The substrate-induced conformational change of mycobacterium tuberculosis mycothiol synthase

Journal of Biological Chemistry

Volumn 281, Issue 5, 2006, Pages 2795-2802

  Vetting, Matthew W ^a   Yu, Michael ^a   Rendle, Phillip M ^b   Blanchard, John S ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b CALLAGHAN INNOVATION   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; BACTERIA; CATALYSIS; ENZYMES; SUBSTRATES;

ACETYL TRANSFER; DESACETYLMYCOTHIOL; MYCOBACTERIUM TUBERCULOSIS; MYCOTHIOL SYNTHASE;

DISEASES;

COENZYME A; GLUTAMIC ACID; MYCOTHIOL SYNTHASE; SYNTHETASE; TYROSINE; UNCLASSIFIED DRUG; ACETYL COA 1 D MYO INOSITYL 2 L CYSTEINYLAMIDO 2 DEOXY ALPHA D GLUCOPYRANOSIDE ACETYLTRANSFERASE; ACETYL-COA 1-D-MYO-INOSITYL 2-L-CYSTEINYLAMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE ACETYLTRANSFERASE; ACYLTRANSFERASE; CYSTEINE; DISACCHARIDE; GLYCOPEPTIDE; INOSITOL; MYCOTHIOL; PYRAZOLE DERIVATIVE; THIOL DERIVATIVE;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOSYNTHESIS; CATALYSIS; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; ENZYME STRUCTURE; INFORMATION PROCESSING; KINETICS; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; BINDING SITE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; PROTEIN BINDING; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

MYCOBACTERIUM TUBERCULOSIS;

ACETYLTRANSFERASES; BINDING SITES; COENZYME A; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DISACCHARIDES; GLYCOPEPTIDES; INOSITOL; MYCOBACTERIUM TUBERCULOSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PYRAZOLES; SUBSTRATE SPECIFICITY; SULFHYDRYL COMPOUNDS;

EID: 33646367436     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M510798200     Document Type: Article

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