-
1
-
-
0006463359
-
Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
-
DOI 10.1126/science.274.5292.1527
-
K.P. Lesch, D. Bengel, A. Heils, S.Z. Sabol, B.D. Greenberg, S. Petri, J. Benjamin, C.R. Muller, D.H. Hamer, and D.L. Murphy Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region Science 274 1996 1527 1531 First full report of the consequences of the SLC6A4 5′ region 5HTLPR indel with effects on 3H-5HT uptake, mRNA and reporter gene expression changes plus differential allele associations with neuroticism and related personality traits in >600 individuals. (Pubitemid 26403928)
-
(1996)
Science
, vol.274
, Issue.5292
, pp. 1527-1531
-
-
Lesch, K.-P.1
Bengel, D.2
Heils, A.3
Sabol, S.Z.4
Greenberg, B.D.5
Petri, S.6
Benjamin, J.7
Muller, C.R.8
Hamer, D.H.9
Murphy, D.L.10
-
2
-
-
33646072813
-
Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder
-
X.Z. Hu, R.H. Lipsky, G. Zhu, L.A. Akhtar, J. Taubman, B.D. Greenberg, K. Xu, P.D. Arnold, M.A. Richter, and J.L. Kennedy Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder Am J Hum Genet 78 2006 815 826 Discovery of a 5′ SNP modifying the SLC6A4 5HTLPR with combination alleles formed strongly associated with OCD in two large samples, plus explication of strong ethnic influences on allele distributions.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 815-826
-
-
Hu, X.Z.1
Lipsky, R.H.2
Zhu, G.3
Akhtar, L.A.4
Taubman, J.5
Greenberg, B.D.6
Xu, K.7
Arnold, P.D.8
Richter, M.A.9
Kennedy, J.L.10
-
3
-
-
0033593033
-
A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo
-
DOI 10.1073/pnas.96.26.15251
-
A. MacKenzie, and J. Quinn A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo Proc Natl Acad Sci USA 96 1999 15251 15255 First description of a functional Stin2 SLC6A4 variant now associated with multiple disorders. (Pubitemid 30019798)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.26
, pp. 15251-15255
-
-
MacKenzie, A.1
Quinn, J.2
-
4
-
-
0242637392
-
Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype
-
DOI 10.1038/sj.mp.4001365
-
N. Ozaki, D. Goldman, W.H. Kaye, K. Plotnicov, B.D. Greenberg, J. Lappalainen, G. Rudnick, and D.L. Murphy Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype Mol Psychiatry 8 2003 933 936 (Pubitemid 37421700)
-
(2003)
Molecular Psychiatry
, vol.8
, Issue.11
, pp. 933-936
-
-
Ozaki, N.1
Goldman, D.2
Kaye, W.H.3
Plotnicov, K.4
Greenberg, B.D.5
Lappalainen, J.6
Rudnick, G.7
Murphy, D.L.8
-
5
-
-
23844454012
-
Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase
-
DOI 10.1073/pnas.0501432102
-
H.C. Prasad, C.B. Zhu, J.L. McCauley, D.J. Samuvel, S. Ramamoorthy, R.C. Shelton, W.A. Hewlett, J.S. Sutcliffe, and R.D. Blakely Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase Proc Natl Acad Sci USA 102 2005 11545 11550 Detailed explication of SLC6A4 coding region variants and their regulation. (Pubitemid 41153856)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.32
, pp. 11545-11550
-
-
Prasad, H.C.1
Zhu, C.-B.2
McCauley, J.L.3
Samuvel, D.J.4
Ramamoorthy, S.5
Shelton, R.C.6
Hewlett, W.A.7
Sutcliffe, J.S.8
Blakely, R.D.9
-
6
-
-
77956677763
-
MiR-16 targets the serotonin transporter: A new facet for adaptive responses to antidepressants
-
A. Baudry, S. Mouillet-Richard, B. Schneider, J.M. Launay, and O. Kellermann miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants Science 329 2010 1537 1541 The microRNA miR-16 was found to be the first 3′UTR modulator of SLC6A4 expression with sensitivity to fluoxetine.
-
(2010)
Science
, vol.329
, pp. 1537-1541
-
-
Baudry, A.1
Mouillet-Richard, S.2
Schneider, B.3
Launay, J.M.4
Kellermann, O.5
-
7
-
-
39749154209
-
A novel, putative gain-of-function haplotype at SLC6A4 associates with obsessive-compulsive disorder
-
DOI 10.1093/hmg/ddm343
-
J.R. Wendland, P.R. Moya, M.R. Kruse, R.F. Ren-Patterson, C.L. Jensen, K.R. Timpano, and D.L. Murphy A novel, putative gain-of-function haplotype at SLC6A4 associates with obsessive-compulsive disorder Hum Mol Genet 17 2008 717 723 The largest study documenting gain-of-function SLC6A4 expression changes contributing to a haplotypic association with OCD. (Pubitemid 351292260)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.5
, pp. 717-723
-
-
Wendland, J.R.1
Moya, P.R.2
Kruse, M.R.3
Ren-Patterson, R.F.4
Jensen, C.L.5
Timpano, K.R.6
Murphy, D.L.7
-
8
-
-
0031930348
-
Cocaine, ethanol, and genotype effects on human midbrain serotonin transporter binding sites and mRNA levels
-
K.Y. Little, D.P. McLaughlin, L. Zhang, C.S. Livermore, G.W. Dalack, P.R. McFinton, Z.S. DelProposto, E. Hill, B.J. Cassin, and S.J. Watson Cocaine, ethanol, and genotype effects on human midbrain serotonin transporter binding sites and mRNA levels Am J Psychiatry 155 1998 207 213 Documentation of SLC6A4 differential allele associations in human post-mortem brain. (Pubitemid 28074282)
-
(1998)
American Journal of Psychiatry
, vol.155
, Issue.2
, pp. 207-213
-
-
Little, K.Y.1
McLaughlin, D.P.2
Zhang, L.3
Livermore, C.S.4
Dalack, G.W.5
McFinton, P.R.6
Delproposto, Z.S.7
Hill, E.8
Cassin, B.J.9
Watson, S.J.10
Cook, E.H.11
-
9
-
-
77952114460
-
Boron-doped diamond microelectrodes reveal reduced serotonin uptake rates in lymphocytes from adult rhesus monkeys carrying the short allele of the 5-HTTLPR
-
Y.S. Singh, L.E. Sawarynski, H.M. Michael, R.E. Ferrell, M.A. Murphey-Corb, G.M. Swain, B.A. Patel, and A.M. Andrews Boron-doped diamond microelectrodes reveal reduced serotonin uptake rates in lymphocytes from adult rhesus monkeys carrying the short allele of the 5-HTTLPR ACS Chem Neurosci 1 2010 49 64
-
(2010)
ACS Chem Neurosci
, vol.1
, pp. 49-64
-
-
Singh, Y.S.1
Sawarynski, L.E.2
Michael, H.M.3
Ferrell, R.E.4
Murphey-Corb, M.A.5
Swain, G.M.6
Patel, B.A.7
Andrews, A.M.8
-
10
-
-
77956203458
-
Imaging the effects of genetic polymorphisms on radioligand binding in the living human brain: A review on genetic neuroreceptor imaging of monoaminergic systems in psychiatry
-
M. Willeit, and N. Praschak-Rieder Imaging the effects of genetic polymorphisms on radioligand binding in the living human brain: a review on genetic neuroreceptor imaging of monoaminergic systems in psychiatry Neuroimage 53 2010 878 892 14C-DASB shown to be a superior PET ligand for SERT, with demonstration of binding potentials correlating highly in brain with SLC6A4 alleles.
-
(2010)
Neuroimage
, vol.53
, pp. 878-892
-
-
Willeit, M.1
Praschak-Rieder, N.2
-
11
-
-
0042343721
-
A human serotonin transporter mutation causes constitutive activation of transport activity
-
DOI 10.1124/mol.64.2.440
-
F. Kilic, D.L. Murphy, and G. Rudnick A human serotonin transporter mutation causes constitutive activation of transport activity Mol Pharmacol 64 2003 440 446 First of now several SLC6A4 coding region variants associated with disease states: SERT I425V is now 'OCD1' in OMIM. (Pubitemid 36910008)
-
(2003)
Molecular Pharmacology
, vol.64
, Issue.2
, pp. 440-446
-
-
Kilic, F.1
Murphy, D.L.2
Rudnick, G.3
-
12
-
-
71649094840
-
Combinatorial interaction between two human serotonin transporter gene variable number tandem repeats and their regulation by CTCF
-
F.R. Ali, S.A. Vasiliou, K. Haddley, U.M. Paredes, J.C. Roberts, F. Miyajima, E. Klenova, V.J. Bubb, and J.P. Quinn Combinatorial interaction between two human serotonin transporter gene variable number tandem repeats and their regulation by CTCF J Neurochem 112 2010 296 306 One of first studies exploring interactions between SLC6A4 5HTTLPR and Stin2 and their regulation.
-
(2010)
J Neurochem
, vol.112
, pp. 296-306
-
-
Ali, F.R.1
Vasiliou, S.A.2
Haddley, K.3
Paredes, U.M.4
Roberts, J.C.5
Miyajima, F.6
Klenova, E.7
Bubb, V.J.8
Quinn, J.P.9
-
13
-
-
74749096178
-
Association of a polyadenylation polymorphism in the serotonin transporter and panic disorder
-
S. Gyawali, R. Subaran, M.M. Weissman, D. Hershkowitz, M.C. McKenna, A. Talati, A.J. Fyer, P. Wickramaratne, P.B. Adams, and S.E. Hodge Association of a polyadenylation polymorphism in the serotonin transporter and panic disorder Biol Psychiatry 67 2010 331 338 A detailed study of the 3′ poly-A area.
-
(2010)
Biol Psychiatry
, vol.67
, pp. 331-338
-
-
Gyawali, S.1
Subaran, R.2
Weissman, M.M.3
Hershkowitz, D.4
McKenna, M.C.5
Talati, A.6
Fyer, A.J.7
Wickramaratne, P.8
Adams, P.B.9
Hodge, S.E.10
-
14
-
-
40949152450
-
Pharmacogenetic studies in depression: A proposal for methodologic guidelines
-
DOI 10.1038/sj.tpj.6500477, PII 6500477
-
A. Serretti, M. Kato, and J.L. Kennedy Pharmacogenetic studies in depression: a proposal for methodologic guidelines Pharmacogenomics J 8 2008 90 100 (Pubitemid 351411545)
-
(2008)
Pharmacogenomics Journal
, vol.8
, Issue.2
, pp. 90-100
-
-
Serretti, A.1
Kato, M.2
Kennedy, J.L.3
-
15
-
-
77956170298
-
Antidepressant response and the serotonin transporter gene-linked polymorphic region
-
M.J. Taylor, S. Sen, and Z. Bhagwagar Antidepressant response and the serotonin transporter gene-linked polymorphic region Biol Psychiatry 68 2010 536 543
-
(2010)
Biol Psychiatry
, vol.68
, pp. 536-543
-
-
Taylor, M.J.1
Sen, S.2
Bhagwagar, Z.3
-
16
-
-
78049499922
-
The pharmacogenetics of antidepressant-induced mania: A systematic review and meta-analysis
-
F.M. Daray, S.B. Thommi, and S.N. Ghaemi The pharmacogenetics of antidepressant-induced mania: a systematic review and meta-analysis Bipolar Disord 12 2010 702 706 A large study documenting switches to mania during early antidepressant treatment, a contributing side effect that limited SRI tolerance.
-
(2010)
Bipolar Disord
, vol.12
, pp. 702-706
-
-
Daray, F.M.1
Thommi, S.B.2
Ghaemi, S.N.3
-
17
-
-
63449100482
-
SLC6A4 variation and citalopram response
-
D.A. Mrazek, A.J. Rush, J.M. Biernacka, D.J. O'Kane, J.M. Cunningham, E.D. Wieben, D.J. Schaid, M.S. Drews, V.L. Courson, and K.A. Snyder SLC6A4 variation and citalopram response Am J Med Genet B Neuropsychiatr Genet 150B 2009 341 351
-
(2009)
Am J Med Genet B Neuropsychiatr Genet
, vol.150
, pp. 341-351
-
-
Mrazek, D.A.1
Rush, A.J.2
Biernacka, J.M.3
O'Kane, D.J.4
Cunningham, J.M.5
Wieben, E.D.6
Schaid, D.J.7
Drews, M.S.8
Courson, V.L.9
Snyder, K.A.10
-
18
-
-
33847282339
-
Analysis of Association Between the Serotonin Transporter and Antidepressant Response in a Large Clinical Sample
-
DOI 10.1016/j.biopsych.2006.07.017, PII S0006322306009413
-
J.B. Kraft, E.J. Peters, S.L. Slager, G.D. Jenkins, M.S. Reinalda, P.J. McGrath, and S.P. Hamilton Analysis of association between the serotonin transporter and antidepressant response in a large clinical sample Biol Psychiatry 61 2007 734 742 (Pubitemid 46330243)
-
(2007)
Biological Psychiatry
, vol.61
, Issue.6
, pp. 734-742
-
-
Kraft, J.B.1
Peters, E.J.2
Slager, S.L.3
Jenkins, G.D.4
Reinalda, M.S.5
McGrath, P.J.6
Hamilton, S.P.7
-
20
-
-
0642371335
-
Pharmacogenetics of antidepressant medication intolerance
-
DOI 10.1176/appi.ajp.160.10.1830
-
G.M. Murphy Jr., C. Kremer, H.E. Rodrigues, and A.F. Schatzberg Pharmacogenetics of antidepressant medication intolerance Am J Psychiatry 160 2003 1830 1835 (Pubitemid 41103318)
-
(2003)
American Journal of Psychiatry
, vol.160
, Issue.10
, pp. 1830-1835
-
-
Murphy Jr., G.M.1
Kremer, C.2
Rodrigues, H.E.3
Schatzberg, A.F.4
-
21
-
-
56349119282
-
Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice
-
M.A. Fox, C.L. Jensen, H.T. French, A.R. Stein, S.J. Huang, T.J. Tolliver, and D.L. Murphy Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice Psychopharmacology (Berl) 201 2008 203 218
-
(2008)
Psychopharmacology (Berl)
, vol.201
, pp. 203-218
-
-
Fox, M.A.1
Jensen, C.L.2
French, H.T.3
Stein, A.R.4
Huang, S.J.5
Tolliver, T.J.6
Murphy, D.L.7
-
22
-
-
70350216068
-
Genetics and irritable bowel syndrome: From genomics to intermediate phenotype and pharmacogenetics
-
M. Camilleri Genetics and irritable bowel syndrome: from genomics to intermediate phenotype and pharmacogenetics Dig Dis Sci 54 2009 2318 2324
-
(2009)
Dig Dis Sci
, vol.54
, pp. 2318-2324
-
-
Camilleri, M.1
-
23
-
-
23744490895
-
Population-based and family-based studies on the serotonin transporter gene polymorphisms and bipolar disorder: A systematic review and meta-analysis
-
DOI 10.1038/sj.mp.4001663
-
H.J. Cho, I. Meira-Lima, Q. Cordeiro, L. Michelon, P. Sham, H. Vallada, and D.A. Collier Population-based and family-based studies on the serotonin transporter gene polymorphisms and bipolar disorder: a systematic review and meta-analysis Mol Psychiatry 10 2005 771 781 (Pubitemid 41129050)
-
(2005)
Molecular Psychiatry
, vol.10
, Issue.8
, pp. 771-781
-
-
Cho, H.J.1
Meira-Lima, I.2
Cordeiro, Q.3
Michelon, L.4
Sham, P.5
Vallada, H.6
Collier, D.A.7
-
24
-
-
79953690576
-
Parent-of-origin effects of the serotonin transporter gene associated with autism
-
E. Kistner-Griffin, C.W. Brune, L.K. Davis, J.S. Sutcliffe, N.J. Cox, and E.H. Cook Jr. Parent-of-origin effects of the serotonin transporter gene associated with autism Am J Med Genet B Neuropsychiatr Genet 2010
-
(2010)
Am J Med Genet B Neuropsychiatr Genet
-
-
Kistner-Griffin, E.1
Brune, C.W.2
Davis, L.K.3
Sutcliffe, J.S.4
Cox, N.J.5
Cook Jr., E.H.6
-
25
-
-
27144520615
-
Meta-analysis reveals association between serotonin transporter gene STin2 VNTR polymorphism and schizophrenia
-
DOI 10.1038/sj.mp.4001690, PII 4001690
-
J.B. Fan, and P. Sklar Meta-analysis reveals association between serotonin transporter gene STin2 VNTR polymorphism and schizophrenia Mol Psychiatry 10 2005 928 938 891 (Pubitemid 41486485)
-
(2005)
Molecular Psychiatry
, vol.10
, Issue.10
, pp. 928-938
-
-
Fan, J.B.1
Sklar, P.2
-
26
-
-
68049126142
-
Accurate, large-scale genotyping of 5HTTLPR and flanking single nucleotide polymorphisms in an association study of depression, anxiety, and personality measures
-
N.R. Wray, M.R. James, S.D. Gordon, T. Dumenil, L. Ryan, W.L. Coventry, D.J. Statham, M.L. Pergadia, P.A. Madden, and A.C. Heath Accurate, large-scale genotyping of 5HTTLPR and flanking single nucleotide polymorphisms in an association study of depression, anxiety, and personality measures Biol Psychiatry 66 2009 468 476
-
(2009)
Biol Psychiatry
, vol.66
, pp. 468-476
-
-
Wray, N.R.1
James, M.R.2
Gordon, S.D.3
Dumenil, T.4
Ryan, L.5
Coventry, W.L.6
Statham, D.J.7
Pergadia, M.L.8
Madden, P.A.9
Heath, A.C.10
-
27
-
-
51449096819
-
Association of the serotonin transporter polymorphism and obsessive-compulsive disorder: Systematic review
-
M.H. Bloch, A. Landeros-Weisenberger, S. Sen, P. Dombrowski, B. Kelmendi, V. Coric, C. Pittenger, and J.F. Leckman Association of the serotonin transporter polymorphism and obsessive-compulsive disorder: systematic review Am J Med Genet B Neuropsychiatr Genet 147B 2008 850 858
-
(2008)
Am J Med Genet B Neuropsychiatr Genet
, vol.147
, pp. 850-858
-
-
Bloch, M.H.1
Landeros-Weisenberger, A.2
Sen, S.3
Dombrowski, P.4
Kelmendi, B.5
Coric, V.6
Pittenger, C.7
Leckman, J.F.8
-
28
-
-
67651121684
-
Candidate gene studies of ADHD: A meta-analytic review
-
I.R. Gizer, C. Ficks, and I.D. Waldman Candidate gene studies of ADHD: a meta-analytic review Hum Genet 126 2009 51 90
-
(2009)
Hum Genet
, vol.126
, pp. 51-90
-
-
Gizer, I.R.1
Ficks, C.2
Waldman, I.D.3
-
29
-
-
59849126325
-
Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery
-
B. Phillips-Bute, J.P. Mathew, J.A. Blumenthal, R.W. Morris, M.V. Podgoreanu, M. Smith, M. Stafford-Smith, H.P. Grocott, D.A. Schwinn, and M.F. Newman Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery Psychosom Med 70 2008 953 959
-
(2008)
Psychosom Med
, vol.70
, pp. 953-959
-
-
Phillips-Bute, B.1
Mathew, J.P.2
Blumenthal, J.A.3
Morris, R.W.4
Podgoreanu, M.V.5
Smith, M.6
Stafford-Smith, M.7
Grocott, H.P.8
Schwinn, D.A.9
Newman, M.F.10
-
30
-
-
77949272806
-
Genetic polymorphisms of the serotonin transporter, but not the 2a receptor or nitric oxide synthetase, are associated with pulmonary hypertension in chronic obstructive pulmonary disease
-
S. Ulrich, M. Hersberger, M. Fischler, Y. Nussbaumer-Ochsner, U. Treder, E.W. Russi, and R. Speich Genetic polymorphisms of the serotonin transporter, but not the 2a receptor or nitric oxide synthetase, are associated with pulmonary hypertension in chronic obstructive pulmonary disease Respiration 79 2010 288 295
-
(2010)
Respiration
, vol.79
, pp. 288-295
-
-
Ulrich, S.1
Hersberger, M.2
Fischler, M.3
Nussbaumer-Ochsner, Y.4
Treder, U.5
Russi, E.W.6
Speich, R.7
-
31
-
-
46049102966
-
The genetics of the serotonin transporter and irritable bowel syndrome
-
R. Colucci, C. Blandizzi, M. Bellini, N. Ghisu, M. Tonini, and M. Del Tacca The genetics of the serotonin transporter and irritable bowel syndrome Trends Mol Med 14 2008 295 304
-
(2008)
Trends Mol Med
, vol.14
, pp. 295-304
-
-
Colucci, R.1
Blandizzi, C.2
Bellini, M.3
Ghisu, N.4
Tonini, M.5
Del Tacca, M.6
-
32
-
-
25844521549
-
Influence of serotonin transporter gene polymorphism on depressive symptoms and new cardiac events after acute myocardial infarction
-
DOI 10.1016/j.ahj.2005.03.062, PII S0002870305004503
-
D. Nakatani, H. Sato, Y. Sakata, I. Shiotani, K. Kinjo, H. Mizuno, M. Shimizu, H. Ito, Y. Koretsune, and A. Hirayama Influence of serotonin transporter gene polymorphism on depressive symptoms and new cardiac events after acute myocardial infarction Am Heart J 150 2005 652 658 (Pubitemid 41396493)
-
(2005)
American Heart Journal
, vol.150
, Issue.4
, pp. 652-658
-
-
Nakatani, D.1
Sato, H.2
Sakata, Y.3
Shiotani, I.4
Kinjo, K.5
Mizuno, H.6
Shimizu, M.7
Ito, H.8
Koretsune, Y.9
Hirayama, A.10
Hori, M.11
-
33
-
-
0037624040
-
Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
-
DOI 10.1126/science.1083968
-
A. Caspi, K. Sugden, T.E. Moffitt, A. Taylor, I.W. Craig, H. Harrington, J. McClay, J. Mill, J. Martin, and A. Braithwaite Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene Science 301 2003 386 389 The first documentation in a prospective study showing that interviewed-based prior stress response correlated with SLC6A4 allele distributions in a G × E manner. (Pubitemid 36877077)
-
(2003)
Science
, vol.301
, Issue.5631
, pp. 386-389
-
-
Caspi, A.1
Sugden, K.2
Moffitt, T.E.3
Taylor, A.4
Craig, I.W.5
Harrington, H.6
McClay, J.7
Mill, J.8
Martin, J.9
Braithwaite, A.10
Poulton, R.11
-
34
-
-
38349150151
-
The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: Review and methodological analysis
-
R. Uher, and P. McGuffin The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis Mol Psychiatry 13 2008 131 146
-
(2008)
Mol Psychiatry
, vol.13
, pp. 131-146
-
-
Uher, R.1
McGuffin, P.2
-
35
-
-
38649099407
-
Targeting the murine serotonin transporter: Insights into human neurobiology
-
D.L. Murphy, and K.P. Lesch Targeting the murine serotonin transporter: insights into human neurobiology Nat Rev Neurosci 9 2008 85 94
-
(2008)
Nat Rev Neurosci
, vol.9
, pp. 85-94
-
-
Murphy, D.L.1
Lesch, K.P.2
-
36
-
-
77951854270
-
Genetic sensitivity to the environment: The case of the serotonin transporter gene and its implications for studying complex diseases and traits
-
A. Caspi, A.R. Hariri, A. Holmes, R. Uher, and T.E. Moffitt Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits Am J Psychiatry 167 2010 509 527
-
(2010)
Am J Psychiatry
, vol.167
, pp. 509-527
-
-
Caspi, A.1
Hariri, A.R.2
Holmes, A.3
Uher, R.4
Moffitt, T.E.5
-
37
-
-
79952033418
-
The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: Evidence of genetic moderation
-
K. Karg, M. Burmeister, K. Shedden, and S. Sen The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation Arch Gen Psychiatry 2011
-
(2011)
Arch Gen Psychiatry
-
-
Karg, K.1
Burmeister, M.2
Shedden, K.3
Sen, S.4
-
38
-
-
53649104153
-
The serotonin transporter genotype is associated with intermediate brain phenotypes that depend on the context of eliciting stressor
-
N.H. Kalin, S.E. Shelton, A.S. Fox, J. Rogers, T.R. Oakes, and R.J. Davidson The serotonin transporter genotype is associated with intermediate brain phenotypes that depend on the context of eliciting stressor Mol Psychiatry 13 2008 1021 1027
-
(2008)
Mol Psychiatry
, vol.13
, pp. 1021-1027
-
-
Kalin, N.H.1
Shelton, S.E.2
Fox, A.S.3
Rogers, J.4
Oakes, T.R.5
Davidson, R.J.6
-
39
-
-
40949084721
-
A study in male and female 5-HT transporter knockout rats: An animal model for anxiety and depression disorders
-
J.D. Olivier, M.G. Van Der Hart, R.P. Van Swelm, P.J. Dederen, J.R. Homberg, T. Cremers, P.M. Deen, E. Cuppen, A.R. Cools, and B.A. Ellenbroek A study in male and female 5-HT transporter knockout rats: an animal model for anxiety and depression disorders Neuroscience 152 2008 573 584
-
(2008)
Neuroscience
, vol.152
, pp. 573-584
-
-
Olivier, J.D.1
Van Der Hart, M.G.2
Van Swelm, R.P.3
Dederen, P.J.4
Homberg, J.R.5
Cremers, T.6
Deen, P.M.7
Cuppen, E.8
Cools, A.R.9
Ellenbroek, B.A.10
-
40
-
-
32844455397
-
Overexpression of the Drosophila vesicular monoamine transporter increases motor activity and courtship but decreases the behavioral response to cocaine
-
DOI 10.1038/sj.mp.4001742, PII 4001742
-
H.Y. Chang, A. Grygoruk, E.S. Brooks, L.C. Ackerson, N.T. Maidment, R.J. Bainton, and D.E. Krantz Overexpression of the Drosophila vesicular monoamine transporter increases motor activity and courtship but decreases the behavioral response to cocaine Mol Psychiatry 11 2006 99 113 (Pubitemid 43251092)
-
(2006)
Molecular Psychiatry
, vol.11
, Issue.1
, pp. 99-113
-
-
Chang, H.-Y.1
Grygoruk, A.2
Brooks, E.S.3
Ackerson, L.C.4
Maidment, N.T.5
Bainton, R.J.6
Krantz, D.E.7
-
41
-
-
79953267083
-
Serotonin transporter allelic variation in mothers predicts maternal sensitivity, behavior and attitudes toward 6-month-old infants
-
V. Mileva-Seitz, J. Kennedy, L. Atkinson, M. Steiner, R. Levitan, S.G. Matthews, M.J. Meaney, M.B. Sokolowski, and A.S. Fleming Serotonin transporter allelic variation in mothers predicts maternal sensitivity, behavior and attitudes toward 6-month-old infants Genes Brain Behav 2011
-
(2011)
Genes Brain Behav
-
-
Mileva-Seitz, V.1
Kennedy, J.2
Atkinson, L.3
Steiner, M.4
Levitan, R.5
Matthews, S.G.6
Meaney, M.J.7
Sokolowski, M.B.8
Fleming, A.S.9
-
42
-
-
41449100841
-
Serotonin Transporter (5-HTTLPR) Genotype and Amygdala Activation: A Meta-Analysis
-
DOI 10.1016/j.biopsych.2007.08.016, PII S0006322307008244
-
M.R. Munafo, S.M. Brown, and A.R. Hariri Serotonin transporter (5-HTTLPR) genotype and amygdala activation: a meta-analysis Biol Psychiatry 63 2008 852 857 (Pubitemid 351458448)
-
(2008)
Biological Psychiatry
, vol.63
, Issue.9
, pp. 852-857
-
-
Munafo, M.R.1
Brown, S.M.2
Hariri, A.R.3
-
43
-
-
71649097398
-
A candidate gene analysis of methylphenidate response in attention-deficit/hyperactivity disorder
-
J.J. McGough, J.T. McCracken, S.K. Loo, M. Manganiello, M.C. Leung, J.R. Tietjens, T. Trinh, S. Baweja, R. Suddath, and S.L. Smalley A candidate gene analysis of methylphenidate response in attention-deficit/hyperactivity disorder J Am Acad Child Adolesc Psychiatry 2009
-
(2009)
J Am Acad Child Adolesc Psychiatry
-
-
McGough, J.J.1
McCracken, J.T.2
Loo, S.K.3
Manganiello, M.4
Leung, M.C.5
Tietjens, J.R.6
Trinh, T.7
Baweja, S.8
Suddath, R.9
Smalley, S.L.10
-
44
-
-
53649090041
-
How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems
-
D.L. Murphy, M.A. Fox, K.R. Timpano, P.R. Moya, R. Ren-Patterson, A.M. Andrews, A. Holmes, K.P. Lesch, and J.R. Wendland How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems Neuropharmacology 55 2008 932 960 The most thorough review of the entire serotonergic system to date, with a special focus on mouse and human SLC6A4 contributions.
-
(2008)
Neuropharmacology
, vol.55
, pp. 932-960
-
-
Murphy, D.L.1
Fox, M.A.2
Timpano, K.R.3
Moya, P.R.4
Ren-Patterson, R.5
Andrews, A.M.6
Holmes, A.7
Lesch, K.P.8
Wendland, J.R.9
-
45
-
-
0345305851
-
Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders
-
DOI 10.1046/j.1601-1848.2003.00049.x
-
D.L. Murphy, G.R. Uhl, A. Holmes, R. Ren-Patterson, F.S. Hall, I. Sora, S. Detera-Wadleigh, and K.P. Lesch Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders Genes Brain Behav 2 2003 350 364 (Pubitemid 37463200)
-
(2003)
Genes, Brain and Behavior
, vol.2
, Issue.6
, pp. 350-364
-
-
Murphy, D.L.1
Uhl, G.R.2
Holmes, A.3
Ren-Patterson, R.4
Hall, F.S.5
Sora, I.6
Detera-Wadleigh, S.7
Lesch, K.-P.8
-
46
-
-
0344442889
-
The utility of the non-human primate model for studying gene by environment interactions in behavioral research
-
DOI 10.1046/j.1601-1848.2003.00051.x
-
C.S. Barr, T.K. Newman, M.L. Becker, C.C. Parker, M. Champoux, K.P. Lesch, D. Goldman, S.J. Suomi, and J.D. Higley The utility of the non-human primate; model for studying gene by environment interactions in behavioral research Genes Brain Behav 2 2003 336 340 (Pubitemid 37463198)
-
(2003)
Genes, Brain and Behavior
, vol.2
, Issue.6
, pp. 336-340
-
-
Barr, C.S.1
Newman, T.K.2
Becker, M.L.3
Parker, C.C.4
Champoux, M.5
Lesch, K.P.6
Goldman, D.7
Suomi, S.J.8
Higley, J.D.9
-
47
-
-
33646467211
-
Vulnerability to mild predator stress in serotonin transporter knockout mice
-
R. Adamec, P. Burton, J. Blundell, D.L. Murphy, and A. Holmes Vulnerability to mild predator stress in serotonin transporter knockout mice Behav Brain Res 170 2006 126 140
-
(2006)
Behav Brain Res
, vol.170
, pp. 126-140
-
-
Adamec, R.1
Burton, P.2
Blundell, J.3
Murphy, D.L.4
Holmes, A.5
-
48
-
-
2542447453
-
Serotonin transporter promoter and intron 2 polymorphisms: Relationship between allelic variants and gene expression
-
DOI 10.1016/j.biopsych.2004.01.029, PII S0006322304001350
-
D. Hranilovic, J. Stefulj, S. Schwab, M. Borrmann-Hassenbach, M. Albus, B. Jernej, and D. Wildenauer Serotonin transporter promoter and intron 2 polymorphisms: relationship between allelic variants and gene expression Biol Psychiatry 55 2004 1090 1094 Linkage association was found between higher vs. lower gene expression whrn Stin2 and 5HTTLPR were examined together. (Pubitemid 38680561)
-
(2004)
Biological Psychiatry
, vol.55
, Issue.11
, pp. 1090-1094
-
-
Hranilovic, D.1
Stefulj, J.2
Schwab, S.3
Borrmann-Hassenbach, M.4
Albus, M.5
Jernej, B.6
Wildenauer, D.7
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