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Volumn 46, Issue 12, 2012, Pages 1496-1513

Impact of SOD in eNOS uncoupling: A two-edged sword between hydrogen peroxide and peroxynitrite

Author keywords

dual role; eNOS uncoupling; hydrogen peroxide; peroxynitrite; SOD

Indexed keywords

BIOPTERIN; BORANE DERIVATIVE; CATALASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; NITRIC OXIDE; OXYGEN; PEROXYNITRITE; SUPEROXIDE DISMUTASE;

EID: 84868309300     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2012.731052     Document Type: Article
Times cited : (26)

References (92)
  • 1
    • 33645780634 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase in vascular disease: From marvel to menace
    • Forstermann U, Munzel T. Endothelial nitric oxide synthase in vascular disease: from marvel to menace. Circulation 2006;113:1708-1714.
    • (2006) Circulation , vol.113 , pp. 1708-1714
    • Forstermann, U.1    Munzel, T.2
  • 2
    • 2942610581 scopus 로고    scopus 로고
    • Dysfunction of endothelial nitric oxide synthase and atherosclerosis
    • DOI 10.1161/01.ATV.0000125114.88079.96
    • Kawashima S, Yokoyama M. Dysfunction of endothelial nitric oxide synthase and atherosclerosis. Arterioscler Thromb Vasc Biol 2004;24:998-1005. (Pubitemid 38737823)
    • (2004) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.24 , Issue.6 , pp. 998-1005
    • Kawashima, S.1    Yokoyama, M.2
  • 3
    • 80052268768 scopus 로고    scopus 로고
    • Modeling of biopterin-dependent pathways of eNOS for nitric oxide and superoxide production
    • Kar S, Kavdia M. Modeling of biopterin-dependent pathways of eNOS for nitric oxide and superoxide production. Free Radic Biol Med 2011;51:1411-1427.
    • (2011) Free Radic Biol Med , vol.51 , pp. 1411-1427
    • Kar, S.1    Kavdia, M.2
  • 4
    • 70249093891 scopus 로고    scopus 로고
    • Tetrahydrobiopterin, superoxide, and vascular dysfunction
    • Vasquez-Vivar J. Tetrahydrobiopterin, superoxide, and vascular dysfunction. Free Radic Biol Med 2009;47:1108-1119.
    • (2009) Free Radic Biol Med , vol.47 , pp. 1108-1119
    • Vasquez-Vivar, J.1
  • 5
    • 0029053451 scopus 로고
    • Superoxide radical and superoxide dismutases
    • Fridovich I. Superoxide radical and superoxide dismutases. Annu Rev Biochem 1995;64:97-112.
    • (1995) Annu Rev Biochem , vol.64 , pp. 97-112
    • Fridovich, I.1
  • 6
    • 68349135431 scopus 로고    scopus 로고
    • NO/peroxynitrite dynamics of high glucose-exposed HUVECs: Chemiluminescent measurement and computational model
    • Potdar S, Kavdia M. NO/peroxynitrite dynamics of high glucose-exposed HUVECs: chemiluminescent measurement and computational model. Microvasc Res 2009;78:191-198.
    • (2009) Microvasc Res , vol.78 , pp. 191-198
    • Potdar, S.1    Kavdia, M.2
  • 7
    • 80052263264 scopus 로고    scopus 로고
    • Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling
    • Al Ghouleh I, Khoo NK, Knaus UG, Griendling KK, Touyz RM, Thannickal VJ, et al. Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling. Free Radic Biol Med 2011;51:1271-1288.
    • (2011) Free Radic Biol Med , vol.51 , pp. 1271-1288
    • Al Ghouleh, I.1    Khoo, N.K.2    Knaus, U.G.3    Griendling, K.K.4    Touyz, R.M.5    Thannickal, V.J.6
  • 8
    • 24344499139 scopus 로고    scopus 로고
    • Hydrogen peroxide regulation of endothelial function: Origins, mechanisms, and consequences
    • DOI 10.1016/j.cardiores.2005.06.021, PII S000863630500324X
    • Cai H. Hydrogen peroxide regulation of endothelial function: origins, mechanisms, and consequences. Cardiovasc Res 2005; 68:26-36. (Pubitemid 41253553)
    • (2005) Cardiovascular Research , vol.68 , Issue.1 , pp. 26-36
    • Cai, H.1
  • 9
    • 36048938363 scopus 로고    scopus 로고
    • 2 and GPx concentrations
    • DOI 10.1080/10715760701625075, PII 782124528
    • Ng CF, Schafer FQ, Buettner GR, Rodgers VG. The rate of cellular hydrogen peroxide removal shows dependency on GSH: mathematical insight into in vivo H2O2 and GPx concentrations. Free Radic Res 2007;41:1201-1211. (Pubitemid 350090774)
    • (2007) Free Radical Research , vol.41 , Issue.11 , pp. 1201-1211
    • Ng, C.F.1    Schafer, F.Q.2    Buettner, G.R.3    Rodgers, V.G.J.4
  • 10
    • 33749005136 scopus 로고    scopus 로고
    • Nitroxidative, nitrosative, and nitrative stress: Kinetic predictions of reactive nitrogen species chemistry under biological conditions
    • DOI 10.1021/tx060061w
    • Lancaster JR Jr. Nitroxidative, nitrosative, and nitrative stress: kinetic predictions of reactive nitrogen species chemistry under biological conditions. Chem Res Toxicol 2006;19:1160-1174. (Pubitemid 44454032)
    • (2006) Chemical Research in Toxicology , vol.19 , Issue.9 , pp. 1160-1174
    • Lancaster Jr., J.R.1
  • 11
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
    • Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 1996; 271:C1424-C1437.
    • (1996) Am J Physiol , vol.271
    • Beckman, J.S.1    Koppenol, W.H.2
  • 13
    • 84855306513 scopus 로고    scopus 로고
    • Acute retinal ischemia inhibits endothelium-dependent nitric oxide-mediated dilation of retinal arterioles via enhanced superoxide production
    • Hein TW, Ren Y, Potts LB, Yuan Z, Kuo E, RosaRH Jr, Kuo L. Acute retinal ischemia inhibits endothelium-dependent nitric oxide-mediated dilation of retinal arterioles via enhanced superoxide production. Invest Ophthalmol Vis Sci 2012.
    • (2012) Invest Ophthalmol Vis Sci
    • Hein, T.W.1    Ren, Y.2    Potts, L.B.3    Yuan, Z.4    Kuo, E.5    Rosa Jr., R.H.6    Kuo, L.7
  • 15
    • 13944277696 scopus 로고    scopus 로고
    • i and microvessel permeability in the absence of adhesion: Role of reactive oxygen species
    • DOI 10.1152/ajpheart.00802.2004
    • Zhu L, Castranova V, He P. fMLP-stimulated neutrophils increase endothelial [Ca2?]i and microvessel permeability in the absence of adhesion: role of reactive oxygen species. Am J Physiol Heart Circ Physiol 2005;288:H1331-H1338. (Pubitemid 40270041)
    • (2005) American Journal of Physiology - Heart and Circulatory Physiology , vol.288 , Issue.3
    • Zhu, L.1    Castranova, V.2    He, P.3
  • 16
    • 70349845573 scopus 로고    scopus 로고
    • NOX and inflammation in the vascular adventitia
    • Csanyi G, Taylor WR, Pagano PJ. NOX and inflammation in the vascular adventitia. Free Radic Biol Med 2009;47: 1254-1266.
    • (2009) Free Radic Biol Med , vol.47 , pp. 1254-1266
    • Csanyi, G.1    Taylor, W.R.2    Pagano, P.J.3
  • 17
    • 0025732677 scopus 로고
    • Lipid peroxidation, protein thiol oxidation and DNA damage in hydrogen peroxide-induced injury to endothelial cells: Role of activation of poly(ADP-ribose)polymerase
    • Kirkland JB. Lipid peroxidation, protein thiol oxidation and DNA damage in hydrogen peroxide-induced injury to endothelial cells: role of activation of poly(ADP-ribose)polymerase. Biochim Biophys Acta 1991;1092:319-325.
    • (1991) Biochim Biophys Acta , vol.1092 , pp. 319-325
    • Kirkland, J.B.1
  • 18
    • 0346100520 scopus 로고    scopus 로고
    • Peroxynitrite reactivity with amino acids and proteins
    • DOI 10.1007/s00726-003-0018-8
    • Alvarez B, Radi R. Peroxynitrite reactivity with amino acids and proteins. Amino Acids 2003;25:295-311. (Pubitemid 38041267)
    • (2003) Amino Acids , vol.25 , Issue.3-4 , pp. 295-311
    • Alvarez, B.1    Radi, R.2
  • 21
    • 0037086565 scopus 로고    scopus 로고
    • The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: An EPR spin trapping study
    • DOI 10.1042/0264-6021:3620733
    • Vasquez-Vivar J, Martasek P, Whitsett J, Joseph J, Kalyanaraman B. The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study. Biochem J 2002;362:733-739. (Pubitemid 34242326)
    • (2002) Biochemical Journal , vol.362 , Issue.3 , pp. 733-739
    • Vasquez-Vivar, J.1    Martasek, P.2    Whitsett, J.3    Joseph, J.4    Kalyanaraman, B.5
  • 23
    • 41849144894 scopus 로고    scopus 로고
    • Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS
    • DOI 10.1152/ajpheart.00823.2007
    • Crabtree MJ, Smith CL, Lam G, Goligorsky MS, Gross SS. Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS. Am J Physiol Heart Circ Physiol 2008;294:H1530-H1540. (Pubitemid 351492501)
    • (2008) American Journal of Physiology - Heart and Circulatory Physiology , vol.294 , Issue.4
    • Crabtree, M.J.1    Smith, C.L.2    Lam, G.3    Goligorsky, M.S.4    Gross, S.S.5
  • 24
    • 0036271495 scopus 로고    scopus 로고
    • Cellular basis of endothelial dysfunction in small mesenteric arteries from spontaneously diabetic (db/db -/-) mice: Role of decreased tetrahydrobiopterin bioavailability
    • Pannirselvam M, Verma S, Anderson TJ, Triggle CR. Cellular basis of endothelial dysfunction in small mesenteric arteries from spontaneously diabetic (db/db-/-) mice: role of decreased tetrahydrobiopterin bioavailability. Br J Pharmacol 2002;136: 255-263. (Pubitemid 34587672)
    • (2002) British Journal of Pharmacology , vol.136 , Issue.2 , pp. 255-263
    • Pannirselvam, M.1    Verma, S.2    Anderson, T.J.3    Triggle, C.R.4
  • 25
    • 0029875833 scopus 로고    scopus 로고
    • High glucose induces antioxidant enzymes in human endothelial cells in culture. Evidence linking hyperglycemia and oxidative stress
    • Ceriello A, delloRusso P, Amstad P, Cerutti P. High glucose induces antioxidant enzymes in human endothelial cells in culture. Evidence linking hyperglycemia and oxidative stress. Diabetes 1996;45:471-477.
    • (1996) Diabetes , vol.45 , pp. 471-477
    • Ceriello, A.1    Dello Russo, P.2    Amstad, P.3    Cerutti, P.4
  • 26
  • 27
    • 0030846875 scopus 로고    scopus 로고
    • Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and superoxide anion production
    • Bouloumie A, Bauersachs J, Linz W, Scholkens BA, Wiemer G, Fleming I, Busse R. Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and superoxide anion production. Hypertension 1997;30:934-941. (Pubitemid 27441125)
    • (1997) Hypertension , vol.30 , Issue.4 , pp. 934-941
    • Bouloumie, A.1    Bauersachs, J.2    Linz, W.3    Scholkens, B.A.4    Wiemer, G.5    Fleming, I.6    Busse, R.7
  • 28
    • 6944237098 scopus 로고    scopus 로고
    • High glucose mediates pro-oxidant and antioxidant enzyme activities in coronary endothelial cells
    • DOI 10.1111/j.1462-8902.2004.00364.x
    • Weidig P, McMaster D, Bayraktutan U. High glucose mediates pro-oxidant and antioxidant enzyme activities in coronary endothelial cells. Diabetes Obes Metab 2004;6:432-441. (Pubitemid 39409794)
    • (2004) Diabetes, Obesity and Metabolism , vol.6 , Issue.6 , pp. 432-441
    • Weidig, P.1    McMaster, D.2    Bayraktutan, U.3
  • 30
    • 79954546899 scopus 로고    scopus 로고
    • High glucose concentration affects the oxidant-antioxidant balance in cultured mouse podocytes
    • Piwkowska A, Rogacka D, Audzeyenka I, Jankowski M, Angielski S. High glucose concentration affects the oxidant-antioxidant balance in cultured mouse podocytes. J Cell Biochem 2011;112:1661-1672.
    • (2011) J Cell Biochem , vol.112 , pp. 1661-1672
    • Piwkowska, A.1    Rogacka, D.2    Audzeyenka, I.3    Jankowski, M.4    Angielski, S.5
  • 31
    • 62949147248 scopus 로고    scopus 로고
    • Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells
    • Li X, Rong Y, Zhang M, Wang XL, LeMaire SA, Coselli JS, et al. Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells. Biochem Biophys Res Commun 2009;381:660-665.
    • (2009) Biochem Biophys Res Commun , vol.381 , pp. 660-665
    • Li, X.1    Rong, Y.2    Zhang, M.3    Wang, X.L.4    Lemaire, S.A.5    Coselli, J.S.6
  • 33
    • 0021804459 scopus 로고
    • Involvement of hydrogen peroxide and hydroxyl radical in the 'oxygen paradox': Reduction of creatine kinase release by catalase, allopurinol or deferoxamine, but not by superoxide dismutase
    • DOI 10.1016/S0022-2828(85)80067-5
    • Myers CL, Weiss SJ, Kirsh MM, Shlafer M. Involvement of hydrogen peroxide and hydroxyl radical in the 'oxygen paradox': reduction of creatine kinase release by catalase, allopurinolor deferoxamine, but not by superoxide dismutase. J Mol Cell Cardiol 1985;17:675-684. (Pubitemid 15065027)
    • (1985) Journal of Molecular and Cellular Cardiology , vol.17 , Issue.7 , pp. 675-684
    • Myers, C.L.1    Weiss, S.J.2    Kirsh, M.M.3    Shlafer, M.4
  • 34
    • 0024359606 scopus 로고
    • Reperfusion arrhythmias: Dose-related protection by anti-free radical interventions
    • Bernier M, Manning AS, Hearse DJ. Reperfusion arrhythmias: dose-related protection by anti-free radical interventions. Am J Physiol 1989;256:H1344- H1352.
    • (1989) Am J Physiol , vol.256
    • Bernier, M.1    Manning, A.S.2    Hearse, D.J.3
  • 35
    • 60249098253 scopus 로고    scopus 로고
    • Superoxide dismutase, lipid peroxidation, and bell-shaped dose response curves
    • McCord JM. Superoxide dismutase, lipid peroxidation, and bell-shaped dose response curves. Dose Response 2008;6: 223-238.
    • (2008) Dose Response , vol.6 , pp. 223-238
    • McCord, J.M.1
  • 36
    • 84555189342 scopus 로고    scopus 로고
    • Mathematical and computational models of oxidative and nitrosative stress
    • Kavdia M. Mathematical and computational models of oxidative and nitrosative stress. Crit Rev Biomed Eng 2011;39: 461-472.
    • (2011) Crit Rev Biomed Eng , vol.39 , pp. 461-472
    • Kavdia, M.1
  • 37
    • 82855181186 scopus 로고    scopus 로고
    • Differential effects of eNOS uncoupling on conduit and small arteries in GTPcyclohydrolase I-deficient hph-1 mice
    • d'Uscio LV, Smith LA, Katusic ZS. Differential effects of eNOS uncoupling on conduit and small arteries in GTPcyclohydrolase I-deficient hph-1 mice. Am J Physiol Heart Circ Physiol 2011;301:H2227-H2234.
    • (2011) Am J Physiol Heart Circ Physiol , vol.301
    • D'Uscio, L.V.1    Smith, L.A.2    Katusic, Z.S.3
  • 38
    • 47649122637 scopus 로고    scopus 로고
    • Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: Efficacy of recoupling nitric oxide synthase as a therapeutic strategy
    • Moens AL, Takimoto E, Tocchetti CG, Chakir K, Bedja D, Cormaci G, et al. Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy. Circulation 2008;117:2626-2636.
    • (2008) Circulation , vol.117 , pp. 2626-2636
    • Moens, A.L.1    Takimoto, E.2    Tocchetti, C.G.3    Chakir, K.4    Bedja, D.5    Cormaci, G.6
  • 39
    • 80051978810 scopus 로고    scopus 로고
    • Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling
    • Forstermann U, Li H. Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling. Br J Pharmacol 2011;164:213-223.
    • (2011) Br J Pharmacol , vol.164 , pp. 213-223
    • Forstermann, U.1    Li, H.2
  • 41
    • 31744450413 scopus 로고    scopus 로고
    • Alternative pathways as mechanism for the negative effects associated with overexpression of superoxide dismutase
    • DOI 10.1016/j.jtbi.2005.06.034, PII S0022519305002924
    • Kowald A, Lehrach H, Klipp E. Alternative pathways as mechanism for the negative effects associated with overexpression of superoxide dismutase. J Theor Biol 2006;238:828-840. (Pubitemid 43175833)
    • (2006) Journal of Theoretical Biology , vol.238 , Issue.4 , pp. 828-840
    • Kowald, A.1    Lehrach, H.2    Klipp, E.3
  • 42
    • 33749234188 scopus 로고    scopus 로고
    • 2 in Cells and Thereby Their Biological State
    • DOI 10.1016/j.freeradbiomed.2006.07.015, PII S0891584906004631
    • Buettner GR, Ng CF, Wang M, Rodgers VG, Schafer FQ. A new paradigm: manganese superoxide dismutase influences the production of H2O2 in cells and thereby their biological state. Free Radic Biol Med 2006;41:1338-1350. (Pubitemid 44479829)
    • (2006) Free Radical Biology and Medicine , vol.41 , Issue.8 , pp. 1338-1350
    • Buettner, G.R.1    Ng, C.F.2    Wang, M.3    Rodgers, V.G.J.4    Schafer, F.Q.5
  • 43
    • 0029908304 scopus 로고    scopus 로고
    • Lipid peroxidation in mitochondrial inner membranes. I. An integrative kinetic model
    • DOI 10.1016/S0891-5849(96)00185-2
    • Antunes F, Salvador A, Marinho HS, Alves R, Pinto RE. Lipid peroxidation in mitochondrial inner membranes. I. An integrative kinetic model. Free Radic Biol Med 1996;21:917-943. (Pubitemid 26365948)
    • (1996) Free Radical Biology and Medicine , vol.21 , Issue.7 , pp. 917-943
    • Antunes, F.1    Salvador, A.2    Marinho, H.S.3    Alves, R.4    Pinto, R.E.5
  • 44
    • 23744461597 scopus 로고    scopus 로고
    • Tyrosine nitration by superoxide and nitric oxide fluxes in biological systems: Modeling the impact of superoxide dismutase and nitric oxide diffusion
    • DOI 10.1016/j.freeradbiomed.2005.04.014, PII S0891584905002078
    • Quijano C, Romero N, Radi R. Tyrosine nitration by superoxide and nitric oxide fluxes in biological systems: modeling the impact of superoxide dismutase and nitric oxide diffusion. Free Radic Biol Med 2005;39:728-741. (Pubitemid 41139888)
    • (2005) Free Radical Biology and Medicine , vol.39 , Issue.6 , pp. 728-741
    • Quijano, C.1    Romero, N.2    Radi, R.3
  • 45
    • 33746313420 scopus 로고    scopus 로고
    • Theoretical analysis of biochemical pathways of nitric oxide release from vascular endothelial cells
    • DOI 10.1016/j.freeradbiomed.2006.05.009, PII S0891584906003200
    • Chen K, Popel AS. Theoretical analysis of biochemical pathways of nitric oxide release from vascular endothelial cells. Free Radic Biol Med 2006;41:668-680. (Pubitemid 44102718)
    • (2006) Free Radical Biology and Medicine , vol.41 , Issue.4 , pp. 668-680
    • Chen, K.1    Popel, A.S.2
  • 46
    • 0035966114 scopus 로고    scopus 로고
    • Differences in three kinetic parameters underpin the unique catalytic profiles of nitric-oxide synthases I, II, and III
    • Santolini J, Meade AL, Stuehr DJ. Differences in three kinetic parameters underpin the unique catalytic profiles of nitric-oxide synthases I, II, and III. J Biol Chem 2001;276: 48887-48898.
    • (2001) J Biol Chem , vol.276 , pp. 48887-48898
    • Santolini, J.1    Meade, A.L.2    Stuehr, D.J.3
  • 47
    • 5444247065 scopus 로고    scopus 로고
    • Redox function of tetrahydrobiopterin and effect of L-arginine on oxygen binding in endothelial nitric oxide synthase
    • DOI 10.1021/bi049026j
    • Berka V, Yeh HC, Gao D, Kiran F, Tsai AL. Redox function of tetrahydrobiopterin and effect of L-arginine on oxygen binding in endothelial nitric oxide synthase. Biochemistry 2004;43:13137-13148. (Pubitemid 39362782)
    • (2004) Biochemistry , vol.43 , Issue.41 , pp. 13137-13148
    • Berka, V.1    Yeh, H.-C.2    Gao, D.3    Kiran, F.4    Tsai, A.-L.5
  • 48
    • 0032488596 scopus 로고    scopus 로고
    • Comparative functioning of dihydro- and tetrahydropterins in supporting electron transfer, catalysis, and subunit dimerization in inducible nitric oxide synthase
    • DOI 10.1021/bi971944c
    • Presta A, Siddhanta U, Wu C, Sennequier N, Huang L, Abu-Soud HM, et al. Comparative functioning of dihydro-and tetrahydropterins in supporting electron transfer, catalysis, and subunit dimerization in inducible nitric oxide synthase. Biochemistry 1998;37:298-310. (Pubitemid 28049133)
    • (1998) Biochemistry , vol.37 , Issue.1 , pp. 298-310
    • Presta, A.1    Siddhanta, U.2    Wu, C.3    Sennequier, N.4    Huang, L.5    Abu-Soud, H.M.6    Erzurum, S.7    Stuehr, D.J.8
  • 49
    • 0034622567 scopus 로고    scopus 로고
    • Characterization of interactions among the heme center, tetrahydrobiopterin, and L-arginine binding sites of ferric eNOS using imidazole, cyanide, and nitric oxide as probes
    • DOI 10.1021/bi992769y
    • Berka V, Tsai AL. Characterization of interactions among the heme center, tetrahydrobiopterin, and L-arginine binding sites of ferric eNOS using imidazole, cyanide, and nitric oxide as probes. Biochemistry 2000;39:9373-9383. (Pubitemid 30626329)
    • (2000) Biochemistry , vol.39 , Issue.31 , pp. 9373-9383
    • Berka, V.1    Tsai, A.-L.2
  • 50
    • 0033621724 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite effects on the insulin secretion and viability of βTC3 cells
    • DOI 10.1114/1.258
    • Kavdia M, Stanfield JL, Lewis RS. Nitric oxide, superoxide, and peroxynitrite effects on the insulin secretion and viability of betaTC3 cells. Ann Biomed Eng 2000;28:102-109. (Pubitemid 30563024)
    • (2000) Annals of Biomedical Engineering , vol.28 , Issue.1 , pp. 102-109
    • Kavdia, M.1    Stanfield, J.L.2    Lewis, R.S.3
  • 53
    • 80052757568 scopus 로고    scopus 로고
    • Ascorbic acid and N-acetyl cysteine prevent uncoupling of nitric oxide synthase and increase tolerance to ischemia/reperfusion injury in diabetic rat heart
    • Okazaki T, Otani H, Shimazu T, Yoshioka K, Fujita M, Iwasaka T. Ascorbic acid and N-acetyl cysteine prevent uncoupling of nitric oxide synthase and increase tolerance to ischemia/reperfusion injury in diabetic rat heart. Free Radic Res 2011;45:1173-1183.
    • (2011) Free Radic Res , vol.45 , pp. 1173-1183
    • Okazaki, T.1    Otani, H.2    Shimazu, T.3    Yoshioka, K.4    Fujita, M.5    Iwasaka, T.6
  • 54
    • 13444262357 scopus 로고    scopus 로고
    • Tetrahydrobiopterin: Regulator of endothelial nitric oxide synthase in vascular disease
    • DOI 10.1016/j.tcm.2004.10.003, PII S1050173804001549
    • Channon KM. Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease. Trends Cardiovasc Med 2004;14:323-327. (Pubitemid 41110612)
    • (2004) Trends in Cardiovascular Medicine , vol.14 , Issue.8 , pp. 323-327
    • Channon, K.M.1
  • 55
    • 0025977048 scopus 로고
    • Signal transduction mechanisms involving nitric oxide
    • Ignarro LJ. Signal transduction mechanisms involving nitric oxide. Biochem Pharmacol 1991;41:485-490.
    • (1991) Biochem Pharmacol , vol.41 , pp. 485-490
    • Ignarro, L.J.1
  • 56
    • 3042569346 scopus 로고    scopus 로고
    • Contribution of nNOS- and eNOS-derived NO to microvascular smooth muscle NO exposure
    • DOI 10.1152/japplphysiol.00049.2004
    • Kavdia M, Popel AS. Contribution of nNOS-and eNOSderived NO to microvascular smooth muscle NO exposure. J Appl Physiol 2004;97:293-301. (Pubitemid 38802531)
    • (2004) Journal of Applied Physiology , vol.97 , Issue.1 , pp. 293-301
    • Kavdia, M.1    Popel, A.S.2
  • 57
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: Structure, function and inhibition
    • DOI 10.1042/0264-6021:3570593
    • Alderton WK, Cooper CE, Knowles RG. Nitric oxide synthases: structure, function and inhibition. Biochem J 2001;357: 593-615. (Pubitemid 32735142)
    • (2001) Biochemical Journal , vol.357 , Issue.3 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 58
    • 0035033713 scopus 로고    scopus 로고
    • In vivo control of soluble guanylate cyclase activation by nitric oxide: A kinetic analysis
    • Condorelli P, George SC. In vivo control of soluble guanylate cyclase activation by nitric oxide: a kinetic analysis. Biophys J 2001;80:2110-2119. (Pubitemid 32401977)
    • (2001) Biophysical Journal , vol.80 , Issue.5 , pp. 2110-2119
    • Condorelli, P.1    George, S.C.2
  • 59
    • 34648843079 scopus 로고    scopus 로고
    • On the biologic role of the reaction of NO with oxidized cytochrome C oxidase
    • DOI 10.1089/ars.2007.1677
    • Antunes F, Boveris A, Cadenas E. On the biologic role of the reaction of NO with oxidized cytochrome c oxidase. Antioxid Redox Signal 2007;9:1569-1579. (Pubitemid 47462962)
    • (2007) Antioxidants and Redox Signaling , vol.9 , Issue.10 , pp. 1569-1579
    • Antunes, F.1    Boveris, A.2    Cadenas, E.3
  • 60
    • 33746853424 scopus 로고    scopus 로고
    • A computational model for free radicals transport in the microcirculation
    • DOI 10.1089/ars.2006.8.1103
    • Kavdia M. A computational model for free radicals transport in the microcirculation. Antioxid Redox Signal 2006;8: 1103-1111. (Pubitemid 44182410)
    • (2006) Antioxidants and Redox Signaling , vol.8 , Issue.7-8 , pp. 1103-1111
    • Kavdia, M.1
  • 61
    • 57649183723 scopus 로고    scopus 로고
    • Impact of superoxide dismutase on nitric oxide and peroxynitrite levels in the microcirculation-a computational model
    • Chavez MD, Lakshmanan N, Kavdia M. Impact of superoxide dismutase on nitric oxide and peroxynitrite levels in the microcirculation-a computational model. Conf Proc IEEE Eng Med Biol Soc 2007;2007:1022-1026.
    • (2007) Conf Proc IEEE Eng Med Biol Soc , vol.2007 , pp. 1022-1026
    • Chavez, M.D.1    Lakshmanan, N.2    Kavdia, M.3
  • 62
    • 84862255347 scopus 로고    scopus 로고
    • Local Oxidative and nitrosative stress increases in the microcirculation during leukocytes-endothelial cell interactions
    • Kar S, Kavdia M. Local Oxidative and nitrosative stress increases in the microcirculation during leukocytes-endothelial cell interactions. PLoS One 2012;7:e38912.
    • (2012) PLoS One , vol.7
    • Kar, S.1    Kavdia, M.2
  • 63
    • 78249266312 scopus 로고    scopus 로고
    • A computational model for nitric oxide, nitrite and nitrate biotransport in the microcirculation: Effect of reduced nitric oxide consumption by red blood cells and blood velocity
    • Deonikar P, Kavdia M. A computational model for nitric oxide, nitrite and nitrate biotransport in the microcirculation: effect of reduced nitric oxide consumption by red blood cells and blood velocity. Microvasc Res 2010;80:464-476.
    • (2010) Microvasc Res , vol.80 , pp. 464-476
    • Deonikar, P.1    Kavdia, M.2
  • 64
    • 0038368883 scopus 로고    scopus 로고
    • Modeling the influence of superoxide dismutase on superoxide and nitric oxide interactions, including reversible inhibition of oxygen consumption
    • DOI 10.1016/S0891-5849(03)00178-3
    • Buerk DG, Lamkin-Kennard K, Jaron D. Modeling the influence of superoxide dismutase on superoxide and nitric oxide interactions, including reversible inhibition of oxygen consumption. Free Radic Biol Med 2003;34:1488-1503. (Pubitemid 36570421)
    • (2003) Free Radical Biology and Medicine , vol.34 , Issue.11 , pp. 1488-1503
    • Buerk, D.G.1    Lamkin-Kennard, K.2    Jaron, D.3
  • 65
    • 0038604446 scopus 로고    scopus 로고
    • Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: Implications for uncoupling endothelial nitric-oxide synthase
    • DOI 10.1074/jbc.M302227200
    • Kuzkaya N, Weissmann N, Harrison DG, Dikalov S. Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase. J Biol Chem 2003;278:22546-22554. (Pubitemid 36830310)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.25 , pp. 22546-22554
    • Kuzkaya, N.1    Weissmann, N.2    Harrison, D.G.3    Dikalov, S.4
  • 66
    • 0035724654 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II/janus kinase 2-dependent pathway
    • Cai H, Davis ME, Drummond GR, Harrison DG. Induction of endothelial NO synthase by hydrogen peroxide via a Ca(2f)/calmodulin-dependent protein kinase II/janus kinase 2-dependent pathway. Arterioscler Thromb Vasc Biol 2001;21: 1571-1576. (Pubitemid 34215574)
    • (2001) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.21 , Issue.10 , pp. 1571-1576
    • Cai, H.1    Davis, M.E.2    Drummond, G.R.3    Harrison, D.G.4
  • 67
    • 0037155131 scopus 로고    scopus 로고
    • Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway
    • DOI 10.1074/jbc.M109107200
    • Thomas SR, Chen K, Keaney JF Jr. Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway. J Biol Chem 2002;277: 6017-6024. (Pubitemid 34968385)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.8 , pp. 6017-6024
    • Thomas, S.R.1    Chen, K.2    Keaney Jr., J.F.3
  • 68
    • 4043159127 scopus 로고    scopus 로고
    • Inactivation of human Cu,Zn superoxide dismutase by peroxynitrite and formation of histidinyl radical
    • DOI 10.1016/j.freeradbiomed.2004.06.006, PII S0891584904004599
    • Alvarez B, Demicheli V, Duran R, Trujillo M, Cervenansky C, Freeman BA, Radi R. Inactivation of human Cu,Zn superoxide dismutase by peroxynitrite and formation of histidinyl radical. Free Radic Biol Med 2004;37:813-822. (Pubitemid 39078553)
    • (2004) Free Radical Biology and Medicine , vol.37 , Issue.6 , pp. 813-822
    • Alvarez, B.1    Demicheli, V.2    Duran, R.3    Trujillo, M.4    Cervenansky, C.5    Freeman, B.A.6    Radi, R.7
  • 69
    • 0032501998 scopus 로고    scopus 로고
    • Peroxynitrite-mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues
    • DOI 10.1021/bi971894b
    • MacMillan-Crow LA, Crow JP, Thompson JA. Peroxynitritemediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues. Biochemistry 1998;37:1613-1622. (Pubitemid 28093677)
    • (1998) Biochemistry , vol.37 , Issue.6 , pp. 1613-1622
    • MacMillan-Crow, L.A.1    Crow, J.P.2    Thompson, J.A.3
  • 70
    • 80052266526 scopus 로고    scopus 로고
    • Cross talk between mitochondria and NADPH oxidases
    • Dikalov S. Cross talk between mitochondria and NADPH oxidases. Free Radic Biol Med 2011;51:1289-1301.
    • (2011) Free Radic Biol Med , vol.51 , pp. 1289-1301
    • Dikalov, S.1
  • 71
    • 85047690420 scopus 로고    scopus 로고
    • Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression
    • DOI 10.1172/JCI200317786
    • Alp NJ, Mussa S, Khoo J, Cai S, Guzik T, Jefferson A, et al. Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression. J Clin Invest 2003;112:725-735. (Pubitemid 38057713)
    • (2003) Journal of Clinical Investigation , vol.112 , Issue.5 , pp. 725-735
    • Alp, N.J.1    Mussa, S.2    Khoo, J.3    Cai, S.4    Guzik, T.5    Jefferson, A.6    Goh, N.7    Rockett, K.A.8    Channon, K.M.9
  • 75
    • 78650389551 scopus 로고    scopus 로고
    • Oxidation of histidine residues in copper-zinc superoxide dismutase by bicarbonate-stimulated peroxidase and thiol oxidase activities: Pulse EPR and NMR studies
    • Chandran K, McCracken J, Peterson FC, Antholine WE, Volkman BF, Kalyanaraman B. Oxidation of histidine residues in copper-zinc superoxide dismutase by bicarbonate-stimulated peroxidase and thiol oxidase activities: pulse EPR and NMR studies. Biochemistry 2010;49:10616-10622.
    • (2010) Biochemistry , vol.49 , pp. 10616-10622
    • Chandran, K.1    McCracken, J.2    Peterson, F.C.3    Antholine, W.E.4    Volkman, B.F.5    Kalyanaraman, B.6
  • 76
    • 0027742538 scopus 로고
    • Endothelial activation by hydrogen peroxide: Selective increases of intercellular adhesion molecule-1 and major histocompatibility complex class I
    • Bradley JR, Johnson DR, Pober JS. Endothelial activation by hydrogen peroxide. Selective increases of intercellular adhesion molecule-1 and major histocompatibility complex class I. Am J Pathol 1993;142:1598-1609. (Pubitemid 24058146)
    • (1993) American Journal of Pathology , vol.142 , Issue.5 , pp. 1598-1609
    • Bradley, J.R.1    Johnson, D.R.2    Pober, J.S.3
  • 79
    • 33646849480 scopus 로고    scopus 로고
    • Hydrogen peroxide-mediated necrosis induction in HUVECs is associated with an atypical pattern of caspase-3 cleavage
    • DOI 10.1016/j.yexcr.2006.02.005, PII S0014482706000504
    • Csordas A, Wick G, Bernhard D. Hydrogen peroxidemediated necrosis induction in HUVECs is associated with an atypical pattern of caspase-3 cleavage. Exp Cell Res 2006;312:1753-1764. (Pubitemid 43776009)
    • (2006) Experimental Cell Research , vol.312 , Issue.10 , pp. 1753-1764
    • Csordas, A.1    Wick, G.2    Bernhard, D.3
  • 80
    • 80053912911 scopus 로고    scopus 로고
    • Effects of Rhein lysinate on H2O2-induced cellular senescence of human umbilical vascular endothelial cells
    • Lin YJ, Zhen YZ, Wei J, Liu B, Yu ZY, Hu G. Effects of Rhein lysinate on H2O2-induced cellular senescence of human umbilical vascular endothelial cells. Acta Pharmacol Sin 2011;32:1246-1252.
    • (2011) Acta Pharmacol Sin , vol.32 , pp. 1246-1252
    • Lin, Y.J.1    Zhen, Y.Z.2    Wei, J.3    Liu, B.4    Yu, Z.Y.5    Hu, G.6
  • 81
    • 67349209487 scopus 로고    scopus 로고
    • Role of PPAR-beta in hydrogen peroxide-induced apoptosis in human umbilical vein endothelial cells
    • Jiang B, Liang P, Zhang B, Song J, Huang X, Xiao X. Role of PPAR-beta in hydrogen peroxide-induced apoptosis in human umbilical vein endothelial cells. Atherosclerosis 2009; 204:353-358.
    • (2009) Atherosclerosis , vol.204 , pp. 353-358
    • Jiang, B.1    Liang, P.2    Zhang, B.3    Song, J.4    Huang, X.5    Xiao, X.6
  • 82
    • 0036468241 scopus 로고    scopus 로고
    • Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate
    • DOI 10.1016/S0891-5849(01)00777-8, PII S0891584901007778
    • Patel KB, Stratford MR, Wardman P, Everett SA. Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate. Free Radic Biol Med 2002;32:203-211. (Pubitemid 34119398)
    • (2002) Free Radical Biology and Medicine , vol.32 , Issue.3 , pp. 203-211
    • Patel, K.B.1    Stratford, M.R.L.2    Wardman, P.3    Everett, S.A.4
  • 83
    • 84856226956 scopus 로고    scopus 로고
    • Propofol protects against high glucose-induced endothelial dysfunction in human umbilical vein endothelial cells
    • Zhu M, Chen J, Tan Z, Wang J. Propofol protects against high glucose-induced endothelial dysfunction in human umbilical vein endothelial cells. Anesth Analg 2012;114:303-309.
    • (2012) Anesth Analg , vol.114 , pp. 303-309
    • Zhu, M.1    Chen, J.2    Tan, Z.3    Wang, J.4
  • 84
    • 0035814951 scopus 로고    scopus 로고
    • Endothelial regulation of vasomotion in ApoE-deficient mice: Implications for interactions between peroxynitrite and tetrahydrobiopterin
    • Laursen JB, Somers M, Kurz S, McCann L, Warnholtz A, Freeman BA, et al. Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin. Circulation 2001;103: 1282-1288. (Pubitemid 32221353)
    • (2001) Circulation , vol.103 , Issue.9 , pp. 1282-1288
    • Laursen, J.B.1    Somers, M.2    Kurz, S.3    McCann, L.4    Warnholtz, A.5    Freeman, B.A.6    Tarpey, M.7    Fukai, T.8    Harrison, D.G.9
  • 85
    • 0036199685 scopus 로고    scopus 로고
    • Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite
    • DOI 10.1172/JCI200214442
    • Zou MH, Shi C, Cohen RA. Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite. J Clin Invest 2002;109:817-826. (Pubitemid 34263158)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.6 , pp. 817-826
    • Zou, M.-H.1    Shi, C.2    Cohen, R.A.3
  • 86
    • 80051698652 scopus 로고    scopus 로고
    • Superoxide induces endothelial nitric-oxide synthase protein thiyl radical formation, a novel mechanism regulating eNOS function and coupling
    • Chen CA, Lin CH, Druhan LJ, Wang TY, Chen YR, Zweier JL. Superoxide induces endothelial nitric-oxide synthase protein thiyl radical formation, a novel mechanism regulating eNOS function and coupling. J Biol Chem 2011;286: 29098-29107.
    • (2011) J Biol Chem , vol.286 , pp. 29098-29107
    • Chen, C.A.1    Lin, C.H.2    Druhan, L.J.3    Wang, T.Y.4    Chen, Y.R.5    Zweier, J.L.6
  • 87
    • 0035990855 scopus 로고    scopus 로고
    • Free radical profiles in an encapsulated pancreatic cell matrix model
    • DOI 10.1114/1.1481054
    • Kavdia M, Lewis RS. Free radical profiles in an encapsulated pancreatic cell matrix model. Ann Biomed Eng 2002;30: 721-730. (Pubitemid 34783439)
    • (2002) Annals of Biomedical Engineering , vol.30 , Issue.5 , pp. 721-730
    • Kavdia, M.1    Lewis, R.S.2
  • 89
    • 36849023528 scopus 로고    scopus 로고
    • Enhanced mitochondrial superoxide in hyperglycemic endothelial cells: Direct measurements and formation of hydrogen peroxide and peroxynitrite
    • DOI 10.1152/ajpheart.00761.2007
    • Quijano C, Castro L, Peluffo G, Valez V, Radi R. Enhanced mitochondrial superoxide in hyperglycemic endothelial cells: direct measurements and formation of hydrogen peroxide and peroxynitrite. Am J Physiol Heart Circ Physiol 2007;293: H3404-H3414. (Pubitemid 350230882)
    • (2007) American Journal of Physiology - Heart and Circulatory Physiology , vol.293 , Issue.6
    • Quijano, C.1    Castro, L.2    Peluffo, G.3    Valez, V.4    Radi, R.5
  • 90
    • 3242774397 scopus 로고    scopus 로고
    • 2 permeation through cytoplasmic and peroxisomal membranes: Comparison with experimental data
    • DOI 10.1016/j.bbagen.2004.04.011, PII S0304416504001072
    • Makino N, Sasaki K, Hashida K, Sakakura Y. A metabolic model describing the H2O2 elimination by mammalian cells including H2O2 permeation through cytoplasmic and peroxisomal membranes: comparison with experimental data. Biochim Biophys Acta 2004;1673:149-159. (Pubitemid 38981768)
    • (2004) Biochimica et Biophysica Acta - General Subjects , vol.1673 , Issue.3 , pp. 149-159
    • Makino, N.1    Sasaki, K.2    Hashida, K.3    Sakakura, Y.4
  • 91
    • 49449117608 scopus 로고    scopus 로고
    • Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia
    • Qutub AA, Popel AS. Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia. Mol Cell Biol 2008;28:5106-5119.
    • (2008) Mol Cell Biol , vol.28 , pp. 5106-5119
    • Qutub, A.A.1    Popel, A.S.2
  • 92
    • 0041589260 scopus 로고    scopus 로고
    • The autoxidation of tetrahydrobiopterin revisited: Proof of superoxide formation from reaction of tetrahydrobiopterin with molecular oxygen
    • DOI 10.1074/jbc.M211779200
    • Kirsch M, Korth HG, Stenert V, Sustmann R, de Groot H. The autoxidation of tetrahydrobiopterin revisited. Proof of superoxide formation from reaction of tetrahydrobiopterin with molecular oxygen. J Biol Chem 2003;278: 24481-24490. (Pubitemid 37548600)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.27 , pp. 24481-24490
    • Kirsch, M.1    Korth, H.-G.2    Stenert, V.3    Sustmann, R.4    De Groot, H.5


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