Ascorbic acid and N-acetyl cysteine prevent uncoupling of nitric oxide synthase and increase tolerance to ischemia/reperfusion injury in diabetic rat heart

Free Radical Research

Volumn 45, Issue 10, 2011, Pages 1173-1183

  Okazaki, Toru ^a   Otani, Hajime ^a   Shimazu, Takayuki ^a   Yoshioka, Kei ^a   Fujita, Masanori ^a   Iwasaka, Toshiji ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Cardioprotection; Diabetes mellitus; Ischemia; Nitric oxide synthase; Reperfusion; Tetrahydrobiopterin

Indexed keywords

3 NITROTYROSINE; ACETYLCYSTEINE; ASCORBIC ACID; DIHYDROBIOPTERIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; SUPEROXIDE; TETRAHYDROBIOPTERIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOAVAILABILITY; CELL PROTECTION; CONTROLLED STUDY; HEART INFARCTION SIZE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MALE; NONHUMAN; RAT; REPERFUSION INJURY; STREPTOZOCIN DIABETES;

ACETYLCYSTEINE; ANIMALS; ASCORBIC ACID; BIOPTERIN; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

RATTUS;

EID: 80052757568     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2011.605361     Document Type: Article

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