Susceptibility and mode of binding of the Mycobacterium tuberculosis cysteinyl transferase mycothiol ligase to tRNA synthetase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 8, 2011, Pages 2480-2483

  Gutierrez Lugo, Maria Teresa ^a,b   Bewley, Carole A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b Center for Drug Evaluation and Research   (United States)

Author keywords

Aminoacyl adenosine; Antituberculars; Mycobacteria; Mycothiol; STD NMR

Indexed keywords

AMINO ACID; AMINO ACID TRANSFER RNA LIGASE; AMINO ACID TRANSFER RNA LIGASE INHIBITOR; LIGASE INHIBITOR; MYCOTHIOL LIGASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GROWTH; BIOSYNTHESIS; ENZYME BINDING; ISOTHERMAL TITRATION CALORIMETRY; MYCOBACTERIUM TUBERCULOSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ADENOSINE; AMINO ACID SEQUENCE; AMINO ACYL-TRNA SYNTHETASES; BACTERIAL PROTEINS; BIOLOGICAL PRODUCTS; LIGASES; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PROTEIN BINDING; SEQUENCE ALIGNMENT;

CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 79953284147     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.02.042     Document Type: Article

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