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Volumn 14, Issue 1, 2013, Pages 9-22

Studying genomic processes at the single-molecule level: Introducing the tools and applications

Author keywords

[No Author keywords available]

Indexed keywords

DNA; INITIATION FACTOR; MESSENGER RNA; RNA; RNA POLYMERASE; TRANSFER RNA;

EID: 84871513032     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg3316     Document Type: Review
Times cited : (79)

References (135)
  • 1
    • 80053628299 scopus 로고    scopus 로고
    • Sequencing technologies and genome sequencing
    • Pareek, C. S., Smoczynski, R. & Tretyn, A. Sequencing technologies and genome sequencing. J. Appl. Genet. 52, 413-435 (2011
    • (2011) J. Appl. Genet , vol.52 , pp. 413-435
    • Pareek, C.S.1    Smoczynski, R.2    Tretyn, A.3
  • 2
    • 77952545470 scopus 로고    scopus 로고
    • Single-Molecule imaging brings Rad51 nucleoprotein filaments into focus
    • Forget, A. L. & Kowalczykowski, S. C. Single-Molecule imaging brings Rad51 nucleoprotein filaments into focus. Trends Cell Biol. 20, 269-276 (2010
    • (2010) Trends Cell Biol , vol.20 , pp. 269-276
    • Forget, A.L.1    Kowalczykowski, S.C.2
  • 3
    • 58149352850 scopus 로고    scopus 로고
    • Single molecule studies of homologous recombination
    • Finkelstein, I. J. & Greene, E. C. Single molecule studies of homologous recombination. Mol. Biosyst. 4, 1094-1104 (2008
    • (2008) Mol. Biosyst , vol.4 , pp. 1094-1104
    • Finkelstein, I.J.1    Greene, E.C.2
  • 5
    • 0015132725 scopus 로고
    • Structure of replicating simian virus 40 deoxyribonucleic acid molecules
    • Sebring, E. D., Kelly, T. J. Jr, Thoren, M. M. & Salzman, N. P. Structure of replicating simian virus 40 deoxyribonucleic acid molecules. J. Virol. 8, 478-490 (1971
    • (1971) J. Virol , vol.8 , pp. 478-490
    • Sebring, E.D.1    Kelly Jr., T.J.2    Thoren, M.M.3    Salzman, N.P.4
  • 6
    • 0025707019 scopus 로고
    • Template supercoiling by a chimera of yeast GAL4 protein and phage T7 RNA polymerase
    • Ostrander, E. A., Benedetti, P. & Wang, J. C. Template supercoiling by a chimera of yeast GAL4 protein and phage T7 RNA polymerase. Science 249, 1261-1265 (1990
    • (1990) Science , vol.249 , pp. 1261-1265
    • Ostrander, E.A.1    Benedetti, P.2    Wang, J.C.3
  • 7
    • 0021288941 scopus 로고
    • Patch clamp techniques for studying ionic channels in excitable membranes
    • Neher, E. & Sakmann, B. Patch clamp techniques for studying ionic channels in excitable membranes. Annu. Rev. Physiol. 46, 455-472 (1984
    • (1984) Annu. Rev. Physiol , vol.46 , pp. 455-472
    • Neher, E.1    Sakmann, B.2
  • 8
    • 0040391480 scopus 로고
    • Single pentacene molecules detected by fluorescence excitation in a p terphenyl crystal
    • Orrit, M. & Bernard, J. Single pentacene molecules detected by fluorescence excitation in a p terphenyl crystal. Phys. Rev. Lett. 65, 2716-2719 (1990
    • (1990) Phys. Rev. Lett , vol.65 , pp. 2716-2719
    • Orrit, M.1    Bernard, J.2
  • 9
    • 0027768732 scopus 로고
    • Single molecules observed by near-field scanning optical microscopy
    • Betzig, E. & Chichester, R. J. Single molecules observed by near-field scanning optical microscopy. Science 262, 1422-1425 (1993
    • (1993) Science , vol.262 , pp. 1422-1425
    • Betzig, E.1    Chichester, R.J.2
  • 10
    • 23444431611 scopus 로고
    • Green fluorescent protein as a marker for gene expression
    • Chalfie, M., Tu, Y., Euskirchen, G., Ward, W. W. & Prasher, D. C. Green fluorescent protein as a marker for gene expression. Science 263, 802-805 (1994
    • (1994) Science , vol.263 , pp. 802-805
    • Chalfie, M.1    Tu, Y.2    Euskirchen, G.3    Ward, W.W.4    Prasher, D.C.5
  • 11
    • 0032582494 scopus 로고    scopus 로고
    • Force and velocity measured for single molecules of RNA polymerase
    • Wang, M. D. et al. Force and velocity measured for single molecules of RNA polymerase. Science 282, 902-907 (1998
    • (1998) Science , vol.282 , pp. 902-907
    • Wang, M.D.1
  • 12
    • 80052008241 scopus 로고    scopus 로고
    • Linking RNA polymerase backtracking to genome instability in E coli
    • Dutta, D., Shatalin, K., Epshtein, V., Gottesman, M. E. & Nudler, E. Linking RNA polymerase backtracking to genome instability in E. coli. Cell 146, 533-543 (2011
    • (2011) Cell , vol.146 , pp. 533-543
    • Dutta, D.1    Shatalin, K.2    Epshtein, V.3    Gottesman, M.E.4    Nudler, E.5
  • 13
    • 15844383117 scopus 로고    scopus 로고
    • Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB
    • Koster, D. A., Croquette, V., Dekker, C., Shuman, S. & Dekker, N. H. Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB. Nature 434, 671-674 (2005
    • (2005) Nature , vol.434 , pp. 671-674
    • Koster, D.A.1    Croquette, V.2    Dekker, C.3    Shuman, S.4    Dekker, N.H.5
  • 14
    • 68949208665 scopus 로고    scopus 로고
    • Protein friction limits diffusive and directed movements of kinesin motors on microtubules
    • Bormuth, V., Varga, V., Howard, J. & Schaffer, E. Protein friction limits diffusive and directed movements of kinesin motors on microtubules. Science 325, 870-873 (2009
    • (2009) Science , vol.325 , pp. 870-873
    • Bormuth, V.1    Varga, V.2    Howard, J.3    Schaffer, E.4
  • 15
    • 0025867008 scopus 로고
    • Transcription by single molecules of RNA polymerase observed by light microscopy
    • Schafer, D. A., Gelles, J., Sheetz, M. P. & Landick, R. Transcription by single molecules of RNA polymerase observed by light microscopy. Nature 352, 444-448 (1991
    • (1991) Nature , vol.352 , pp. 444-448
    • Schafer, D.A.1    Gelles, J.2    Sheetz, M.P.3    Landick, R.4
  • 16
    • 84857311371 scopus 로고    scopus 로고
    • Mechanism of transcription initiation at an activator-Dependent promoter defined by single-Molecule observation
    • Friedman, L. J. & Gelles, J. Mechanism of transcription initiation at an activator-Dependent promoter defined by single-Molecule observation. Cell 148, 679-689 (2012
    • (2012) Cell , vol.148 , pp. 679-689
    • Friedman, L.J.1    Gelles, J.2
  • 17
    • 33751212468 scopus 로고    scopus 로고
    • Initial transcription by RNA polymerase proceeds through a DNA-Scrunching mechanism
    • Kapanidis, A. N. et al. Initial transcription by RNA polymerase proceeds through a DNA-Scrunching mechanism. Science 314, 1144-1147 (2006
    • (2006) Science , vol.314 , pp. 1144-1147
    • Kapanidis, A.N.1
  • 18
    • 33751218319 scopus 로고    scopus 로고
    • Abortive initiation and productive initiation by RNA polymerase involve DNA scrunching
    • Revyakin, A., Liu, C., Ebright, R. H. & Strick, T. R. Abortive initiation and productive initiation by RNA polymerase involve DNA scrunching. Science 314, 1139-1143 (2006
    • (2006) Science , vol.314 , pp. 1139-1143
    • Revyakin, A.1    Liu, C.2    Ebright, R.H.3    Strick, T.R.4
  • 19
    • 84860334486 scopus 로고    scopus 로고
    • Dynamic architecture of a minimal RNA polymerase II open promoter complex
    • Treutlein, B. et al. Dynamic architecture of a minimal RNA polymerase II open promoter complex. Mol. Cell 46, 136-146 (2012
    • (2012) Mol. Cell , vol.46 , pp. 136-146
    • Treutlein, B.1
  • 21
    • 0345047725 scopus 로고    scopus 로고
    • Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking
    • Neuman, K. C., Abbondanzieri, E. A., Landick, R., Gelles, J. & Block, S. M. Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking. Cell 115, 437-447 (2003
    • (2003) Cell , vol.115 , pp. 437-447
    • Neuman, K.C.1    Abbondanzieri, E.A.2    Landick, R.3    Gelles, J.4    Block, S.M.5
  • 22
    • 33744981369 scopus 로고    scopus 로고
    • Sequence-Resolved detection of pausing by single RNA polymerase molecules
    • Herbert, K. M. et al. Sequence-Resolved detection of pausing by single RNA polymerase molecules. Cell 125, 1083-1094 (2006
    • (2006) Cell , vol.125 , pp. 1083-1094
    • Herbert, K.M.1
  • 23
    • 0346258014 scopus 로고    scopus 로고
    • Backtracking by single RNA polymerase molecules observed at near-Base-pair resolution
    • Shaevitz, J. W., Abbondanzieri, E. A., Landick, R. & Block, S. M. Backtracking by single RNA polymerase molecules observed at near-Base-pair resolution. Nature 426, 684-687 (2003
    • (2003) Nature , vol.426 , pp. 684-687
    • Shaevitz, J.W.1    Abbondanzieri, E.A.2    Landick, R.3    Block, S.M.4
  • 24
    • 34147206187 scopus 로고    scopus 로고
    • Backtracking determines the force sensitivity of RNAP II in a factor-Dependent manner
    • Galburt, E. A. et al. Backtracking determines the force sensitivity of RNAP II in a factor-Dependent manner. Nature 446, 820-823 (2007
    • (2007) Nature , vol.446 , pp. 820-823
    • Galburt, E.A.1
  • 25
    • 66149143165 scopus 로고    scopus 로고
    • The origin of short transcriptional pauses
    • Depken, M., Galburt, E. A. & Grill, S. W. The origin of short transcriptional pauses. Biophys. J. 96, 2189-2193 (2009
    • (2009) Biophys. J. , vol.96 , pp. 2189-2193
    • Depken, M.1    Galburt, E.A.2    Grill, S.W.3
  • 26
    • 50149118845 scopus 로고    scopus 로고
    • Thermal probing of E coli RNA polymerase off-pathway mechanisms
    • Mejia, Y. X., Mao, H., Forde, N. R. & Bustamante, C. Thermal probing of E. coli RNA polymerase off-pathway mechanisms. J. Mol. Biol. 382, 628-637 (2008
    • (2008) J. Mol. Biol , vol.382 , pp. 628-637
    • Mejia, Y.X.1    Mao, H.2    Forde, N.R.3    Bustamante, C.4
  • 27
    • 81355150826 scopus 로고    scopus 로고
    • Applied force provides insight into transcriptional pausing and its modulation by transcription factor NusA
    • Zhou, J., Ha, K. S., La Porta, A., Landick, R. & Block, S. M. Applied force provides insight into transcriptional pausing and its modulation by transcription factor NusA. Mol. Cell 44, 635-646 (2011
    • (2011) Mol. Cell , vol.44 , pp. 635-646
    • Zhou, J.1    Ha, K.S.2    La Porta, A.3    Landick, R.4    Block, S.M.5
  • 28
    • 77953082083 scopus 로고    scopus 로고
    • E coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase
    • Herbert, K. M. et al. E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase. J. Mol. Biol. 399, 17-30 (2010
    • (2010) J. Mol. Biol , vol.399 , pp. 17-30
    • Herbert, K.M.1
  • 29
    • 33745965527 scopus 로고    scopus 로고
    • Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing
    • Dalal, R. V. et al. Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing. Mol. Cell 23, 231-239 (2006
    • (2006) Mol. Cell , vol.23 , pp. 231-239
    • Dalal, R.V.1
  • 30
    • 79953855317 scopus 로고    scopus 로고
    • A unified model of transcription elongation: What have we learned from single-Molecule experiments?
    • Maoileidigh, D. O., Tadigotla, V. R., Nudler, E. & Ruckenstein, A. E. A unified model of transcription elongation: What have we learned from single-Molecule experiments? Biophys. J. 100, 1157-1166 (2011
    • (2011) Biophys J. , vol.100 , pp. 1157-1166
    • Maoileidigh, D.O.1    Tadigotla, V.R.2    Nudler, E.3    Ruckenstein, A.E.4
  • 31
    • 38349008878 scopus 로고    scopus 로고
    • Fluctuations pauses, and backtracking in DNA transcription
    • Voliotis, M., Cohen, N., Molina-Paris, C. & Liverpool, T. B. Fluctuations, pauses, and backtracking in DNA transcription. Biophys. J. 94, 334-348 (2008
    • (2008) Biophys. J. , vol.94 , pp. 334-348
    • Voliotis, M.1    Cohen, N.2    Molina-Paris, C.3    Liverpool, T.B.4
  • 32
    • 68149120313 scopus 로고    scopus 로고
    • Nucleosomal fluctuations govern the transcription dynamics of RNA polymerase II
    • Hodges, C., Bintu, L., Lubkowska, L., Kashlev, M. & Bustamante, C. Nucleosomal fluctuations govern the transcription dynamics of RNA polymerase II. Science 325, 626-628 (2009
    • (2009) Science , vol.325 , pp. 626-628
    • Hodges, C.1    Bintu, L.2    Lubkowska, L.3    Kashlev, M.4    Bustamante, C.5
  • 33
    • 34548507690 scopus 로고    scopus 로고
    • In vivo dynamics of RNA polymerase II transcription
    • Darzacq, X. et al. In vivo dynamics of RNA polymerase II transcription. Nature Struct. Mol. Biol. 14, 796-806 (2007
    • (2007) Nature Struct. Mol. Biol , vol.14 , pp. 796-806
    • Darzacq, X.1
  • 34
    • 40749096382 scopus 로고    scopus 로고
    • Applied force reveals mechanistic and energetic details of transcription termination
    • Larson, M. H., Greenleaf, W. J., Landick, R. & Block, S. M. Applied force reveals mechanistic and energetic details of transcription termination. Cell 132, 971-982 (2008
    • (2008) Cell , vol.132 , pp. 971-982
    • Larson, M.H.1    Greenleaf, W.J.2    Landick, R.3    Block, S.M.4
  • 35
    • 0033120034 scopus 로고    scopus 로고
    • The mechanism of intrinsic transcription termination
    • Gusarov, I. & Nudler, E. The mechanism of intrinsic transcription termination. Mol. Cell 3, 495-504 (1999
    • (1999) Mol. Cell , vol.3 , pp. 495-504
    • Gusarov, I.1    Nudler, E.2
  • 36
    • 79551680953 scopus 로고    scopus 로고
    • Dynamics of the translational machinery
    • Petrov, A. et al. Dynamics of the translational machinery. Curr. Opin. Struct. Biol. 21, 137-145 (2011
    • (2011) Curr. Opin. Struct. Biol , vol.21 , pp. 137-145
    • Petrov, A.1
  • 37
    • 67649646602 scopus 로고    scopus 로고
    • GTP hydrolysis by IF2 guides progression of the ribosome into elongation
    • Marshall, R. A., Aitken, C. E. & Puglisi, J. D. GTP hydrolysis by IF2 guides progression of the ribosome into elongation. Mol. Cell 35, 37-47 (2009
    • (2009) Mol. Cell , vol.35 , pp. 37-47
    • Marshall, R.A.1    Aitken, C.E.2    Puglisi, J.D.3
  • 38
    • 44449125068 scopus 로고    scopus 로고
    • Spontaneous intersubunit rotation in single ribosomes
    • Cornish, P. V., Ermolenko, D. N., Noller, H. F. & Ha, T. Spontaneous intersubunit rotation in single ribosomes. Mol. Cell 30, 578-588 (2008
    • (2008) Mol. Cell , vol.30 , pp. 578-588
    • Cornish, P.V.1    Ermolenko, D.N.2    Noller, H.F.3    Ha, T.4
  • 39
    • 77954383845 scopus 로고    scopus 로고
    • Following the intersubunit conformation of the ribosome during translation in real time
    • Aitken, C. E. & Puglisi, J. D. Following the intersubunit conformation of the ribosome during translation in real time. Nature Struct. Mol. Biol. 17, 793-800 (2010
    • (2010) Nature Struct. Mol. Biol , vol.17 , pp. 793-800
    • Aitken, C.E.1    Puglisi, J.D.2
  • 40
    • 33847051154 scopus 로고    scopus 로고
    • Identification of two distinct hybrid state intermediates on the ribosome
    • Munro, J. B., Altman, R. B., O'Connor, N. & Blanchard, S. C. Identification of two distinct hybrid state intermediates on the ribosome. Mol. Cell 25, 505-517 (2007
    • (2007) Mol. Cell , vol.25 , pp. 505-517
    • Munro, J.B.1    Altman, R.B.2    O'Connor, N.3    Blanchard, S.C.4
  • 41
    • 41149155366 scopus 로고    scopus 로고
    • Following translation by single ribosomes one codon at a time
    • Wen, J. D. et al. Following translation by single ribosomes one codon at a time. Nature 452, 598-603 (2008
    • (2008) Nature , vol.452 , pp. 598-603
    • Wen, J.D.1
  • 42
    • 33646557329 scopus 로고    scopus 로고
    • A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting
    • Namy, O., Moran, S. J., Stuart, D. I., Gilbert, R. J. & Brierley, I. A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting. Nature 441, 244-247 (2006
    • (2006) Nature , vol.441 , pp. 244-247
    • Namy, O.1    Moran, S.J.2    Stuart, D.I.3    Gilbert, R.J.4    Brierley, I.5
  • 43
    • 58149234737 scopus 로고    scopus 로고
    • Real-Time DNA sequencing from single polymerase molecules
    • Eid, J. et al. Real-Time DNA sequencing from single polymerase molecules. Science 323, 133-138 (2009
    • (2009) Science , vol.323 , pp. 133-138
    • Eid, J.1
  • 44
    • 77951107295 scopus 로고    scopus 로고
    • Real-Time tRNA transit on single translating ribosomes at codon resolution
    • Uemura, S. et al. Real-Time tRNA transit on single translating ribosomes at codon resolution. Nature 464, 1012-1017 (2010
    • (2010) Nature , vol.464 , pp. 1012-1017
    • Uemura, S.1
  • 45
    • 70350602056 scopus 로고    scopus 로고
    • The structure of the ribosome with elongation factor G trapped in the posttranslocational state
    • Gao, Y. G. et al. The structure of the ribosome with elongation factor G trapped in the posttranslocational state. Science 326, 694-699 (2009
    • (2009) Science , vol.326 , pp. 694-699
    • Gao, Y.G.1
  • 46
    • 68249151083 scopus 로고    scopus 로고
    • Translation factors direct intrinsic ribosome dynamics during translation termination and ribosome recycling
    • Sternberg, S. H., Fei, J., Prywes, N., McGrath, K. A. & Gonzalez, R. L. Jr. Translation factors direct intrinsic ribosome dynamics during translation termination and ribosome recycling. Nature Struct. Mol. Biol. 16, 861-868 (2009
    • (2009) Nature Struct. Mol. Biol , vol.16 , pp. 861-868
    • Sternberg, S.H.1    Fei, J.2    Prywes, N.3    McGrath, K.A.4    Gonzalez Jr., R.L.5
  • 48
    • 4444284306 scopus 로고    scopus 로고
    • Imaging of single-Molecule translocation through nuclear pore complexes
    • Yang, W., Gelles, J. & Musser, S. M. Imaging of single-Molecule translocation through nuclear pore complexes. Proc. Natl Acad. Sci. USA 101, 12887-12892 (2004
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 12887-12892
    • Yang, W.1    Gelles, J.2    Musser, S.M.3
  • 49
    • 13844264432 scopus 로고    scopus 로고
    • Nuclear transport of single molecules: Dwell times at the nuclear pore complex
    • Kubitscheck, U. et al. Nuclear transport of single molecules: Dwell times at the nuclear pore complex. J. Cell Biol. 168, 233-243 (2005
    • (2005) J. Cell Biol , vol.168 , pp. 233-243
    • Kubitscheck, U.1
  • 50
    • 77957343471 scopus 로고    scopus 로고
    • Selectivity mechanism of the nuclear pore complex characterized by single cargo tracking
    • Lowe, A. R. et al. Selectivity mechanism of the nuclear pore complex characterized by single cargo tracking. Nature 467, 600-603 (2010
    • (2010) Nature , vol.467 , pp. 600-603
    • Lowe, A.R.1
  • 51
    • 80053353760 scopus 로고    scopus 로고
    • Single molecule study of the intrinsically disordered FG repeat nucleoporin 153
    • Milles, S. & Lemke, E. A. Single molecule study of the intrinsically disordered FG repeat nucleoporin 153. Biophys. J. 101, 1710-1719 (2011
    • (2011) Biophys. J. , vol.101 , pp. 1710-1719
    • Milles, S.1    Lemke, E.A.2
  • 52
    • 79960098185 scopus 로고    scopus 로고
    • Single-Molecule transport across an individual biomimetic nuclear pore complex
    • Kowalczyk, S. W. et al. Single-Molecule transport across an individual biomimetic nuclear pore complex. Nature Nanotechnol. 6, 433-438 (2011
    • (2011) Nature Nanotechnol , vol.6 , pp. 433-438
    • Kowalczyk, S.W.1
  • 53
    • 77957370148 scopus 로고    scopus 로고
    • In vivo imaging of labelled endogenous β-Actin mRNA during nucleocytoplasmic transport
    • Grunwald, D. & Singer, R. H. In vivo imaging of labelled endogenous β-Actin mRNA during nucleocytoplasmic transport. Nature 467, 604-607 (2010
    • (2010) Nature , vol.467 , pp. 604-607
    • Grunwald, D.1    Singer, R.H.2
  • 54
    • 77950516144 scopus 로고    scopus 로고
    • Conformational dynamics of single pre-MRNA molecules during in vitro splicing
    • Abelson, J. et al. Conformational dynamics of single pre-MRNA molecules during in vitro splicing. Nature Struct. Mol. Biol. 17, 504-512 (2010
    • (2010) Nature Struct. Mol. Biol , vol.17 , pp. 504-512
    • Abelson, J.1
  • 55
    • 78049234242 scopus 로고    scopus 로고
    • Single-Molecule analysis of Mss116 mediated group II intron folding
    • Karunatilaka, K. S., Solem, A., Pyle, A. M. & Rueda, D. Single-Molecule analysis of Mss116 mediated group II intron folding. Nature 467, 935-939 (2010
    • (2010) Nature , vol.467 , pp. 935-939
    • Karunatilaka, K.S.1    Solem, A.2    Pyle, A.M.3    Rueda, D.4
  • 56
    • 79952504644 scopus 로고    scopus 로고
    • Ordered and dynamic assembly of single spliceosomes
    • Hoskins, A. A. et al. Ordered and dynamic assembly of single spliceosomes. Science 331, 1289-1295 (2011
    • (2011) Science , vol.331 , pp. 1289-1295
    • Hoskins, A.A.1
  • 57
    • 79960088946 scopus 로고    scopus 로고
    • Cell to cell variability of alternative RNA splicing
    • Waks, Z., Klein, A. M. & Silver, P. A. Cell to cell variability of alternative RNA splicing. Mol. Syst. Biol. 7, 506 (2011
    • (2011) Mol. Syst. Biol , vol.7 , pp. 506
    • Waks, Z.1    Klein, A.M.2    Silver, P.A.3
  • 58
    • 81855183655 scopus 로고    scopus 로고
    • Single-Molecule imaging of transcriptionally coupled and uncoupled splicing
    • Vargas, D. Y. et al. Single-Molecule imaging of transcriptionally coupled and uncoupled splicing. Cell 147, 1054-1065 (2011
    • (2011) Cell , vol.147 , pp. 1054-1065
    • Vargas, D.Y.1
  • 59
    • 33744950932 scopus 로고    scopus 로고
    • Replisome architecture and dynamics in Escherichia coli
    • O'Donnell, M. Replisome architecture and dynamics in Escherichia coli. J. Biol. Chem. 281, 10653-10656 (2006
    • (2006) J. Biol. Chem , vol.281 , pp. 10653-10656
    • O'Donnell, M.1
  • 60
    • 50049117482 scopus 로고    scopus 로고
    • The bacterial replisome: Back on track?
    • Bates, D. The bacterial replisome: Back on track? Mol. Microbiol. 69, 1341-1348 (2008
    • (2008) Mol. Microbiol , vol.69 , pp. 1341-1348
    • Bates, D.1
  • 61
    • 77953710831 scopus 로고    scopus 로고
    • Snap shot: The replisome
    • Yao, N. Y. & O'Donnell, M. SnapShot: The replisome. Cell 141, 1088-1088.e1 (2010
    • (2010) Cell , vol.141
    • Yao, N.Y.1    O'Donnell, M.2
  • 63
    • 22244478079 scopus 로고    scopus 로고
    • Cellular DNA replicases: Components and dynamics at the replication fork
    • Johnson, A. & O'Donnell, M. Cellular DNA replicases: Components and dynamics at the replication fork. Annu. Rev. Biochem. 74, 283-315 (2005
    • (2005) Annu. Rev. Biochem , vol.74 , pp. 283-315
    • Johnson, A.1    O'Donnell, M.2
  • 64
    • 0034710990 scopus 로고    scopus 로고
    • Replication by a single DNA polymerase of a stretched single-Stranded DNA
    • Maier, B., Bensimon, D. & Croquette, V. Replication by a single DNA polymerase of a stretched single-Stranded DNA. Proc. Natl Acad. Sci. USA 97, 12002-12007 (2000
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 12002-12007
    • Maier, B.1    Bensimon, D.2    Croquette, V.3
  • 65
    • 72449179248 scopus 로고    scopus 로고
    • Coupling DNA unwinding activity with primer synthesis in the bacteriophage T4 primosome
    • Manosas, M., Spiering, M. M., Zhuang, Z., Benkovic, S. J. & Croquette, V. Coupling DNA unwinding activity with primer synthesis in the bacteriophage T4 primosome. Nature Chem. Biol. 5, 904-912 (2009
    • (2009) Nature Chem. Biol , vol.5 , pp. 904-912
    • Manosas, M.1    Spiering, M.M.2    Zhuang, Z.3    Benkovic, S.J.4    Croquette, V.5
  • 66
    • 77958475756 scopus 로고    scopus 로고
    • DNAB helicase activity is modulated by DNA geometry and force
    • Ribeck, N., Kaplan, D. L., Bruck, I. & Saleh, O. A. DNAB helicase activity is modulated by DNA geometry and force. Biophys. J. 99, 2170-2179 (2010
    • (2010) Biophys. J. , vol.99 , pp. 2170-2179
    • Ribeck, N.1    Kaplan, D.L.2    Bruck, I.3    Saleh, O.A.4
  • 67
    • 34250766751 scopus 로고    scopus 로고
    • Single-Molecule studies reveal dynamics of DNA unwinding by the ring-Shaped T7 helicase
    • Johnson, D. S., Bai, L., Smith, B. Y., Patel, S. S. & Wang, M. D. Single-Molecule studies reveal dynamics of DNA unwinding by the ring-Shaped T7 helicase. Cell 129, 1299-1309 (2007
    • (2007) Cell , vol.129 , pp. 1299-1309
    • Johnson, D.S.1    Bai, L.2    Smith, B.Y.3    Patel, S.S.4    Wang, M.D.5
  • 68
    • 79960804204 scopus 로고    scopus 로고
    • SSB functions as a sliding platform that migrates on DNA via reptation
    • Zhou, R. et al. SSB functions as a sliding platform that migrates on DNA via reptation. Cell 146, 222-232 (2011
    • (2011) Cell , vol.146 , pp. 222-232
    • Zhou, R.1
  • 69
    • 84864447544 scopus 로고    scopus 로고
    • Collaborative coupling between polymerase and helicase for leading-Strand synthesis
    • Manosas, M., Spiering, M. M., Ding, F., Croquette, V. & Benkovic, S. J. Collaborative coupling between polymerase and helicase for leading-Strand synthesis. Nucleic Acids Res. 40, 6187-6198 (2012
    • (2012) Nucleic Acids Res , vol.40 , pp. 6187-6198
    • Manosas, M.1    Spiering, M.M.2    Ding, F.3    Croquette, V.4    Benkovic, S.J.5
  • 70
    • 31844453991 scopus 로고    scopus 로고
    • DNA primase acts as a molecular brake in DNA replication
    • Lee, J. B. et al. DNA primase acts as a molecular brake in DNA replication. Nature 439, 621-624 (2006
    • (2006) Nature , vol.439 , pp. 621-624
    • Lee, J.B.1
  • 71
    • 38849174361 scopus 로고    scopus 로고
    • Single-Molecule studies of fork dynamics in Escherichia coli DNA replication
    • Tanner, N. A. et al. Single-Molecule studies of fork dynamics in Escherichia coli DNA replication. Nature Struct. Mol. Biol. 15, 170-176 (2008
    • (2008) Nature Struct. Mol. Biol , vol.15 , pp. 170-176
    • Tanner, N.A.1
  • 73
    • 72449204579 scopus 로고    scopus 로고
    • Coordinating DNA replication by means of priming loop and differential synthesis rate
    • Pandey, M. et al. Coordinating DNA replication by means of priming loop and differential synthesis rate. Nature 462, 940-943 (2009
    • (2009) Nature , vol.462 , pp. 940-943
    • Pandey, M.1
  • 74
    • 34547730912 scopus 로고    scopus 로고
    • Characterization of a triple DNA polymerase replisome
    • McInerney, P., Johnson, A., Katz, F. & O'Donnell, M. Characterization of a triple DNA polymerase replisome. Mol. Cell 27, 527-538 (2007
    • (2007) Mol. Cell , vol.27 , pp. 527-538
    • McInerney, P.1    Johnson, A.2    Katz, F.3    O'Donnell, M.4
  • 75
    • 34547850193 scopus 로고    scopus 로고
    • Polymerase switching in DNA replication
    • Lovett, S. T. Polymerase switching in DNA replication. Mol. Cell 27, 523-526 (2007
    • (2007) Mol. Cell , vol.27 , pp. 523-526
    • Lovett, S.T.1
  • 76
    • 48249095613 scopus 로고    scopus 로고
    • Single-Molecule approach to molecular biology in living bacterial cells
    • Xie, X. S., Choi, P. J., Li, G. W., Lee, N. K. & Lia, G. Single-Molecule approach to molecular biology in living bacterial cells. Annu. Rev. Biophys. 37, 417-444 (2008
    • (2008) Annu. Rev. Biophys , vol.37 , pp. 417-444
    • Xie, X.S.1    Choi, P.J.2    Li, G.W.3    Lee, N.K.4    Lia, G.5
  • 77
    • 77951537332 scopus 로고    scopus 로고
    • Stoichiometry and architecture of active DNA replication machinery in Escherichia coli
    • Reyes-Lamothe, R., Sherratt, D. J. & Leake, M. C. Stoichiometry and architecture of active DNA replication machinery in Escherichia coli. Science 328, 498-501 (2010
    • (2010) Science , vol.328 , pp. 498-501
    • Reyes-Lamothe, R.1    Sherratt, D.J.2    Leake, M.C.3
  • 78
    • 84856072129 scopus 로고    scopus 로고
    • Polymerase exchange during Okazaki fragment synthesis observed in living cells
    • Lia, G., Michel, B. & Allemand, J. F. Polymerase exchange during Okazaki fragment synthesis observed in living cells. Science 335, 328-331 (2012
    • (2012) Science , vol.335 , pp. 328-331
    • Lia, G.1    Michel, B.2    Allemand, J.F.3
  • 79
    • 84855453503 scopus 로고    scopus 로고
    • Single-Molecule studies reveal the function of a third polymerase in the replisome
    • Georgescu, R. E., Kurth, I. & O'Donnell, M. E. Single-Molecule studies reveal the function of a third polymerase in the replisome. Nature Struct. Mol. Biol. 19, 113-116 (2012
    • (2012) Nature Struct. Mol. Biol , vol.19 , pp. 113-116
    • Georgescu, R.E.1    Kurth, I.2    O'Donnell, M.E.3
  • 80
    • 79959431646 scopus 로고    scopus 로고
    • Replicases from a bacterial perspective
    • McHenry, C. S. D. N. A. Replicases from a bacterial perspective. Annu. Rev. Biochem. 80, 403-436 (2011
    • (2011) Annu. Rev. Biochem , vol.80 , pp. 403-436
    • McHenry, C.S.D.N.A.1
  • 81
    • 77955629227 scopus 로고    scopus 로고
    • Cellular strategies for regulating DNA supercoiling: A single-Molecule perspective
    • Koster, D. A., Crut, A., Shuman, S., Bjornsti, M. A. & Dekker, N. H. Cellular strategies for regulating DNA supercoiling: A single-Molecule perspective. Cell 142, 519-530 (2010
    • (2010) Cell , vol.142 , pp. 519-530
    • Koster, D.A.1    Crut, A.2    Shuman, S.3    Bjornsti, M.A.4    Dekker, N.H.5
  • 82
    • 78649709362 scopus 로고    scopus 로고
    • Magnetic torque tweezers: Measuring torsional stiffness in DNA and RecA-DNA filaments
    • Lipfert, J., Kerssemakers, J. W., Jager, T. & Dekker, N. H. Magnetic torque tweezers: Measuring torsional stiffness in DNA and RecA-DNA filaments. Nature Methods 7, 977-980 (2010
    • (2010) Nature Methods , vol.7 , pp. 977-980
    • Lipfert, J.1    Kerssemakers, J.W.2    Jager, T.3    Dekker, N.H.4
  • 83
    • 80052404576 scopus 로고    scopus 로고
    • Freely orbiting magnetic tweezers to directly monitor changes in the twist of nucleic acids
    • Lipfert, J., Wiggin, M., Kerssemakers, J. W., Pedaci, F. & Dekker, N. H. Freely orbiting magnetic tweezers to directly monitor changes in the twist of nucleic acids. Nature Commun. 2, 439 (2011
    • (2011) Nature Commun , vol.2 , pp. 439
    • Lipfert, J.1    Wiggin, M.2    Kerssemakers, J.W.3    Pedaci, F.4    Dekker, N.H.5
  • 84
    • 30144434477 scopus 로고    scopus 로고
    • Mechanochemical analysis of DNA gyrase using rotor bead tracking
    • Gore, J. et al. Mechanochemical analysis of DNA gyrase using rotor bead tracking. Nature 439, 100-104 (2006
    • (2006) Nature , vol.439 , pp. 100-104
    • Gore, J.1
  • 85
    • 0041305824 scopus 로고    scopus 로고
    • Structural transitions and elasticity from torque measurements on DNA
    • Bryant, Z. et al. Structural transitions and elasticity from torque measurements on DNA. Nature 424, 338-341 (2003
    • (2003) Nature , vol.424 , pp. 338-341
    • Bryant, Z.1
  • 86
    • 18144444347 scopus 로고    scopus 로고
    • Optical torque wrench: Angular trapping, rotation, and torque detection of quartz microparticles
    • La Porta, A. & Wang, M. D. Optical torque wrench: Angular trapping, rotation, and torque detection of quartz microparticles. Phys. Rev. Lett. 92, 190801 (2004
    • (2004) Phys. Rev. Lett , vol.92 , pp. 190801
    • La Porta, A.1    Wang, M.D.2
  • 87
    • 79953292607 scopus 로고    scopus 로고
    • Ultrahigh-Resolution optical trap with single-fluorophore sensitivity
    • Comstock, M. J., Ha, T. & Chemla, Y. R. Ultrahigh-Resolution optical trap with single-fluorophore sensitivity. Nature Methods 8, 335-340 (2011
    • (2011) Nature Methods , vol.8 , pp. 335-340
    • Comstock, M.J.1    Ha, T.2    Chemla, Y.R.3
  • 88
    • 35348897239 scopus 로고    scopus 로고
    • Fluorescence-force spectroscopy maps two-Dimensional reaction landscape of the Holliday junction
    • Hohng, S. et al. Fluorescence-force spectroscopy maps two-Dimensional reaction landscape of the Holliday junction. Science 318, 279-283 (2007
    • (2007) Science , vol.318 , pp. 279-283
    • Hohng, S.1
  • 89
    • 67650391229 scopus 로고    scopus 로고
    • Mechanical characterization of protein l in the low-force regime by electromagnetic tweezers/evanescent nanometry
    • Liu, R., Garcia-Manyes, S., Sarkar, A., Badilla, C. L. & Fernandez, J. M. Mechanical characterization of protein l in the low-force regime by electromagnetic tweezers/evanescent nanometry. Biophys. J. 96, 3810-3821 (2009
    • (2009) Biophys. J. , vol.96 , pp. 3810-3821
    • Liu, R.1    Garcia-Manyes, S.2    Sarkar, A.3    Badilla, C.L.4    Fernandez, J.M.5
  • 90
    • 33846804071 scopus 로고    scopus 로고
    • Micromanipulation studies of chromatin fibers in Xenopus egg extracts reveal ATP-Dependent chromatin assembly dynamics
    • Yan, J. et al. Micromanipulation studies of chromatin fibers in Xenopus egg extracts reveal ATP-Dependent chromatin assembly dynamics. Mol. Biol. Cell 18, 464-474 (2007
    • (2007) Mol. Biol. Cell , vol.18 , pp. 464-474
    • Yan, J.1
  • 91
    • 79959936612 scopus 로고    scopus 로고
    • Single-Molecule approach to immunoprecipitated protein complexes: Insights into miRNA uridylation
    • Yeom, K. H. et al. Single-Molecule approach to immunoprecipitated protein complexes: Insights into miRNA uridylation. EMBO Rep. 12, 690-696 (2011
    • (2011) EMBO Rep , vol.12 , pp. 690-696
    • Yeom, K.H.1
  • 92
    • 79957590332 scopus 로고    scopus 로고
    • Probing cellular protein complexes using single-Molecule pull-Down
    • Jain, A. et al. Probing cellular protein complexes using single-Molecule pull-Down. Nature 473, 484-488 (2011
    • (2011) Nature , vol.473 , pp. 484-488
    • Jain, A.1
  • 93
    • 54749117023 scopus 로고    scopus 로고
    • Multiplexed single-Molecule measurements with magnetic tweezers
    • Ribeck, N. & Saleh, O. A. Multiplexed single-Molecule measurements with magnetic tweezers. Rev. Sci. Instrum. 79, 094301 (2008
    • (2008) Rev. Sci. Instrum , vol.79 , pp. 094301
    • Ribeck, N.1    Saleh, O.A.2
  • 94
    • 81255146230 scopus 로고    scopus 로고
    • The three-Dimensional architecture of a bacterial genome and its alteration by genetic perturbation
    • Umbarger, M. A. et al. The three-Dimensional architecture of a bacterial genome and its alteration by genetic perturbation. Mol. Cell 44, 252-264 (2011
    • (2011) Mol. Cell , vol.44 , pp. 252-264
    • Umbarger, M.A.1
  • 95
    • 80052803313 scopus 로고    scopus 로고
    • Binding-Activated localization microscopy of DNA structures
    • Schoen, I., Ries, J., Klotzsch, E., Ewers, H. & Vogel, V. Binding-Activated localization microscopy of DNA structures. Nano Lett. 11, 4008-4011 (2011
    • (2011) Nano Lett , vol.11 , pp. 4008-4011
    • Schoen, I.1    Ries, J.2    Klotzsch, E.3    Ewers, H.4    Vogel, V.5
  • 97
    • 84861170964 scopus 로고    scopus 로고
    • Single-MRNA counting using fluorescent in situ hybridization in budding yeast
    • Trcek, T. et al. Single-MRNA counting using fluorescent in situ hybridization in budding yeast. Nature Protoc. 7, 408-419 (2012
    • (2012) Nature Protoc , vol.7 , pp. 408-419
    • Trcek, T.1
  • 98
    • 79960959180 scopus 로고    scopus 로고
    • RNA mimics of green fluorescent protein
    • Paige, J. S., Wu, K. Y. & Jaffrey, S. R. RNA mimics of green fluorescent protein. Science 333, 642-646 (2011
    • (2011) Science , vol.333 , pp. 642-646
    • Paige, J.S.1    Wu, K.Y.2    Jaffrey, S.R.3
  • 99
    • 79959670132 scopus 로고    scopus 로고
    • Super-Resolution imaging of the nucleoid-Associated protein HU in Caulobacter crescentus
    • Lee, S. F., Thompson, M. A., Schwartz, M. A., Shapiro, L. & Moerner, W. E. Super-Resolution imaging of the nucleoid-Associated protein HU in Caulobacter crescentus. Biophys. J. 100, L31-L33 (2011
    • (2011) Biophys. J. , vol.100
    • Lee, S.F.1    Thompson, M.A.2    Schwartz, M.A.3    Shapiro, L.4    Moerner, W.E.5
  • 100
    • 80052643394 scopus 로고    scopus 로고
    • Chromosome organization by a nucleoid-Associated protein in live bacteria
    • Wang, W., Li, G. W., Chen, C., Xie, X. S. & Zhuang, X. Chromosome organization by a nucleoid-Associated protein in live bacteria. Science 333, 1445-1449 (2011
    • (2011) Science , vol.333 , pp. 1445-1449
    • Wang, W.1    Li, G.W.2    Chen, C.3    Xie, X.S.4    Zhuang, X.5
  • 101
    • 56749104130 scopus 로고    scopus 로고
    • Fluorescent probes for super-Resolution imaging in living cells
    • Fernandez-Suarez, M. & Ting, A. Y. Fluorescent probes for super-Resolution imaging in living cells. Nature Rev. Mol. Cell Biol. 9, 929-943 (2008
    • (2008) Nature Rev. Mol. Cell Biol , vol.9 , pp. 929-943
    • Fernandez-Suarez, M.1    Ting, A.Y.2
  • 102
    • 79960277917 scopus 로고    scopus 로고
    • A hitchhiker's guide to mechanobiology
    • Eyckmans, J., Boudou, T., Yu, X. & Chen, C. S. A hitchhiker's guide to mechanobiology. Dev. Cell 21, 35-47 (2011
    • (2011) Dev. Cell , vol.21 , pp. 35-47
    • Eyckmans, J.1    Boudou, T.2    Yu, X.3    Chen, C.S.4
  • 103
    • 79952779058 scopus 로고    scopus 로고
    • Force nanoscopy of living cells
    • Muller, D. J. & Dufrene, Y. F. Force nanoscopy of living cells. Curr. Biol. 21, R212-R216 (2011
    • (2011) Curr. Biol , vol.21
    • Muller, D.J.1    Dufrene, Y.F.2
  • 104
    • 67649840196 scopus 로고    scopus 로고
    • Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues
    • Legant, W. R. et al. Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues. Proc. Natl Acad. Sci. USA 106, 10097-10102 (2009
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 10097-10102
    • Legant, W.R.1
  • 105
    • 79952764128 scopus 로고    scopus 로고
    • Vertical nanopillars for highly localized fluorescence imaging
    • Xie, C., Hanson, L., Cui, Y. & Cui, B. Vertical nanopillars for highly localized fluorescence imaging. Proc. Natl Acad. Sci. USA 108, 3894-3899 (2011
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 3894-3899
    • Xie, C.1    Hanson, L.2    Cui, Y.3    Cui, B.4
  • 106
    • 79955869135 scopus 로고    scopus 로고
    • Microsystems for cellular force measurement: A review
    • Zhang, J. Microsystems for cellular force measurement: A review. J. Micromech. Microeng. 21, 054003 (2011
    • (2011) J. Micromech. Microeng , vol.21 , pp. 054003
    • Zhang, J.1
  • 107
    • 79551525710 scopus 로고    scopus 로고
    • Five challenges to bringing single-Molecule force spectroscopy into living cells
    • Dufrene, Y. F. et al. Five challenges to bringing single-Molecule force spectroscopy into living cells. Nature Methods 8, 123-127 (2011
    • (2011) Nature Methods , vol.8 , pp. 123-127
    • Dufrene, Y.F.1
  • 108
    • 79960098421 scopus 로고    scopus 로고
    • Genetically encoded force sensors for measuring mechanical forces in proteins
    • Wang, Y., Meng, F. & Sachs, F. Genetically encoded force sensors for measuring mechanical forces in proteins. Commun. Integr. Biol. 4, 385-390 (2011
    • (2011) Commun. Integr. Biol , vol.4 , pp. 385-390
    • Wang, Y.1    Meng, F.2    Sachs, F.3
  • 109
    • 67650066687 scopus 로고    scopus 로고
    • Probing dynein and kinesin stepping with mechanical manipulation in a living cell
    • Sims, P. A. & Xie, X. S. Probing dynein and kinesin stepping with mechanical manipulation in a living cell. ChemPhysChem 10, 1511-1516 (2009
    • (2009) ChemPhysChem , vol.10 , pp. 1511-1516
    • Sims, P.A.1    Xie, X.S.2
  • 110
    • 80054702340 scopus 로고    scopus 로고
    • Magnetic manipulation of nanorods in the nucleus of living cells
    • Celedon, A., Hale, C. M. & Wirtz, D. Magnetic manipulation of nanorods in the nucleus of living cells. Biophys. J. 101, 1880-1886 (2011
    • (2011) Biophys. J. , vol.101 , pp. 1880-1886
    • Celedon, A.1    Hale, C.M.2    Wirtz, D.3
  • 111
    • 0142084723 scopus 로고    scopus 로고
    • Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells
    • Hu, S. et al. Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells. Am. J. Physiol. Cell Physiol. 285, C1082-C1090 (2003
    • (2003) Am. J. Physiol. Cell Physiol , vol.285
    • Hu, S.1
  • 112
    • 77954486800 scopus 로고    scopus 로고
    • Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics
    • Grashoff, C. et al. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature 466, 263-266 (2010
    • (2010) Nature , vol.466 , pp. 263-266
    • Grashoff, C.1
  • 113
    • 79251591301 scopus 로고    scopus 로고
    • Visualizing dynamic cytoplasmic forces with a compliance-Matched FRET sensor
    • Meng, F. & Sachs, F. Visualizing dynamic cytoplasmic forces with a compliance-Matched FRET sensor. J. Cell Sci. 124, 261-269 (2011
    • (2011) J. Cell Sci , vol.124 , pp. 261-269
    • Meng, F.1    Sachs, F.2
  • 114
    • 58049211966 scopus 로고    scopus 로고
    • Mechanotransduction at a distance: Mechanically coupling the extracellular matrix with the nucleus
    • Wang, N., Tytell, J. D. & Ingber, D. E. Mechanotransduction at a distance: Mechanically coupling the extracellular matrix with the nucleus. Nature Rev. Mol. Cell Biol. 10, 75-82 (2009
    • (2009) Nature Rev. Mol. Cell Biol , vol.10 , pp. 75-82
    • Wang, N.1    Tytell, J.D.2    Ingber, D.E.3
  • 115
    • 85015087906 scopus 로고    scopus 로고
    • Ten years of tension: Single-Molecule DNA mechanics
    • Bustamante, C., Bryant, Z. & Smith, S. B. Ten years of tension: Single-Molecule DNA mechanics. Nature 421, 423-427 (2003
    • (2003) Nature , vol.421 , pp. 423-427
    • Bustamante, C.1    Bryant, Z.2    Smith, S.B.3
  • 117
    • 44449087047 scopus 로고    scopus 로고
    • Single-Molecule force spectroscopy: Optical tweezers, magnetic tweezers and atomic force microscopy
    • Neuman, K. C. & Nagy, A. Single-Molecule force spectroscopy: Optical tweezers, magnetic tweezers and atomic force microscopy. Nature Methods 5, 491-505 (2008
    • (2008) Nature Methods , vol.5 , pp. 491-505
    • Neuman, K.C.1    Nagy, A.2
  • 118
    • 68949105584 scopus 로고    scopus 로고
    • Quantitative modeling and optimization of magnetic tweezers
    • Lipfert, J., Hao, X. & Dekker, N. H. Quantitative modeling and optimization of magnetic tweezers. Biophys. J. 96, 5040-5049 (2009
    • (2009) Biophys. J. , vol.96 , pp. 5040-5049
    • Lipfert, J.1    Hao, X.2    Dekker, N.H.3
  • 120
    • 77952934028 scopus 로고    scopus 로고
    • Single-Molecule studies of the replisome
    • van Oijen, A. M. & Loparo, J. J. Single-Molecule studies of the replisome. Annu. Rev. Biophys. 39, 429-448 (2010
    • (2010) Annu. Rev. Biophys , vol.39 , pp. 429-448
    • Van Oijen, A.M.1    Loparo, J.J.2
  • 121
    • 27744587245 scopus 로고    scopus 로고
    • Force measurements with the atomic force microscope: Technique, interpretation and applications
    • Butt, H. J., Cappella, B. & Kappl, M. Force measurements with the atomic force microscope: Technique, interpretation and applications. Surf. Sci. Rep. 59, 1-152 (2005
    • (2005) Surf. Sci. Rep , vol.59 , pp. 1-152
    • Butt, H.J.1    Cappella, B.2    Kappl, M.3
  • 125
    • 77952722979 scopus 로고    scopus 로고
    • Type III restriction enzymes cleave DNA by long-Range interaction between sites in both head to head and tail to tail inverted repeat
    • van Aelst, K. et al. Type III restriction enzymes cleave DNA by long-Range interaction between sites in both head to head and tail to tail inverted repeat. Proc. Natl Acad. Sci. USA 107, 9123-9128 (2010
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 9123-9128
    • Van Aelst, K.1
  • 126
    • 70350337095 scopus 로고    scopus 로고
    • Fluorescent proteins: A cell biologist's user guide
    • Snapp, E. L. Fluorescent proteins: A cell biologist's user guide. Trends Cell Biol. 19, 649-655 (2009
    • (2009) Trends Cell Biol , vol.19 , pp. 649-655
    • Snapp, E.L.1
  • 127
    • 60549086229 scopus 로고    scopus 로고
    • Type III restriction enzymes communicate in 1D without looping between their target sites
    • Ramanathan, S. P. et al. Type III restriction enzymes communicate in 1D without looping between their target sites. Proc. Natl Acad. Sci. USA 106, 1748-1753 (2009
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 1748-1753
    • Ramanathan, S.P.1
  • 128
    • 0034760118 scopus 로고    scopus 로고
    • Total internal reflection fluorescence microscopy in cell biology
    • Axelrod, D. Total internal reflection fluorescence microscopy in cell biology. Traffic 2, 764-774 (2001
    • (2001) Traffic , vol.2 , pp. 764-774
    • Axelrod, D.1
  • 129
    • 0036231415 scopus 로고    scopus 로고
    • Precise nanometer localization analysis for individual fluorescent probes
    • Thompson, R. E., Larson, D. R. & Webb, W. W. Precise nanometer localization analysis for individual fluorescent probes. Biophys. J. 82, 2775-2783 (2002
    • (2002) Biophys. J. , vol.82 , pp. 2775-2783
    • Thompson, R.E.1    Larson, D.R.2    Webb, W.W.3
  • 130
    • 33645228946 scopus 로고    scopus 로고
    • Beyond Rayleigh's criterion: A resolution measure with application to single-Molecule microscopy
    • Ram, S., Ward, E. S. & Ober, R. J. Beyond Rayleigh's criterion: A resolution measure with application to single-Molecule microscopy. Proc. Natl Acad. Sci. USA 103, 4457-4462 (2006
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 4457-4462
    • Ram, S.1    Ward, E.S.2    Ober, R.J.3
  • 131
    • 77952216273 scopus 로고    scopus 로고
    • Fast single-Molecule localization that achieves theoretically minimum uncertainty
    • Smith, C. S., Joseph, N., Rieger, B. & Lidke, K. A. Fast, single-Molecule localization that achieves theoretically minimum uncertainty. Nature Methods 7, 373-375 (2010
    • (2010) Nature Methods , vol.7 , pp. 373-375
    • Smith, C.S.1    Joseph, N.2    Rieger, B.3    Lidke, K.A.4
  • 132
    • 77952215650 scopus 로고    scopus 로고
    • Optimized localization analysis for single-Molecule tracking and super-Resolution microscopy
    • Mortensen, K. I., Churchman, L. S., Spudich, J. A. & Flyvbjerg, H. Optimized localization analysis for single-Molecule tracking and super-Resolution microscopy. Nature Methods 7, 377-381 (2010
    • (2010) Nature Methods , vol.7 , pp. 377-381
    • Mortensen, K.I.1    Churchman, L.S.2    Spudich, J.A.3    Flyvbjerg, H.4
  • 133
    • 58149236663 scopus 로고    scopus 로고
    • Microscopy and its focal switch
    • Hell, S. W. Microscopy and its focal switch. Nature Methods 6, 24-32 (2009
    • (2009) Nature Methods , vol.6 , pp. 24-32
    • Hell, S.W.1
  • 135
    • 79960927256 scopus 로고    scopus 로고
    • Single molecule studies of nucleocytoplasmic transport
    • Tu, L. C. & Musser, S. M. Single molecule studies of nucleocytoplasmic transport. Biochim. Biophys. Acta 1813, 1607-1618 (2011
    • (2011) Biochim. Biophys. Acta , vol.1813 , pp. 1607-1618
    • Tu, L.C.1    Musser, S.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.