-
1
-
-
85047690420
-
Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression
-
Alp NJ, Mussa S, Khoo J, Cai S, Guzik T, Jefferson A, Goh N, Rockett KA, Channon KM. Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression. J Clin Invest 112: 725-735, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 725-735
-
-
Alp, N.J.1
Mussa, S.2
Khoo, J.3
Cai, S.4
Guzik, T.5
Jefferson, A.6
Goh, N.7
Rockett, K.A.8
Channon, K.M.9
-
2
-
-
45849101717
-
GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function
-
Antoniades C, Shirodaria C, Van Assche T, Cunnington C, Tegeder I, Lotsch J, Guzik TJ, Leeson P, Diesch J, Tousoulis D, Stefanadis C, Costigan M, Woolf CJ, Alp NJ, Channon KM. GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function. J Am Coll Cardiol 52: 158-165, 2008.
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 158-165
-
-
Antoniades, C.1
Shirodaria, C.2
van Assche, T.3
Cunnington, C.4
Tegeder, I.5
Lotsch, J.6
Guzik, T.J.7
Leeson, P.8
Diesch, J.9
Tousoulis, D.10
Stefanadis, C.11
Costigan, M.12
Woolf, C.J.13
Alp, N.J.14
Channon, K.M.15
-
3
-
-
0026354381
-
Hydrogen peroxide- induced pulmonary vasodilation: Role of guanosine 3',5'-cyclic monophosphate
-
Burke-Wolin T, Abate CJ, Wolin MS, Gurtner GH. Hydrogen peroxide- induced pulmonary vasodilation: role of guanosine 3',5'-cyclic monophosphate. Am J Physiol Lung Cell Mol Physiol 261: L393-L398, 1991.
-
(1991)
Am J Physiol Lung Cell Mol Physiol
, vol.261
-
-
Burke-Wolin, T.1
Abate, C.J.2
Wolin, M.S.3
Gurtner, G.H.4
-
4
-
-
55249112287
-
Phosphorylation of endothelial nitric-oxide synthase regulates superoxide generation from the enzyme
-
Chen CA, Druhan LJ, Varadharaj S, Chen YR, Zweier JL. Phosphorylation of endothelial nitric-oxide synthase regulates superoxide generation from the enzyme. J Biol Chem 283: 27038-27047, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 27038-27047
-
-
Chen, C.A.1
Druhan, L.J.2
Varadharaj, S.3
Chen, Y.R.4
Zweier, J.L.5
-
5
-
-
0028813306
-
Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries
-
Cosentino F, Katusic ZS. Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries. Circulation 91: 139-144, 1995.
-
(1995)
Circulation
, vol.91
, pp. 139-144
-
-
Cosentino, F.1
Katusic, Z.S.2
-
6
-
-
0035045172
-
Reactive oxygen species mediate endothelium-dependent relaxations in tetrahydrobiopterin- deficient mice
-
Cosentino F, Barker JE, Brand MP, Heales SJ, Werner ER, Tippins JR, West N, Channon KM, Volpe M, Lüscher TF. Reactive oxygen species mediate endothelium-dependent relaxations in tetrahydrobiopterin- deficient mice. Arterioscler Thromb Vasc Biol 21: 496-502, 2001.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 496-502
-
-
Cosentino, F.1
Barker, J.E.2
Brand, M.P.3
Heales, S.J.4
Werner, E.R.5
Tippins, J.R.6
West, N.7
Channon, K.M.8
Volpe, M.9
Lüscher, T.F.10
-
7
-
-
41849144894
-
Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS
-
Crabtree MJ, Smith CL, Lam G, Goligorsky MS, Gross SS. Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS. Am J Physiol Heart Circ Physiol 294: H1530-H1540, 2008.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Crabtree, M.J.1
Smith, C.L.2
Lam, G.3
Goligorsky, M.S.4
Gross, S.S.5
-
8
-
-
0035718119
-
Mechanism of endothelial dysfunction in apolipoprotein E-deficient mice
-
D'Uscio LV, Baker TA, Mantilla CB, Smith L, Weiler D, Sieck GC, Katusic ZS. Mechanism of endothelial dysfunction in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 21: 1017-1022, 2001.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1017-1022
-
-
D'uscio, L.V.1
Baker, T.A.2
Mantilla, C.B.3
Smith, L.4
Weiler, D.5
Sieck, G.C.6
Katusic, Z.S.7
-
9
-
-
0037428209
-
Longterm vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity
-
d'Uscio LV, Milstien S, Richardson D, Smith L, Katusic ZS. Longterm vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity. Circ Res 92: 88-95, 2003.
-
(2003)
Circ Res
, vol.92
, pp. 88-95
-
-
D'uscio, L.V.1
Milstien, S.2
Richardson, D.3
Smith, L.4
Katusic, Z.S.5
-
10
-
-
33744940788
-
Increased vascular biosynthesis of tetrahydrobiopterin in apolipoprotein E-deficient mice
-
d'Uscio LV, Katusic ZS. Increased vascular biosynthesis of tetrahydrobiopterin in apolipoprotein E-deficient mice. Am J Physiol Heart Circ Physiol 290: H2466-H2471, 2006.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
-
-
D'uscio, L.V.1
Katusic, Z.S.2
-
11
-
-
34247853270
-
Essential role of endothelial nitric oxide synthase in vascular effects of erythropoietin
-
d'Uscio LV, Smith LA, Santhanam AV, Richardson D, Nath KA, Katusic ZS. Essential role of endothelial nitric oxide synthase in vascular effects of erythropoietin. Hypertension 49: 1142-1148, 2007.
-
(2007)
Hypertension
, vol.49
, pp. 1142-1148
-
-
D'uscio, L.V.1
Smith, L.A.2
Santhanam, A.V.3
Richardson, D.4
Nath, K.A.5
Katusic, Z.S.6
-
12
-
-
77950502455
-
Erythropoietin increases expression and function of vascular copper- and zinc-containing superoxide dismutase
-
d'Uscio LV, Smith LA, Katusic ZS. Erythropoietin increases expression and function of vascular copper- and zinc-containing superoxide dismutase. Hypertension 55: 998-1004, 2010.
-
(2010)
Hypertension
, vol.55
, pp. 998-1004
-
-
D'uscio, L.V.1
Smith, L.A.2
Katusic, Z.S.3
-
13
-
-
33747404190
-
Role of extracellular superoxide dismutase in hypertension
-
Gongora MC, Qin Z, Laude K, Kim HW, McCann L, Folz JR, Dikalov S, Fukai T, Harrison DG. Role of extracellular superoxide dismutase in hypertension. Hypertension 48: 473-481, 2006.
-
(2006)
Hypertension
, vol.48
, pp. 473-481
-
-
Gongora, M.C.1
Qin, Z.2
Laude, K.3
Kim, H.W.4
McCann, L.5
Folz, J.R.6
Dikalov, S.7
Fukai, T.8
Harrison, D.G.9
-
14
-
-
0027101755
-
Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle
-
Gross SS, Levi R. Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle. J Biol Chem 267: 25722-25729, 1992.
-
(1992)
J Biol Chem
, vol.267
, pp. 25722-25729
-
-
Gross, S.S.1
Levi, R.2
-
15
-
-
0028027522
-
Molecular characterization of HPH-1: A mouse mutant deficient in GTP cyclohydrolase I activity
-
Gutlich M, Ziegler I, Witter K, Hemmens B, Hultner L, McDonald JD, Werner T, Rodl W, Bacher A. Molecular characterization of HPH-1: a mouse mutant deficient in GTP cyclohydrolase I activity. Biochem Biophys Res Commun 203: 1675-1681, 1994.
-
(1994)
Biochem Biophys Res Commun
, vol.203
, pp. 1675-1681
-
-
Gutlich, M.1
Ziegler, I.2
Witter, K.3
Hemmens, B.4
Hultner, L.5
McDonald, J.D.6
Werner, T.7
Rodl, W.8
Bacher, A.9
-
16
-
-
0028138916
-
Endothelial dysfunction in atherosclerosis
-
Harrison DG. Endothelial dysfunction in atherosclerosis. Basic Res Cardiol 89, Suppl 1: 87-102, 1994.
-
(1994)
Basic Res Cardiol
, vol.89
, Issue.1
, pp. 87-102
-
-
Harrison, D.G.1
-
17
-
-
58149138838
-
Vascular protection by tetrahydrobiopterin: Progress and therapeutic prospects
-
Katusic ZS, d'Uscio LV, Nath KA. Vascular protection by tetrahydrobiopterin: progress and therapeutic prospects. Trends Pharmacol Sci 30: 48-54, 2009.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 48-54
-
-
Katusic, Z.S.1
D'uscio, L.V.2
Nath, K.A.3
-
18
-
-
3242678162
-
Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
-
Khoo JP, Nicoli T, Alp NJ, Fullerton J, Flint J, Channon KM. Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse. Mol Genet Metab 82: 251-254, 2004.
-
(2004)
Mol Genet Metab
, vol.82
, pp. 251-254
-
-
Khoo, J.P.1
Nicoli, T.2
Alp, N.J.3
Fullerton, J.4
Flint, J.5
Channon, K.M.6
-
19
-
-
17744386526
-
Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension
-
Khoo JP, Zhao L, Alp NJ, Bendall JK, Nicoli T, Rockett K, Wilkins MR, Channon KM. Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension. Circulation 111: 2126-2133, 2005.
-
(2005)
Circulation
, vol.111
, pp. 2126-2133
-
-
Khoo, J.P.1
Zhao, L.2
Alp, N.J.3
Bendall, J.K.4
Nicoli, T.5
Rockett, K.6
Wilkins, M.R.7
Channon, K.M.8
-
20
-
-
0032585617
-
The effects of oxygen radicals on the activity of nitric oxide synthase and guanylate cyclase
-
Kim SM, Byun JS, Jung YD, Kang IC, Choi SY, Lee KY. The effects of oxygen radicals on the activity of nitric oxide synthase and guanylate cyclase. Exp Mol Med 30: 221-226, 1998.
-
(1998)
Exp Mol Med
, vol.30
, pp. 221-226
-
-
Kim, S.M.1
Byun, J.S.2
Jung, Y.D.3
Kang, I.C.4
Choi, S.Y.5
Lee, K.Y.6
-
21
-
-
0037399439
-
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension
-
Landmesser U, Dikalov S, Price SR, McCann L, Fukai T, Holland SM, Mitch WE, Harrison DG. Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest 111: 1201-1209, 2003.
-
(2003)
J Clin Invest
, vol.111
, pp. 1201-1209
-
-
Landmesser, U.1
Dikalov, S.2
Price, S.R.3
McCann, L.4
Fukai, T.5
Holland, S.M.6
Mitch, W.E.7
Harrison, D.G.8
-
22
-
-
0021218456
-
Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species
-
Marklund SL. Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species. Biochem J 222: 649-655, 1984.
-
(1984)
Biochem J
, vol.222
, pp. 649-655
-
-
Marklund, S.L.1
-
23
-
-
0034054493
-
Enhanced electron flux and reduced calmodulin dissociation may explain "calcium-independent" eNOS activation by phosphorylation
-
McCabe TJ, Fulton D, Roman LJ, Sessa WC. Enhanced electron flux and reduced calmodulin dissociation may explain "calcium-independent" eNOS activation by phosphorylation. J Biol Chem 275: 6123-6128, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 6123-6128
-
-
McCabe, T.J.1
Fulton, D.2
Roman, L.J.3
Sessa, W.C.4
-
24
-
-
0023881310
-
Biochemical defect of the hph-1 mouse mutant is a deficiency in GTPcyclohydrolase activity
-
McDonald JD, Cotton RG, Jennings I, Ledley FD, Woo SL, Bode VC. Biochemical defect of the hph-1 mouse mutant is a deficiency in GTPcyclohydrolase activity. J Neurochem 50: 655-657, 1988.
-
(1988)
J Neurochem
, vol.50
, pp. 655-657
-
-
McDonald, J.D.1
Cotton, R.G.2
Jennings, I.3
Ledley, F.D.4
Woo, S.L.5
Bode, V.C.6
-
25
-
-
0034235409
-
Impaired nitric oxide production in coronary endothelial cells of the spontaneously diabetic BB rat is due to tetrahydrobiopterin deficiency
-
Meininger CJ, Marinos RS, Hatakeyama K, Martinez-Zaguilan R, Rojas JD, Kelly KA, Wu G. Impaired nitric oxide production in coronary endothelial cells of the spontaneously diabetic BB rat is due to tetrahydrobiopterin deficiency. Biochem J 349: 353-356, 2000.
-
(2000)
Biochem J
, vol.349
, pp. 353-356
-
-
Meininger, C.J.1
Marinos, R.S.2
Hatakeyama, K.3
Martinez-Zaguilan, R.4
Rojas, J.D.5
Kelly, K.A.6
Wu, G.7
-
26
-
-
33750200993
-
Tetrahydrobiopterin and cardiovascular disease
-
Moens AL, Kass DA. Tetrahydrobiopterin and cardiovascular disease. Arterioscler Thromb Vasc Biol 26: 2439-2444, 2006.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 2439-2444
-
-
Moens, A.L.1
Kass, D.A.2
-
27
-
-
79960803194
-
Targeting endothelial and myocardial dysfunction with tetrahydrobiopterin
-
Moens AL, Kietadisorn R, Lin JY, Kass D. Targeting endothelial and myocardial dysfunction with tetrahydrobiopterin. J Mol Cell Cardiol 51: 559-563, 2011.
-
(2011)
J Mol Cell Cardiol
, vol.51
, pp. 559-563
-
-
Moens, A.L.1
Kietadisorn, R.2
Lin, J.Y.3
Kass, D.4
-
28
-
-
17744381754
-
Pulmonary hypertension in a GTP-cyclohydrolase 1-deficient mouse
-
Nandi M, Miller A, Stidwill R, Jacques TS, Lam AA, Haworth S, Heales S, Vallance P. Pulmonary hypertension in a GTP-cyclohydrolase 1-deficient mouse. Circulation 111: 2086-2090, 2005.
-
(2005)
Circulation
, vol.111
, pp. 2086-2090
-
-
Nandi, M.1
Miller, A.2
Stidwill, R.3
Jacques, T.S.4
Lam, A.A.5
Haworth, S.6
Heales, S.7
Vallance, P.8
-
29
-
-
0021891891
-
Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin
-
Nichol CA, Smith GK, Duch DS. Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin. Annu Rev Biochem 54: 729-764, 1985.
-
(1985)
Annu Rev Biochem
, vol.54
, pp. 729-764
-
-
Nichol, C.A.1
Smith, G.K.2
Duch, D.S.3
-
30
-
-
33846863589
-
Nitric oxide and peroxynitrite in health and disease
-
Pacher P, Beckman JS, Liaudet L. Nitric oxide and peroxynitrite in health and disease. Physiol Rev 87: 315-424, 2007.
-
(2007)
Physiol Rev
, vol.87
, pp. 315-424
-
-
Pacher, P.1
Beckman, J.S.2
Liaudet, L.3
-
31
-
-
0023912670
-
Vascular endothelial cells synthesize nitric oxide from L-arginine
-
Palmer RMJ, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 333: 664-666, 1988.
-
(1988)
Nature
, vol.333
, pp. 664-666
-
-
Palmer, R.M.J.1
Ashton, D.S.2
Moncada, S.3
-
32
-
-
0025750850
-
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells
-
Pollock JS, Förstermann U, Mitchell JA, Warner TD, Schmidt HH, Nakane M, Murad F. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc Natl Acad Sci USA 88: 10480-10484, 1991.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 10480-10484
-
-
Pollock, J.S.1
Förstermann, U.2
Mitchell, J.A.3
Warner, T.D.4
Schmidt, H.H.5
Nakane, M.6
Murad, F.7
-
33
-
-
0032416666
-
Crystal structure of constitutive endothelial nitric oxide synthase: A paradigm for pterin function involving a novel metal center
-
Raman CS, Li H, Martasek P, Kral V, Masters BS, Poulos TL. Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center. Cell 95: 939-950, 1998.
-
(1998)
Cell
, vol.95
, pp. 939-950
-
-
Raman, C.S.1
Li, H.2
Martasek, P.3
Kral, V.4
Masters, B.S.5
Poulos, T.L.6
-
34
-
-
0021063422
-
Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation
-
Rapoport RM, Draznin MB, Murad F. Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation. Nature 306: 174-176, 1983.
-
(1983)
Nature
, vol.306
, pp. 174-176
-
-
Rapoport, R.M.1
Draznin, M.B.2
Murad, F.3
-
35
-
-
0033512422
-
Abnormal biopterin metabolism is a major cause of impaired endothelium- dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta
-
Shinozaki K, Kashiwagi A, Nishio Y, Okamura T, Yoshida Y, Masada M, Toda N, Kikkawa R. Abnormal biopterin metabolism is a major cause of impaired endothelium- dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta. Diabetes 48: 2437-2445, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 2437-2445
-
-
Shinozaki, K.1
Kashiwagi, A.2
Nishio, Y.3
Okamura, T.4
Yoshida, Y.5
Masada, M.6
Toda, N.7
Kikkawa, R.8
-
36
-
-
0028805056
-
The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase
-
Stralin P, Karlsson K, Johansson BO, Marklund SL. The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase. Arterioscler Thromb Vasc Biol 15: 2032-2036, 1995.
-
(1995)
Arterioscler Thromb Vasc Biol
, vol.15
, pp. 2032-2036
-
-
Stralin, P.1
Karlsson, K.2
Johansson, B.O.3
Marklund, S.L.4
-
37
-
-
0031018510
-
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia
-
Stroes E, Kastelein J, Cosentino F, Erkelens W, Wever R, Koomans H, Lüscher T, Rabelink T. Tetrahydrobiopterin restores endothelial function in hypercholesterolemia. J Clin Invest 99: 41-46, 1997.
-
(1997)
J Clin Invest
, vol.99
, pp. 41-46
-
-
Stroes, E.1
Kastelein, J.2
Cosentino, F.3
Erkelens, W.4
Wever, R.5
Koomans, H.6
Lüscher, T.7
Rabelink, T.8
-
38
-
-
67649781721
-
Tetrahydrobiopterin recycling, a keydeterminant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells
-
Sugiyama T, Levy BD, Michel T. Tetrahydrobiopterin recycling, a keydeterminant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells. J Biol Chem 284: 12691-12700, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 12691-12700
-
-
Sugiyama, T.1
Levy, B.D.2
Michel, T.3
-
39
-
-
0037155131
-
Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway
-
Thomas SR, Chen K, Keaney JF Jr. Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway. J Biol Chem 277: 6017-6024, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 6017-6024
-
-
Thomas, S.R.1
Chen, K.2
Keaney Jr., J.F.3
-
40
-
-
0032482975
-
Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors
-
Vasquez-Vivar J, Kalyanaraman B, Martasek P, Hogg N, Masters BS, Karoui H, Tordo P, Pritchard KA Jr. Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. Proc Natl Acad Sci USA 95: 9220-9225, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9220-9225
-
-
Vasquez-Vivar, J.1
Kalyanaraman, B.2
Martasek, P.3
Hogg, N.4
Masters, B.S.5
Karoui, H.6
Tordo, P.7
Pritchard Jr., K.A.8
-
41
-
-
0037086565
-
The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: An EPR spin trapping study
-
Vasquez-Vivar J, Martasek P, Whitsett J, Joseph J, Kalyanaraman B. The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study. Biochem J 362: 733-739, 2002.
-
(2002)
Biochem J
, vol.362
, pp. 733-739
-
-
Vasquez-Vivar, J.1
Martasek, P.2
Whitsett, J.3
Joseph, J.4
Kalyanaraman, B.5
-
42
-
-
23044446257
-
Tetrahydrobiopterin deficiency exaggerates intimal hyperplasia after vascular injury
-
Wang CH, Li SH, Weisel RD, Fedak PW, Hung A, Li RK, Rao V, Hyland K, Cherng WJ, Errett L, Leclerc Y, Bonneau D, Latter DA, Verma S. Tetrahydrobiopterin deficiency exaggerates intimal hyperplasia after vascular injury. Am J Physiol Regul Integr Comp Physiol 289: R299-R304, 2005.
-
(2005)
Am J Physiol Regul Integr Comp Physiol
, vol.289
-
-
Wang, C.H.1
Li, S.H.2
Weisel, R.D.3
Fedak, P.W.4
Hung, A.5
Li, R.K.6
Rao, V.7
Hyland, K.8
Cherng, W.J.9
Errett, L.10
Leclerc, Y.11
Bonneau, D.12
Latter, D.A.13
Verma, S.14
-
43
-
-
48449093231
-
AT1-receptor blockade by telmisartan upregulates GTP-cyclohydrolase I and protects eNOS in diabetic rats
-
Wenzel P, Schulz E, Oelze M, Muller J, Schuhmacher S, Alhamdani MS, Debrezion J, Hortmann M, Reifenberg K, Fleming I, Munzel T, Daiber A. AT1-receptor blockade by telmisartan upregulates GTP-cyclohydrolase I and protects eNOS in diabetic rats. Free Radic Biol Med 45: 619-626, 2008.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 619-626
-
-
Wenzel, P.1
Schulz, E.2
Oelze, M.3
Muller, J.4
Schuhmacher, S.5
Alhamdani, M.S.6
Debrezion, J.7
Hortmann, M.8
Reifenberg, K.9
Fleming, I.10
Munzel, T.11
Daiber, A.12
-
44
-
-
0031577442
-
Tetrahydrobiopterin regulates superoxide and nitric oxide generation by recombinant endothelial nitric oxide synthase
-
Wever RM, van Dam T, van Rijn HJ, de Groot F, Rabelink TJ. Tetrahydrobiopterin regulates superoxide and nitric oxide generation by recombinant endothelial nitric oxide synthase. Biochem Biophys Res Commun 237: 340-344, 1997.
-
(1997)
Biochem Biophys Res Commun
, vol.237
, pp. 340-344
-
-
Wever, R.M.1
van Dam, T.2
van Rijn, H.J.3
de Groot, F.4
Rabelink, T.J.5
-
45
-
-
0032475865
-
Superoxide generation from endothelial nitric-oxide synthase. A Ca2/calmodulin-dependent and tetrahydrobiopterin regulatory process
-
Xia Y, Tsai AL, Berka V, Zweier JL. Superoxide generation from endothelial nitric-oxide synthase. A Ca2/calmodulin-dependent and tetrahydrobiopterin regulatory process. J Biol Chem 273: 25804-25808, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 25804-25808
-
-
Xia, Y.1
Tsai, A.L.2
Berka, V.3
Zweier, J.L.4
-
46
-
-
34548134851
-
Proteasomedependent degradation of guanosine 5=-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus
-
Xu J, Wu Y, Song P, Zhang M, Wang S, Zou MH. Proteasomedependent degradation of guanosine 5=-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus. Circulation 116: 944-953, 2007.
-
(2007)
Circulation
, vol.116
, pp. 944-953
-
-
Xu, J.1
Wu, Y.2
Song, P.3
Zhang, M.4
Wang, S.5
Zou, M.H.6
-
47
-
-
0033859852
-
Mechanisms of reduced nitric oxide/ cGMP-mediated vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase
-
Yamashita T, Kawashima S, Ohashi Y, Ozaki M, Rikitake Y, Inoue N, Hirata K, Akita H, Yokoyama M. Mechanisms of reduced nitric oxide/ cGMP-mediated vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase. Hypertension 36: 97-102, 2000.
-
(2000)
Hypertension
, vol.36
, pp. 97-102
-
-
Yamashita, T.1
Kawashima, S.2
Ohashi, Y.3
Ozaki, M.4
Rikitake, Y.5
Inoue, N.6
Hirata, K.7
Akita, H.8
Yokoyama, M.9
-
48
-
-
34848928700
-
Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk
-
Zhang L, Rao F, Zhang K, Khandrika S, Das M, Vaingankar SM, Bao X, Rana BK, Smith DW, Wessel J, Salem RM, Rodriguez-Flores JL, Mahata SK, Schork NJ, Ziegler MG, O'Connor DT. Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk. J Clin Invest 117: 2658-2671, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 2658-2671
-
-
Zhang, L.1
Rao, F.2
Zhang, K.3
Khandrika, S.4
Das, M.5
Vaingankar, S.M.6
Bao, X.7
Rana, B.K.8
Smith, D.W.9
Wessel, J.10
Salem, R.M.11
Rodriguez-Flores, J.L.12
Mahata, S.K.13
Schork, N.J.14
Ziegler, M.G.15
O'Connor, D.T.16
-
49
-
-
33644628456
-
Mechanistic similarities between oxidation of hydroethidine by Fremy's salt and superoxide: Stopped-flow optical and EPR studies
-
Zielonka J, Zhao H, Xu Y, Kalyanaraman B. Mechanistic similarities between oxidation of hydroethidine by Fremy's salt and superoxide: stopped-flow optical and EPR studies. Free Radic Biol Med 39: 853-863, 2005.
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 853-863
-
-
Zielonka, J.1
Zhao, H.2
Xu, Y.3
Kalyanaraman, B.4
-
50
-
-
0037031892
-
Modulation by peroxynitrite of Akt- and AMP-activated kinase-dependent Ser1179 phosphorylation of endothelial nitric oxide synthase
-
Zou MH, Hou XY, Shi CM, Nagata D, Walsh K, Cohen RA. Modulation by peroxynitrite of Akt- and AMP-activated kinase-dependent Ser1179 phosphorylation of endothelial nitric oxide synthase. J Biol Chem 277: 32552-32557, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 32552-32557
-
-
Zou, M.H.1
Hou, X.Y.2
Shi, C.M.3
Nagata, D.4
Walsh, K.5
Cohen, R.A.6
|