Enhanced mitochondrial superoxide in hyperglycemic endothelial cells: Direct measurements and formation of hydrogen peroxide and peroxynitrite

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 293, Issue 6, 2007, Pages

  Quijano, Celia ^a   Castro, Laura ^a   Peluffo, Gonzalo ^a   Valez, Valeria ^a   Radi, Rafael ^a,b  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

Author keywords

Aconitase; Hyperglycemia; Mitochondria; MitoSOX

Indexed keywords

ACONITATE HYDRATASE; AMINOTRIAZOLE; GLUTATHIONE; HYDROETHIDINE; HYDROGEN PEROXIDE; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL PROTEIN; MYXOTHIAZOL; NITRATE; NITRITE; OXYGEN; PEROXYNITRITE; SUPEROXIDE; TYROSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DAMAGE; CITRIC ACID CYCLE; CONTROLLED STUDY; DATA ANALYSIS; ENDOTHELIUM CELL; ENZYME ACTIVITY; GLUCOSE INTAKE; HYPERGLYCEMIA; IMAGE PROCESSING; IMMUNOCHEMISTRY; MEASUREMENT; MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; STEADY STATE; SWINE;

ACONITATE HYDRATASE; ANIMALS; CATALASE; CATTLE; CELLS, CULTURED; CITRIC ACID CYCLE; ENDOTHELIAL CELLS; ENZYME INHIBITORS; FLUORESCEINS; FLUORESCENT DYES; GLUCOSE; HYDROGEN PEROXIDE; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; NITRIC OXIDE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PEROXYNITROUS ACID; PHENANTHRIDINES; SUPEROXIDES; TIME FACTORS; TRIAZOLES; TYROSINE;

EID: 36849023528     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00761.2007     Document Type: Article

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