Mycothiol: A target for potentiation of rifampin and other antibiotics against Mycobacterium tuberculosis

Expert Review of Anti-Infective Therapy

Volumn 11, Issue 1, 2013, Pages 49-67

  Hernick, Marcy ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

isoniazid; MshA; MshB; MshC; MshD; mycothiol; mycothiol conjugate amidase; mycothiol S transferase; mycothione reductase; rifampin; TB

Indexed keywords

1 DEXTRO MYO INOSITYL 2 ACETAMIDO 2 DEOXY ALPHA DEXTRO GLUCOPYRANOSIDE DEACETYLASE; 1 DEXTRO MYO INOSITYL 2 AMINO 2 DEOXY ALPHA DEXTRO GLUCOPYRANOSIDE LIGASE; AMIKACIN; AMINOSALICYLIC ACID; BACTERIAL ENZYME; CYCLOSERINE; ERYTHROMYCIN; ETHAMBUTOL; ETHIONAMIDE; GATIFLOXACIN; ISONIAZID; KANAMYCIN; LEVOFLOXACIN; MOXIFLOXACIN; MSHA PROTEIN; MSHA2 PROTEIN; MYCOREDOXIN 1; MYCOTHIOL; MYCOTHIOL CONJUGATE AMIDASE; MYCOTHIOL SYNTHASE; MYCOTHIOL TRANSFERASE; MYCOTHIONE REDUCTASE; MYOINOSITOL 1 PHOSPHATE SYNTHASE; PYRAZINAMIDE; RIFABUTIN; RIFAMPICIN; RIFAPENTINE; STREPTOMYCIN; THIOL; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; CONCENTRATION RESPONSE; DETOXIFICATION; DRUG EFFECT; DRUG EFFICACY; DRUG TARGETING; DRUG TREATMENT FAILURE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SYNTHESIS; GEOBACILLUS STEAROTHERMOPHILUS; HUMAN; MYCOBACTERIUM BOVIS; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIMARY HEALTH CARE; REVIEW; TREATMENT DURATION; TUBERCULOSIS;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTITUBERCULAR AGENTS; CYSTEINE; DRUG DELIVERY SYSTEMS; DRUG SYNERGISM; ENZYME INHIBITORS; GLYCOPEPTIDES; HUMANS; INOSITOL; MYCOBACTERIUM TUBERCULOSIS; RIFAMPIN;

EID: 84871988165     PISSN: 14787210     EISSN: 17448336     Source Type: Journal    
DOI: 10.1586/eri.12.152     Document Type: Review

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