New insights into skin structure: Scratching the surface

Advanced Drug Delivery Reviews

Volumn 54, Issue SUPPL., 2002, Pages S3-

  Menon, Gopinathan K ^a  

^a Avon Products Inc   (United States)

Author keywords

Lamellar bodies; Permeability barrier; Smart materials; Stratum corneum; Transdermal delivery systems; Transepidermal water loss; Ultrastructure

Indexed keywords

ABSORPTION; BIOLOGICAL MEMBRANES; BIOPOLYMERS; EXTRAPOLATION; SKIN;

TRANSDERMAL SYSTEMS (TDS);

DERMATOLOGY;

BIOPOLYMER;

CADAVER; COMPOSITE MATERIAL; CONFERENCE PAPER; DRUG DELIVERY SYSTEM; HISTOLOGY; HUMAN; NONHUMAN; PRIORITY JOURNAL; SKIN ABSORPTION; SKIN FUNCTION; SKIN STRUCTURE; SKIN SURFACE; STRATUM CORNEUM;

EID: 0036852419     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(02)00121-7     Document Type: Conference Paper

References (36)

1. Chuong C.M., Nickloff B.J., Elias P.M., Goldsmith L.A., Macher E., Maderson P.F.A., Sundberg J.P., Tagami H., Plonka P.M., Thestrup-Pedersen K., Bernard B.A., Schroder J.M., Dotto P., Chang M.H.C., Williams M.L., Feingold K.R., King L.E., Kligman A.M., Rees J.L., Christophers E. What is the 'true' function of skin? Exp. Dermatol. 11:2002;159-187.
2. Elias P.M., Cullander C., Mauro T., Rassner U., Komuves L., Brown B.E., Menon G.K. The secretory granular cell: the outermost granular cell as a specialized secretory cell. J. Invest. Dermatol. Symp. Proc. 3:1998;87-100.
3. Menon G.K., Ghadially R. Morphology of lipid alterations in the epidermis: a review. Microsc. Res. Tech. 37:1997;180-192.
4. Elias P.M., Menon G.K. Structural and biochemical correlates of the epidermal permeability barrier. Elias P.M. Advances in Lipid Research. Vol. 24:1991;1-26 Academic Press, New York.
5. Hennings H., Michael D., Cheng C., Steinert P., Holbrook K., Yuspa S.H. Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell. 19:1980;245-254.
6. Menon G.K., Grayson S., Elias P.M. Ionic calcium reservoirs in mammalian epidermis: ultrastructural localization with ion capture cytochemistry. J. Invest. Dermatol. 84:1985;508-512.
7. Holbrook K. Ultrastructure of the epidermis. Leigh I.M., Lane B.E., Watt F.M. The Keratinocyte Handbook. 1994;3-39 Cambridge University Press, Oxford.
8. Williams M.L., Elias P.M. From basket weave to barrier: unifying concepts for the pathogenesis of disorders of cornification. Arch. Dermatol. 129:1993;626-628.
9. Rawlings A.V., Scott I.R., Harding C.R., Bowser P.A. Stratum corneum moisturization at the molecular level. J. Invest. Dermatol. 103:1994;731-740.
10. Grayson S., Elias P.M. Isolation and lipid biochemical characterization of stratum corneum membrane complexes: implications for the cutaneous permeability barrier. J. Invest. Dermatol. 78:1982;128-135.
11. Wertz P.N., Downing D.L. Epidermal lipids. Goldsmith L.A. Physiology, Biochemistry and Molecular Biology of the Skin. 1991;205-236 Oxford University Press, New York.
12. Bouwstra J.A., Dubbelaar F.E.R., Gooris G.S., Weerheim A.M., Ponec M. The role of ceramide composition in the lipid organization of the skin barrier. Biochim. Biophys. Acta. 1419:1999;127-136.
13. Menon G.K., Brandsma J., Schwartz P. Gene gun and the human skin: ultrastructural study of the distribution of gold particles in the epidermis. J. Invest. Dermatol. 110:1997;637. Abstract.
14. Friberg S.E., Kayali I., Beckerman W., Rhein L.D., Simion A. Water permeation of reaggregated stratum corneum with model lipids. J. Invest. Dermatol. 94:1990;377-380.
15. Forslind B. A domain mosaic model of the skin barrier. Acta Dermatol. Venereol. 74:1994;1-6.
16. Kitson N., Thewalt J., Lafleur M., Bloom M.A. A model membrane approach to the epidermal permeability barrier. Biochemistry. 33:1994;6707-6715.
17. Norlen L. Barrier structure and function: the single gel phase model. J. Invest. Dermatol. 117:2001;830-836.
18. Bouwstra J.A., Pilgram G.S.K., Ponec M. Does the single gel phase exist in stratum corneum? J. Invest. Dermatol. 118:2002;897-899. Letters to the Editor.
19. Norlen L. Reply - letters to the Editor. J. Invest. Dermatol. 118:2002;889-901.
20. Flynn G.L. Mechanism of percutaneous absorption from physiochemical evidence. Branaugh R.L., Maibach H.I. Percutaneous Absorption. 1989;27-51 Decker, New York.
21. Menon G.K., Elias P.M. Morphological basis for a pore-pathway in mammalian stratum corneum. Skin Pharmacol. 10:1997;235-246.
22. Charles J., Paul B.O. Reducing costs by using duplex stainless steels. Chem. Process. 1996;40.
23. Hoath S.B., Visscher M., Heaton C., Neale H. Skin science and the future of dermatology. J. Cutan. Med. Surg. 3:1998;2-8.
24. Newnham R.E., Ruschau G.R. Smart electroceramics. Am. Ceram. Bull. 75:1996;51-61.
25. Behne M., Uchida Y., Seki T., deMontellano P.P., Elias P.M., Holleran W.M. Omega hydroxyceramides are required for corneocyte envelope formation and normal epidermal permeability barrier function. J. Invest. Dermatol. 114:2000;185-192.
26. Cork M., Murphy R., Carr J., Bavik C., Ward S.J., Tazi-Ahnini R. The increasing prevalence of atopic eczema and environmental trauma to the skin. Ann. Dermatol. Venereol. 2002;1S217. Abstract number WK 1089.
27. Denda M., Tsuchiya T., Hosoi J., Koyama J. Immobilization-induced and crowded environment-induced stress delay barrier recovery in murine skin. Br. J. Dermatol. 138:(5):1998;780-785.
28. P.M. Elias, J. Tsai, C. Thornfeldt, G.K. Menon, K.R. Feingold, Metabolic approach to transdermal delivery, in: E. Hadgraft, R. Guy (Eds.), Transdermal Delivery Systems, 2nd Edition, in press.
29. Warner R.R., Boissy Y.L., Lilly N.A., McKillop K., Marshall J.A., Stone K.J. Water disrupts stratum corneum lipid lamellae: damage is similar to surfactants. J. Invest. Dermatol. 113:1999;960-966.
30. van Hal D.A., Jeremiasse E., Junginger H.E., Spies F., Bouwstra J.A. Structure of fully hydrated human stratum corneum: a freeze-fracture electron microscopy study. J. Invest. Dermatol. 106:1996;89-95.
31. Chilcott R.P., Dalton C.H., Emmanuel A.J., Allen C.E., Bradley S.T. Transepidermal water loss does not correlate with skin barrier function in vitro. J. Invest. Dermatol. 118:2002;871-875.
32. Menon G.K., Grayson S., Brown B.E., Elias P.M. Lipokeratinocytes of the epidermis of a cetacean (Phocaena phocaena): histochemistry, ultrastructure and lipid composition. Cell Tissue Res. 244:1986;385-394.
33. Theile J.J., Weber S.U., Packer L. Sebaceous gland secretion is a major route of vitamin E to skin. J. Invest. Dermatol. 113:1999;1006-1010.
34. Zouboulis C.C., Seltmann H., Hiroi N., Chen W., Young M., Oeff M., Scherbaum W.A., Orfanos C.E., McCann S.M., Bornstein S.R. Corticotropin-releasing hormone: an autocrine hormone that promotes lipogenesis in human sebocytes. Proc. Natl. Acad. Sci. USA. 99:2002;7148-7153.
35. Chronnel C.M., Ghali L.R., Ali R.S., Quinn A.G., Holland D.B., Bull J.J., Cunliff C., McKay I.A., Philpott M.P., Muller-Rover S. Human beta defensin-1 and -2 expression in human pilosebaceous units: upregulation in acne vulgaris lesions. J. Invest. Dermatol. 117:2001;1120-1125.
36. Murakami M. Sweat: an innate defense barrier that contains natural antibiotic peptides. Annual Meeting of the Society for Investigative Dermatology, Los Angeles, CA. 2002;. Abstract number 547.