Can increasing the viscosity of formulations be used to reduce the human skin penetration of the sunscreen oxybenzone?

Journal of Investigative Dermatology

Volumn 117, Issue 1, 2001, Pages 147-150

  Cross, Sheree E ^c   Jiang, Ruoying ^a   Benson, Heather A E ^b   Roberts, Michael S ^c  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b CURTIN UNIVERSITY   (Australia)

^c NONE

Author keywords

Epidermis; Finite dosing; Hydration; Infinite dosing

Indexed keywords

CARBOMER; CETOMACROGOL; COCONUT OIL; DODICIN; EMULSIFYING AGENT; OXYBENZONE; POLYETHYLENE; SUNSCREEN; THICKENING AGENT; WATER;

ARTICLE; DIFFUSION; DRUG FORMULATION; EMULSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; HYDRATION; PRIORITY JOURNAL; SKIN; SKIN PENETRATION; VISCOSITY;

EID: 0034941295     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2001.01398.x     Document Type: Article

References (10)

1. The effect of occlusion on the epidermal penetration of parabens from a commercial test ointment, acetone and ethanol vehicles
2. Vehicle effects in percutaneous absorption: In-vitro study of influence of solvent power and microscopic viscosity of vehicle on benzocaine release from suspension hydrogels
3. The finite dose technique as a valid in vitro model for the study of percutaneous absorption in man
4. Systemic absorption of sunscreen after topical application
5. High performance liquid chromatographic assay for common sunscreening agents in cosmetic products, bovine serum albumin solution and human plasma
6. In vitro human epidermal and polyethylene membrane penetration and retention of the sunscreen benzophenone-3 from a range of solvents
7. Preparation of isolated sheets of human stratum corneum
8. Studies on the dermal and systemic bioavailability of polycyclic aromatic compounds in high viscosity oil products
9. Water - The most natural skin penetration enhancer
10. Chitosan hydrogel as a base for transdermal delivery of berberine and its evaluation in rat skin