A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas

Journal of Experimental Medicine

Volumn 208, Issue 4, 2011, Pages 689-702

  Agnihotri, Sameer ^a   Wolf, Amparo ^a   Munoz, Diana M ^a   Smith, Christopher J ^a   Gajadhar, Aaron ^a   Restrepo, Andres ^a   Clarke, Ian D ^a   Fuller, Gregory N ^e   Kesari, Santosh ^f   Dirks, Peter B ^a   McGlade, C Jane ^a   Stanford, William L ^b   Aldape, Kenneth ^e   Mischel, Paul S ^g   Hawkins, Cynthia ^c   Guha, Abhijit ^a,d  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 O CYCLOHEXYLMETHYLGUANINE METHYLTRANSFERASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; RAS PROTEIN; TEMOZOLOMIDE; TRANSCRIPTION FACTOR GATA 4; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; ASTROCYTOMA; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE MUTATION; GLIOBLASTOMA; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL; NONHUMAN; OLIGODENDROGLIA; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE;

ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DACARBAZINE; DNA METHYLATION; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; GATA4 TRANSCRIPTION FACTOR; GLIOBLASTOMA; HUMANS; MICE; PROMOTER REGIONS, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 79955717831     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20102099     Document Type: Article

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