Effects of Rhein Lysinate on H 2O 2-induced cellular senescence of human umbilical vascular endothelial cells

Acta Pharmacologica Sinica

Volumn 32, Issue 10, 2011, Pages 1246-1252

  Lin, Ya Jun ^a   Zhen, Yong Zhan ^b   Wei, Jie ^a   Liu, Bo ^a   Yu, Zong Yuan ^a   Hu, Gang ^a  

^a BEIJING HOSPITAL   (China)

^b HEBEI UNITED UNIVERSITY   (China)

Author keywords

cell cycle; H 2O 2; human umbilical vascular endothelial cells (HUVECs); Rhein lysinate; RNA interference; senescence; Sirt1

Indexed keywords

BETA GALACTOSIDASE; HYDROGEN PEROXIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P16; PROTEIN P21; PROTEIN P53; RHEIN; RHEIN LYSINATE; SIRTUIN 1; UNCLASSIFIED DRUG;

ACETYLATION; APOPTOSIS; ARTICLE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL SENESCENCE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN UMBILICAL VASCULAR ENDOTHELIAL CELL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; SENESCENCE; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ANTHRAQUINONES; CELL AGING; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; ENDOTHELIAL CELLS; ENZYME INHIBITORS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; RHEUM; SIRTUIN 1; TRANSCRIPTION, GENETIC;

EID: 80053912911     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.101     Document Type: Article

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