Stoichiometry and architecture of active DNA replication machinery in escherichia coli

Science

Volumn 328, Issue 5977, 2010, Pages 498-501

  Reyes Lamothe, Rodrigo ^a   Sherratt, David J ^a   Leake, Mark C ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE ALPHA; REPLISOME; TETRAMER;

COLIFORM BACTERIUM; DNA; GENETIC ANALYSIS; PROTEIN; SPATIAL DISTRIBUTION; STOICHIOMETRY;

ARTICLE; CLAMP; CONTROLLED STUDY; DNA REPLICATION; ENZYME STRUCTURE; ESCHERICHIA COLI; FLUORESCENCE MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOICHIOMETRY;

DNA POLYMERASE III; DNA REPLICATION; DNA, BACTERIAL; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MULTIENZYME COMPLEXES; NUCLEIC ACID CONFORMATION;

ESCHERICHIA COLI;

EID: 77951537332     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1185757     Document Type: Article

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29. Supported by the Wellcome Trust and the Royal Society. M.C.L. is a Royal Society University Fellow and research fellow of Hertford College Oxford. R.R.-L. is a research fellow of New College Oxford and was supported by Conacyt and a Clarendon postgraduate award. We thank C. Possoz and C. Lesterlin for stimulating discussions, and we acknowledge National BioResource Project (NIG, Japan): E. coli for the provision of the hole and holD deletion strains.