Interactions of skin thickness and physicochemical properties of test compounds in percutaneous penetration studies

International Archives of Occupational and Environmental Health

Volumn 79, Issue 5, 2006, Pages 405-413

  Wilkinson, Simon C ^a,d   Maas, Wilfred J M ^b   Nielsen, Jesper Bo ^c   Greaves, Laura C ^a   van de Sandt, Johannes J M ^b   Williams, Faith M ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b TNO   (Netherlands)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

In vitro percutaneous penetration; Lipophilicity; OECD guideline 428

Indexed keywords

2 BUTOXYETHANOL; ALCOHOL; CAFFEINE; PROPOXUR; TESTOSTERONE; WATER;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LIPOPHILICITY; LIQUID SCINTILLATION COUNTING; PHYSICAL CHEMISTRY; SKIN ABSORPTION; SKIN PENETRATION; SKIN PERMEABILITY; SKINFOLD THICKNESS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; VALIDATION PROCESS;

2,4-DICHLOROPHENOXYACETIC ACID; CAFFEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EUROPE; HUMANS; PROPOXUR; SKIN ABSORPTION; SKIN PHYSIOLOGICAL PHENOMENA; SKIN PHYSIOLOGY; TESTOSTERONE;

EID: 33645135971     PISSN: 03400131     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00420-005-0056-5     Document Type: Article

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