Pathogenesis in tuberculosis: Transcriptomic approaches to unraveling virulence mechanisms and finding new drug targets

FEMS Microbiology Reviews

Volumn 36, Issue 2, 2012, Pages 463-485

  Mukhopadhyay, Sangita ^a   Nair, Shiny ^a   Ghosh, Sudip ^b  

^a CENTRE FOR DNA FINGERPRINTING AND DIAGNOSTICS   (India)

^b NATIONAL INSTITUTE OF NUTRITION   (India)

Author keywords

Dendritic cells; Drug targets; Gene expression; Macrophage; Microarray; Mycobacterium tuberculosis; Vaccine candidates

Indexed keywords

BACTERIAL RNA; IRON; ISONIAZID; MYCOLIC ACID; POLYKETIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTOME;

APOPTOSIS; BACTERIAL CELL WALL; BACTERIAL GENE; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; CELLULAR STRESS RESPONSE; DENDRITIC CELL; DNA DAMAGE; DRUG TARGETING; ENZYMATIC DEGRADATION; FATTY ACID METABOLISM; GENE CLUSTER; GENE EXPRESSION; GENE EXPRESSION PROFILING; HOST CELL; HOST PATHOGEN INTERACTION; INTRACELLULAR SPACE; IRON TRANSPORT; MACROPHAGE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATIVE STRESS; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUBERCULOSIS; VIRULENCE;

ANIMALS; ANTI-BACTERIAL AGENTS; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION PROFILING; HUMANS; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS; VIRULENCE;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

EID: 84856727590     PISSN: 01686445     EISSN: 15746976     Source Type: Journal    
DOI: 10.1111/j.1574-6976.2011.00302.x     Document Type: Review

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