Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter

Neuropharmacology

Volumn 49, Issue 6, 2005, Pages 798-810

  Kim, Dong Kyu ^a   Tolliver, Teresa J ^a   Huang, Su Jan ^a   Martin, Bradley J ^a   Andrews, Anne M ^b,c   Wichems, Christine ^d   Holmes, Andrew ^e   Lesch, Klaus Peter ^f   Murphy, Dennis L ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

^d PFIZER INC   (United States)

^e NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^f UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Gender; Homeostasis; Knockout mouse; Serotonin transporter; Synthesis; Tryptophan hydroxylase

Indexed keywords

CARBOXYLYASE; CATECHOLAMINE; DOPAMINE; ISOENZYME; MESSENGER RNA; NORADRENALIN; SEROTONIN; SEROTONIN TRANSPORTER; TRYPTOPHAN; TRYPTOPHAN HYDROXYLASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN STEM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; FRONTAL CORTEX; GENDER; HIPPOCAMPUS; HOMEOSTASIS; HYPOTHALAMUS; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SYNTHESIS; TISSUE DISTRIBUTION; TURNOVER TIME;

ANIMALS; AORTA; BLOTTING, NORTHERN; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOPAMINE; FEMALE; GENE EXPRESSION REGULATION; HYDROXYINDOLEACETIC ACID; KIDNEY; LEVODOPA; LIVER; LUNG; MALE; METHYLDOPA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; MYOCARDIUM; NONLINEAR DYNAMICS; NORETHANDROLONE; PANCREAS; RNA, MESSENGER; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEX FACTORS; SPLEEN; TIME FACTORS; TRYPTOPHAN HYDROXYLASE;

EID: 26944447116     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2005.08.010     Document Type: Article

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