Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis

Molecular Microbiology

Volumn 69, Issue 5, 2008, Pages 1316-1329

  Vilchèze, Catherine ^a   Av Gay, Yossef ^b   Attarian, Rodgoun ^b   Liu, Zhen ^c   Hazbón, Manzour H ^d,e   Colangeli, Roberto ^d   Chen, Bing ^a   Liu, Weijun ^a   Alland, David ^d   Sacchettini, James C ^c   Jacobs Jr , William R ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c TEXAS A AND M UNIVERSITY   (United States)

^d RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^e WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHIONAMIDE; MYCOTHIOL; THIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM MUTANT; CONTROLLED STUDY; FRAMESHIFT MUTATION; GENE DELETION; GENE MUTATION; IMMUNOCOMPETENCE; MISSENSE MUTATION; MOUSE; MSHA GENE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE;

AMINO ACID SEQUENCE; ANIMALS; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; CATALASE; CORYNEBACTERIUM GLUTAMICUM; CYSTEINE; DRUG RESISTANCE, BACTERIAL; ETHIONAMIDE; GLYCOPEPTIDES; GLYCOSYLTRANSFERASES; HUMANS; INOSITOL; ISONIAZID; MICE; MICE, INBRED C57BL; MICE, SCID; MICROBIAL SENSITIVITY TESTS; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM INFECTIONS; MYCOBACTERIUM TUBERCULOSIS; SEQUENCE ALIGNMENT; SEQUENCE DELETION; TUBERCULOSIS, MULTIDRUG-RESISTANT;

MUS; MYCOBACTERIUM TUBERCULOSIS;

EID: 49249132882     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2008.06365.x     Document Type: Article

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