Development of an in vivo animal model for skin penetration in hairless rats assessed by mass balance

Skin Pharmacology and Applied Skin Physiology

Volumn 15, Issue 6, 2002, Pages 414-424

  Simonsen, Lene ^a,b   Petersen, Mads B ^a   Benfeldt, Eva ^b   Serup, Jørgen ^a  

^a LEO PHARMA A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Animal model; Butyl salicylate; Lateral diffusion; Mass balance; Percutaneous absorption; Salicylic acid; Tape stripping; Topical application

Indexed keywords

SALICYLIC ACID; SALICYLIC ACID DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVICE; DIFFUSION; DRUG FORMULATION; FEMALE; HISTOLOGY; MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; RADIOACTIVITY; RAT; SKIN; SKIN ABSORPTION; SKIN BIOPSY; SKIN PENETRATION; SKIN SURFACE; SKIN WATER LOSS; STRATUM CORNEUM; URINARY EXCRETION;

ADMINISTRATION, TOPICAL; ANIMALS; CARBON RADIOISOTOPES; DRUG EVALUATION, PRECLINICAL; EPIDERMIS; FEMALE; MODELS, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; SALICYLIC ACID; SCINTILLATION COUNTING; SKIN ABSORPTION;

EID: 0036906877     PISSN: 14222868     EISSN: None     Source Type: Journal    
DOI: 10.1159/000066455     Document Type: Article

References (16)

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