UDP-(5F)-GlcNAc acts as a slow-binding inhibitor of MshA, a retaining glycosyltransferase

Journal of the American Chemical Society

Volumn 132, Issue 19, 2010, Pages 6626-6627

  Frantom, Patrick A ^a,b   Coward, James K ^b   Blanchard, John S ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING INHIBITORS; CELLULAR PATHWAY; CONFORMATIONAL CHANGE; CORYNEBACTERIUM GLUTAMICUM; GLYCOSYL TRANSFERASE; INHIBITION MECHANISMS; KINETIC DATA; OXOCARBENIUM; POTENT INHIBITION; SINGLE-STEP; TRANSITION STATE STRUCTURE; TWO-STEP INHIBITION;

CATALYSTS; ENZYMES; INTERNET PROTOCOLS;

ENZYME INHIBITION;

GLYCOSYLTRANSFERASE; GLYCOSYLTRANSFERASE INHIBITOR; GLYCOSYLTRANSFERASE MSHA; N ACETYLGLUCOSAMINE; SUGAR NUCLEOTIDE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE;

ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME STRUCTURE; NONHUMAN; STRUCTURE ANALYSIS;

CORYNEBACTERIUM GLUTAMICUM; ENZYME INHIBITORS; GLYCOSYLTRANSFERASES; KINETICS; PROTEIN BINDING; URIDINE DIPHOSPHATE N-ACETYLGLUCOSAMINE;

EID: 77952396239     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja101231a     Document Type: Article

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