Mycothiol-deficient Mycobacterium smegmatis mutants are hypersensitive to alkylating agents, free radicals, and antibiotics

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 11, 2002, Pages 3348-3355

  Rawat, Mamta ^a   Newton, Gerald L ^a   Ko, Mary ^a   Martinez, Gladys J ^a   Fahey, Robert C ^a   Av Gay, Yossef ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; ANTIBIOTIC AGENT; AZITHROMYCIN; ERYTHROMYCIN; ETHAMBUTOL; FREE RADICAL; HYDROGEN PEROXIDE; ISONIAZID; MENADIONE; MYCOTHIOL; NITROFURANTOIN; PENICILLIN G; PLUMBAGIN; PYRAZINAMIDE; RIFAMPICIN; RIFAMYCIN; THIOL DERIVATIVE; UNCLASSIFIED DRUG; VANCOMYCIN;

AMINO ACID SUBSTITUTION; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; BIOSYNTHESIS; CHEMICAL MUTAGENESIS; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE SEQUENCE; GENETIC COMPLEMENTATION; MYCOBACTERIUM SMEGMATIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; STRAIN DIFFERENCE; TOXICITY; TRANSPOSON;

ALKYLATING AGENTS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; CYSTEINE; DISACCHARIDES; DNA TRANSPOSABLE ELEMENTS; DNA, BACTERIAL; FREE RADICALS; GENETIC COMPLEMENTATION TEST; GLYCOPEPTIDES; INOSITOL; LIGASES; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTATION; MYCOBACTERIUM SMEGMATIS; OXIDATIVE STRESS; PHENOTYPE; PYRAZOLES; SULFHYDRYL COMPOUNDS;

EID: 0036840388     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.11.3348-3355.2002     Document Type: Article

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