, Jan A M ^a   Emanuelsson, Britt Marie ^a   Björnsson, Marcus A ^a   Gjellan, Kirsti ^a  

^a ASTRAZENECA R AND D   (Sweden)

Author keywords

Convolution; Deconvolution; In vitro; In vivo; Local anesthetic agent

Indexed keywords

COCONUT OIL; ISOPROPYL METHYL[2 (3 PROPOXYPHENYL)ETHYL]AMINE; LOCAL ANESTHETIC AGENT; POLOXAMER; POLYGLYCEROL POLYRICINOLEATE; RICINOLEIC ACID; RYLO; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; BOLUS INJECTION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG FORMULATION; DRUG PENETRATION; EMULSION; FEMALE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; LOCAL ANESTHESIA; NORMAL HUMAN; SIMULATION; SKIN;

EID: 0037309688     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10203     Document Type: Article

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