Targeted detoxification of selected reactive oxygen species in the vascular endothelium

Journal of Pharmacology and Experimental Therapeutics

Volumn 331, Issue 2, 2009, Pages 404-411

  Shuvaev, Vladimir V ^a   Christofidou Solomidou, Melpo ^a   Bhora, Faiz ^a   Laude, Karine ^b   Cai, Hua ^c   Dikalov, Sergei ^b   Arguiri, Evguenia ^a   Solomides, Charalambos C ^d   Albelda, Steven M ^a   Harrison, David G ^b   Muzykantov, Vladimir R ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; ANTIBODY; CATALASE; CD31 ANTIBODY; CD31 ANTIGEN; GLUCOSE OXIDASE; HYDROGEN PEROXIDE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; TETRAHYDROBIOPTERIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL OXYGEN TENSION; ARTICLE; CELL STRESS; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DETOXIFICATION; DRUG CONJUGATION; ENDOTHELIUM CELL; HYPERTENSION; ISCHEMIA; KNOCKOUT MOUSE; LUNG BLOOD VESSEL; LUNG EDEMA; LUNG INJURY; LUNG PERFUSION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REPERFUSION; TISSUE INJURY; VASCULAR DISEASE; VASCULAR ENDOTHELIUM; VASODILATATION; WILD TYPE;

ANGIOTENSIN II; ANIMALS; ANTIBODIES; ANTIGENS, CD31; ANTIOXIDANTS; BIOPTERIN; BRONCHOALVEOLAR LAVAGE FLUID; CATALASE; CROSS-LINKING REAGENTS; ENDOTHELIUM, VASCULAR; GLUCOSE OXIDASE; HYDROGEN PEROXIDE; LUNG DISEASES; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PULMONARY CIRCULATION; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; SUPEROXIDE DISMUTASE; SUPEROXIDES;

EID: 70350455927     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.156877     Document Type: Article

References (40)

1. Andreadis AA, Hazen SL, Comhair SA, and Erzurum SC (2003) Oxidative and nitrosative events in asthma. Free Radic Biol Med 35:213-225.
2. Bonaventura J and Gow A (2004) NO and superoxide: opposite ends of the seesaw in cardiac contractility. Proc Natl Acad Sci U S A 101:16403-16404. (Pubitemid 39557725)
3. Cai H (2005) Hydrogen peroxide regulation of endothelial function: origins, mechanisms, and consequences. Cardiovasc Res 68:26-36. (Pubitemid 41253553)
4. Cai H, Griendling KK, and Harrison DG (2003) The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol Sci 24:471-478. (Pubitemid 37088172)
5. Christofidou-Solomidou M, Scherpereel A, Wiewrodt R, Ng K, Sweitzer T, Arguiri E, Shuvaev V, Solomides CC, Albelda SM, and Muzykantov VR (2003) PECAM-directed delivery of catalase to endothelium protects against pulmonary vascular oxidative stress. Am J Physiol Lung Cell Mol Physiol 285:L283-L292. (Pubitemid 36909443)
6. Dikalov S, Griendling KK, and Harrison DG (2007) Measurement of reactive oxygen species in cardiovascular studies. Hypertension 49:717-727. (Pubitemid 351688335)
7. Fukushima T and Nixon JC (1980) Analysis of reduced forms of biopterin in biological tissues and fluids. Anal Biochem 102:176-188. (Pubitemid 10099498)
8. Gao B, Flores SC, Leff JA, Bose SK, and McCord JM (2003) Synthesis and anti-inflammatory activity of a chimeric recombinant superoxide dismutase: SOD2/3. Am J Physiol Lung Cell Mol Physiol 284:L917-L925. (Pubitemid 36687126)
9. Goswami SK, Maulik N, and Das DK (2007) Ischemia-reperfusion and cardioprotection: a delicate balance between reactive oxygen species generation and redox homeostasis. Ann Med 39:275-289. (Pubitemid 46897661)
10. Guo AM, Arbab AS, Falck JR, Chen P, Edwards PA, Roman RJ, and Scicli AG (2007) Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation. J Pharmacol Exp Ther 321:18-27. (Pubitemid 46456964)
11. Guo RF and Ward PA (2007) Role of oxidants in lung injury during sepsis. Antioxid Redox Signal 9:1991-2002. (Pubitemid 47622351)
12. Houston M, Estevez A, Chumley P, Aslan M, Marklund S, Parks DA, and Freeman BA (1999) Binding of xanthine oxidase to vascular endothelium. Kinetic characterization and oxidative impairment of nitric oxide-dependent signaling. J Biol Chem 274:4985-4994. (Pubitemid 129501516)
13. Kennedy TP, Rao NV, Hopkins C, Pennington L, Tolley E, and Hoidal JR (1989) Role of reactive oxygen species in reperfusion injury of the rabbit lung. J Clin Invest 83:1326-1335. (Pubitemid 19113049)
14. Kinniry P, Amrani Y, Vachani A, Solomides CC, Arguiri E, Workman A, Carter J, and Christofidou-Solomidou M (2006) Dietary flaxseed supplementation ameliorates inflammation and oxidative tissue damage in experimental models of acute lung injury in mice. J Nutr 136:1545-1551. (Pubitemid 43765360)
15. Kozower BD, Christofidou-Solomidou M, Sweitzer TD, Muro S, Buerk DG, Solomides CC, Albelda SM, Patterson GA, and Muzykantov VR (2003) Immunotargeting of catalase to the pulmonary endothelium alleviates oxidative stress and reduces acute lung transplantation injury. Nat Biotechnol 21:392-398. (Pubitemid 36397659)
16. Krause KH and Bedard K (2008) NOX enzymes in immuno-inflammatory pathologies. Semin Immunopathol 30:193-194.
17. Kuzkaya N, Weissmann N, Harrison DG, and Dikalov S (2003) Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase. J Biol Chem 278:22546-22554. (Pubitemid 36830310)
18. Landmesser U, Dikalov S, Price SR, McCann L, Fukai T, Holland SM, Mitch WE, and Harrison DG (2003) Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest 111:1201-1209. (Pubitemid 36519937)
19. Lee JC, Bhora F, Sun J, Cheng G, Arguiri E, Solomides CC, Chatterjee S, and Christofidou-Solomidou M (2008) Dietary flaxseed enhances antioxidant defenses and is protective in a mouse model of lung ischemia-reperfusion injury. Am J Physiol Lung Cell Mol Physiol 294:L255-L265. (Pubitemid 351253362)
20. Li S, Tan Y, Viroonchatapan E, Pitt BR, and Huang L (2000) Targeted gene delivery to pulmonary endothelium by anti-PECAM antibody. Am J Physiol Lung Cell Mol Physiol 278:L504-L511. (Pubitemid 30152507)
21. Loomis ED, Sullivan JC, Osmond DA, Pollock DM, and Pollock JS (2005) Endothelin mediates superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta. J Pharmacol Exp Ther 315:1058-1064.
22. Matthay MA, Zimmerman GA, Esmon C, Bhattacharya J, Coller B, Doerschuk CM, Floros J, Gimbrone MA Jr, Hoffman E, Hubmayr RD, et al. (2003) Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med 167:1027-1035. (Pubitemid 36408170)
23. McCord JM (2002) Superoxide dismutase in aging and disease: an overview. Methods Enzymol 349:331-341. (Pubitemid 34229520)
24. Muzykantov VR (2001) Targeting of superoxide dismutase and catalase to vascular endothelium. J Control Release 71:1-21. (Pubitemid 32195437)
25. Muzykantov VR (2005) Biomedical aspects of targeted delivery of drugs to pulmonary endothelium. Expert Opin Drug Deliv 2:909-926.
26. Muzykantov VR, Atochina EN, Ischiropoulos H, Danilov SM, and Fisher AB (1996) Immunotargeting of antioxidant enzyme to the pulmonary endothelium. Proc Natl Acad Sci U S A 93:5213-5218. (Pubitemid 26159428)
27. Muzykantov VR, Christofidou-Solomidou M, Balyasnikova I, Harshaw DW, Schultz L, Fisher AB, and Albelda SM (1999) Streptavidin facilitates internalization and pulmonary targeting of an antiendothelial cell antibody (platelet-endothelial cell adhesion molecule 1): a strategy for vascular immunotargeting of drugs. Proc Natl Acad Sci U S A 96:2379-2384. (Pubitemid 29117923)
28. Newman PJ (1997) The biology of PECAM-1. J Clin Invest 99:3-8.
29. Nowak K, Weih S, Metzger R, Albrecht RF 2nd, Post S, Hohenberger P, Gebhard MM, and Danilov SM (2007) Immunotargeting of catalase to lung endothelium via anti-ACE antibodies attenuates ischemia-reperfusion injury of the lung in vivo. Am J Physiol Lung Cell Mol Physiol 293:L162-L169.
30. Ovechkin AV, Lominadze D, Sedoris KC, Robinson TW, Tyagi SC, and Roberts AM (2007) Lung ischemia-reperfusion injury: implications of oxidative stress and platelet-arteriolar wall interactions. Arch Physiol Biochem 113:1-12. (Pubitemid 46825684)
31. Perkowski S, Scherpereel A, Murciano JC, Arguiri E, Solomides CC, Albelda SM, Muzykantov V, and Christofidou-Solomidou M (2006) Dissociation between alveolar transmigration of neutrophils and lung injury in hyperoxia. Am J Physiol Lung Cell Mol Physiol 291:L1050-L1058. (Pubitemid 44772067)
32. Porkert M, Sher S, Reddy U, Cheema F, Niessner C, Kolm P, Jones DP, Hooper C, Taylor WR, Harrison D, et al. (2008) Tetrahydrobiopterin: a novel antihypertensive therapy. J Hum Hypertens 22:401-407.
33. Saitoh S, Kiyooka T, Rocic P, Rogers PA, Zhang C, Swafford A, Dick GM, Viswanathan C, Park Y, and Chilian WM (2007) Redox-dependent coronary metabolic dilation. Am J Physiol Heart Circ Physiol 293:H3720-H3725.
34. Shuvaev VV, Christofidou-Solomidou M, Scherpereel A, Simone E, Arguiri E, Tliba S, Pick J, Kennel S, Albelda SM, and Muzykantov VR (2007a) Factors modulating the delivery and effect of enzymatic cargo conjugated with antibodies targeted to the pulmonary endothelium. J Control Release 118:235-244. (Pubitemid 46329740)
35. Shuvaev VV, Tliba S, Nakada M, Albelda SM, and Muzykantov VR (2007b) Platelet-endothelial cell adhesion molecule-1-directed endothelial targeting of superoxide dismutase alleviates oxidative stress caused by either extracellular or intracellular superoxide. J Pharmacol Exp Ther 323:450-457. (Pubitemid 350005112)
36. Sweitzer TD, Thomas AP, Wiewrodt R, Nakada MT, Branco F, and Muzykantov VR (2003) PECAM-directed immunotargeting of catalase: specific, rapid and transient protection against hydrogen peroxide. Free Radic Biol Med 34:1035-1046. (Pubitemid 36398563)
37. Terada LS, Guidot DM, Leff JA, Willingham IR, Hanley ME, Piermattei D, and Repine JE (1992) Hypoxia injures endothelial cells by increasing endogenous xanthine oxidase activity. Proc Natl Acad Sci U S A 89:3362-3366.
38. Widder JD, Guzik TJ, Mueller CF, Clempus RE, Schmidt HH, Dikalov SI, Griendling KK, Jones DP, and Harrison DG (2007) Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II. Arterioscler Thromb Vasc Biol 27:762-768. (Pubitemid 46606704)
39. Yang H, Roberts LJ, Shi MJ, Zhou LC, Ballard BR, Richardson A, and Guo ZM (2004) Retardation of atherosclerosis by overexpression of catalase or both Cu/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein E. Circ Res 95:1075-1081. (Pubitemid 39557894)
40. Zou MH (2007) Peroxynitrite and protein tyrosine nitration of prostacyclin synthase. Prostaglandins Other Lipid Mediat 82:119-127. (Pubitemid 44911071)