-
1
-
-
17544368021
-
Strategies for producing faster acting antidepressants
-
DOI 10.1016/S1359-6446(05)03398-2, PII S1359644605033982
-
Adell, A., Castro, E., Celada, P., Bortolozzi, A., Pazos, A., and Artigas, F. (2005). Strategies for producing faster acting anti depressants. Drug Discov. Today 10, 578-585. (Pubitemid 40552825)
-
(2005)
Drug Discovery Today
, vol.10
, Issue.8
, pp. 578-585
-
-
Adell, A.1
Castro, E.2
Celada, P.3
Bortolozzi, A.4
Pazos, A.5
Artigas, F.6
-
2
-
-
0025255854
-
Cloning, functional expression, and mRNA tissue distribution of the rat 5-hydroxytryptamine 1a receptor gene
-
Albert, P.R., Zhou, Q.Y., Van Tol, H.H., Bunzow, J.R., and Civelli, O. (1990). Cloning, functional expression, and mRNA tissue distribution of the rat 5-hydroxytryptamine 1a receptor gene. J. Biol. Chem. 265, 5825-5832.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 5825-5832
-
-
Albert, P.R.1
Zhou, Q.Y.2
Van Tol, H.H.3
Bunzow, J.R.4
Civelli, O.5
-
3
-
-
33745741107
-
+ channel involved in polymodal pain perception
-
DOI 10.1038/sj.emboj.7601116, PII 7601116
-
Alloui, A., Zimmermann, K., Mamet, J., Duprat, F., Noel, J., Chemin, J., Guy, N., Blondeau, N., Voilley, N., Rubat-Coudert, C., et al. (2006). TREK-1, a K+ channel involved in polymodal pain perception. EMBO J. 25, 2368-2376. (Pubitemid 44012220)
-
(2006)
EMBO Journal
, vol.25
, Issue.11
, pp. 2368-2376
-
-
Alloui, A.1
Zimmermann, K.2
Mamet, J.3
Duprat, F.4
Noel, J.5
Chemin, J.6
Guy, N.7
Blondeau, N.8
Voilley, N.9
Rubat-Coudert, C.10
Borsotto, M.11
Romey, G.12
Heurteaux, C.13
Reeh, P.14
Eschalier, A.15
Lazdunski, M.16
-
4
-
-
0004235298
-
-
American Psychiatric Association, Fourth Edition, Text Revision. (Arlington, VA, USA: American Psychiatric Association).
-
American Psychiatric Association (2000). Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. (Arlington, VA, USA: American Psychiatric Association).
-
(2000)
Diagnostic and Statistical Manual of Mental Disorders
-
-
-
5
-
-
0035669353
-
Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims
-
DOI 10.1016/S0893-133X(01)00310-4, PII S0893133X01003104
-
Arango, V., Underwood, M., Boldrini, M., Tamir, H., Kassir, S., Hsiung, S., Chen, J., and Mann, J. (2001). Serotonin 1a receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims. Neuropsychopharmacology 25, 892-903. (Pubitemid 34031894)
-
(2001)
Neuropsychopharmacology
, vol.25
, Issue.6
, pp. 892-903
-
-
Arango, V.1
Underwood, M.D.2
Boldrini, M.3
Tamir, H.4
Kassir, S.A.5
Hsiung, S.-C.6
Chen, J.J.-X.7
Mann, J.J.8
-
6
-
-
0027163303
-
5-HT and antidepressants: New views from microdialysis studies [1]
-
Artigas, F. (1993). 5-HT and antidepressants: new views from microdialysis studies. Trends Pharmacol. Sci. 14, 262. (Pubitemid 23204242)
-
(1993)
Trends in Pharmacological Sciences
, vol.14
, Issue.7
, pp. 262
-
-
Artigas, F.1
-
7
-
-
0033777788
-
Altered serotonin and dopamine metabolism in the CNS of serotonin 5-HT 1A or 5-HT1B receptor knockout mice
-
Ase, A.R., Reader, T.A., Hen, R., Riad, M., and Descarries, L. (2000). Altered serotonin and dopamine metabolism in the CNS of serotonin 5-HT 1A or 5-HT1B receptor knockout mice. J. Neurochem. 75, 2415-2426.
-
(2000)
J. Neurochem.
, vol.75
, pp. 2415-2426
-
-
Ase, A.R.1
Reader, T.A.2
Hen, R.3
Riad, M.4
Descarries, L.5
-
8
-
-
56249145659
-
The cannabinoid CB1 receptor and the endocannabinoid anandamide: Possible antidepressant targets
-
Bambico, F.R. and Gobbi, G. (2008). The cannabinoid CB1 receptor and the endocannabinoid anandamide: possible antidepressant targets. Expert Opin. Ther. Targets 12, 1347-1366.
-
(2008)
Expert Opin. Ther. Targets
, vol.12
, pp. 1347-1366
-
-
Bambico, F.R.1
Gobbi, G.2
-
9
-
-
35548980029
-
Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex
-
DOI 10.1523/JNEUROSCI.1636-07.2007
-
Bambico, F.R., Katz, N., Debonnel, G., and Gobbi, G. (2007). Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex. J. Neurosci. 27, 11700-11711. (Pubitemid 350006914)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.43
, pp. 11700-11711
-
-
Bambico, F.R.1
Katz, N.2
Debonnel, G.3
Gobbi, G.4
-
10
-
-
77955716188
-
Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus
-
Bambico, F., Cassano, T., Dominguez-Lopez, S., Katz, N., Walker, C., Piomelli, D., and Gobbi, G. (2010). Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus. Neuropsychopharmacology 35, 2083-2100.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 2083-2100
-
-
Bambico, F.1
Cassano, T.2
Dominguez-Lopez, S.3
Katz, N.4
Walker, C.5
Piomelli, D.6
Gobbi, G.7
-
11
-
-
0031978809
-
Altered brain serotonin homeostasis and locomotor insensitivity to 3,4- methylenedioxymethamphetamine ('ecstasy') in serotonin transporter-deficient mice
-
Bengel, D., Murphy, D.L., Andrews, A.M., Wichems, C.H., Feltner, D., Heils, A., Mössner, R., Westphal, H., and Lesch, K.-P. (1998). Altered brain serotonin homeostasis and locomotor insensitivity to 3,4- methylenedioxymethamphetamine ( " ecstasy " ) in serotonin transporter-deficient mice. Mol. Pharmacol. 53, 649-655. (Pubitemid 28196486)
-
(1998)
Molecular Pharmacology
, vol.53
, Issue.4
, pp. 649-655
-
-
Bengel, D.1
Murphy, D.L.2
Andrews, A.M.3
Wichems, C.H.4
Feltner, D.5
Heils, A.6
Mossner, R.7
Westphal, H.8
Lesch, K.-P.9
-
12
-
-
2042542084
-
11C]WAY-100635
-
DOI 10.1038/sj.mp.4001401
-
Bhagwagar, Z., Rabiner, E., Sargent, P., Grasby, P., and Cowen, P. (2004). Persistent reduction in brain serotonin 1A receptor binding in recovered depressed men measured by positron emission tomography with [11C]WAY-100635. Mol. Psychiatry 9, 386-392. (Pubitemid 38534699)
-
(2004)
Molecular Psychiatry
, vol.9
, Issue.4
, pp. 386-392
-
-
Bhagwagar, Z.1
Rabiner, E.A.2
Sargent, P.A.3
Grasby, P.M.4
Cowen, P.J.5
-
13
-
-
0028287265
-
Current advances and trends in the treatment of depression
-
DOI 10.1016/0165-6147(94)90315-8
-
Blier, P. and de Montigny, C. (1994). Current advances and trends in the treatment of depression. Trends Pharmacol. Sci. 15, 220-226. (Pubitemid 24210726)
-
(1994)
Trends in Pharmacological Sciences
, vol.15
, Issue.7
, pp. 220-226
-
-
Blier, P.1
De Montigny, C.2
-
14
-
-
53449091766
-
5-HT(4) receptors: History, molecular pharmacology and brain functions
-
Bockaert, J., Claeysen, S., Compan, V., and Dumuis, A. (2008). 5-HT(4) receptors: history, molecular pharmacology and brain functions. Neuropharmacology 55, 922-931.
-
(2008)
Neuropharmacology
, vol.55
, pp. 922-931
-
-
Bockaert, J.1
Claeysen, S.2
Compan, V.3
Dumuis, A.4
-
15
-
-
79953677455
-
5-HT(4) receptors, a place in the sun: Act two
-
Bockaert, J., Claeysen, S., Compan, V., and Dumuis, A. (2011). 5-HT(4) receptors, a place in the sun: act two. Curr. Opin. Pharmacol. 11, 87-93.
-
(2011)
Curr. Opin. Pharmacol.
, vol.11
, pp. 87-93
-
-
Bockaert, J.1
Claeysen, S.2
Compan, V.3
Dumuis, A.4
-
16
-
-
0024494969
-
A comparison of the effects of diazepam versus several typical and atypical anti-depressant drugs in an animal model of anxiety
-
DOI 10.1007/BF00442264
-
Bodnoff, S.R., Suranyi-Cadotte, B., Quirion, R., and Meaney, M.J. (1989). A comparision of the effects of diazepam versus several typical and atypical anti-depressant drugs in an animal model of anxiety. Psychopharmacol. (Berl.) 97, 277-279. (Pubitemid 19040176)
-
(1989)
Psychopharmacology
, vol.97
, Issue.2
, pp. 277-279
-
-
Bodnoff, S.R.1
Suranyi-Cadotte, B.2
Quirion, R.3
Meaney, M.J.4
-
17
-
-
39049168148
-
Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides
-
DOI 10.1016/j.jpsychires.2007.05.004, PII S0022395607000908
-
Boldrini, M., Underwood, M.D., Mann, J.J., and Arango, V. (2008). Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides. J. Psychiatr. Res. 42, 433-442. (Pubitemid 351240919)
-
(2008)
Journal of Psychiatric Research
, vol.42
, Issue.6
, pp. 433-442
-
-
Boldrini, M.1
Underwood, M.D.2
Mann, J.J.3
Arango, V.4
-
18
-
-
0034054957
-
4 receptor mRNA and ligand binding sites in the post-mortem human brain
-
DOI 10.1002/(SICI)1098-2396(200004)36:1<35::AID-SYN4>3.0.CO;2-Y
-
Bonaventure, P., Hall, H., Gommeren, W., Cras, P., Langlois, X., Jurzak, M., and Leysen, J.E. (2000). Mapping of serotonin 5-HT(4) receptor mRNA and ligand binding sites in the post-mortem human brain. Synapse 36, 35-46. (Pubitemid 30134123)
-
(2000)
Synapse
, vol.36
, Issue.1
, pp. 35-46
-
-
Bonaventure, P.1
Hall, H.2
Gommeren, W.3
Cras, P.4
Langlois, X.5
Jurzak, M.6
Leysen, J.E.7
-
19
-
-
1642397405
-
1A receptor knockout mice
-
Bortolozzi, A., Amargós-Bosch, M., Toth, M., Artigas, F., and Adell, A. (2004). In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT 1A receptor knockout mice. J. Neurochem. 88, 1373-1379. (Pubitemid 38366912)
-
(2004)
Journal of Neurochemistry
, vol.88
, Issue.6
, pp. 1373-1379
-
-
Bortolozzi, A.1
Amargos-Bosch, M.2
Toth, M.3
Artigas, F.4
Adell, A.5
-
20
-
-
0034653187
-
Substance P (NK1) receptors in the cingulate cortex in unipolar and bipolar mood disorder and schizophrenia
-
DOI 10.1016/S0006-3223(99)00264-4, PII S0006322399002644
-
Burnet, P.W.J. and Harrison, P.J. (2000). Substance P (NK1) receptors in the cingulate cortex in unipolar and bipolar mood disorder and schizophrenia. Biol. Psychiatry 47, 80-83. (Pubitemid 30016083)
-
(2000)
Biological Psychiatry
, vol.47
, Issue.1
, pp. 80-83
-
-
Burnet, P.W.J.1
Harrison, P.J.2
-
21
-
-
41449111073
-
Identifying Molecular Substrates in a Mouse Model of the Serotonin Transporter x Environment Risk Factor for Anxiety and Depression
-
DOI 10.1016/j.biopsych.2007.08.013, PII S0006322307008219
-
Carola, V., Frazzetto, G., Pascucci, T., Audero, E., Puglisi-Allegra, S., Cabib, S., Lesch, K.-P., and Gross, C. (2008). Identifying molecular substrates in a mouse model of the serotonin transporter x environment risk factor for anxiety and depression. Biol. Psychiatry 63, 840-846. (Pubitemid 351458447)
-
(2008)
Biological Psychiatry
, vol.63
, Issue.9
, pp. 840-846
-
-
Carola, V.1
Frazzetto, G.2
Pascucci, T.3
Audero, E.4
Puglisi-Allegra, S.5
Cabib, S.6
Lesch, K.-P.7
Gross, C.8
-
22
-
-
0037624040
-
Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
-
DOI 10.1126/science.1083968
-
Caspi, A., Sugden, K., Moffitt, T.E., Taylor, A., Craig, I.W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., et al. (2003) Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301, 386-389. (Pubitemid 36877077)
-
(2003)
Science
, vol.301
, Issue.5631
, pp. 386-389
-
-
Caspi, A.1
Sugden, K.2
Moffitt, T.E.3
Taylor, A.4
Craig, I.W.5
Harrington, H.6
McClay, J.7
Mill, J.8
Martin, J.9
Braithwaite, A.10
Poulton, R.11
-
23
-
-
77951854270
-
Genetic sensitivity to the environment: The case of the serotonin transporter gene and its implications for studying complex diseases and traits
-
Caspi, A., Hariri, A.R., Holmes, A., Uher, R., and Moffitt, T.E. (2010). Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am. J. Psychiatry 167, 509-527.
-
(2010)
Am. J. Psychiatry
, vol.167
, pp. 509-527
-
-
Caspi, A.1
Hariri, A.R.2
Holmes, A.3
Uher, R.4
Moffitt, T.E.5
-
24
-
-
79952282058
-
Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolasedeficient mice
-
Cassano, T., Gaetani, S., Macheda, T., Laconca, L., Romano, A., Morgese, M., Cimmino, C., Chiarotti, F., Bambico, F., Gobbi, G., et al. (2011). Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolasedeficient mice. Psychopharmacol. (Berl.) 214, 465-476.
-
(2011)
Psychopharmacol. (Berl.)
, vol.214
, pp. 465-476
-
-
Cassano, T.1
Gaetani, S.2
MacHeda, T.3
Laconca, L.4
Romano, A.5
Morgese, M.6
Cimmino, C.7
Chiarotti, F.8
Bambico, F.9
Gobbi, G.10
-
25
-
-
79959542106
-
Rodent models of depression: Forced swim and tail suspension behavioral despair tests in rats and mice
-
Chapter 8, Unit 8. 10A
-
Castagne, V., Moser, P., Roux, S., and Porsolt, R.D. (2011). Rodent models of depression: forced swim and tail suspension behavioral despair tests in rats and mice. Curr. Protoc. Neurosci. Chapter 8, Unit 8. 10A.
-
(2011)
Curr. Protoc. Neurosci.
-
-
Castagne, V.1
Moser, P.2
Roux, S.3
Porsolt, R.D.4
-
26
-
-
36048995288
-
Efficacy and safety of the weight-loss drug rimonabant: A meta-analysis of randomised trials
-
DOI 10.1016/S0140-6736(07)61721-8, PII S0140673607617218
-
Christensen, R., Kristensen, P.K., Bartels, E.M., Bliddal, H., and Astrup, A. (2007). Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials. Lancet 370, 1706-1713. (Pubitemid 350100788)
-
(2007)
Lancet
, vol.370
, Issue.9600
, pp. 1706-1713
-
-
Christensen, R.1
Kristensen, P.K.2
Bartels, E.M.3
Bliddal, H.4
Astrup, A.5
-
27
-
-
9144257880
-
4 Receptor Knock-Out Mice
-
DOI 10.1523/JNEUROSCI.2806-03.2004
-
Compan, V., Zhou, M., Grailhe, R., Gazzara, R.A., Martin, R., Gingrich, J., Dumuis, A., Brunner, D., Bockaert, J., and Hen, R. (2004). Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice. J. Neurosci. 24, 412-419. (Pubitemid 38112372)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.2
, pp. 412-419
-
-
Compan, V.1
Zhou, M.2
Grailhe, R.3
Gazzara, R.A.4
Martin, R.5
Gingrich, J.6
Dumuis, A.7
Brunner, D.8
Bockaert, J.9
Hen, R.10
-
28
-
-
33747613061
-
4 receptor knock-out mouse
-
DOI 10.1111/j.1460-9568.2006.04943.x
-
Conductier, G., Dusticier, N., Lucas, G., Cote, F., Debonnel, G., Daszuta, A., Dumuis, A., Nieoullon, A., Hen, R., Bockaert, J., et al. (2006). Adaptive changes in serotonin neurons of the raphe nuclei in 5-HT(4) receptor knock-out mouse. Eur. J. Neurosci. 24, 1053-1062. (Pubitemid 44268136)
-
(2006)
European Journal of Neuroscience
, vol.24
, Issue.4
, pp. 1053-1062
-
-
Conductier, G.1
Dusticier, N.2
Lucas, G.3
Cote, F.4
Debonnel, G.5
Daszuta, A.6
Dumuis, A.7
Nieoullon, A.8
Hen, R.9
Bockaert, J.10
Compan, V.11
-
29
-
-
0035869610
-
1A receptor-mediated regulation of dorsal raphe and hippocampal cell activity
-
Cour, C.M.l., Boni, C., Hanoun, N.M., Lesch, K.-P., Hamon, M., and Lanfumey, L. (2001). Functional consequences of 5-HT transporter gene disruption on 5-HT 1A receptor-mediated regulation of dorsal raphe and hippocampal cell activity. J. Neurosci. 21, 2178-2185. (Pubitemid 32221400)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.6
, pp. 2178-2185
-
-
La Cour, C.M.1
Boni, C.2
Hanoun, N.3
Lesch, K.-P.4
Hamon, M.5
Lanfumey, L.6
-
30
-
-
0029904838
-
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
-
DOI 10.1038/384083a0
-
Cravatt, B.F., Giang, D.K., Mayfield, S.P., Boger, D.L., Lerner, R.A., and Gilula, N.B. (1996). Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature 384, 83-87. (Pubitemid 26374593)
-
(1996)
Nature
, vol.384
, Issue.6604
, pp. 83-87
-
-
Cravatt, B.F.1
Giang, D.K.2
Mayfield, S.P.3
Boger, D.L.4
Lerner, R.A.5
Gilula, N.B.6
-
31
-
-
0035979244
-
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
-
DOI 10.1073/pnas.161191698
-
Cravatt, B.F., Demarest, K., Patricelli, M.P., Bracey, M.H., Giang, D.K., Martin, B.R., and Lichtman, A.H. (2001). Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proc. Nat. Acad. Sci. USA 98, 9371-9376. (Pubitemid 32743923)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.16
, pp. 9371-9376
-
-
Cravatt, B.F.1
Demarest, K.2
Patricelli, M.P.3
Bracey, M.H.4
Giang, D.K.5
Martin, B.R.6
Lichtman, A.H.7
-
32
-
-
26044460006
-
Model organisms: The ascent of mouse: Advances in modelling human depression and anxiety
-
DOI 10.1038/nrd1825, PII N1825
-
Cryan, J. and Holmes, A. (2005). The ascent of mouse: advances in modelling human depression and anxiety. Nat. Rev. Drug Discov. 4, 775-790. (Pubitemid 43090498)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.9
, pp. 775-790
-
-
Cryan, J.F.1
Holmes, A.2
-
33
-
-
12344315947
-
Antidepressant-like effects of neurokinin receptor antagonists in the forced swim test in the rat
-
DOI 10.1016/j.ejphar.2004.11.024, PII S0014299904013226
-
Dableh, L., Yashpal, K., Rochford, J., and Henry, J. (2005). Anti depressant-like effects of neurokinin receptor antagonists in the forced swim test in the rat. Eur. J. Pharmacol. 507, 99-105. (Pubitemid 40126845)
-
(2005)
European Journal of Pharmacology
, vol.507
, Issue.1-3
, pp. 99-105
-
-
Dableh, L.J.1
Yashpal, K.2
Rochford, J.3
Henry, J.L.4
-
34
-
-
0001989283
-
Evidence for the existence of monoamine-containing neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brain stem neurons
-
Dahlstroem, A. and Fuxe, K. (1964). Evidence for the existence of monoamine-containing neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brain stem neurons. Acta Physiol. Scand. 62(Suppl. 232), 1-55.
-
(1964)
Acta Physiol. Scand.
, vol.62
, Issue.SUPPL. 232
, pp. 1-55
-
-
Dahlstroem, A.1
Fuxe, K.2
-
35
-
-
2142758070
-
Substance P: Structure, function, and therapeutics
-
DOI 10.2174/1568026043451636
-
Datar, P., Srivastava, S., Coutinho, E., and Govil, G. (2004). Substance P: structure, function, and therapeutics. Curr. Top. Med. Chem. 4, 75-103. (Pubitemid 38849358)
-
(2004)
Current Topics in Medicinal Chemistry
, vol.4
, Issue.1
, pp. 75-103
-
-
Datar, P.1
Srivastava, S.2
Coutinho, E.3
Govil, G.4
-
36
-
-
0032588747
-
4 receptor or the serotonin transporter in the dorsolateral prefrontal cortex from subjects with schizophrenia
-
DOI 10.1016/S0197-0186(98)00074-6, PII S0197018698000746
-
Dean, B., Tomaskovic-Crook, E., Opeskin, K., Keks, N., and Copolov, D. (1999). No change in the density of the serotonin-1A receptor, the serotonin-4 receptor or the serotonin transporter in the dorsolateral prefrontal cortex from subjects with schizophrenia. Neurochem. Int. 34, 109-115. (Pubitemid 29148374)
-
(1999)
Neurochemistry International
, vol.34
, Issue.2
, pp. 109-115
-
-
Dean, B.1
Tomaskovic-Crook, E.2
Opeskin, K.3
Keks, N.4
Copolov, D.5
-
37
-
-
0032568444
-
Altered nociception, analgesia and aggression in mice lacking the receptor for substance P
-
DOI 10.1038/32904
-
De Felipe, C., Herrero, J., O'Brien, J., Palmer, J., Doyle, C., Smith, A., Laird, J., Belmonte, C., Cervero, F., and Hunt, S. (1998). Altered nociception, analgesia and aggression in mice lacking the receptor for substance P. Nature 392, 394-397. (Pubitemid 28168736)
-
(1998)
Nature
, vol.392
, Issue.6674
, pp. 394-397
-
-
De Felipe, C.1
Herrero, J.F.2
O'Brien, J.A.3
Palmer, J.A.4
Doyle, C.A.5
Smith, A.J.H.6
Laird, J.M.A.7
Belmonte, C.8
Cervero, F.9
Hunt, S.P.10
-
38
-
-
34347232304
-
+ channels in the entorhinal cortex
-
DOI 10.1124/mol.107.034389
-
Deng, P.-Y., Poudel, S.K.S., Rojanathammanee, L., Porter, J.E., and Lei, S. (2007). Serotonin inhibits neuronal excitability by activating two-pore domain K+ channels in the entorhinal cortex. Mol. Pharmacol. 72, 208-218. (Pubitemid 46998540)
-
(2007)
Molecular Pharmacology
, vol.72
, Issue.1
, pp. 208-218
-
-
Deng, P.-Y.1
Poudel, S.K.S.2
Rojanathammanee, L.3
Porter, J.E.4
Lei, S.5
-
39
-
-
0019967379
-
The serotonin neurons in nucleus raphe dorsalis of adult rat: A light and electron microscope radioautographic study
-
DOI 10.1002/cne.902070305
-
Descarries, L., Watkins, K.C., Garcia, S., and Beaudet, A. (1982). The serotonin neurons in nucleus raphe dorsalis of adult rat: a light and electron microscope radioautographic study. J. Comp. Neurol. 207, 239-254. (Pubitemid 12081283)
-
(1982)
Journal of Comparative Neurology
, vol.207
, Issue.3
, pp. 239-254
-
-
Descarries, L.1
Watkins, K.2
Garcia, S.3
Beaudet, A.4
-
40
-
-
79951829325
-
Discovery and biological characterization of (2r,4s)-1'-acetyl-n-{(1r)-1- [3,5-bis(trifluoromethyl) phenyl] ethyl}-2-(4-fluoro-2-methylphenyl)-n-methyl-4, 4'-bipiperidine- 1-carboxamide as a new potent and selective neurokinin 1 (NK1) receptor antagonist clinical candidate
-
Di Fabio, R., Alvaro, G., Griffante, C., Pizzi, D.A., Donati, D., Mattioli, M., Cimarosti, Z., Guercio, G., Marchioro, C., Provera, S., et al. (2011). Discovery and biological characterization of (2r,4s)-1'-acetyl-n-{(1r)- 1-[3,5-bis(trifluoromethyl) phenyl] ethyl}-2-(4-fluoro-2-methylphenyl)-n-methyl- 4,4'-bipiperidine- 1-carboxamide as a new potent and selective neurokinin 1 (NK1) receptor antagonist clinical candidate. J. Med. Chem. 54, 1071-1079.
-
(2011)
J. Med. Chem.
, vol.54
, pp. 1071-1079
-
-
Di Fabio, R.1
Alvaro, G.2
Griffante, C.3
Pizzi, D.A.4
Donati, D.5
Mattioli, M.6
Cimarosti, Z.7
Guercio, G.8
Marchioro, C.9
Provera, S.10
-
41
-
-
76249123411
-
Variation in TREK1 gene linked to depression-resistant phenotype is associated with potentiated neural responses to rewards in humans
-
Dillon, D.G., Bogdan, R., Fagerness, J., Holmes, A.J., Perlis, R.H., and Pizzagalli, D.A. (2010). Variation in TREK1 gene linked to depression-resistant phenotype is associated with potentiated neural responses to rewards in humans. Hum. Brain Mapp. 31, 210-221.
-
(2010)
Hum. Brain Mapp.
, vol.31
, pp. 210-221
-
-
Dillon, D.G.1
Bogdan, R.2
Fagerness, J.3
Holmes, A.J.4
Perlis, R.H.5
Pizzagalli, D.A.6
-
42
-
-
84862147652
-
Short term effects of melatonin and pinealectomy on serotonergic neuronal activity across the light-dark cycle
-
Domínguez-López, S., Mahar, I., Bambico, F.R., Labonte, B., Ochoa-Sanchez, R., Leyton, M., and Gobbi, G. (2012) Short term effects of melatonin and pinealectomy on serotonergic neuronal activity across the light-dark cycle. J. Psychopharmacol. 26, 830-844.
-
(2012)
J. Psychopharmacol.
, vol.26
, pp. 830-844
-
-
Domínguez-López, S.1
Mahar, I.2
Bambico, F.R.3
Labonte, B.4
Ochoa-Sanchez, R.5
Leyton, M.6
Gobbi, G.7
-
43
-
-
34848912806
-
Serotonin-1A receptor imaging in recurrent depression: Replication and literature review
-
DOI 10.1016/j.nucmedbio.2007.06.008, PII S0969805107001692
-
Drevets, W., Thase, M., Moses-Kolko, E., Price, J., Frank, E., Kupfer, D., and Mathis, C. (2007). Serotonin-1A receptor imaging in recurrent depression: replication and literature review. Nucl. Med. Biol. 34, 865-877. (Pubitemid 47505401)
-
(2007)
Nuclear Medicine and Biology
, vol.34
, Issue.7
, pp. 865-877
-
-
Drevets, W.C.1
Thase, M.E.2
Moses-Kolko, E.L.3
Price, J.4
Frank, E.5
Kupfer, D.J.6
Mathis, C.7
-
44
-
-
0032494704
-
A new perspective on cannabinoid signalling: Complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain
-
DOI 10.1098/rspb.1998.0543
-
Egertová, M., Giang, D.K., Cravatt, B.F., and Elphick, M.R. (1998). A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain. Proc. Roy. Soc. Biol. 265, 2081-2085. (Pubitemid 28502544)
-
(1998)
Proceedings of the Royal Society B: Biological Sciences
, vol.265
, Issue.1410
, pp. 2081-2085
-
-
Egertova, M.1
Giang, D.K.2
Cravatt, B.F.3
Elphick, M.R.4
-
45
-
-
0033915750
-
Altered expression and functions of serotonin 5-HT(1A) and 5-HT(1B) receptors in knock-out mice lacking the 5-HT transporter
-
DOI 10.1046/j.1460-9568.2000.00126.x
-
Fabre, V., Beaufour, C., Evrard, A., Rioux, A., Hanoun, N., Lesch, K.P., Murphy, D.L., Lanfumey, L., Hamon, M., and Martres, M.P. (2000). Altered expression and functions of serotonin 5-HT 1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter. Eur. J. Neurosci. 12, 2299-2310. (Pubitemid 30497028)
-
(2000)
European Journal of Neuroscience
, vol.12
, Issue.7
, pp. 2299-2310
-
-
Fabre, V.1
Beaufour, C.2
Evrard, A.3
Rioux, A.4
Hanoun, N.5
Lesch, K.P.6
Murphy, D.L.7
Lanfumey, L.8
Hamon, M.9
Martres, M.-P.10
-
46
-
-
0023786564
-
The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT 1A receptor
-
Fargin, A., Raymond, J., Lohse, M., Kobilka, B., Caron, M., and Lefkowitz, R. (1988). The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT 1A receptor. Nature 335, 358-360.
-
(1988)
Nature
, vol.335
, pp. 358-360
-
-
Fargin, A.1
Raymond, J.2
Lohse, M.3
Kobilka, B.4
Caron, M.5
Lefkowitz, R.6
-
47
-
-
0030451916
-
Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel
-
Fink, M., Duprat, F., Lesage, F., Reyes, R., Romey, G., Heurteaux, C., and Lazdunski, M. (1996). Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel. EMBO J. 15, 6854-6862.
-
(1996)
EMBO J.
, vol.15
, pp. 6854-6862
-
-
Fink, M.1
Duprat, F.2
Lesage, F.3
Reyes, R.4
Romey, G.5
Heurteaux, C.6
Lazdunski, M.7
-
48
-
-
0026503927
-
Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor
-
Fong, T.M., Anderson, S.A., Yu, H., Huang, R.R., and Strader, C.D. (1992). Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor. Mol. Pharmacol. 41, 24-30.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 24-30
-
-
Fong, T.M.1
Anderson, S.A.2
Yu, H.3
Huang, R.R.4
Strader, C.D.5
-
49
-
-
0037661996
-
Role of endogenous cannabinoids in synaptic signaling
-
Freund, T.F., Katona, I., and PiomelliI, D. (2003). Role of endogenous cannabinoids in synaptic signaling. Physiol. Rev. 83, 1017-1066. (Pubitemid 36828930)
-
(2003)
Physiological Reviews
, vol.83
, Issue.3
, pp. 1017-1066
-
-
Freund, T.F.1
Katona, I.2
Piomelli, D.3
-
50
-
-
77953356592
-
Modulation of the CRH system by substance P/NKA in an animal model of depression
-
Frisch, P., Bilkei-Gorzo, A., Racz, I., and Zimmer, A. (2010). Modulation of the CRH system by substance P/NKA in an animal model of depression. Behav. Brain Res. 213, 103-108.
-
(2010)
Behav. Brain Res.
, vol.213
, pp. 103-108
-
-
Frisch, P.1
Bilkei-Gorzo, A.2
Racz, I.3
Zimmer, A.4
-
51
-
-
0035887916
-
1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization
-
Froger, N., Gardier, A.M., Moratalla, R., Alberti, I., Lena, I., Boni, C., De Felipe, C., Rupniak, N.M.J., Hunt, S.P., Jacquot, C., et al. (2001). 5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization. J. Neurosci. 21, 8188-8197. (Pubitemid 32952774)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.20
, pp. 8188-8197
-
-
Froger, N.1
Gardier, A.M.2
Moratalla, R.3
Alberti, I.4
Lena, I.5
Boni, C.6
De Felipe, C.7
Rupniak, N.M.J.8
Hunt, S.P.9
Jacquot, C.10
Hamon, M.11
Lanfumey, L.12
-
52
-
-
40849106521
-
Neurokinin 1 receptor antagonism as a possible therapy for alcoholism
-
DOI 10.1126/science.1153813
-
George, D.T., Gilman, J., Hersh, J., Thorsell, A., Herion, D., Geyer, C., Peng, X., Kielbasa, W., Rawlings, R., Brandt, J.E., et al. (2008). Neurokinin 1 receptor antagonism as a possible therapy for alcoholism. Science 319, 1536-1539. (Pubitemid 351398184)
-
(2008)
Science
, vol.319
, Issue.5869
, pp. 1536-1539
-
-
George, D.T.1
Gilman, J.2
Hersh, J.3
Thorsell, A.4
Herion, D.5
Geyer, C.6
Peng, X.7
Kielbasa, W.8
Rawlings, R.9
Brandt, J.E.10
Gehlert, D.R.11
Tauscher, J.T.12
Hunt, S.P.13
Hommer, D.14
Heilig, M.15
-
53
-
-
85047696280
-
Elevated cerebrospinal fluid substance P concentrations in posttraumatic stress disorder and major depression
-
DOI 10.1176/appi.ajp.163.4.637
-
Geracioti, T.D., Jr., Carpenter, L.L., Owens, M.J., Baker, D.G., Ekhator, N.N., Horn, P.S., Strawn, J.R., Sanacora, G., Kinkead, B., Price, L.H., et al. (2006). Elevated cerebrospinal fluid substance P concentrations in posttraumatic stress disorder and major depression. Am. J. Psychiatry 163, 637-643. (Pubitemid 44464573)
-
(2006)
American Journal of Psychiatry
, vol.163
, Issue.4
, pp. 637-643
-
-
Geracioti Jr., T.D.1
Carpenter, L.L.2
Owens, M.J.3
Baker, D.G.4
Ekhator, N.N.5
Horn, P.S.6
Strawn, J.R.7
Sanacora, G.8
Kinkead, B.9
Price, L.H.10
Nemeroff, C.B.11
-
54
-
-
0028978023
-
The 5-HT4 receptor: Molecular cloning and pharmacological characterization of two splice variants
-
Gerald, C., Adham, N., Kao, H.T., Olsen, M.A., Laz, T.M., Schechter, L.E., Bard, J.A., Vaysse, P.J., Hartig, P.R., Branchek, T.A., et al. (1995). The 5-HT4 receptor: molecular cloning and pharmacological characterization of two splice variants. EMBO J. 14, 2806-2815.
-
(1995)
EMBO J.
, vol.14
, pp. 2806-2815
-
-
Gerald, C.1
Adham, N.2
Kao, H.T.3
Olsen, M.A.4
Laz, T.M.5
Schechter, L.E.6
Bard, J.A.7
Vaysse, P.J.8
Hartig, P.R.9
Branchek, T.A.10
-
55
-
-
0035122950
-
Modifications of the serotonergic system in mice lacking serotonin transporters: An in vivo electrophysiological study
-
Gobbi, G., Murphy, D.L., Lesch, K.-P., and Blier, P. (2001). Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study. J. Pharmacol. Exp. Ther. 296, 987-995. (Pubitemid 32187374)
-
(2001)
Journal of Pharmacology and Experimental Therapeutics
, vol.296
, Issue.3
, pp. 987-995
-
-
Gobbi, G.1
Murphy, D.L.2
Lesch, K.-P.3
Blier, P.4
-
56
-
-
29444460231
-
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis
-
DOI 10.1073/pnas.0509591102
-
Gobbi, G., Bambico, F.R., Mangieri, R., Bortolato, M., Campolongo, P., Solinas, M., Cassano, T., Morgese, M.G., Debonnel, G., Duranti, A., et al. (2005). Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proc. Nat. Acad. Sci. USA 102, 18620-18625. (Pubitemid 43011275)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.51
, pp. 18620-18625
-
-
Gobbi, G.1
Bambico, F.R.2
Mangieri, R.3
Bortolato, M.4
Campolongo, P.5
Solinas, M.6
Cassano, T.7
Morgese, M.G.8
Debonnel, G.9
Duranti, A.10
Tontini, A.11
Tarzia, G.12
Mor, M.13
Trezza, V.14
Goldberg, S.R.15
Cuomo, V.16
Piomelli, D.17
-
57
-
-
33847178396
-
Neurokinin 1 receptor antagonism requires norepinephrine to increase serotonin function
-
Gobbi, G., Cassano, T., Radja, F., Morgese, M., Cuomo, V., Santarelli, L., Hen, R., and Blier, P. (2007). Neurokinin 1 receptor antagonism requires norepinephrine to increase serotonin function. Eur. Neuropsychopharmacol. 17, 328-338.
-
(2007)
Eur. Neuropsychopharmacol.
, vol.17
, pp. 328-338
-
-
Gobbi, G.1
Cassano, T.2
Radja, F.3
Morgese, M.4
Cuomo, V.5
Santarelli, L.6
Hen, R.7
Blier, P.8
-
58
-
-
0033525170
-
Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets
-
DOI 10.1002/(SICI)1096-8628(19990205)88:1<83::AID-AJMG15>3.0.CO;2-0
-
Greenberg, B.D., Tolliver, T.J., Huang, S.-J., Li, Q., Bengel, D., and Murphy, D.L. (1999). Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets. Am. J. Med. Genet. 88, 83-87. (Pubitemid 29075327)
-
(1999)
American Journal of Medical Genetics - Neuropsychiatric Genetics
, vol.88
, Issue.1
, pp. 83-87
-
-
Greenberg, B.D.1
Tolliver, T.J.2
Huang, S.-J.3
Li, Q.4
Bengel, D.5
Murphy, D.L.6
-
59
-
-
0037187193
-
1A receptor acts during development to establish normal anxiety-like behaviour in the adult
-
DOI 10.1038/416396a
-
Gross, C., Zhuang, X., Stark, K., Ramboz, S., Oosting, R., Kirby, L., Santarelli, L., Beck, S., and Hen, R. (2002). Serotonin-1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature 416, 396-400. (Pubitemid 34272867)
-
(2002)
Nature
, vol.416
, Issue.6879
, pp. 396-400
-
-
Gross, C.1
Zhuang, X.2
Stark, K.3
Ramboz, S.4
Oosting, R.5
Kirby, L.6
Santarelli, L.7
Beck, S.8
Hen, R.9
-
60
-
-
84858791972
-
Altered response to the selective serotonin reuptake inhibitor escitalopram in mice heterozygous for the serotonin transporter: An electrophysiological and neurochemical study
-
Guiard, B.P., Mansari, M.E., Murphy, D.L., and Blier, P. (2012). Altered response to the selective serotonin reuptake inhibitor escitalopram in mice heterozygous for the serotonin transporter: an electrophysiological and neurochemical study. Int. J. Neuropsychopharmacol. 15, 349-361.
-
(2012)
Int. J. Neuropsychopharmacol.
, vol.15
, pp. 349-361
-
-
Guiard, B.P.1
Mansari, M.E.2
Murphy, D.L.3
Blier, P.4
-
61
-
-
33748764379
-
1A receptor knockout mice
-
DOI 10.1038/sj.npp.1301019, PII 1301019
-
Guilloux, J., David, D., Guiard, B., Chenu, F., Reperant, C., Toth, M., Bourin, M., and Gardier, A. (2006). Blockade of 5-HT 1A receptors by (+/-)-pindolol potentiates cortical 5-HT outflow, but not antidepressant-like activity of paroxetine: microdialysis and behavioral approaches in 5-HT 1A receptor knockout mice. Neuropsychopharmacology 31, 2162-2172. (Pubitemid 44413193)
-
(2006)
Neuropsychopharmacology
, vol.31
, Issue.10
, pp. 2162-2172
-
-
Guilloux, J.-P.1
David, D.J.P.2
Guiard, B.P.3
Chenu, F.4
Reperant, C.5
Toth, M.6
Bourin, M.7
Gardier, A.M.8
-
62
-
-
79958106058
-
5-HT(1A)-receptor over-expressing mice: Genotype and sex dependent responses to antidepressants in the forced swim-test
-
Gunther, L., Rothe, J., Rex, A., Voigt, J., Millan, M., Fink, H., and Bert, B. (2011). 5-HT(1A)-receptor over-expressing mice: genotype and sex dependent responses to antidepressants in the forced swim-test. Neuropharmacology 61, 433-441.
-
(2011)
Neuropharmacology
, vol.61
, pp. 433-441
-
-
Gunther, L.1
Rothe, J.2
Rex, A.3
Voigt, J.4
Millan, M.5
Fink, H.6
Bert, B.7
-
63
-
-
0035422889
-
Sustained blockade of neurokinin-1 receptors enhances serotonin neurotransmission
-
DOI 10.1016/S0006-3223(01)01162-3, PII S0006322301011623
-
Haddjeri, N. and Blier, P. (2001). Sustained blockade of neurokinin-1 receptors enhances serotonin neurotransmission. Biol. Psychiatry 50, 191-199. (Pubitemid 32763097)
-
(2001)
Biological Psychiatry
, vol.50
, Issue.3
, pp. 191-199
-
-
Haddjeri, N.1
Blier, P.2
-
64
-
-
79551686302
-
Depression and antidepressants: Insights from knockout of dopamine, serotonin or noradrenaline re-uptake transporters
-
Haenisch, B. and Bönisch, H. (2011). Depression and antidepressants: insights from knockout of dopamine, serotonin or noradrenaline re-uptake transporters. Pharmacol. Ther. 129, 352-368.
-
(2011)
Pharmacol. Ther.
, vol.129
, pp. 352-368
-
-
Haenisch, B.1
Bönisch, H.2
-
65
-
-
0036452132
-
1) in the living human brain using positron emission tomography
-
Hargreaves, R. (2002). Imaging substance P receptors (NK1) in the living human brain using positron emission tomography. J. Clin. Psychiatry 63, 18-24. (Pubitemid 35435004)
-
(2002)
Journal of Clinical Psychiatry
, vol.63
, Issue.SUPPL. 11
, pp. 18-24
-
-
Hargreaves, R.1
-
66
-
-
34247860697
-
Identification of the cannabinoid receptor type 1 in serotonergic cells of raphe nuclei in mice
-
DOI 10.1016/j.neuroscience.2007.02.021, PII S0306452207001856
-
Haring, M., Marsicano, G., Lutz, B., and Monory, K. (2007). Identification of the cannabinoid receptor type 1 in serotonergic cells of raphe nuclei in mice. Neuroscience 146, 1212-1219. (Pubitemid 46694132)
-
(2007)
Neuroscience
, vol.146
, Issue.3
, pp. 1212-1219
-
-
Haring, M.1
Marsicano, G.2
Lutz, B.3
Monory, K.4
-
67
-
-
0029895783
-
Allelic variation of human serotonin transporter gene expression
-
Heils, A., Teufel, A., Petri, S., Stober, G., Riederer, P., Bengel, D., and Lesch, K. (1996). Allelic variation of human serotonin transporter gene expression. J. Neurochem. 66, 2621-2624. (Pubitemid 26159101)
-
(1996)
Journal of Neurochemistry
, vol.66
, Issue.6
, pp. 2621-2624
-
-
Heils, A.1
Teufel, A.2
Petri, S.3
Stober, G.4
Riederer, P.5
Bengel, D.6
Lesch, K.P.7
-
68
-
-
0032410750
-
Elevated anxiety and antidepressant-like responses in serotonin 5- HT(1A) receptor mutant mice
-
DOI 10.1073/pnas.95.25.15049
-
Heisler, L.K., Chu, H.-M., Brennan, T.J., Danao, J.A., Bajwa, P., Parsons, L.H., and Tecott, L.H. (1998). Elevated anxiety and antidepressant-like responses in serotonin 5-HT 1A receptor mutant mice. Proc. Nat. Acad. Sci. USA 95, 15049-15054. (Pubitemid 29003754)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.25
, pp. 15049-15054
-
-
Heisler, L.K.1
Chu, H.-M.2
Brennan, T.J.3
Danao, J.A.4
Bajwa, P.5
Parsons, L.H.6
Tecott, L.H.7
-
69
-
-
0035804774
-
Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS
-
DOI 10.1016/S0306-4522(01)00030-6, PII S0306452201000306
-
Hervieu, G.J., Cluderay, J.E., Gray, C.W., Green, P.J., Ranson, J.L., Randall, A.D., and Meadows, H.J. (2001). Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS. Neuroscience 103, 899-919. (Pubitemid 32289303)
-
(2001)
Neuroscience
, vol.103
, Issue.4
, pp. 899-919
-
-
Hervieu, G.J.1
Cluderay, J.E.2
Gray, C.W.3
Green, P.J.4
Ranson, J.L.5
Randall, A.D.6
Meadows, H.J.7
-
70
-
-
3342981356
-
+ channel involved in neuroprotection and general anesthesia
-
DOI 10.1038/sj.emboj.7600234
-
Heurteaux, C., Guy, N., Laigle, C., Blondeau, N., Duprat, F., Mazzuca, M., Lang-Lazdunski, L., Widmann, C., Zanzouri, M., Romey, G., et al. (2004). TREK-1, a K+ channel involved in neuroprotection and general anesthesia. EMBO J. 23, 2684-2695. (Pubitemid 38988239)
-
(2004)
EMBO Journal
, vol.23
, Issue.13
, pp. 2684-2695
-
-
Heurteaux, C.1
Guy, N.2
Laigle, C.3
Blondeau, N.4
Duprat, F.5
Mazzuca, M.6
Lang-Lazdunski, L.7
Widmann, C.8
Zanzouri, M.9
Romey, G.10
Lazdunski, M.11
-
71
-
-
33748111816
-
Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype
-
DOI 10.1038/nn1749, PII NN1749
-
Heurteaux, C., Lucas, G., Guy, N., El Yacoubi, M., Thummler, S., Peng, X.D., Noble, F., Blondeau, N., Widmann, C., Borsotto, M., et al. (2006). Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype. Nat. Neurosci. 9, 1134-1141. (Pubitemid 44306306)
-
(2006)
Nature Neuroscience
, vol.9
, Issue.9
, pp. 1134-1141
-
-
Heurteaux, C.1
Lucas, G.2
Guy, N.3
El Yacoubi, M.4
Thummler, S.5
Peng, X.-D.6
Noble, F.7
Blondeau, N.8
Widmann, C.9
Borsotto, M.10
Gobbi, G.11
Vaugeois, J.-M.12
Debonnel, G.13
Lazdunski, M.14
-
72
-
-
41149130214
-
Serum endocannabinoid content is altered in females with depressive disorders: A preliminary report
-
DOI 10.1055/s-2007-993211
-
Hill, M.N., Miller, G.E., Ho, W.S., Gorzalka, B.B., and Hillard, C.J. (2008). Serum endocannabinoid content is altered in females with depressive disorders: a preliminary report. Pharmacopsychiatry 41, 48-53. (Pubitemid 351427522)
-
(2008)
Pharmacopsychiatry
, vol.41
, Issue.2
, pp. 48-53
-
-
Hill, M.N.1
Miller, G.E.2
Ho, W.-S.V.3
Gorzalka, B.B.4
Hillard, C.J.5
-
73
-
-
67650617724
-
Circulating endocannabinoids and n-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress
-
Hill, M.N., Miller, G.E., Carrier, E.J., Gorzalka, B.B., and Hillard, C.J. (2009). Circulating endocannabinoids and n-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. Psychoneuroendocrinology 34, 1257-1262.
-
(2009)
Psychoneuroendocrinology
, vol.34
, pp. 1257-1262
-
-
Hill, M.N.1
Miller, G.E.2
Carrier, E.J.3
Gorzalka, B.B.4
Hillard, C.J.5
-
74
-
-
0030852614
-
Accumulation of N-arachidonoylethanolamine (anandamide) into cerebellar granule cells occurs via facilitated diffusion
-
Hillard, C.J., Edgemond, W.S., Jarrahian, A., and Campbell, W.B. (1997). Accumulation of N-arachidonoylethanolamine (anandamide) into cerebellar granule cells occurs via facilitated diffusion. J. Neurochem. 69, 631-638 (Pubitemid 27327964)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.2
, pp. 631-638
-
-
Hillard, C.J.1
Edgemond, W.S.2
Jarrahian, A.3
Campbell, W.B.4
-
75
-
-
0036897940
-
Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter
-
DOI 10.1016/S0893-133X(02)00374-3, PII S0893133X02003743
-
Holmes, A., Yang, R.J., Murphy, D.L., and Crawley, J.N. (2002). Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter. Neuropsychopharmacology 27, 914-923. (Pubitemid 35447628)
-
(2002)
Neuropsychopharmacology
, vol.27
, Issue.6
, pp. 914-923
-
-
Holmes, A.1
Yang, R.J.2
Murphy, D.L.3
Crawley, J.N.4
-
76
-
-
33750044558
-
1A receptor knockout mice: Potential relevance to the neurobiology of autism
-
DOI 10.1111/j.1471-4159.2006.04150.x
-
Janusonis, S., Anderson, G., Shifrovich, I., and Rakic, P. (2006). Ontogeny of brain and blood serotonin levels in 5-HT receptor knockout mice: potential relevance to the neurobiology of autism. J. Neurochem. 99, 1019-1031. (Pubitemid 44583458)
-
(2006)
Journal of Neurochemistry
, vol.99
, Issue.3
, pp. 1019-1031
-
-
Janusonis, S.1
Anderson, G.M.2
Shifrovich, I.3
Rakic, P.4
-
77
-
-
35548939630
-
4 receptors is mediated by increases in CART in the nucleus accumbens
-
DOI 10.1073/pnas.0701471104
-
Jean, A., Conductier, G., Manrique, C., Bouras, C., Berta, P., Hen, R., Charnay, Y., Bockaert, J., and Compan, V. (2007). Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens. Proc. Nat. Acad. Sci. USA 104, 16335-16340. (Pubitemid 350099405)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.41
, pp. 16335-16340
-
-
Jean, A.1
Conductier, G.2
Manrique, C.3
Bouras, C.4
Berta, P.5
Hen, R.6
Charnay, Y.7
Bockaert, J.8
Compan, V.9
-
78
-
-
79952033418
-
The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: Evidence of genetic moderation
-
Karg, K., Burmeister, M., Shedden, K., and Sen, S. (2011). The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation. Arch. Gen. Psychiatry 68, 444-454.
-
(2011)
Arch. Gen. Psychiatry
, vol.68
, pp. 444-454
-
-
Karg, K.1
Burmeister, M.2
Shedden, K.3
Sen, S.4
-
79
-
-
0030915744
-
4 receptor antagonists SB 204070A and SB 207266A in rats
-
DOI 10.1016/S0028-3908(97)00037-3, PII S0028390897000373
-
Kennett, G.A., Bright, F., Trail, B., Blackburn, T.P., and Sanger, G.J. (1997). Anxiolytic-like actions of the selective 5-HT4 receptor antagonists SB 204070A and SB 207266A in rats. Neuropharmacology 36, 707-712. (Pubitemid 27272117)
-
(1997)
Neuropharmacology
, vol.36
, Issue.4-5
, pp. 707-712
-
-
Kennett, G.A.1
Bright, F.2
Trail, B.3
Blackburn, T.P.4
Sanger, G.J.5
-
80
-
-
26944447116
-
Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter
-
DOI 10.1016/j.neuropharm.2005.08.010, PII S0028390805003102, New Perspectives in Neurotransmitter Transporter Biology
-
Kim, D.-K., Tolliver, T.J., Huang, S.-J., Martin, B.J., Andrews, A.M., Wichems, C., Holmes, A., Lesch, K.-P., and Murphy, D.L. (2005). Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter. Neuropharmacology 49, 798-810. (Pubitemid 41483886)
-
(2005)
Neuropharmacology
, vol.49
, Issue.6
, pp. 798-810
-
-
Kim, D.-K.1
Tolliver, T.J.2
Huang, S.-J.3
Martin, B.J.4
Andrews, A.M.5
Wichems, C.6
Holmes, A.7
Lesch, K.-P.8
Murphy, D.L.9
-
81
-
-
0034883141
-
1B autoreceptors in different brain regions of the mouse
-
Knobelman, D.A., Hen, R., and Lucki, I. (2001). Genetic regulation of extracellular serotonin by 5-hydroxytryptamine 1A and 5-hydroxytryptamine 1B autoreceptors in different brain regions of the mouse. J. Pharmacol. Exp. Ther. 298, 1083-1091. (Pubitemid 32761924)
-
(2001)
Journal of Pharmacology and Experimental Therapeutics
, vol.298
, Issue.3
, pp. 1083-1091
-
-
Knobelman, D.A.1
Hen, R.2
Lucki, I.3
-
82
-
-
0023643263
-
An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins
-
Kobilka, B., Frielle, T., Collins, S., Yang-Feng, T., Kobilka, T., Francke, U., Lefkowitz, R., and Caron, M. (1987). An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins. Nature 329, 75-79. (Pubitemid 17125898)
-
(1987)
Nature
, vol.328
, Issue.6134
, pp. 75-79
-
-
Kobilka, B.K.1
Frielle, T.2
Collins, S.3
-
83
-
-
0032508514
-
Distinct mechanism for antidepressant activity by blockade of central substance P receptors
-
DOI 10.1126/science.281.5383.1640
-
Kramer, M.S., Cutler, N., Feighner, J., Shrivastava, R., Carman, J., Sramek, J.J., Reines, S.A., Liu, G., Snavely, D., Wyatt-Knowles, E., et al. (1998). Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science 281, 1640-1645. (Pubitemid 28435572)
-
(1998)
Science
, vol.281
, Issue.5383
, pp. 1640-1645
-
-
Kramer, M.S.1
Cutler, N.2
Feighner, J.3
Shrivastava, R.4
Carman, J.5
Sramek, J.J.6
Reines, S.A.7
Liu, G.8
Snavely, D.9
Wyatt-Knowles, E.10
Hale, J.J.11
Mills, S.G.12
MacCoss, M.13
Swain, C.J.14
Harrison, T.15
Hill, R.G.16
Hefti, F.17
Scolnick, E.M.18
Cascieri, M.A.19
Chicchi, G.G.20
Sadowski, S.21
Williams, A.R.22
Hewson, L.23
Smith, D.24
Carlson, E.J.25
Hargreaves, R.J.26
Rupniak, N.M.J.27
more..
-
84
-
-
50449086944
-
Differences in the length of the carboxyl terminus mediate functional properties of neurokinin-1 receptor
-
Lai, J.-P., Lai, S., Tuluc, F., Tansky, M.F., Kilpatrick, L.E., Leeman, S.E., and Douglas, S.D. (2008). Differences in the length of the carboxyl terminus mediate functional properties of neurokinin-1 receptor. Proc. Nat. Acad. Sci. USA 105, 12605-12610.
-
(2008)
Proc. Nat. Acad. Sci. USA
, vol.105
, pp. 12605-12610
-
-
Lai, J.-P.1
Lai, S.2
Tuluc, F.3
Tansky, M.F.4
Kilpatrick, L.E.5
Leeman, S.E.6
Douglas, S.D.7
-
85
-
-
0141758243
-
Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide
-
Lemonde, S., Turecki, G., Bakish, D., Du, L., Hrdina, P.D., Bown, C.D., Sequeira, A., Kushwaha, N., Morris, S.J., Basak, A., et al. (2003). Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide. J. Neurosci. 23, 8788-8799. (Pubitemid 37176660)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.25
, pp. 8788-8799
-
-
Lemonde, S.1
Turecki, G.2
Bakish, D.3
Du, L.4
Hrdina, P.D.5
Bown, C.D.6
Sequeira, A.7
Kushwaha, N.8
Morris, S.J.9
Basak, A.10
Ou, X.-M.11
Albert, P.R.12
-
86
-
-
0006463359
-
Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
-
DOI 10.1126/science.274.5292.1527
-
Lesch, K.-P., Bengel, D., Heils, A., Sabol, S.Z., Greenberg, B.D., Petri, S., Benjamin, J., Müller, C.R., Hamer, D.H., and Murphy, D.L. (1996). Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274, 1527-1531. (Pubitemid 26403928)
-
(1996)
Science
, vol.274
, Issue.5292
, pp. 1527-1531
-
-
Lesch, K.-P.1
Bengel, D.2
Heils, A.3
Sabol, S.Z.4
Greenberg, B.D.5
Petri, S.6
Benjamin, J.7
Muller, C.R.8
Hamer, D.H.9
Murphy, D.L.10
-
87
-
-
79957439084
-
Polymorphism of the 5-HT transporter and response to anti depressants: Randomised controlled trial
-
Lewis, G., Mulligan, J., Wiles, N., Cowen, P., Craddock, N., Ikeda, M., Grozeva, D., Mason, V., Nutt, D., Sharp, D., et al. (2011). Polymorphism of the 5-HT transporter and response to anti depressants: randomised controlled trial. Br. J. Psychiatry 198, 464-471.
-
(2011)
Br. J. Psychiatry
, vol.198
, pp. 464-471
-
-
Lewis, G.1
Mulligan, J.2
Wiles, N.3
Cowen, P.4
Craddock, N.5
Ikeda, M.6
Grozeva, D.7
Mason, V.8
Nutt, D.9
Sharp, D.10
-
88
-
-
0037343950
-
2C receptors in serotonin transporter knockout mice
-
DOI 10.1046/j.1471-4159.2003.01607.x
-
Li, Q., Wichems, C.H., Ma, L., Van de Kar, L.D., Garcia, F., and Murphy, D.L. (2003). Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice. J. Neurochem. 84, 1256-1265. (Pubitemid 36343592)
-
(2003)
Journal of Neurochemistry
, vol.84
, Issue.6
, pp. 1256-1265
-
-
Li, Q.1
Wichems, C.H.2
Ma, L.3
Van De Kar, L.D.4
Garcia, F.5
Murphy, D.L.6
-
89
-
-
70349575487
-
Support for the involvement of the KCNK2 gene in major depressive disorder and response to antidepressant treatment
-
Liou, Y.-J., Chen, T.-J., Tsai, S.-J., Yu, Y.W.-Y., Cheng, C.-Y., and Hong, C.-J. (2009). Support for the involvement of the KCNK2 gene in major depressive disorder and response to antidepressant treatment. Pharmacogenet. Genomics 19, 735-741.
-
(2009)
Pharmacogenet. Genomics
, vol.19
, pp. 735-741
-
-
Liou, Y.-J.1
Chen, T.-J.2
Tsai, S.-J.3
Yu, Y.W.-Y.4
Cheng, C.-Y.5
Hong, C.-J.6
-
90
-
-
0242456044
-
Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice
-
DOI 10.1016/S0006-3223(03)00696-6
-
Lira, A., Zhou, M., Castanon, N., Ansorge, M.S., Gordon, J.A., Francis, J.H., Bradley-Moore, M., Lira, J., Underwood, M.D., Arango, V., et al. (2003). Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice. Biol. Psychiatry 54, 960-971. (Pubitemid 37415032)
-
(2003)
Biological Psychiatry
, vol.54
, Issue.10
, pp. 960-971
-
-
Lira, A.1
Zhou, M.2
Castanon, N.3
Ansorge, M.S.4
Gordon, J.A.5
Francis, J.H.6
Bradley-Moore, M.7
Lira, J.8
Underwood, M.D.9
Arango, V.10
Kung, H.F.11
Hofer, M.A.12
Hen, R.13
Gingrich, J.A.14
-
91
-
-
1642441801
-
2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia
-
DOI 10.1016/j.biopsych.2003.09.017
-
Lopez-Figueroa, A., Norton, C., Lopez-Figueroa, M., Armellini- Dodel, D., Burke, S., Akil, H., Lopez, J., and Watson, S. (2004). Serotonin 5-HT 1A, 5-HT1B, and 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia. Biol. Psychiatry 55, 225-233. (Pubitemid 38117158)
-
(2004)
Biological Psychiatry
, vol.55
, Issue.3
, pp. 225-233
-
-
Lopez-Figueroa, A.L.1
Norton, C.S.2
Lopez-Figueroa, M.O.3
Armellini-Dodel, D.4
Burke, S.5
Akil, H.6
Lopez, J.F.7
Watson, S.J.8
-
92
-
-
70450173564
-
Serotonin receptors, type 4: A new hope?
-
Lucas, G. (2009). Serotonin receptors, type 4: a new hope? Curr. Drug Targets 10, 1085-1095.
-
(2009)
Curr. Drug Targets
, vol.10
, pp. 1085-1095
-
-
Lucas, G.1
-
93
-
-
34548246547
-
4) Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action
-
DOI 10.1016/j.neuron.2007.07.041, PII S0896627307006186
-
Lucas, G., Rymar, V.V., Du, J., Mnie-Filali, O., Bisgaard, C., Manta, S., Lambas-Senas, L., Wiborg, O., Haddjeri, N., Pineyro, G., et al. (2007). Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action. Neuron 55, 712-725. (Pubitemid 47334877)
-
(2007)
Neuron
, vol.55
, Issue.5
, pp. 712-725
-
-
Lucas, G.1
Rymar, V.V.2
Du, J.3
Mnie-Filali, O.4
Bisgaard, C.5
Manta, S.6
Lambas-Senas, L.7
Wiborg, O.8
Haddjeri, N.9
Pineyro, G.10
Sadikot, A.F.11
Debonnel, G.12
-
94
-
-
0033838035
-
A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide
-
Mann, J.J., Huang, Y.-y., Underwood, M.D., Kassir, S.A., Oppenheim, S., Kelly, T.M., Dwork, A.J., and Arango, V. (2000). A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide. Arch. Gen. Psychiatry 57, 729-738. (Pubitemid 30650106)
-
(2000)
Archives of General Psychiatry
, vol.57
, Issue.8
, pp. 729-738
-
-
Mann, J.J.1
Huang, Y.-Y.2
Underwood, M.D.3
Kassir, S.A.4
Oppenheim, S.5
Kelly, T.M.6
Dwork, A.J.7
Arango, V.8
-
95
-
-
10344221595
-
Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression
-
DOI 10.1016/j.jneumeth.2004.05.017, PII S0165027004002948
-
Mathews, T.A., Fedele, D.E., Coppelli, F.M., Avila, A.M., Murphy, D.L., and Andrews, A.M. (2004). Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression. J. Neurosci. Methods 140, 169-181. (Pubitemid 39625865)
-
(2004)
Journal of Neuroscience Methods
, vol.140
, pp. 169-181
-
-
Mathews, T.A.1
Fedele, D.E.2
Coppelli, F.M.3
Avila, A.M.4
Murphy, D.L.5
Andrews, A.M.6
-
96
-
-
0034887953
-
1B receptor mutant mice
-
Mayorga, A.J., Dalvi, A., Page, M.E., Zimov-Levinson, S., Hen, R., and Lucki, I. (2001). Antidepressant-like behavioral effects in 5-hydroxytryptamine 1A and 5-hydroxytryptamine 1B receptor mutant mice. J. Pharmacol. Exp. Ther. 298, 1101-1107. (Pubitemid 32761926)
-
(2001)
Journal of Pharmacology and Experimental Therapeutics
, vol.298
, Issue.3
, pp. 1101-1107
-
-
Mayorga, A.J.1
Dalvi, A.2
Page, M.E.3
Zimov-Levinson, S.4
Hen, R.5
Lucki, I.6
-
97
-
-
77951710955
-
Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: A new concept in the antidepressant drug design
-
Mazella, J., Petrault, O., Lucas, G., Deval, E., Beraud-Dufour, S., Gandin, C., El-Yacoubi, M., Widmann, C., Guyon, A., Chevet, E., et al. (2010). Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design. PLoS Biol. 8, e1000355.
-
(2010)
PLoS Biol.
, vol.8
-
-
Mazella, J.1
Petrault, O.2
Lucas, G.3
Deval, E.4
Beraud-Dufour, S.5
Gandin, C.6
El-Yacoubi, M.7
Widmann, C.8
Guyon, A.9
Chevet, E.10
-
98
-
-
0035977711
-
Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery
-
DOI 10.1016/S0169-328X(00)00263-1, PII S0169328X00002631
-
Medhurst, A.D., Rennie, G., Chapman, C.G., Meadows, H., Duckworth, M.D., Kelsell, R.E., Gloger, I.I., and Pangalos, M.N. (2001). Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery. Brain Res. Mol. Brain Res. 86, 101-114. (Pubitemid 32124764)
-
(2001)
Molecular Brain Research
, vol.86
, Issue.1-2
, pp. 101-114
-
-
Medhurst, A.D.1
Rennie, G.2
Chapman, C.G.3
Meadows, H.4
Duckworth, M.D.5
Kelsell, R.E.6
Gloger, I.I.7
Pangalos, M.N.8
-
99
-
-
33845342923
-
Effects of repeated maternal separation on anxiety- and depression-related phenotypes in different mouse strains
-
DOI 10.1016/j.neubiorev.2006.05.003, PII S0149763406000431, Neurogenetics and Behavior
-
Millstein, R. and Holmes, A. (2007). Effects of repeated maternal separation on anxiety- and depression-related phenotypes in different mouse strains. Neurosci. Biobehav. Rev. 31, 3-17. (Pubitemid 44880075)
-
(2007)
Neuroscience and Biobehavioral Reviews
, vol.31
, Issue.1
, pp. 3-17
-
-
Millstein, R.A.1
Holmes, A.2
-
100
-
-
17144466384
-
Exaggerated effect of fluvoxamine in heterozygote serotonin transporter knockout mice
-
DOI 10.1046/j.1471-4159.2003.01836.x
-
Montañez, S., Owens, W.A., Gould, G.G., Murphy, D.L., and Daws, L.C. (2003). Exaggerated effect of fluvoxamine in heterozygote serotonin transporter knockout mice. J. Neurochem. 86, 210-219. (Pubitemid 36753861)
-
(2003)
Journal of Neurochemistry
, vol.86
, Issue.1
, pp. 210-219
-
-
Montanez, S.1
Owens, W.A.2
Gould, G.G.3
Murphy, D.L.4
Daws, L.C.5
-
101
-
-
77950626655
-
Investigation of CNR1 and FAAH endocannabinoid gene polymorphisms in bipolar disorder and major depression
-
Monteleone, P., Bifulco, M., Maina, G., Tortorella, A., Gazzerro, P., Proto, M.C., Di Filippo, C., Monteleone, F., Canestrelli, B., Buonerba, G., et al. (2010). Investigation of CNR1 and FAAH endocannabinoid gene polymorphisms in bipolar disorder and major depression. Pharmacol. Res. 61, 400-404.
-
(2010)
Pharmacol. Res.
, vol.61
, pp. 400-404
-
-
Monteleone, P.1
Bifulco, M.2
Maina, G.3
Tortorella, A.4
Gazzerro, P.5
Proto, M.C.6
Di Filippo, C.7
Monteleone, F.8
Canestrelli, B.9
Buonerba, G.10
-
102
-
-
2342629856
-
Serotonin transporter: Gene, genetic disorders, and pharmacogenetics
-
DOI 10.1124/mi.4.2.8
-
Murphy, D.L., Lerner, A., Rudnick, G., and Lesch, K.-P. (2004). Serotonin transporter: gene, genetic disorders, and pharmacogenetics. Mol. Interv. 4, 109-123. (Pubitemid 38584973)
-
(2004)
Molecular Interventions
, vol.4
, Issue.2
, pp. 109-123
-
-
Murphy, D.L.1
Lerner, A.2
Rudnick, G.3
Lesch, K.-P.4
-
103
-
-
53649090041
-
How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems
-
Murphy, D., Fox, M., Timpano, K., Moya, P., Ren-Patterson, R., Andrews, A., Holmes, A., Lesch, K., and Wendland, J. (2008). How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. Neuropharmacology 55, 932-960.
-
(2008)
Neuropharmacology
, vol.55
, pp. 932-960
-
-
Murphy, D.1
Fox, M.2
Timpano, K.3
Moya, P.4
Ren-Patterson, R.5
Andrews, A.6
Holmes, A.7
Lesch, K.8
Wendland, J.9
-
104
-
-
79953688210
-
Human serotonin transporter gene (SLC6A4) variants: Their contributions to understanding pharmacogenomic and other functional G×G and G×E differences in health and disease
-
Murphy, D.L. and Moya, P.R. (2011). Human serotonin transporter gene (SLC6A4) variants: their contributions to understanding pharmacogenomic and other functional G×G and G×E differences in health and disease. Curr. Opin. Pharmacol. 11, 3-10.
-
(2011)
Curr. Opin. Pharmacol.
, vol.11
, pp. 3-10
-
-
Murphy, D.L.1
Moya, P.R.2
-
105
-
-
44849104847
-
Serotonin receptors
-
DOI 10.1021/cr078224o
-
Nichols, D.E. and Nichols, C.D. (2008). Serotonin receptors. Chem. Rev. 108, 1614-1641. (Pubitemid 351796401)
-
(2008)
Chemical Reviews
, vol.108
, Issue.5
, pp. 1614-1641
-
-
Nichols, D.E.1
Nichols, C.D.2
-
106
-
-
0036430342
-
Association between serotonin 4 receptor gene polymorphisms and bipolar disorder in Japanese case-control samples and the NIMH Genetics Initiative Bipolar Pedigrees
-
DOI 10.1038/sj.mp.4001133
-
Ohtsuki, T., Ishiguro, H., Detera-Wadleigh, S.D., Toyota, T., Shimizu, H., Yamada, K., Yoshitsugu, K., Hattori, E., Yoshikawa, T., and Arinami, T. (2002). Association between serotonin 4 receptor gene polymorphisms and bipolar disorder in japanese case-control samples and the NIMH genetics initiative bipolar pedigrees. Mol. Psychiatry 7, 954-961. (Pubitemid 35333050)
-
(2002)
Molecular Psychiatry
, vol.7
, Issue.9
, pp. 954-961
-
-
Ohtsuki, T.1
Ishiguro, H.2
Detera-Wadleigh, S.D.3
Toyota, T.4
Shimizu, H.5
Yamada, K.6
Yoshitsugu, K.7
Hattori, E.8
Yoshikawa, T.9
Arinami, T.10
-
107
-
-
75949118126
-
Prospects for epigenetic research within cohort studies of psychological disorder: A pilot investigation of a peripheral cell marker of epigenetic risk for depression
-
Olsson, C.A., Foley, D.L., Parkinson-Bates, M., Byrnes, G., McKenzie, M., Patton, G.C., Morley, R., Anney, R.J., Craig, J.M., and Saffery, R. (2010). Prospects for epigenetic research within cohort studies of psychological disorder: a pilot investigation of a peripheral cell marker of epigenetic risk for depression. Biol. Psychol. 83, 159-165.
-
(2010)
Biol. Psychol.
, vol.83
, pp. 159-165
-
-
Olsson, C.A.1
Foley, D.L.2
Parkinson-Bates, M.3
Byrnes, G.4
McKenzie, M.5
Patton, G.C.6
Morley, R.7
Anney, R.J.8
Craig, J.M.9
Saffery, R.10
-
108
-
-
84856351442
-
Modeling depression in animal models
-
Overstreet, D.H. (2012). Modeling depression in animal models. Methods Mol. Biol. 829, 125-144.
-
(2012)
Methods Mol. Biol.
, vol.829
, pp. 125-144
-
-
Overstreet, D.H.1
-
109
-
-
0032169414
-
Increased anxiety of mice lacking the serotonin 1A receptor
-
Parks, C.L., Robinson, P.S., Sibille, E., Shenk, T., and Toth, M. (1998). Increased anxiety of mice lacking the serotonin 1A receptor. Proc. Nat. Acad. Sci. USA 95, 10734-10739.
-
(1998)
Proc. Nat. Acad. Sci. USA
, vol.95
, pp. 10734-10739
-
-
Parks, C.L.1
Robinson, P.S.2
Sibille, E.3
Shenk, T.4
Toth, M.5
-
110
-
-
30044435499
-
Lower serotonin transporter binding potential in the human brain during major depressive episodes
-
DOI 10.1176/appi.ajp.163.1.52
-
Parsey, R.V., Hastings, R.S., Oquendo, M.A., Huang, Y.-Y., Simpson, N., Arcement, J., Huang, Y., Ogden, R.T., Van Heertum, R.L., Arango, V., et al. (2006a). Lower serotonin transporter binding potential in the human brain during major depressive episodes. Am. J. Psychiatry 163, 52-58. (Pubitemid 43050103)
-
(2006)
American Journal of Psychiatry
, vol.163
, Issue.1
, pp. 52-58
-
-
Parsey, R.V.1
Hastings, R.S.2
Oquendo, M.A.3
Huang, Y.-Y.4
Simpson, N.5
Arcement, J.6
Huang, Y.7
Ogden, R.T.8
Van Heertum, R.L.9
Arango, V.10
Mann, J.J.11
-
111
-
-
33746322712
-
1A receptor binding potential during a major depressive episode predicts poor treatment response: Preliminary data from a naturalistic study
-
DOI 10.1038/sj.npp.1300992, PII 1300992
-
Parsey, R.V., Olvet, D., Oquendo, M., Huang, Y., Ogden, R., and Mann, J. (2006b). Higher 5-HT 1A receptor binding potential during a major depressive episode predicts poor treatment response: preliminary data from a naturalistic study. Neuropsychopharmacology 31, 1745-1749. (Pubitemid 44106705)
-
(2006)
Neuropsychopharmacology
, vol.31
, Issue.8
, pp. 1745-1749
-
-
Parsey, R.V.1
Olvet, D.M.2
Oquendo, M.A.3
Huang, Y.-Y.4
Ogden, R.T.5
Mann, J.J.6
-
112
-
-
77954216048
-
Higher serotonin 1A binding in a second major depression cohort: Modeling and reference region considerations
-
Parsey, R., Ogden, R., Miller, J., Tin, A., Hesselgrave, N., Goldstein, E., Mikhno, A., Milak, M., Zanderigo, F., Sullivan, G., et al. (2010). Higher serotonin 1A binding in a second major depression cohort: modeling and reference region considerations. Biol. Psychiatry 68, 170-178.
-
(2010)
Biol. Psychiatry
, vol.68
, pp. 170-178
-
-
Parsey, R.1
Ogden, R.2
Miller, J.3
Tin, A.4
Hesselgrave, N.5
Goldstein, E.6
Mikhno, A.7
Milak, M.8
Zanderigo, F.9
Sullivan, G.10
-
113
-
-
0035371189
-
+ channels
-
DOI 10.1016/S0166-2236(00)01810-5, PII S0166223600018105
-
Patel, A.J. and Honore, E. (2001). Properties and modulation of mammalian 2P domain K+ channels. Trends Neurosci. 24, 339-346. (Pubitemid 32455435)
-
(2001)
Trends in Neurosciences
, vol.24
, Issue.6
, pp. 339-346
-
-
Patel, A.J.1
Honore, E.2
-
114
-
-
0022346190
-
Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors
-
DOI 10.1016/0006-8993(85)90856-X
-
Pazos, A. and Palacios, J.M. (1985). Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors. Brain Res. 346, 205-230. (Pubitemid 16241111)
-
(1985)
Brain Research
, vol.346
, Issue.2
, pp. 205-230
-
-
Pazos, A.1
Palacios, J.M.2
-
115
-
-
50249189084
-
Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: Association of TREK1 and treatment resistance in the STAR(*)D study
-
Perlis, R.H., Moorjani, P., Fagerness, J., Purcell, S., Trivedi, M.H., Fava, M., Rush, A.J., and Smoller, J.W. (2008). Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study. Neuropsychopharmacology 33, 2810-2819.
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 2810-2819
-
-
Perlis, R.H.1
Moorjani, P.2
Fagerness, J.3
Purcell, S.4
Trivedi, M.H.5
Fava, M.6
Rush, A.J.7
Smoller, J.W.8
-
116
-
-
0345540627
-
Autoregulation of serotonin neurons: Role in antidepressant drug action
-
Pineyro, G. and Blier, P. (1999). Autoregulation of serotonin neurons: role in antidepressant drug action. Pharmacol. Rev. 51, 533-591. (Pubitemid 29420214)
-
(1999)
Pharmacological Reviews
, vol.51
, Issue.3
, pp. 533-591
-
-
Pineyro, G.1
Blier, P.2
-
117
-
-
43649087841
-
Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: Evidence from sleep, stress, and behavior
-
Popa, D., Léna, C., Alexandre, C., and Adrien, J. (2008). Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior. J. Neurosci. 28, 3546-3554.
-
(2008)
J. Neurosci.
, vol.28
, pp. 3546-3554
-
-
Popa, D.1
Léna, C.2
Alexandre, C.3
Adrien, J.4
-
118
-
-
0027405191
-
Antidepressant- and cocaine-sensitive human serotonin transporter: Molecular cloning, expression, and chromosomal localization
-
Ramamoorthy, S., Bauman, A.L., Moore, K.R., Han, H., Yang-Feng, T., Chang, A.S., Ganapathy, V., and Blakely, R.D. (1993). Anti depressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization. Proc. Nat. Acad. Sci. USA 90, 2542-2546. (Pubitemid 23078664)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.6
, pp. 2542-2546
-
-
Ramamoorthy, S.1
Bauman, A.L.2
Moore, K.R.3
Han, H.4
Yang-Feng, T.5
Chang, A.S.6
Ganapathy, V.7
Blakely, R.D.8
-
119
-
-
0032564431
-
Serotonin receptor 1A knockout: An animal model of anxiety-related disorder
-
DOI 10.1073/pnas.95.24.14476
-
Ramboz, S., Oosting, R., Amara, D.A., Kung, H.F., Blier, P., Mendelsohn, M., Mann, J.J., Brunner, D., and Hen, R. (1998). Serotonin receptor 1A knockout: an animal model of anxietyrelated disorder. Proc. Nat. Acad. Sci. USA 95, 14476-14481. (Pubitemid 28549392)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.24
, pp. 14476-14481
-
-
Ramboz, S.1
Oosting, R.2
Amara, D.A.3
Kung, H.F.4
Blier, P.5
Mendelsohn, M.6
Mann, J.J.7
Brunner, D.8
Hen, R.9
-
120
-
-
0028916616
-
5-hydroxytryptamine (5-HT)4 receptors in post mortem human brain tissue: Distribution, pharmacology and effects of neurodegenerative diseases
-
Reynolds, G.P., Mason, S.L., Meldrum, A., De Keczer, S., Parnes, H., Eglen, R.M., and Wong, E.H. (1995). 5-hydroxytryptamine (5-HT)4 receptors in post mortem human brain tissue: distribution, pharmacology and effects of neurodegenerative diseases. Br. J. Pharmacol. 114, 993-998.
-
(1995)
Br. J. Pharmacol.
, vol.114
, pp. 993-998
-
-
Reynolds, G.P.1
Mason, S.L.2
Meldrum, A.3
De Keczer, S.4
Parnes, H.5
Eglen, R.M.6
Wong, E.H.7
-
121
-
-
73549116494
-
5-HT 1A autoreceptor levels determine vulnerability to stress and response to antidepressants
-
Richardson-Jones, J., Craige, C., Guiard, B., Stephen, A., Metzger, K., Kung, H., Gardier, A., Dranovsky, A., David, D., Beck, S., et al. (2010). 5-HT 1A autoreceptor levels determine vulnerability to stress and response to antidepressants. Neuron 65, 40-52.
-
(2010)
Neuron
, vol.65
, pp. 40-52
-
-
Richardson-Jones, J.1
Craige, C.2
Guiard, B.3
Stephen, A.4
Metzger, K.5
Kung, H.6
Gardier, A.7
Dranovsky, A.8
David, D.9
Beck, S.10
-
122
-
-
79955751906
-
Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety
-
Richardson-Jones, J.W., Craige, C.P., Nguyen, T.H., Kung, H.F., Gardier, A.M., Dranovsky, A., David, D.J., Guiard, B.P., Beck, S.G., Hen, R., et al. (2011). Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety. J. Neurosci. 31, 6008-6018.
-
(2011)
J. Neurosci.
, vol.31
, pp. 6008-6018
-
-
Richardson-Jones, J.W.1
Craige, C.P.2
Nguyen, T.H.3
Kung, H.F.4
Gardier, A.M.5
Dranovsky, A.6
David, D.J.7
Guiard, B.P.8
Beck, S.G.9
Hen, R.10
-
123
-
-
0037169256
-
1A receptors
-
DOI 10.1016/S0014-2999(01)01607-7, PII S0014299901016077
-
Richer, M., Hen, R., and Blier, P. (2002). Modification of serotonin neuron properties in mice lacking 5-HT 1A receptors. Eur. J. Pharmacol. 435, 195-203. (Pubitemid 34131700)
-
(2002)
European Journal of Pharmacology
, vol.435
, Issue.2-3
, pp. 195-203
-
-
Richer, M.1
Hen, R.2
Blier, P.3
-
124
-
-
0021360636
-
Elevation of substance P-like peptides in the CSF of psychiatric patients
-
Rimon, R., Le Greves, P., Nyberg, F., Heikkila, L., Salmela, L., and
-
(1984)
Biological Psychiatry
, vol.19
, Issue.4
, pp. 509-516
-
-
Rimon, R.1
Le Greves, P.2
Nyberg, F.3
-
125
-
-
0033525562
-
Adaptive changes of serotonin 5-HT(2A) receptors in mice lacking the serotonin transporter
-
DOI 10.1016/S0304-3940(99)00049-X, PII S030439409900049X
-
Rioux, A., Fabre, V., Peter Lesch, K., Moessner, R., Murphy, D.L., Lanfumey, L., Hamon, M., and Martres, M.-P. (1999). Adaptive changes of serotonin 5-HT2A receptors in mice lacking the serotonin transporter. Neurosci. Lett. 262, 113-116. (Pubitemid 29130301)
-
(1999)
Neuroscience Letters
, vol.262
, Issue.2
, pp. 113-116
-
-
Rioux, A.1
Fabre, V.2
Peter Lesch, K.3
Moessner, R.4
Murphy, D.L.5
Lanfumey, L.6
Hamon, M.7
Martres, M.-P.8
-
126
-
-
0019820334
-
Serotonin autoreceptors on dorsal raphe neurons: Structure-activity relationships of tryptamine analogs
-
Rogawaski, M. and Aghajanian, G. (1981). Serotonin autoreceptors on dorsal raphe neurons: structure-activity relationships of tryptamine analogs. J. Neurosci. 1, 1148-1154. (Pubitemid 12218107)
-
(1981)
Journal of Neuroscience
, vol.1
, Issue.10
, pp. 1148-1154
-
-
Rogawski, M.A.1
Aghajanian, G.K.2
-
127
-
-
2342527059
-
3 and cAmP in brains from depressed violent suicide victims
-
DOI 10.1159/000077365
-
Rosel, P., Arranz, B., Urretavizcaya, M., Oros, M., San, L., and Navarro, M.A. (2004). Altered 5-HT2A and 5-HT4 postsynaptic receptors and their intracellular signalling systems IP3 and cAMP in brains from depressed violent suicide victims. Neuropsychobiology 49, 189-195. (Pubitemid 38594570)
-
(2004)
Neuropsychobiology
, vol.49
, Issue.4
, pp. 189-195
-
-
Rosel, P.1
Arranz, B.2
Urretavizcaya, M.3
Oros, M.4
San, L.5
Navarro, M.A.6
-
128
-
-
0027364736
-
From synapse to vesicle: The reuptake and storage of biogenic amine neurotransmitters
-
DOI 10.1016/0005-2728(93)90109-S
-
Rudnick, G. and Clark, J. (1993). From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters. Biochim. Biophys. Acta 1144, 249-263. (Pubitemid 23290252)
-
(1993)
Biochimica et Biophysica Acta - Bioenergetics
, vol.1144
, Issue.3
, pp. 249-263
-
-
Rudnick, G.1
Clark, J.2
-
129
-
-
0035218323
-
1) receptor in assays for antidepressant and anxiolytic drugs
-
Rupniak, N., Carlson, E., Webb, J., Harrison, T., Porsolt, R., Roux, S., de Felipe, C., Hunt, S., Oates, B., and Wheeldon, A. (2001). Comparison of the phenotype of NK1R-/- mice with pharmacological blockade of the substance P (NK1) receptor in assays for antidepressant and anxiolytic drugs. Behav. Pharmacol. 12, 497-508. (Pubitemid 33152274)
-
(2001)
Behavioural Pharmacology
, vol.12
, Issue.6-7
, pp. 497-508
-
-
Rupniak, N.M.J.1
Carlson, E.J.2
Webb, J.K.3
Harrison, T.4
Porsolt, R.D.5
Roux, S.6
De Felipe, C.7
Hunt, S.P.8
Oates, B.9
Wheeldon, A.10
-
130
-
-
0035852719
-
Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function
-
DOI 10.1073/pnas.041596398
-
Santarelli, L., Gobbi, G., Debs, P.C., Sibille, E.L., Blier, P., Hen, R., and Heath, M.J.S. (2001). Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxietyrelated behaviors and increases serotonergic function. Proc. Nat. Acad. Sci. USA 98, 1912-1917. (Pubitemid 32165597)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.4
, pp. 1912-1917
-
-
Santarelli, L.1
Gobbi, G.2
Debs, P.C.3
Sibille, E.L.4
Blier, P.5
Hen, R.6
Heath, M.J.S.7
-
131
-
-
0042528720
-
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
-
DOI 10.1126/science.1083328
-
Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003). Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301, 805-809. (Pubitemid 36962615)
-
(2003)
Science
, vol.301
, Issue.5634
, pp. 805-809
-
-
Santarelli, L.1
Saxe, M.2
Gross, C.3
Surget, A.4
Battaglia, F.5
Dulawa, S.6
Weisstaub, N.7
Lee, J.8
Duman, R.9
Arancio, O.10
Belzung, C.11
Hen, R.12
-
132
-
-
84857397957
-
Etiology of depression: Genetic and enviromental factors
-
Saveanu, R.V. and Nemeroff, C.B. (2012). Etiology of depression: genetic and enviromental factors. Psychiatr. Clin. North Am. 35, 51-71.
-
(2012)
Psychiatr. Clin. North Am.
, vol.35
, pp. 51-71
-
-
Saveanu, R.V.1
Nemeroff, C.B.2
-
133
-
-
0024997056
-
Application of brain microdialysis to study the pharmacology of the 5-HT(1A) autoreceptor
-
DOI 10.1016/0165-0270(90)90045-H
-
Sharp, T. and Hjorth, S. (1990). Application of brain microdialysis to study the pharmacology of the 5-HT 1A autoreceptor. J. Neurosci. Methods 34, 83-90. (Pubitemid 20301325)
-
(1990)
Journal of Neuroscience Methods
, vol.34
, Issue.1-3
, pp. 83-90
-
-
Sharp, T.1
Hjorth, S.2
-
134
-
-
0030580383
-
Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat
-
DOI 10.1016/S0006-8993(96)00812-8, PII S0006899396008128
-
Shirayama, Y., Mitsushio, H., Takashima, M., Ichikawa, H., and Takahashi, K. (1996). Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat. Brain Res. 739, 70-78. (Pubitemid 26387364)
-
(1996)
Brain Research
, vol.739
, Issue.1-2
, pp. 70-78
-
-
Shirayama, Y.1
Mitsushio, H.2
Takashima, M.3
Ichikawa, H.4
Takahashi, K.5
-
135
-
-
33846837326
-
Evaluation of reward processes in an animal model of depression
-
DOI 10.1007/s00213-006-0630-x
-
Slattery, D.A., Markou, A., and Cryan, J.F. (2007). Evaluation of reward processes in an animal model of depression. Psychopharmacol. (Berl.) 190, 555-568. (Pubitemid 46204472)
-
(2007)
Psychopharmacology
, vol.190
, Issue.4
, pp. 555-568
-
-
Slattery, D.A.1
Markou, A.2
Cryan, J.F.3
-
136
-
-
0025612473
-
Direct immuno-histochemical evidence of the existence of 5-HT 1A autoreceptors on serotoninergic neurons in the midbrain raphe nuclei
-
Sotelo, C., Cholley, B., El Mestikawy, S., Gozlan, H., and Hamon, M. (1990). Direct immuno-histochemical evidence of the existence of 5-HT 1A autoreceptors on serotoninergic neurons in the midbrain raphe nuclei. Eur. J. Neurosci. 2, 1144-1154.
-
(1990)
Eur. J. Neurosci.
, vol.2
, pp. 1144-1154
-
-
Sotelo, C.1
Cholley, B.2
El Mestikawy, S.3
Gozlan, H.4
Hamon, M.5
-
137
-
-
0031080939
-
Serotonin receptors in suicide victims with major depression
-
DOI 10.1016/S0893-133X(96)00170-4, PII S0893133X96001704
-
Stockmeier, C., Dilley, G., Shapiro, L., Overholser, J., Thompson, P., and Meltzer, H. (1997). Serotonin receptors in suicide victims with major depression. Neuropsychopharmacology 16, 162-173. (Pubitemid 27086431)
-
(1997)
Neuropsychopharmacology
, vol.16
, Issue.2
, pp. 162-173
-
-
Stockmeier, C.A.1
Dilley, G.E.2
Shapiro, L.A.3
Overholser, J.C.4
Thompson, P.A.5
Meltzer, H.Y.6
-
138
-
-
0037007968
-
Neurokinin-1 receptors are decreased in major depressive disorder
-
Stockmeier, C., Shi, X., Konick, L., Overholser, J., Jurjus, G., Meltzer, H., Friedman, L., Blier, P., and Rajkowska, G. (2002). Neurokinin-1 receptors are decreased in major depressive disorder. Neuroreport 13, 1223-1227. (Pubitemid 34722058)
-
(2002)
NeuroReport
, vol.13
, Issue.9
, pp. 1223-1227
-
-
Stockmeier, C.A.1
Shi, X.2
Konick, L.3
Overholser, J.C.4
Jurjus, G.5
Meltzer, H.Y.6
Friedman, L.7
Blier, P.8
Rajkowska, G.9
-
139
-
-
67349255009
-
Antagonist but not agonist labeling of serotonin-1A receptors is decreased in major depressive disorder
-
Stockmeier, C., Howley, E., Shi, X., Sobanska, A., Clarke, G., Friedman, L., and Rajkowska, G. (2009). Antagonist but not agonist labeling of serotonin-1A receptors is decreased in major depressive disorder. J. Psychiatr. Res. 43, 887-894.
-
(2009)
J. Psychiatr. Res.
, vol.43
, pp. 887-894
-
-
Stockmeier, C.1
Howley, E.2
Shi, X.3
Sobanska, A.4
Clarke, G.5
Friedman, L.6
Rajkowska, G.7
-
140
-
-
0035478067
-
CNS distribution of members of the two-pore-domain (KCNK) potassium channel family
-
Talley, E.M., Solorzano, G., Lei, Q., Kim, D., and Bayliss, D.A. (2001). CNS distribution of members of the two-pore-domain (KCNK) potassium channel family. J. Neurosci. 21, 7491-7505. (Pubitemid 32904948)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.19
, pp. 7491-7505
-
-
Talley, E.M.1
Solorzano, G.2
Lei, Q.3
Kim, D.4
Bayliss, D.A.5
-
141
-
-
0035157987
-
Mouse molecular genetic technologies: Promise for psychiatric research
-
Tecott, L.H. and Wehner, J.M. (2001). Mouse molecular genetic technologies: promise for psychiatric research. Arch. Gen. Psychiatry 58, 995-1004. (Pubitemid 33051825)
-
(2001)
Archives of General Psychiatry
, vol.58
, Issue.11
, pp. 995-1004
-
-
Tecott, L.H.1
Wehner, J.M.2
-
142
-
-
34447580198
-
The fatty acid amide hydrolase C385A (P129T) missense variant in cannabis users: Studies of drug use and dependence in caucasians
-
DOI 10.1002/ajmg.b.30491
-
Tyndale, R., Payne, J., Gerber, A., and Sipe, J. (2007). The fatty acid amide hydrolase c385a (P129T) missense variant in cannabis users: studies of drug use and dependence in caucasians. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B, 660-666. (Pubitemid 47077151)
-
(2007)
American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics
, vol.144
, Issue.5
, pp. 660-666
-
-
Tyndale, R.F.1
Payne, J.I.2
Gerber, A.L.3
Sipe, J.C.4
-
143
-
-
79958039842
-
Genes, environment, and individual differences in responding to treatment for depression
-
Uher, R. (2011). Genes, environment, and individual differences in responding to treatment for depression. Harv. Rev. Psychiatry 19, 109-124.
-
(2011)
Harv. Rev. Psychiatry
, vol.19
, pp. 109-124
-
-
Uher, R.1
-
144
-
-
0043127401
-
Substance P acts through local circuits within the rat dorsal raphe nucleus to alter serotonergic neuronal activity
-
Valentino, R.J., Bey, V., Pernar, L., and Commons, K.G. (2003). Substance P acts through local circuits within the rat dorsal raphe nucleus to alter serotonergic neuronal activity. J. Neurosci. 23, 7155-7159. (Pubitemid 36975879)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.18
, pp. 7155-7159
-
-
Valentino, R.J.1
Bey, V.2
Pernar, L.3
Commons, K.G.4
-
145
-
-
0030828015
-
4 receptor cDNA
-
Van den Wyngaert, I., Gommeren, W., Verhasselt, P., Jurzak, M., Leysen, J., Luyten, W., and Bender, E. (1997). Cloning and expression of a human serotonin 5-HT4 receptor cDNA. J. Neurochem. 69, 1810-1819. (Pubitemid 27452725)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.5
, pp. 1810-1819
-
-
Van Den Wyngaert, I.1
Gommeren, W.2
Verhasselt, P.3
Jurzak, M.4
Leysen, J.5
Luyten, W.6
Bender, E.7
-
146
-
-
33846448741
-
Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice
-
DOI 10.1523/JNEUROSCI.4595-06.2007
-
Wellman, C.L., Izquierdo, A., Garrett, J.E., Martin, K.P., Carroll, J., Millstein, R., Lesch, K.-P., Murphy, D.L., and Holmes, A. (2007). Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice. J. Neurosci. 27, 684-691. (Pubitemid 46143772)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.3
, pp. 684-691
-
-
Wellman, C.L.1
Izquierdo, A.2
Garrett, J.E.3
Martin, K.P.4
Carroll, J.5
Millstein, R.6
Lesch, K.-P.7
Murphy, D.L.8
Holmes, A.9
-
147
-
-
0021348560
-
The validity of animal models of depression
-
Willner, P. (1984). The validity of animal models of depression. Psychopharmacol. (Berl.) 83, 1-16. (Pubitemid 14141479)
-
(1984)
Psychopharmacology
, vol.83
, Issue.1
, pp. 1-16
-
-
Willner, P.1
-
148
-
-
23844500078
-
Chronic mild stress (CMS) revisited: Consistency and behavioural- neurobiological concordance in the effects of CMS
-
DOI 10.1159/000087097
-
Willner, P. (2005). Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS. Neuropsychobiology 52, 90-110. (Pubitemid 41160326)
-
(2005)
Neuropsychobiology
, vol.52
, Issue.2
, pp. 90-110
-
-
Willner, P.1
-
149
-
-
0023636527
-
Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant
-
Willner, P., Towell, A., Sampson, D., Sophokleous, S., and Muscat, R. (1987). Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant. Psychopharmacol. (Berl.) 93, 358-364. (Pubitemid 17160661)
-
(1987)
Psychopharmacology
, vol.93
, Issue.3
, pp. 358-364
-
-
Willner, P.1
Towell, A.2
Sampson, D.3
Sophokleous, S.4
Muscat, R.5
-
150
-
-
77953184026
-
Association of MAOA, 5-HTT, and NET promoter polymorphisms with gene expression and protein activity in human placentas
-
Zhang, H., Smith, G.N., Liu, X., and Holden, J.J.A. (2010). Association of MAOA, 5-HTT, and NET promoter polymorphisms with gene expression and protein activity in human placentas. Physiol. Genomics 42, 85-92.
-
(2010)
Physiol. Genomics
, vol.42
, pp. 85-92
-
-
Zhang, H.1
Smith, G.N.2
Liu, X.3
Holden, J.J.A.4
-
151
-
-
33646379343
-
Insertion mutation at the C-terminus of the serotonin transporter disrupts brain serotonin function and emotion-related behaviors in mice
-
DOI 10.1016/j.neuroscience.2006.01.049, PII S0306452206001424
-
Zhao, S., Edwards, J., Carroll, J., Wiedholz, L., Millstein, R.A., Jaing, C., Murphy, D.L., Lanthorn, T.H., and Holmes, A. (2006). Insertion mutation at the C-terminus of the serotonin transporter disrupts brain serotonin function and emotion-related behaviors in mice. Neuroscience 140, 321-334. (Pubitemid 43668455)
-
(2006)
Neuroscience
, vol.140
, Issue.1
, pp. 321-334
-
-
Zhao, S.1
Edwards, J.2
Carroll, J.3
Wiedholz, L.4
Millstein, R.A.5
Jaing, C.6
Murphy, D.L.7
Lanthorn, T.H.8
Holmes, A.9
|