Crystal structure of inositol 1-phosphate synthase from Mycobacterium tuberculosis, a key enzyme in Phosphatidylinositol Synthesis

Structure

Volumn 10, Issue 3, 2002, Pages 393-402

  Norman, Richard A ^a   McAlister, Mark S B ^b   Murray Rust, Judith ^a,b   Movahedzadeh, Farahnaz ^c   Stoker, Neil G ^c   McDonald, Neil Q ^a,b  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Crystal structure; Inositol; Inositol 1 phosphate synthase; Mycobacterium tuberculosis; Phosphatidylinositol

Indexed keywords

CATION; MYOINOSITOL 1 PHOSPHATE SYNTHASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OLIGOMER; PHOSPHATIDYLINOSITOL; ZINC ION;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIAMINOPIMELIC ACID; INOSITOL PHOSPHATES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; MYO-INOSITOL-1-PHOSPHATE SYNTHASE; NAD; OXIDOREDUCTASES; PHOSPHATIDYLINOSITOLS; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; ZINC;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); EUKARYOTA; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; UNCULTURED ACTINOMYCETE;

EID: 0036118315     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(02)00718-9     Document Type: Article

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