New in vitro dermal absorption database and the prediction of dermal absorption under finite conditions for risk assessment purposes

Regulatory Toxicology and Pharmacology

Volumn 57, Issue 2-3, 2010, Pages 200-209

  Buist, Harrie E ^a   van Burgsteden, Johan A ^a   Freidig, Andreas P ^a   Maas, Wilfred J M ^a   van de Sandt, Johannes J M ^a  

^a TNO   (Netherlands)

Author keywords

Dermal absorption; Epidermal membranes; Human; In vitro experiments; Kp; Permeability coefficient; QSAR; Risk assessment; Skin; Stratum corneum water partition coefficient

Indexed keywords

2,4 DICHLOROPHENOL; ACETIC ACID; BENZOIC ACID; CORTISONE; DECANOL; ETACRYNIC ACID; LINOLENIC ACID; OLEIC ACID; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PROPYL PARABEN; SALICYLIC ACID; TESTOSTERONE;

ADULT; ARTICLE; CONTROLLED STUDY; DATA BASE; FEMALE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MATHEMATICAL MODEL; PREDICTION; PRIORITY JOURNAL; RISK ASSESSMENT; SKIN ABSORPTION; TOXICOLOGY;

ADULT; DATABASES, FACTUAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HORMONES; HUMANS; LIPIDS; MIDDLE AGED; MODELS, BIOLOGICAL; ORGANIC CHEMICALS; PROGNOSIS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RISK ASSESSMENT; SKIN; SKIN ABSORPTION;

EID: 77953342351     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2010.02.008     Document Type: Article

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