Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB

Nature

Volumn 434, Issue 7033, 2005, Pages 671-674

  Koster, Daniel A ^a   Croquette, Vincent ^b   Dekker, Cees ^a   Shuman, Stewart ^c   Dekker, Nynke H ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b ECOLE NORMALE SUPÉRIEURE   (France)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES; FRICTION; ISOMERIZATION; MOLECULES; PROTEINS; TORQUE;

ANTI-CANCER DRUGS; CELL PROLIFERATION; TOPOISOMERIZATION; TORSIONAL STRAIN;

DNA;

DNA TOPOISOMERASE; DNA TOPOISOMERASE IB; DOUBLE STRANDED DNA; MUTANT PROTEIN; UNCLASSIFIED DRUG;

DNA;

ARTICLE; DNA SUPERCOILING; ENZYME ACTIVITY; EUKARYOTE; FRICTION; MAGNETIC FIELD; NONHUMAN; PRIORITY JOURNAL; ROTATION; TORQUE; VACCINIA VIRUS; VELOCITY; BIOLOGICAL MODEL; CHEMISTRY; CONFORMATION; ENZYMOLOGY; EUKARYOTIC CELL; HUMAN; METABOLISM; THERMODYNAMICS;

DNA TOPOISOMERASES, TYPE I; DNA, SUPERHELICAL; EUKARYOTIC CELLS; FRICTION; HUMANS; MODELS, BIOLOGICAL; NUCLEIC ACID CONFORMATION; THERMODYNAMICS; TORQUE;

EID: 15844383117     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03395     Document Type: Article

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