-
2
-
-
80051730491
-
Fluids and barriers of the CNS: A historical viewpoint
-
Liddelow SA. Fluids and barriers of the CNS: a historical viewpoint. Fluids Barriers CNS 2011; 8: 2.
-
(2011)
Fluids Barriers CNS
, vol.8
, pp. 2
-
-
Liddelow, S.A.1
-
3
-
-
31444447324
-
Brain endothelial hemostasis regulation by pericytes
-
Kim JA, Tran ND, Li Z, Yang F, Zhou W, Fisher MJ. Brain endothelial hemostasis regulation by pericytes. J Cereb Blood Flow Metab 2006; 26: 209-17.
-
(2006)
J Cereb Blood Flow Metab
, vol.26
, pp. 209-217
-
-
Kim, J.A.1
Tran, N.D.2
Li, Z.3
Yang, F.4
Zhou, W.5
Fisher, M.J.6
-
4
-
-
0027931494
-
Effect of peptidases at the blood brain barrier on the permeability of enkephalin
-
Brownson EA, Abbruscato TJ, Gillespie TJ, Hruby VJ, Davis TP. Effect of peptidases at the blood brain barrier on the permeability of enkephalin. J Pharmacol Exp Ther 1994; 270: 675-80.
-
(1994)
J Pharmacol Exp Ther
, vol.270
, pp. 675-680
-
-
Brownson, E.A.1
Abbruscato, T.J.2
Gillespie, T.J.3
Hruby, V.J.4
Davis, T.P.5
-
5
-
-
12344262373
-
Blood-brain barrier active efflux transporters: ATP-binding cassette gene family
-
Loscher W, Potschka H. Blood-brain barrier active efflux transporters: ATP-binding cassette gene family. NeuroRx 2005; 2: 86-98.
-
(2005)
NeuroRx
, vol.2
, pp. 86-98
-
-
Loscher, W.1
Potschka, H.2
-
6
-
-
0023116789
-
Chemotherapy administered in conjunction with osmotic blood-brain barrier modification in patients with brain metastases
-
Neuwelt EA, Dahlborg SA. Chemotherapy administered in conjunction with osmotic blood-brain barrier modification in patients with brain metastases. J Neurooncol 1987; 4: 195-207.
-
(1987)
J Neurooncol
, vol.4
, pp. 195-207
-
-
Neuwelt, E.A.1
Dahlborg, S.A.2
-
7
-
-
67349099863
-
Intranasal administration of IGF-1 attenuates hypoxic-ischemic brain injury in neonatal rats
-
Lin S, Fan LW, Rhodes PG, Cai Z. Intranasal administration of IGF-1 attenuates hypoxic-ischemic brain injury in neonatal rats. Exp Neurol 2009; 217: 361-70.
-
(2009)
Exp Neurol
, vol.217
, pp. 361-370
-
-
Lin, S.1
Fan, L.W.2
Rhodes, P.G.3
Cai, Z.4
-
8
-
-
69949156876
-
Inhibition of human P-glycoprotein transport and substrate binding using a galantamine dimer
-
Namanja HA, Emmert D, Pires MM, Hrycyna CA, Chmielewski J. Inhibition of human P-glycoprotein transport and substrate binding using a galantamine dimer. Biochem Biophys Res Commun 2009; 388: 672-6.
-
(2009)
Biochem Biophys Res Commun
, vol.388
, pp. 672-676
-
-
Namanja, H.A.1
Emmert, D.2
Pires, M.M.3
Hrycyna, C.A.4
Chmielewski, J.5
-
9
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse
-
Schwarze SR, Ho A, Vocero-Akbani A, Dowdy SF. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 1999; 285: 1569-72.
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
10
-
-
0028558577
-
Intravenous administration of a transferrin receptor antibody-nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington disease
-
Kordower JH, Charles V, Bayer R, et al. Intravenous administration of a transferrin receptor antibody-nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington disease. Proc Natl Acad Sci USA 1994; 91: 9077-80.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9077-9080
-
-
Kordower, J.H.1
Charles, V.2
Bayer, R.3
-
11
-
-
0034691050
-
Noninvasive gene targeting to the brain
-
Shi N, Pardridge WM. Noninvasive gene targeting to the brain. Proc Natl Acad Sci USA 2000; 97: 7567-72.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 7567-7572
-
-
Shi, N.1
Pardridge, W.M.2
-
12
-
-
33846326883
-
Nanotechnology approaches for drug and small molecule delivery across the blood brain barrier
-
Silva GA. Nanotechnology approaches for drug and small molecule delivery across the blood brain barrier. Surg Neurol 2007; 67: 113-6.
-
(2007)
Surg Neurol
, vol.67
, pp. 113-116
-
-
Silva, G.A.1
-
13
-
-
0024262589
-
Cellular uptake of the tat protein from human immunodeficiency virus
-
Frankel AD, Pabo CO. Cellular uptake of the tat protein from human immunodeficiency virus. Cell 1988; 55: 1189-93.
-
(1988)
Cell
, vol.55
, pp. 1189-1193
-
-
Frankel, A.D.1
Pabo, C.O.2
-
16
-
-
79956015439
-
Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo
-
Andaloussi SE, Lehto T, Mager I, et al. Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo. Nucleic Acids Res; 39: 3972-87.
-
Nucleic Acids Res
, vol.39
, pp. 3972-3987
-
-
Andaloussi, S.E.1
Lehto, T.2
Mager, I.3
-
17
-
-
0030955260
-
Conformations of primary amphipathic carrier peptides in membrane mimicking environments
-
Chaloin L, Vidal P, Heitz A, et al. Conformations of primary amphipathic carrier peptides in membrane mimicking environments. Biochemistry 1997; 36: 11179-87.
-
(1997)
Biochemistry
, vol.36
, pp. 11179-11187
-
-
Chaloin, L.1
Vidal, P.2
Heitz, A.3
-
18
-
-
0034700141
-
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
-
Wender PA, Mitchell DJ, Pattabiraman K, Pelkey ET, Steinman L, Rothbard JB. The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc Natl Acad Sci USA 2000; 97: 13003-8.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13003-13008
-
-
Wender, P.A.1
Mitchell, D.J.2
Pattabiraman, K.3
Pelkey, E.T.4
Steinman, L.5
Rothbard, J.B.6
-
19
-
-
53549090429
-
Enhanced delivery efficiency of recombinant adenovirus into tumor and mesenchymal stem cells by a novel PTD
-
Youn JI, Park SH, Jin HT, et al. Enhanced delivery efficiency of recombinant adenovirus into tumor and mesenchymal stem cells by a novel PTD. Cancer Gene Ther 2008; 15: 703-12.
-
(2008)
Cancer Gene Ther
, vol.15
, pp. 703-712
-
-
Youn, J.I.1
Park, S.H.2
Jin, H.T.3
-
20
-
-
0033794501
-
Polyarginine enters cells more efficiently than other polycationic homopolymers
-
Mitchell DJ, Kim DT, Steinman L, Fathman CG, Rothbard JB. Polyarginine enters cells more efficiently than other polycationic homopolymers. J Pept Res 2000; 56: 318-25.
-
(2000)
J Pept Res
, vol.56
, pp. 318-325
-
-
Mitchell, D.J.1
Kim, D.T.2
Steinman, L.3
Fathman, C.G.4
Rothbard, J.B.5
-
21
-
-
19444382074
-
The engineering of membranepermeable peptides
-
Carrigan CN, Imperiali B. The engineering of membranepermeable peptides. Anal Biochem 2005; 341: 290-8.
-
(2005)
Anal Biochem
, vol.341
, pp. 290-298
-
-
Carrigan, C.N.1
Imperiali, B.2
-
22
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
-
Vives E, Brodin P, Lebleu B. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem 1997; 272: 16010-7.
-
(1997)
J Biol Chem
, vol.272
, pp. 16010-16017
-
-
Vives, E.1
Brodin, P.2
Lebleu, B.3
-
23
-
-
0028239908
-
The third helix of the Antennapedia homeodomain translocates through biological membranes
-
Derossi D, Joliot AH, Chassaing G, Prochiantz A. The third helix of the Antennapedia homeodomain translocates through biological membranes. J Biol Chem 1994; 269: 10444-50.
-
(1994)
J Biol Chem
, vol.269
, pp. 10444-10450
-
-
Derossi, D.1
Joliot, A.H.2
Chassaing, G.3
Prochiantz, A.4
-
24
-
-
0031471203
-
Intercellular trafficking and protein delivery by a herpesvirus structural protein
-
Elliott G, O'Hare P. Intercellular trafficking and protein delivery by a herpesvirus structural protein. Cell 1997; 88: 223-33.
-
(1997)
Cell
, vol.88
, pp. 223-233
-
-
Elliott, G.1
O'Hare, P.2
-
25
-
-
0034126420
-
New advances in the transport of doxorubicin through the blood-brain barrier by a peptide vector-mediated strategy
-
Rousselle C, Clair P, Lefauconnier JM, Kaczorek M, Scherrmann JM, Temsamani J. New advances in the transport of doxorubicin through the blood-brain barrier by a peptide vector-mediated strategy. Mol Pharmacol 2000; 57: 679-86.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 679-686
-
-
Rousselle, C.1
Clair, P.2
Lefauconnier, J.M.3
Kaczorek, M.4
Scherrmann, J.M.5
Temsamani, J.6
-
26
-
-
0035478616
-
VE-cadherinderived cell-penetrating peptide, pVEC, with carrier functions
-
Elmquist A, Lindgren M, Bartfai T, Langel U. VE-cadherinderived cell-penetrating peptide, pVEC, with carrier functions. Exp Cell Res 2001; 269: 237-44.
-
(2001)
Exp Cell Res
, vol.269
, pp. 237-244
-
-
Elmquist, A.1
Lindgren, M.2
Bartfai, T.3
Langel, U.4
-
27
-
-
11844302810
-
Decoding the entry of two novel cell-penetrating peptides in HeLa cells: Lipid raft-mediated endocytosis and endosomal escape
-
Foerg C, Ziegler U, Fernandez-Carneado J, et al. Decoding the entry of two novel cell-penetrating peptides in HeLa cells: lipid raft-mediated endocytosis and endosomal escape. Biochemistry 2005; 44: 72-81.
-
(2005)
Biochemistry
, vol.44
, pp. 72-81
-
-
Foerg, C.1
Ziegler, U.2
Fernandez-Carneado, J.3
-
28
-
-
50249171156
-
Detailed analysis concerning the biodistribution and metabolism of human calcitonin-derived cell-penetrating peptides
-
Neundorf I, Rennert R, Franke J, Kozle I, Bergmann R. Detailed analysis concerning the biodistribution and metabolism of human calcitonin-derived cell-penetrating peptides. Bioconjug Chem 2008; 19: 1596-603.
-
(2008)
Bioconjug Chem
, vol.19
, pp. 1596-1603
-
-
Neundorf, I.1
Rennert, R.2
Franke, J.3
Kozle, I.4
Bergmann, R.5
-
29
-
-
33750040895
-
Characterization of a novel cell penetrating peptide derived from Bag-1 protein
-
Niarchos DK, Perez SA, Papamichail M. Characterization of a novel cell penetrating peptide derived from Bag-1 protein. Peptides 2006; 27: 2661-9.
-
(2006)
Peptides
, vol.27
, pp. 2661-2669
-
-
Niarchos, D.K.1
Perez, S.A.2
Papamichail, M.3
-
30
-
-
73649137166
-
A cell-penetrating peptide derived from human lactoferrin with conformationdependent uptake efficiency
-
Duchardt F, Ruttekolk IR, Verdurmen WP, et al. A cell-penetrating peptide derived from human lactoferrin with conformationdependent uptake efficiency. J Biol Chem 2009; 284: 36099-108.
-
(2009)
J Biol Chem
, vol.284
, pp. 36099-36108
-
-
Duchardt, F.1
Ruttekolk, I.R.2
Verdurmen, W.P.3
-
31
-
-
56749185948
-
A novel cellpenetrating peptide sequence derived by structural minimization of a snake toxin exhibits preferential nucleolar localization
-
Radis-Baptista G, de la Torre BG, Andreu D. A novel cellpenetrating peptide sequence derived by structural minimization of a snake toxin exhibits preferential nucleolar localization. J Med Chem 2008; 51: 7041-4.
-
(2008)
J Med Chem
, vol.51
, pp. 7041-7044
-
-
Radis-Baptista, G.1
de la Torre, B.G.2
Andreu, D.3
-
32
-
-
79952809889
-
CyLoP-1: A novel cysteinerich cell-penetrating peptide for cytosolic delivery of cargoes
-
Jha D, Mishra R, Gottschalk S, et al. CyLoP-1: a novel cysteinerich cell-penetrating peptide for cytosolic delivery of cargoes. Bioconjug Chem 2011; 22: 319-28.
-
(2011)
Bioconjug Chem
, vol.22
, pp. 319-328
-
-
Jha, D.1
Mishra, R.2
Gottschalk, S.3
-
33
-
-
82255175122
-
A peptide derived from herpes simplex virus type 1 glycoprotein H: Membrane translocation and applications to the delivery of quantum dots
-
Falanga A, Vitiello MT, Cantisani M, et al. A peptide derived from herpes simplex virus type 1 glycoprotein H: membrane translocation and applications to the delivery of quantum dots. Nanomedicine 2011; 7: 925-34.
-
(2011)
Nanomedicine
, vol.7
, pp. 925-934
-
-
Falanga, A.1
Vitiello, M.T.2
Cantisani, M.3
-
34
-
-
3242798141
-
Enhancement of intracellular concentration and biological activity of PNA after conjugation with a cell-penetrating synthetic model peptide
-
Oehlke J, Wallukat G, Wolf Y, et al. Enhancement of intracellular concentration and biological activity of PNA after conjugation with a cell-penetrating synthetic model peptide. Eur J Biochem 2004; 271: 3043-9.
-
(2004)
Eur J Biochem
, vol.271
, pp. 3043-3049
-
-
Oehlke, J.1
Wallukat, G.2
Wolf, Y.3
-
35
-
-
33644861571
-
Mechanism of uptake of C105Y, a novel cellpenetrating peptide
-
Rhee M, Davis P. Mechanism of uptake of C105Y, a novel cellpenetrating peptide. J Biol Chem 2006; 281: 1233-40.
-
(2006)
J Biol Chem
, vol.281
, pp. 1233-1240
-
-
Rhee, M.1
Davis, P.2
-
36
-
-
34548771163
-
A novel cellpenetrating peptide, M918, for efficient delivery of proteins and peptide nucleic acids
-
El-Andaloussi S, Johansson HJ, Holm T, Langel U. A novel cellpenetrating peptide, M918, for efficient delivery of proteins and peptide nucleic acids. Mol Ther 2007; 15: 1820-6.
-
(2007)
Mol Ther
, vol.15
, pp. 1820-1826
-
-
El-Andaloussi, S.1
Johansson, H.J.2
Holm, T.3
Langel, U.4
-
37
-
-
63349084034
-
Identification and characterization of a novel cell-penetrating peptide
-
Sheng J, Oyler G, Zhou B, Janda K, Shoemaker CB. Identification and characterization of a novel cell-penetrating peptide. Biochem Biophys Res Commun 2009; 382: 236-40.
-
(2009)
Biochem Biophys Res Commun
, vol.382
, pp. 236-240
-
-
Sheng, J.1
Oyler, G.2
Zhou, B.3
Janda, K.4
Shoemaker, C.B.5
-
38
-
-
58149217884
-
A new potent secondary amphipathic cell-penetrating peptide for siRNA delivery into mammalian cells
-
Crombez L, Aldrian-Herrada G, Konate K, et al. A new potent secondary amphipathic cell-penetrating peptide for siRNA delivery into mammalian cells. Mol Ther 2009; 17: 95-103.
-
(2009)
Mol Ther
, vol.17
, pp. 95-103
-
-
Crombez, L.1
Aldrian-Herrada, G.2
Konate, K.3
-
39
-
-
0030804766
-
A new peptide vector for efficient delivery of oligonucleotides into mammalian cells
-
Morris MC, Vidal P, Chaloin L, Heitz F, Divita G. A new peptide vector for efficient delivery of oligonucleotides into mammalian cells. Nucleic Acids Res 1997; 25: 2730-6.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2730-2736
-
-
Morris, M.C.1
Vidal, P.2
Chaloin, L.3
Heitz, F.4
Divita, G.5
-
41
-
-
0035204427
-
A peptide carrier for the delivery of biologically active proteins into mammalian cells
-
Morris MC, Depollier J, Mery J, Heitz F, Divita G. A peptide carrier for the delivery of biologically active proteins into mammalian cells. Nat Biotechnol 2001; 19: 1173-6.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 1173-1176
-
-
Morris, M.C.1
Depollier, J.2
Mery, J.3
Heitz, F.4
Divita, G.5
-
42
-
-
25144520907
-
On the mechanisms of the internalization of S4(13)-PV cellpenetrating peptide
-
Mano M, Teodosio C, Paiva A, Simoes S, Pedroso de Lima MC. On the mechanisms of the internalization of S4(13)-PV cellpenetrating peptide. Biochem J 2005; 390: 603-12.
-
(2005)
Biochem J
, vol.390
, pp. 603-612
-
-
Mano, M.1
Teodosio, C.2
Paiva, A.3
Simoes, S.4
de Lima, M.C.P.5
-
43
-
-
0036663014
-
In vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis
-
Cao G, Pei W, Ge H, et al. In vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis. J Neurosci 2002; 22: 5423-31.
-
(2002)
J Neurosci
, vol.22
, pp. 5423-5431
-
-
Cao, G.1
Pei, W.2
Ge, H.3
-
44
-
-
0024209811
-
Autonomous functional domains of chemically synthesized human immunodeficiency virus tat transactivator protein
-
Green M, Loewenstein PM. Autonomous functional domains of chemically synthesized human immunodeficiency virus tat transactivator protein. Cell 1988; 55: 1179-88.
-
(1988)
Cell
, vol.55
, pp. 1179-1188
-
-
Green, M.1
Loewenstein, P.M.2
-
45
-
-
0028054797
-
Tat-mediated delivery of heterologous proteins into cells
-
Fawell S, Seery J, Daikh Y, et al. Tat-mediated delivery of heterologous proteins into cells. Proc Natl Acad Sci USA 1994; 91: 664-8.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 664-668
-
-
Fawell, S.1
Seery, J.2
Daikh, Y.3
-
46
-
-
13844256698
-
Tat peptide-mediated cellular delivery: Back to basics
-
Brooks H, Lebleu B, Vives E. Tat peptide-mediated cellular delivery: back to basics. Adv Drug Deliv Rev 2005; 57: 559-77.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 559-577
-
-
Brooks, H.1
Lebleu, B.2
Vives, E.3
-
47
-
-
0037340169
-
Transduction of a functional domain of the AT1 receptor in neurons by HIV-Tat PTD
-
Vazquez J, Sun C, Du J, Fuentes L, Sumners C, Raizada MK. Transduction of a functional domain of the AT1 receptor in neurons by HIV-Tat PTD. Hypertension 2003; 41: 751-6.
-
(2003)
Hypertension
, vol.41
, pp. 751-756
-
-
Vazquez, J.1
Sun, C.2
Du, J.3
Fuentes, L.4
Sumners, C.5
Raizada, M.K.6
-
48
-
-
63649084523
-
Delivery of therapeutic proteins as secretable TAT fusion products
-
Flinterman M, Farzaneh F, Habib N, Malik F, Gaken J, Tavassoli M. Delivery of therapeutic proteins as secretable TAT fusion products. Mol Ther 2009; 17: 334-42.
-
(2009)
Mol Ther
, vol.17
, pp. 334-342
-
-
Flinterman, M.1
Farzaneh, F.2
Habib, N.3
Malik, F.4
Gaken, J.5
Tavassoli, M.6
-
49
-
-
79958265908
-
Modified Tat peptide with cationic lipids enhances gene transfection efficiency via temperature-dependent and caveolaemediated endocytosis
-
Yamano S, Dai J, Yuvienco C, Khapli S, Moursi AM, Montclare JK. Modified Tat peptide with cationic lipids enhances gene transfection efficiency via temperature-dependent and caveolaemediated endocytosis. J Control Release 2011; 152: 278-85.
-
(2011)
J Control Release
, vol.152
, pp. 278-285
-
-
Yamano, S.1
Dai, J.2
Yuvienco, C.3
Khapli, S.4
Moursi, A.M.5
Montclare, J.K.6
-
50
-
-
5344234013
-
In vivo protein transduction: Biologically active intact pep-1-superoxide dismutase fusion protein efficiently protects against ischemic insult
-
Eum WS, Kim DW, Hwang IK, et al. In vivo protein transduction: biologically active intact pep-1-superoxide dismutase fusion protein efficiently protects against ischemic insult. Free Radic Biol Med 2004; 37: 1656-69.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 1656-1669
-
-
Eum, W.S.1
Kim, D.W.2
Hwang, I.K.3
-
51
-
-
38349191031
-
Effective delivery of Pep-1-cargo protein into ischemic neurons and long-term neuroprotection of Pep-1-SOD1 against ischemic injury in the gerbil hippocampus
-
Cho JH, Hwang IK, Yoo KY, et al. Effective delivery of Pep-1-cargo protein into ischemic neurons and long-term neuroprotection of Pep-1-SOD1 against ischemic injury in the gerbil hippocampus. Neurochem Int 2008; 52: 659-68.
-
(2008)
Neurochem Int
, vol.52
, pp. 659-668
-
-
Cho, J.H.1
Hwang, I.K.2
Yoo, K.Y.3
-
52
-
-
21344459081
-
Copper chaperone for Cu,Zn-SOD supplement potentiates the Cu,Zn-SOD function of neuroprotective effects against ischemic neuronal damage in the gerbil hippocampus
-
Hwang IK, Eum WS, Yoo KY, et al. Copper chaperone for Cu,Zn-SOD supplement potentiates the Cu,Zn-SOD function of neuroprotective effects against ischemic neuronal damage in the gerbil hippocampus. Free Radic Biol Med 2005; 39: 392-402.
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 392-402
-
-
Hwang, I.K.1
Eum, W.S.2
Yoo, K.Y.3
-
53
-
-
53049092441
-
Systemic administration of PEP-1-SOD1 fusion protein improves functional recovery by inhibition of neuronal cell death after spinal cord injury
-
Yune TY, Lee JY, Jiang MH, Kim DW, Choi SY, Oh TH. Systemic administration of PEP-1-SOD1 fusion protein improves functional recovery by inhibition of neuronal cell death after spinal cord injury. Free Radic Biol Med 2008; 45: 1190-200.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1190-1200
-
-
Yune, T.Y.1
Lee, J.Y.2
Jiang, M.H.3
Kim, D.W.4
Choi, S.Y.5
Oh, T.H.6
-
54
-
-
84856392744
-
Neuroprotective Effects of PEP-1-Cu,Zn-SOD against Ischemic Neuronal Damage in the Rabbit Spinal Cord
-
Kim W, Kim DW, Yoo DY, et al. Neuroprotective Effects of PEP-1-Cu,Zn-SOD against Ischemic Neuronal Damage in the Rabbit Spinal Cord. Neurochem Res 2012; 37(2): 307-13.
-
(2012)
Neurochem Res
, vol.37
, Issue.2
, pp. 307-313
-
-
Kim, W.1
Kim, D.W.2
Yoo, D.Y.3
-
55
-
-
33644852795
-
Transduced human copper chaperone for Cu,Zn-SOD (PEP-1-CCS) protects against neuronal cell death
-
Choi SH, Kim DW, Kim SY, et al. Transduced human copper chaperone for Cu,Zn-SOD (PEP-1-CCS) protects against neuronal cell death. Mol Cells 2005; 20: 401-8.
-
(2005)
Mol Cells
, vol.20
, pp. 401-408
-
-
Choi, S.H.1
Kim, D.W.2
Kim, S.Y.3
-
56
-
-
40349085911
-
Transduced human PEP-1-heat shock protein 27 efficiently protects against brain ischemic insult
-
An JJ, Lee YP, Kim SY, et al. Transduced human PEP-1-heat shock protein 27 efficiently protects against brain ischemic insult. Febs J 2008; 275: 1296-308.
-
(2008)
Febs J
, vol.275
, pp. 1296-1308
-
-
An, J.J.1
Lee, Y.P.2
Kim, S.Y.3
-
57
-
-
69249205350
-
Transduced human PEP-1-catalase fusion protein attenuates ischemic neuronal damage
-
Kim DW, Jeong HJ, Kang HW, et al. Transduced human PEP-1-catalase fusion protein attenuates ischemic neuronal damage. Free Radic Biol Med 2009; 47: 941-52.
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 941-952
-
-
Kim, D.W.1
Jeong, H.J.2
Kang, H.W.3
-
58
-
-
84863235982
-
Imipramine enhances neuroprotective effect of PEP-1-Catalase against ischemic neuronal damage
-
Kim DW, Kim DS, Kim MJ, et al. Imipramine enhances neuroprotective effect of PEP-1-Catalase against ischemic neuronal damage. BMB Rep 2011; 44: 647-52.
-
(2011)
BMB Rep
, vol.44
, pp. 647-652
-
-
Kim, D.W.1
Kim, D.S.2
Kim, M.J.3
-
59
-
-
0026784945
-
Antennapedia homeobox as a signal for the cellular internalization and nuclear addressing of a small exogenous peptide
-
Perez F, Joliot A, Bloch-Gallego E, Zahraoui A, Triller A, Prochiantz A. Antennapedia homeobox as a signal for the cellular internalization and nuclear addressing of a small exogenous peptide. J Cell Sci 1992; 102 (Pt 4): 717-22.
-
(1992)
J Cell Sci
, vol.102
, Issue.Pt. 4
, pp. 717-722
-
-
Perez, F.1
Joliot, A.2
Bloch-Gallego, E.3
Zahraoui, A.4
Triller, A.5
Prochiantz, A.6
-
60
-
-
0024407460
-
The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: Comparison with prokaryotic repressors
-
Qian YQ, Billeter M, Otting G, Muller M, Gehring WJ, Wuthrich K. The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: comparison with prokaryotic repressors. Cell 1989; 59: 573-80.
-
(1989)
Cell
, vol.59
, pp. 573-580
-
-
Qian, Y.Q.1
Billeter, M.2
Otting, G.3
Muller, M.4
Gehring, W.J.5
Wuthrich, K.6
-
61
-
-
28844482314
-
Apoptosis inhibition in ischemic brain by intraperitoneal PTD-BIR3-RING (XIAP)
-
Fan YF, Lu CZ, Xie J, Zhao YX, Yang GY. Apoptosis inhibition in ischemic brain by intraperitoneal PTD-BIR3-RING (XIAP). Neurochem Int 2006; 48: 50-9.
-
(2006)
Neurochem Int
, vol.48
, pp. 50-59
-
-
Fan, Y.F.1
Lu, C.Z.2
Xie, J.3
Zhao, Y.X.4
Yang, G.Y.5
-
62
-
-
33947541241
-
Pretreatment with PTD-calbindin D 28k alleviates rat brain injury induced by ischemia and reperfusion
-
Fan Y, Shi L, Gu Y, et al. Pretreatment with PTD-calbindin D 28k alleviates rat brain injury induced by ischemia and reperfusion. J Cereb Blood Flow Metab 2007; 27: 719-28.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 719-728
-
-
Fan, Y.1
Shi, L.2
Gu, Y.3
-
63
-
-
33748468538
-
Gene delivery into brain capillary endothelial cells using Antp-modified DNA-loaded nanoparticles
-
Huang R, Yang W, Jiang C, Pei Y. Gene delivery into brain capillary endothelial cells using Antp-modified DNA-loaded nanoparticles. Chem Pharm Bull (Tokyo) 2006; 54: 1254-8.
-
(2006)
Chem Pharm Bull (Tokyo)
, vol.54
, pp. 1254-1258
-
-
Huang, R.1
Yang, W.2
Jiang, C.3
Pei, Y.4
-
64
-
-
0029295070
-
Determination of disulphide bridges in PG-2, an antimicrobial peptide from porcine leukocytes
-
Harwig SS, Swiderek KM, Lee TD, Lehrer RI. Determination of disulphide bridges in PG-2, an antimicrobial peptide from porcine leukocytes. J Pept Sci 1995; 1: 207-15.
-
(1995)
J Pept Sci
, vol.1
, pp. 207-215
-
-
Harwig, S.S.1
Swiderek, K.M.2
Lee, T.D.3
Lehrer, R.I.4
-
65
-
-
0029886161
-
Synthesis and solution structure of the antimicrobial peptide protegrin-1
-
Aumelas A, Mangoni M, Roumestand C, et al. Synthesis and solution structure of the antimicrobial peptide protegrin-1. Eur J Biochem 1996; 237: 575-83.
-
(1996)
Eur J Biochem
, vol.237
, pp. 575-583
-
-
Aumelas, A.1
Mangoni, M.2
Roumestand, C.3
-
66
-
-
0032774790
-
Membrane channel formation by antimicrobial protegrins
-
Sokolov Y, Mirzabekov T, Martin DW, Lehrer RI, Kagan BL. Membrane channel formation by antimicrobial protegrins. Biochim Biophys Acta 1999; 1420: 23-9.
-
(1999)
Biochim Biophys Acta
, vol.1420
, pp. 23-29
-
-
Sokolov, Y.1
Mirzabekov, T.2
Martin, D.W.3
Lehrer, R.I.4
Kagan, B.L.5
-
67
-
-
0035196836
-
Enhanced delivery of doxorubicin into the brain via a peptide-vector-mediated strategy: Saturation kinetics and specificity
-
Rousselle C, Smirnova M, Clair P, et al. Enhanced delivery of doxorubicin into the brain via a peptide-vector-mediated strategy: saturation kinetics and specificity. J Pharmacol Exp Ther 2001; 296: 124-31.
-
(2001)
J Pharmacol Exp Ther
, vol.296
, pp. 124-131
-
-
Rousselle, C.1
Smirnova, M.2
Clair, P.3
-
68
-
-
0035984819
-
Improved brain delivery of benzylpenicillin with a peptide-vector-mediated strategy
-
Rousselle C, Clair P, Temsamani J, Scherrmann JM. Improved brain delivery of benzylpenicillin with a peptide-vector-mediated strategy. J Drug Target 2002; 10: 309-15.
-
(2002)
J Drug Target
, vol.10
, pp. 309-315
-
-
Rousselle, C.1
Clair, P.2
Temsamani, J.3
Scherrmann, J.M.4
-
69
-
-
0038340924
-
Improved brain uptake and pharmacological activity of dalargin using a peptide-vectormediated strategy
-
Rousselle C, Clair P, Smirnova M, et al. Improved brain uptake and pharmacological activity of dalargin using a peptide-vectormediated strategy. J Pharmacol Exp Ther 2003; 306: 371-6.
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 371-376
-
-
Rousselle, C.1
Clair, P.2
Smirnova, M.3
-
70
-
-
85046914841
-
Peptide delivery to the brain via adsorptive-mediated endocytosis: Advances with SynB vectors
-
Drin G, Rousselle C, Scherrmann JM, Rees AR, Temsamani J. Peptide delivery to the brain via adsorptive-mediated endocytosis: advances with SynB vectors. AAPS PharmSci 2002; 4: E26.
-
(2002)
AAPS PharmSci
, vol.4
-
-
Drin, G.1
Rousselle, C.2
Scherrmann, J.M.3
Rees, A.R.4
Temsamani, J.5
-
71
-
-
82855172080
-
The design and delivery of a thermally responsive peptide to inhibit S100B-mediated neurodegeneration
-
Hearst SM, Walker LR, Shao Q, Lopez M, Raucher D, Vig PJ. The design and delivery of a thermally responsive peptide to inhibit S100B-mediated neurodegeneration. Neuroscience 2011; 197: 369-80.
-
(2011)
Neuroscience
, vol.197
, pp. 369-380
-
-
Hearst, S.M.1
Walker, L.R.2
Shao, Q.3
Lopez, M.4
Raucher, D.5
Vig, P.J.6
-
72
-
-
0346460957
-
Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake
-
Richard JP, Melikov K, Vives E, et al. Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. J Biol Chem 2003; 278: 585-90.
-
(2003)
J Biol Chem
, vol.278
, pp. 585-590
-
-
Richard, J.P.1
Melikov, K.2
Vives, E.3
-
73
-
-
79960833324
-
Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum
-
Du L, Kayali R, Bertoni C, et al. Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum. Hum Mol Genet 2011; 20: 3151-60.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 3151-3160
-
-
Du, L.1
Kayali, R.2
Bertoni, C.3
-
74
-
-
78650672128
-
Nucleolar localization signals of LIM kinase 2 function as a cell-penetrating peptide
-
Kobayashi N, Niwa M, Hao Y, Yoshida T. Nucleolar localization signals of LIM kinase 2 function as a cell-penetrating peptide. Protein Pept Lett 2010; 17: 1480-8.
-
(2010)
Protein Pept Lett
, vol.17
, pp. 1480-1488
-
-
Kobayashi, N.1
Niwa, M.2
Hao, Y.3
Yoshida, T.4
-
75
-
-
0021130764
-
Transferrin receptor on endothelium of brain capillaries
-
Jefferies WA, Brandon MR, Hunt SV, Williams AF, Gatter KC, Mason DY. Transferrin receptor on endothelium of brain capillaries. Nature 1984; 312: 162-3.
-
(1984)
Nature
, vol.312
, pp. 162-163
-
-
Jefferies, W.A.1
Brandon, M.R.2
Hunt, S.V.3
Williams, A.F.4
Gatter, K.C.5
Mason, D.Y.6
-
76
-
-
0033082752
-
Non-invasive drug delivery to the human brain using endogenous blood-brain barrier transport systems
-
Pardridge WM. Non-invasive drug delivery to the human brain using endogenous blood-brain barrier transport systems. Pharm Sci Technolo Today 1999; 2: 49-59.
-
(1999)
Pharm Sci Technolo Today
, vol.2
, pp. 49-59
-
-
Pardridge, W.M.1
-
77
-
-
0034988984
-
Neuroprotection in transient focal brain ischemia after delayed intravenous administration of brain-derived neurotrophic factor conjugated to a blood-brain barrier drug targeting system
-
Zhang Y, Pardridge WM. Neuroprotection in transient focal brain ischemia after delayed intravenous administration of brain-derived neurotrophic factor conjugated to a blood-brain barrier drug targeting system. Stroke 2001; 32: 1378-84.
-
(2001)
Stroke
, vol.32
, pp. 1378-1384
-
-
Zhang, Y.1
Pardridge, W.M.2
-
78
-
-
0033524392
-
Neuroprotection with noninvasive neurotrophin delivery to the brain
-
Wu D, Pardridge WM. Neuroprotection with noninvasive neurotrophin delivery to the brain. Proc Natl Acad Sci USA 1999; 96: 254-9.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 254-259
-
-
Wu, D.1
Pardridge, W.M.2
-
79
-
-
0036228917
-
Enhanced neuroprotective effects of basic fibroblast growth factor in regional brain ischemia after conjugation to a blood-brain barrier delivery vector
-
Song BW, Vinters HV, Wu D, Pardridge WM. Enhanced neuroprotective effects of basic fibroblast growth factor in regional brain ischemia after conjugation to a blood-brain barrier delivery vector. J Pharmacol Exp Ther 2002; 301: 605-10.
-
(2002)
J Pharmacol Exp Ther
, vol.301
, pp. 605-610
-
-
Song, B.W.1
Vinters, H.V.2
Wu, D.3
Pardridge, W.M.4
-
80
-
-
77952329581
-
Drug targeting of erythropoietin across the primate blood-brain barrier with an IgG molecular Trojan horse
-
Boado RJ, Hui EK, Lu JZ, Pardridge WM. Drug targeting of erythropoietin across the primate blood-brain barrier with an IgG molecular Trojan horse. J Pharmacol Exp Ther; 333: 961-9.
-
J Pharmacol Exp Ther
, vol.333
, pp. 961-969
-
-
Boado, R.J.1
Hui, E.K.2
Lu, J.Z.3
Pardridge, W.M.4
-
81
-
-
77957944896
-
Neuroprotection in experimental stroke in the rat with an IgG-erythropoietin fusion protein
-
Fu A, Hui EK, Lu JZ, Boado RJ, Pardridge WM. Neuroprotection in experimental stroke in the rat with an IgG-erythropoietin fusion protein. Brain Res 2010; 1360: 193-7.
-
(2010)
Brain Res
, vol.1360
, pp. 193-197
-
-
Fu, A.1
Hui, E.K.2
Lu, J.Z.3
Boado, R.J.4
Pardridge, W.M.5
-
82
-
-
44449128659
-
GDNF fusion protein for targeted-drug delivery across the human blood-brain barrier
-
Boado RJ, Zhang Y, Wang Y, Pardridge WM. GDNF fusion protein for targeted-drug delivery across the human blood-brain barrier. Biotechnol Bioeng 2008; 100: 387-96.
-
(2008)
Biotechnol Bioeng
, vol.100
, pp. 387-396
-
-
Boado, R.J.1
Zhang, Y.2
Wang, Y.3
Pardridge, W.M.4
-
83
-
-
0037168589
-
Protection against ischemic brain injury by protein therapeutics
-
Asoh S, Ohsawa I, Mori T, et al. Protection against ischemic brain injury by protein therapeutics. Proc Natl Acad Sci USA 2002; 99: 17107-12.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 17107-17112
-
-
Asoh, S.1
Ohsawa, I.2
Mori, T.3
-
84
-
-
0037335187
-
Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles
-
Kreuter J, Ramge P, Petrov V, et al. Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles. Pharm Res 2003; 20: 409-16.
-
(2003)
Pharm Res
, vol.20
, pp. 409-416
-
-
Kreuter, J.1
Ramge, P.2
Petrov, V.3
-
85
-
-
59649102668
-
Transferrin-and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood-brain barrier (BBB)
-
Ulbrich K, Hekmatara T, Herbert E, Kreuter J. Transferrin-and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood-brain barrier (BBB). Eur J Pharm Biopharm 2009; 71: 251-6.
-
(2009)
Eur J Pharm Biopharm
, vol.71
, pp. 251-256
-
-
Ulbrich, K.1
Hekmatara, T.2
Herbert, E.3
Kreuter, J.4
-
86
-
-
33646796753
-
Covalent linkage of apolipoprotein e to albumin nanoparticles strongly enhances drug transport into the brain
-
Michaelis K, Hoffmann MM, Dreis S, et al. Covalent linkage of apolipoprotein e to albumin nanoparticles strongly enhances drug transport into the brain. J Pharmacol Exp Ther 2006; 317: 1246-53.
-
(2006)
J Pharmacol Exp Ther
, vol.317
, pp. 1246-1253
-
-
Michaelis, K.1
Hoffmann, M.M.2
Dreis, S.3
-
87
-
-
0037168963
-
Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma
-
Gelperina SE, Khalansky AS, Skidan IN, et al. Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma. Toxicol Lett 2002; 126: 131-41.
-
(2002)
Toxicol Lett
, vol.126
, pp. 131-141
-
-
Gelperina, S.E.1
Khalansky, A.S.2
Skidan, I.N.3
-
88
-
-
68149160611
-
Nanoparticle-mediated delivery of superoxide dismutase to the brain: An effective strategy to reduce ischemia-reperfusion injury
-
Reddy MK, Labhasetwar V. Nanoparticle-mediated delivery of superoxide dismutase to the brain: an effective strategy to reduce ischemia-reperfusion injury. FASEB J 2009; 23: 1384-95.
-
(2009)
FASEB J
, vol.23
, pp. 1384-1395
-
-
Reddy, M.K.1
Labhasetwar, V.2
-
89
-
-
80054795004
-
Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma
-
Agemy L, Friedmann-Morvinski D, Kotamraju VR, et al. Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma. Proc Natl Acad Sci USA; 108: 17450-5.
-
Proc Natl Acad Sci USA
, vol.108
, pp. 17450-17455
-
-
Agemy, L.1
Friedmann-Morvinski, D.2
Kotamraju, V.R.3
-
90
-
-
40849097322
-
Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease
-
Wilson B, Samanta MK, Santhi K, Kumar KP, Paramakrishnan N, Suresh B. Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease. Brain Res 2008; 1200: 159-68.
-
(2008)
Brain Res
, vol.1200
, pp. 159-168
-
-
Wilson, B.1
Samanta, M.K.2
Santhi, K.3
Kumar, K.P.4
Paramakrishnan, N.5
Suresh, B.6
-
91
-
-
70350464733
-
Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles
-
Kurakhmaeva KB, Djindjikhashvili IA, Petrov VE, et al. Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles. J Drug Target 2009; 17: 564-74.
-
(2009)
J Drug Target
, vol.17
, pp. 564-574
-
-
Kurakhmaeva, K.B.1
Djindjikhashvili, I.A.2
Petrov, V.E.3
-
92
-
-
68949208465
-
Nanocarriers' entry into the cell: Relevance to drug delivery
-
Hillaireau H, Couvreur P. Nanocarriers' entry into the cell: relevance to drug delivery. Cell Mol Life Sci 2009; 66: 2873-96.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2873-2896
-
-
Hillaireau, H.1
Couvreur, P.2
-
93
-
-
0035984812
-
Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier
-
Kreuter J, Shamenkov D, Petrov V, et al. Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier. J Drug Target 2002; 10: 317-25.
-
(2002)
J Drug Target
, vol.10
, pp. 317-325
-
-
Kreuter, J.1
Shamenkov, D.2
Petrov, V.3
-
94
-
-
77955171756
-
Macrophage-mediated GDNF delivery protects against dopaminergic neurodegeneration: A therapeutic strategy for Parkinson's disease
-
Biju K, Zhou Q, Li G, et al. Macrophage-mediated GDNF delivery protects against dopaminergic neurodegeneration: a therapeutic strategy for Parkinson's disease. Mol Ther 2010; 18: 1536-44.
-
(2010)
Mol Ther
, vol.18
, pp. 1536-1544
-
-
Biju, K.1
Zhou, Q.2
Li, G.3
-
95
-
-
80052642756
-
Photothermal treatment of glioma; an in vitro study of macrophage-mediated delivery of gold nanoshells
-
Baek SK, Makkouk AR, Krasieva T, Sun CH, Madsen SJ, Hirschberg H. Photothermal treatment of glioma; an in vitro study of macrophage-mediated delivery of gold nanoshells. J Neurooncol 2011; 104: 439-48.
-
(2011)
J Neurooncol
, vol.104
, pp. 439-448
-
-
Baek, S.K.1
Makkouk, A.R.2
Krasieva, T.3
Sun, C.H.4
Madsen, S.J.5
Hirschberg, H.6
-
96
-
-
0033512004
-
Inflammatory mediators and stroke: New opportunities for novel therapeutics
-
Barone FC, Feuerstein GZ. Inflammatory mediators and stroke: new opportunities for novel therapeutics. J Cereb Blood Flow Metab 1999; 19: 819-34.
-
(1999)
J Cereb Blood Flow Metab
, vol.19
, pp. 819-834
-
-
Barone, F.C.1
Feuerstein, G.Z.2
-
97
-
-
78650950140
-
TAT-mediated delivery of neuroglobin protects against focal cerebral ischemia in mice
-
Cai B, Lin Y, Xue XH, Fang L, Wang N, Wu ZY. TAT-mediated delivery of neuroglobin protects against focal cerebral ischemia in mice. Exp Neurol 2011; 227: 224-31.
-
(2011)
Exp Neurol
, vol.227
, pp. 224-231
-
-
Cai, B.1
Lin, Y.2
Xue, X.H.3
Fang, L.4
Wang, N.5
Wu, Z.Y.6
-
98
-
-
0036829818
-
Intravenous TAT-Bcl-Xl is protective after middle cerebral artery occlusion in mice
-
Kilic E, Dietz GP, Hermann DM, Bahr M. Intravenous TAT-Bcl-Xl is protective after middle cerebral artery occlusion in mice. Ann Neurol 2002; 52: 617-22.
-
(2002)
Ann Neurol
, vol.52
, pp. 617-622
-
-
Kilic, E.1
Dietz, G.P.2
Hermann, D.M.3
Bahr, M.4
-
99
-
-
0038304351
-
Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice
-
Kilic U, Kilic E, Dietz GP, Bahr M. Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice. Stroke 2003; 34: 1304-10.
-
(2003)
Stroke
, vol.34
, pp. 1304-1310
-
-
Kilic, U.1
Kilic, E.2
Dietz, G.P.3
Bahr, M.4
-
100
-
-
33645075706
-
PTD-XIAP protects against cerebral ischemia by anti-apoptotic and transcriptional regulatory mechanisms
-
Guegan C, Braudeau J, Couriaud C, et al. PTD-XIAP protects against cerebral ischemia by anti-apoptotic and transcriptional regulatory mechanisms. Neurobiol Dis 2006; 22: 177-86.
-
(2006)
Neurobiol Dis
, vol.22
, pp. 177-186
-
-
Guegan, C.1
Braudeau, J.2
Couriaud, C.3
-
101
-
-
33947315308
-
DeltaPKC mediates microcerebrovascular dysfunction in acute ischemia and in chronic hypertensive stress in vivo
-
Bright R, Steinberg GK, Mochly-Rosen D. DeltaPKC mediates microcerebrovascular dysfunction in acute ischemia and in chronic hypertensive stress in vivo. Brain Res 2007; 1144: 146-55.
-
(2007)
Brain Res
, vol.1144
, pp. 146-155
-
-
Bright, R.1
Steinberg, G.K.2
Mochly-Rosen, D.3
-
102
-
-
62149092900
-
TAT-Bcl-x(L) improves survival of neuronal precursor cells in the lesioned striatum after focal cerebral ischemia
-
Doeppner TR, Dietz GP, El Aanbouri M, et al. TAT-Bcl-x(L) improves survival of neuronal precursor cells in the lesioned striatum after focal cerebral ischemia. Neurobiol Dis 2009; 34: 87-94.
-
(2009)
Neurobiol Dis
, vol.34
, pp. 87-94
-
-
Doeppner, T.R.1
Dietz, G.P.2
El Aanbouri, M.3
-
103
-
-
77955846317
-
Transplantation of TAT-Bcl-xL-transduced neural precursor cells: Long-term neuroprotection after stroke
-
Doeppner TR, El Aanbouri M, Dietz GP, Weise J, Schwarting S, Bahr M. Transplantation of TAT-Bcl-xL-transduced neural precursor cells: long-term neuroprotection after stroke. Neurobiol Dis; 40: 265-76.
-
Neurobiol Dis
, vol.40
, pp. 265-276
-
-
Doeppner, T.R.1
El Aanbouri, M.2
Dietz, G.P.3
Weise, J.4
Schwarting, S.5
Bahr, M.6
-
104
-
-
33745215642
-
Gene expression patterns for GDNF and its receptors in the human putamen affected by Parkinson's disease: A real-time PCR study
-
Backman CM, Shan L, Zhang YJ, et al. Gene expression patterns for GDNF and its receptors in the human putamen affected by Parkinson's disease: a real-time PCR study. Mol Cell Endocrinol 2006; 252: 160-6.
-
(2006)
Mol Cell Endocrinol
, vol.252
, pp. 160-166
-
-
Backman, C.M.1
Shan, L.2
Zhang, Y.J.3
-
105
-
-
0034641710
-
Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury
-
Brines ML, Ghezzi P, Keenan S, et al. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci USA 2000; 97: 10526-31.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10526-10531
-
-
Brines, M.L.1
Ghezzi, P.2
Keenan, S.3
-
106
-
-
0036705708
-
Erythropoietin therapy for acute stroke is both safe and beneficial
-
Ehrenreich H, Hasselblatt M, Dembowski C, et al. Erythropoietin therapy for acute stroke is both safe and beneficial. Mol Med 2002; 8: 495-505.
-
(2002)
Mol Med
, vol.8
, pp. 495-505
-
-
Ehrenreich, H.1
Hasselblatt, M.2
Dembowski, C.3
-
107
-
-
6944237300
-
Erythropoietin mediates tissue protection through an erythropoietin and common betasubunit heteroreceptor
-
Brines M, Grasso G, Fiordaliso F, et al. Erythropoietin mediates tissue protection through an erythropoietin and common betasubunit heteroreceptor. Proc Natl Acad Sci USA 2004; 101: 14907-12.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 14907-14912
-
-
Brines, M.1
Grasso, G.2
Fiordaliso, F.3
-
108
-
-
33646357765
-
Erythropoietin protects CA1 neurons against global cerebral ischemia in rat: Potential signaling mechanisms
-
Zhang F, Signore AP, Zhou Z, Wang S, Cao G, Chen J. Erythropoietin protects CA1 neurons against global cerebral ischemia in rat: potential signaling mechanisms. J Neurosci Res 2006; 83: 1241-51.
-
(2006)
J Neurosci Res
, vol.83
, pp. 1241-1251
-
-
Zhang, F.1
Signore, A.P.2
Zhou, Z.3
Wang, S.4
Cao, G.5
Chen, J.6
-
109
-
-
0033959837
-
Induction of protein kinase Cdelta subspecies in neurons and microglia after transient global brain ischemia
-
Koponen S, Goldsteins G, Keinanen R, Koistinaho J. Induction of protein kinase Cdelta subspecies in neurons and microglia after transient global brain ischemia. J Cereb Blood Flow Metab 2000; 20: 93-102.
-
(2000)
J Cereb Blood Flow Metab
, vol.20
, pp. 93-102
-
-
Koponen, S.1
Goldsteins, G.2
Keinanen, R.3
Koistinaho, J.4
-
110
-
-
0037246123
-
Regulation of cell apoptosis by protein kinase c delta
-
Brodie C, Blumberg PM. Regulation of cell apoptosis by protein kinase c delta. Apoptosis 2003; 8: 19-27.
-
(2003)
Apoptosis
, vol.8
, pp. 19-27
-
-
Brodie, C.1
Blumberg, P.M.2
-
111
-
-
0034698182
-
Mitochondrial translocation of protein kinase C delta in phorbol ester-induced cytochrome c release and apoptosis
-
Majumder PK, Pandey P, Sun X, et al. Mitochondrial translocation of protein kinase C delta in phorbol ester-induced cytochrome c release and apoptosis. J Biol Chem 2000; 275: 21793-6.
-
(2000)
J Biol Chem
, vol.275
, pp. 21793-21796
-
-
Majumder, P.K.1
Pandey, P.2
Sun, X.3
-
112
-
-
39449092458
-
Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction
-
Bates E, Bode C, Costa M, et al. Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction. Circulation 2008; 117: 886-96.
-
(2008)
Circulation
, vol.117
, pp. 886-896
-
-
Bates, E.1
Bode, C.2
Costa, M.3
-
113
-
-
33846614162
-
Epsilon PKC may contribute to the protective effect of hypothermia in a rat focal cerebral ischemia model
-
Shimohata T, Zhao H, Steinberg GK. Epsilon PKC may contribute to the protective effect of hypothermia in a rat focal cerebral ischemia model. Stroke 2007; 38: 375-80.
-
(2007)
Stroke
, vol.38
, pp. 375-380
-
-
Shimohata, T.1
Zhao, H.2
Steinberg, G.K.3
-
114
-
-
78650214094
-
Post-ischemic activation of protein kinase C epsilon protects the hippocampus from cerebral ischemic injury via alterations in cerebral blood flow
-
Della-Morte D, Raval AP, Dave KR, Lin HW, Perez-Pinzon MA. Post-ischemic activation of protein kinase C epsilon protects the hippocampus from cerebral ischemic injury via alterations in cerebral blood flow. Neurosci Lett 2011; 487: 158-62.
-
(2011)
Neurosci Lett
, vol.487
, pp. 158-162
-
-
Della-Morte, D.1
Raval, A.P.2
Dave, K.R.3
Lin, H.W.4
Perez-Pinzon, M.A.5
-
115
-
-
0141724805
-
A peptide inhibitor of c-Jun Nterminal kinase protects against excitotoxicity and cerebral ischemia
-
Borsello T, Clarke PG, Hirt L, et al. A peptide inhibitor of c-Jun Nterminal kinase protects against excitotoxicity and cerebral ischemia. Nat Med 2003; 9: 1180-6.
-
(2003)
Nat Med
, vol.9
, pp. 1180-1186
-
-
Borsello, T.1
Clarke, P.G.2
Hirt, L.3
-
116
-
-
36649004091
-
Time-course of c-Jun Nterminal kinase activation after cerebral ischemia and effect of DJNKI1 on c-Jun and caspase-3 activation
-
Repici M, Centeno C, Tomasi S, et al. Time-course of c-Jun Nterminal kinase activation after cerebral ischemia and effect of DJNKI1 on c-Jun and caspase-3 activation. Neuroscience 2007; 150: 40-9.
-
(2007)
Neuroscience
, vol.150
, pp. 40-49
-
-
Repici, M.1
Centeno, C.2
Tomasi, S.3
-
117
-
-
50049117240
-
The JNK inhibitor XG-102 protects from ischemic damage with delayed intravenous administration also in the presence of recombinant tissue plasminogen activator
-
Wiegler K, Bonny C, Coquoz D, Hirt L. The JNK inhibitor XG-102 protects from ischemic damage with delayed intravenous administration also in the presence of recombinant tissue plasminogen activator. Cerebrovasc Dis 2008; 26: 360-6.
-
(2008)
Cerebrovasc Dis
, vol.26
, pp. 360-366
-
-
Wiegler, K.1
Bonny, C.2
Coquoz, D.3
Hirt, L.4
-
118
-
-
0035030492
-
The postsynaptic NMDA-receptor--PSD-95 signaling complex in excitatory synapses of the brain
-
Sheng M. The postsynaptic NMDA-receptor--PSD-95 signaling complex in excitatory synapses of the brain. J Cell Sci 2001; 114: 1251.
-
(2001)
J Cell Sci
, vol.114
, pp. 1251
-
-
Sheng, M.1
-
119
-
-
0037174635
-
Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions
-
Aarts M, Liu Y, Liu L, et al. Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions. Science 2002; 298: 846-50.
-
(2002)
Science
, vol.298
, pp. 846-850
-
-
Aarts, M.1
Liu, Y.2
Liu, L.3
-
120
-
-
52449107081
-
Effectiveness of PSD95 inhibitors in permanent and transient focal ischemia in the rat
-
Sun HS, Doucette TA, Liu Y, et al. Effectiveness of PSD95 inhibitors in permanent and transient focal ischemia in the rat. Stroke 2008; 39: 2544-53.
-
(2008)
Stroke
, vol.39
, pp. 2544-2553
-
-
Sun, H.S.1
Doucette, T.A.2
Liu, Y.3
-
121
-
-
0035909992
-
Neuroglobin is upregulated by and protects neurons from hypoxic-ischemic injury
-
Sun Y, Jin K, Mao XO, Zhu Y, Greenberg DA. Neuroglobin is upregulated by and protects neurons from hypoxic-ischemic injury. Proc Natl Acad Sci USA 2001; 98: 15306-11.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 15306-15311
-
-
Sun, Y.1
Jin, K.2
Mao, X.O.3
Zhu, Y.4
Greenberg, D.A.5
-
122
-
-
78650545994
-
TAT-NEP1-40 as a novel therapeutic candidate for axonal regeneration and functional recovery after stroke
-
Gou X, Wang Q, Yang Q, Xu L, Xiong L. TAT-NEP1-40 as a novel therapeutic candidate for axonal regeneration and functional recovery after stroke. J Drug Target 2011; 19: 86-95.
-
(2011)
J Drug Target
, vol.19
, pp. 86-95
-
-
Gou, X.1
Wang, Q.2
Yang, Q.3
Xu, L.4
Xiong, L.5
-
123
-
-
45149105240
-
Trans-activator of transcriptionmediated delivery of NEP1-40 protein into brain has a neuroprotective effect against focal cerebral ischemic injury via inhibition of neuronal apoptosis
-
Wang Q, Gou X, Xiong L, et al. Trans-activator of transcriptionmediated delivery of NEP1-40 protein into brain has a neuroprotective effect against focal cerebral ischemic injury via inhibition of neuronal apoptosis. Anesthesiology 2008; 108: 1071-80.
-
(2008)
Anesthesiology
, vol.108
, pp. 1071-1080
-
-
Wang, Q.1
Gou, X.2
Xiong, L.3
-
124
-
-
67349287017
-
TAT-Hsp70-mediated neuroprotection and increased survival of neuronal precursor cells after focal cerebral ischemia in mice
-
Doeppner TR, Nagel F, Dietz GP, et al. TAT-Hsp70-mediated neuroprotection and increased survival of neuronal precursor cells after focal cerebral ischemia in mice. J Cereb Blood Flow Metab 2009; 29: 1187-96.
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, pp. 1187-1196
-
-
Doeppner, T.R.1
Nagel, F.2
Dietz, G.P.3
-
125
-
-
81255199283
-
Protective effects of intraperitoneal injection of TAT-SOD against focal cerebral ischemia/reperfusion injury in rats
-
Ye N, Liu S, Lin Y, Rao P. Protective effects of intraperitoneal injection of TAT-SOD against focal cerebral ischemia/reperfusion injury in rats. Life Sci 2011; 89: 868-74.
-
(2011)
Life Sci
, vol.89
, pp. 868-874
-
-
Ye, N.1
Liu, S.2
Lin, Y.3
Rao, P.4
-
126
-
-
30744434357
-
TAT-mediated delivery of BclxL protein is neuroprotective against neonatal hypoxic-ischemic brain injury via inhibition of caspases and AIF
-
Yin W, Cao G, Johnnides MJ, et al. TAT-mediated delivery of BclxL protein is neuroprotective against neonatal hypoxic-ischemic brain injury via inhibition of caspases and AIF. Neurobiol Dis 2006; 21: 358-71.
-
(2006)
Neurobiol Dis
, vol.21
, pp. 358-371
-
-
Yin, W.1
Cao, G.2
Johnnides, M.J.3
-
127
-
-
33645841626
-
Application of a bloodbrain-barrier-penetrating form of GDNF in a mouse model for Parkinson's disease
-
Dietz GP, Valbuena PC, Dietz B, et al. Application of a bloodbrain-barrier-penetrating form of GDNF in a mouse model for Parkinson's disease. Brain Res 2006; 1082: 61-6.
-
(2006)
Brain Res
, vol.1082
, pp. 61-66
-
-
Dietz, G.P.1
Valbuena, P.C.2
Dietz, B.3
-
128
-
-
77953615910
-
Inhibition of the JNK/AP-1 pathway reduces neuronal death and improves behavioral outcome after neonatal hypoxicischemic brain injury
-
Nijboer CH, van der Kooij MA, van Bel F, Ohl F, Heijnen CJ, Kavelaars A. Inhibition of the JNK/AP-1 pathway reduces neuronal death and improves behavioral outcome after neonatal hypoxicischemic brain injury. Brain Behav Immun 2010; 24: 812-21.
-
(2010)
Brain Behav Immun
, vol.24
, pp. 812-821
-
-
Nijboer, C.H.1
van der Kooij, M.A.2
van Bel, F.3
Ohl, F.4
Heijnen, C.J.5
Kavelaars, A.6
-
129
-
-
68249157084
-
Neuroprotection after status epilepticus by targeting protein interactions with postsynaptic density protein 95
-
Dykstra CM, Ratnam M, Gurd JW. Neuroprotection after status epilepticus by targeting protein interactions with postsynaptic density protein 95. J Neuropathol Exp Neurol 2009; 68: 823-31.
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 823-831
-
-
Dykstra, C.M.1
Ratnam, M.2
Gurd, J.W.3
-
130
-
-
42249103388
-
Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson's disease
-
Nagel F, Falkenburger BH, Tonges L, et al. Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson's disease. J Neurochem 2008; 105: 853-64.
-
(2008)
J Neurochem
, vol.105
, pp. 853-864
-
-
Nagel, F.1
Falkenburger, B.H.2
Tonges, L.3
-
131
-
-
22844432469
-
Transduced Tat-SOD fusion protein protects against ischemic brain injury
-
Kim DW, Eum WS, Jang SH, et al. Transduced Tat-SOD fusion protein protects against ischemic brain injury. Mol Cells 2005; 19: 88-96.
-
(2005)
Mol Cells
, vol.19
, pp. 88-96
-
-
Kim, D.W.1
Eum, W.S.2
Jang, S.H.3
-
132
-
-
74049160362
-
Neuroprotection against hypoxicischemic brain injury by inhibiting the apoptotic protease activating factor-1 pathway
-
Gao Y, Liang W, Hu X, et al. Neuroprotection against hypoxicischemic brain injury by inhibiting the apoptotic protease activating factor-1 pathway. Stroke 2010; 41: 166-72.
-
(2010)
Stroke
, vol.41
, pp. 166-172
-
-
Gao, Y.1
Liang, W.2
Hu, X.3
-
133
-
-
70349658528
-
Alternate pathways preserve tumor necrosis factor-alpha production after nuclear factor-kappaB inhibition in neonatal cerebral hypoxia-ischemia
-
Nijboer CH, Heijnen CJ, Groenendaal F, van Bel F, Kavelaars A. Alternate pathways preserve tumor necrosis factor-alpha production after nuclear factor-kappaB inhibition in neonatal cerebral hypoxia-ischemia. Stroke 2009; 40: 3362-8.
-
(2009)
Stroke
, vol.40
, pp. 3362-3368
-
-
Nijboer, C.H.1
Heijnen, C.J.2
Groenendaal, F.3
van Bel, F.4
Kavelaars, A.5
-
134
-
-
77958154973
-
Cell biology meets biophysics to unveil the different mechanisms of penetratin internalization in cells
-
Alves ID, Jiao CY, Aubry S, et al. Cell biology meets biophysics to unveil the different mechanisms of penetratin internalization in cells. Biochim Biophys Acta 2010; 1798: 2231-9.
-
(2010)
Biochim Biophys Acta
, vol.1798
, pp. 2231-2239
-
-
Alves, I.D.1
Jiao, C.Y.2
Aubry, S.3
-
135
-
-
77249139921
-
Transduced Tat-SAG fusion protein protects against oxidative stress and brain ischemic insult
-
Kim DW, Lee SH, Jeong MS, et al. Transduced Tat-SAG fusion protein protects against oxidative stress and brain ischemic insult. Free Radic Biol Med 2010; 48: 969-77.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 969-977
-
-
Kim, D.W.1
Lee, S.H.2
Jeong, M.S.3
-
136
-
-
76749145109
-
Tat-modified leptin is more accessible to hypothalamus through brain-blood barrier with a significant inhibition of body-weight gain in high-fat-diet fed mice
-
Zhang C, Su Z, Zhao B, et al. Tat-modified leptin is more accessible to hypothalamus through brain-blood barrier with a significant inhibition of body-weight gain in high-fat-diet fed mice. Exp Clin Endocrinol Diabetes 2010; 118: 31-7.
-
(2010)
Exp Clin Endocrinol Diabetes
, vol.118
, pp. 31-37
-
-
Zhang, C.1
Su, Z.2
Zhao, B.3
-
137
-
-
79951671130
-
Successful TAT-mediated enzyme replacement therapy in a mouse model of mitochondrial E3 deficiency
-
Rapoport M, Salman L, Sabag O, Patel MS, Lorberboum-Galski H. Successful TAT-mediated enzyme replacement therapy in a mouse model of mitochondrial E3 deficiency. J Mol Med (Berl) 2011; 89: 161-70.
-
(2011)
J Mol Med (Berl)
, vol.89
, pp. 161-170
-
-
Rapoport, M.1
Salman, L.2
Sabag, O.3
Patel, M.S.4
Lorberboum-Galski, H.5
-
138
-
-
70349755717
-
Reversal of long-term dendritic spine alterations in Alzheimer disease models
-
Smith DL, Pozueta J, Gong B, Arancio O, Shelanski M. Reversal of long-term dendritic spine alterations in Alzheimer disease models. Proc Natl Acad Sci USA 2009; 106: 16877-82.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16877-16882
-
-
Smith, D.L.1
Pozueta, J.2
Gong, B.3
Arancio, O.4
Shelanski, M.5
-
139
-
-
50549103817
-
Transducible P11-CNTF rescues the learning and memory impairments induced by amyloid-beta peptide in mice
-
Qu HY, Zhang T, Li XL, et al. Transducible P11-CNTF rescues the learning and memory impairments induced by amyloid-beta peptide in mice. Eur J Pharmacol 2008; 594: 93-100.
-
(2008)
Eur J Pharmacol
, vol.594
, pp. 93-100
-
-
Qu, H.Y.1
Zhang, T.2
Li, X.L.3
-
140
-
-
4544348352
-
Alternative therapy of Alzheimer's disease via supplementation with choline acetyltransferase
-
Fu AL, Li Q, Dong ZH, Huang SJ, Wang YX, Sun MJ. Alternative therapy of Alzheimer's disease via supplementation with choline acetyltransferase. Neurosci Lett 2004; 368: 258-62.
-
(2004)
Neurosci Lett
, vol.368
, pp. 258-262
-
-
Fu, A.L.1
Li, Q.2
Dong, Z.H.3
Huang, S.J.4
Wang, Y.X.5
Sun, M.J.6
-
141
-
-
34248233685
-
In vivo monitoring the fate of Cy5.5-Tat labeled T lymphocytes by quantitative nearinfrared fluorescence imaging during acute brain inflammation in a rat model of experimental autoimmune encephalomyelitis
-
Berger C, Gremlich HU, Schmidt P, et al. In vivo monitoring the fate of Cy5.5-Tat labeled T lymphocytes by quantitative nearinfrared fluorescence imaging during acute brain inflammation in a rat model of experimental autoimmune encephalomyelitis. J Immunol Methods 2007; 323: 65-77.
-
(2007)
J Immunol Methods
, vol.323
, pp. 65-77
-
-
Berger, C.1
Gremlich, H.U.2
Schmidt, P.3
-
142
-
-
13644251480
-
Synthesis of water-dispersible fluorescent, radio-opaque, and paramagnetic CdS:Mn/ZnS quantum dots: A multifunctional probe for bioimaging
-
Santra S, Yang H, Holloway PH, Stanley JT, Mericle RA. Synthesis of water-dispersible fluorescent, radio-opaque, and paramagnetic CdS:Mn/ZnS quantum dots: a multifunctional probe for bioimaging. J Am Chem Soc 2005; 127: 1656-7.
-
(2005)
J Am Chem Soc
, vol.127
, pp. 1656-1657
-
-
Santra, S.1
Yang, H.2
Holloway, P.H.3
Stanley, J.T.4
Mericle, R.A.5
-
143
-
-
11244308079
-
TAT conjugated, FITC doped silica nanoparticles for bioimaging applications
-
Santra S, Yang H, Dutta D, et al. TAT conjugated, FITC doped silica nanoparticles for bioimaging applications. Chem Commun (Camb) 2004: 2810-1.
-
(2004)
Chem Commun (Camb)
, pp. 2810-2811
-
-
Santra, S.1
Yang, H.2
Dutta, D.3
-
144
-
-
80053563934
-
Liposome formulated with TAT-modified cholesterol for enhancing the brain delivery
-
Qin Y, Chen H, Yuan W, et al. Liposome formulated with TAT-modified cholesterol for enhancing the brain delivery. Int J Pharm 2011; 419: 85-95.
-
(2011)
Int J Pharm
, vol.419
, pp. 85-95
-
-
Qin, Y.1
Chen, H.2
Yuan, W.3
-
145
-
-
80054735802
-
Cell-penetrating peptide-modified block copolymer micelles promote direct brain delivery via intranasal administration
-
Kanazawa T, Taki H, Tanaka K, Takashima Y, Okada H. Cell-penetrating peptide-modified block copolymer micelles promote direct brain delivery via intranasal administration. Pharm Res 2011; 28: 2130-9.
-
(2011)
Pharm Res
, vol.28
, pp. 2130-2139
-
-
Kanazawa, T.1
Taki, H.2
Tanaka, K.3
Takashima, Y.4
Okada, H.5
-
146
-
-
75149139976
-
The efficacy of self-assembled cationic antimicrobial peptide nanoparticles against Cryptococcus neoformans for the treatment of meningitis
-
Wang H, Xu K, Liu L, et al. The efficacy of self-assembled cationic antimicrobial peptide nanoparticles against Cryptococcus neoformans for the treatment of meningitis. Biomaterials 2010; 31: 2874-81.
-
(2010)
Biomaterials
, vol.31
, pp. 2874-2881
-
-
Wang, H.1
Xu, K.2
Liu, L.3
-
147
-
-
58149185965
-
Polymeric micelles anchored with TAT for delivery of antibiotics across the bloodbrain barrier
-
Liu L, Venkatraman SS, Yang YY, et al. Polymeric micelles anchored with TAT for delivery of antibiotics across the bloodbrain barrier. Biopolymers 2008; 90: 617-23.
-
(2008)
Biopolymers
, vol.90
, pp. 617-623
-
-
Liu, L.1
Venkatraman, S.S.2
Yang, Y.Y.3
-
148
-
-
38549180565
-
Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEGTAT for drug delivery across the blood-brain barrier
-
Liu L, Guo K, Lu J, et al. Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEGTAT for drug delivery across the blood-brain barrier. Biomaterials 2008; 29: 1509-17.
-
(2008)
Biomaterials
, vol.29
, pp. 1509-1517
-
-
Liu, L.1
Guo, K.2
Lu, J.3
-
149
-
-
50849094554
-
TAT-conjugated nanoparticles for the CNS delivery of anti-HIV drugs
-
Rao KS, Reddy MK, Horning JL, Labhasetwar V. TAT-conjugated nanoparticles for the CNS delivery of anti-HIV drugs. Biomaterials 2008; 29: 4429-38.
-
(2008)
Biomaterials
, vol.29
, pp. 4429-4438
-
-
Rao, K.S.1
Reddy, M.K.2
Horning, J.L.3
Labhasetwar, V.4
-
150
-
-
10344221003
-
Cellular uptake of argininerich peptides: Roles for macropinocytosis and actin rearrangement
-
Nakase I, Niwa M, Takeuchi T, et al. Cellular uptake of argininerich peptides: roles for macropinocytosis and actin rearrangement. Mol Ther 2004; 10: 1011-22.
-
(2004)
Mol Ther
, vol.10
, pp. 1011-1022
-
-
Nakase, I.1
Niwa, M.2
Takeuchi, T.3
-
151
-
-
79959236618
-
Expression in CHO cells and pharmacokinetics and brain uptake in the Rhesus monkey of an IgG-iduronate-2-sulfatase fusion protein
-
Lu JZ, Boado RJ, Hui EK, Zhou QH, Pardridge WM. Expression in CHO cells and pharmacokinetics and brain uptake in the Rhesus monkey of an IgG-iduronate-2-sulfatase fusion protein. Biotechnol Bioeng 2011; 108: 1954-64.
-
(2011)
Biotechnol Bioeng
, vol.108
, pp. 1954-1964
-
-
Lu, J.Z.1
Boado, R.J.2
Hui, E.K.3
Zhou, Q.H.4
Pardridge, W.M.5
-
152
-
-
74849088013
-
IgG-single chain Fv fusion protein therapeutic for Alzheimer's disease: Expression in CHO cells and pharmacokinetics and brain delivery in the rhesus monkey
-
Boado RJ, Lu JZ, Hui EK, Pardridge WM. IgG-single chain Fv fusion protein therapeutic for Alzheimer's disease: Expression in CHO cells and pharmacokinetics and brain delivery in the rhesus monkey. Biotechnol Bioeng; 105: 627-35.
-
Biotechnol Bioeng
, vol.105
, pp. 627-635
-
-
Boado, R.J.1
Lu, J.Z.2
Hui, E.K.3
Pardridge, W.M.4
-
153
-
-
0035937124
-
Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery
-
Futaki S, Suzuki T, Ohashi W, et al. Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery. J Biol Chem 2001; 276: 5836-40.
-
(2001)
J Biol Chem
, vol.276
, pp. 5836-5840
-
-
Futaki, S.1
Suzuki, T.2
Ohashi, W.3
-
154
-
-
0037119348
-
Efficiency of protein transduction is cell type-dependent and is enhanced by dextran sulfate
-
Mai JC, Shen H, Watkins SC, Cheng T, Robbins PD. Efficiency of protein transduction is cell type-dependent and is enhanced by dextran sulfate. J Biol Chem 2002; 277: 30208-18.
-
(2002)
J Biol Chem
, vol.277
, pp. 30208-30218
-
-
Mai, J.C.1
Shen, H.2
Watkins, S.C.3
Cheng, T.4
Robbins, P.D.5
-
155
-
-
0037169486
-
Possible existence of common internalization mechanisms among arginine-rich peptides
-
Suzuki T, Futaki S, Niwa M, Tanaka S, Ueda K, Sugiura Y. Possible existence of common internalization mechanisms among arginine-rich peptides. J Biol Chem 2002; 277: 2437-43.
-
(2002)
J Biol Chem
, vol.277
, pp. 2437-2443
-
-
Suzuki, T.1
Futaki, S.2
Niwa, M.3
Tanaka, S.4
Ueda, K.5
Sugiura, Y.6
-
156
-
-
0029982569
-
Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent
-
Derossi D, Calvet S, Trembleau A, Brunissen A, Chassaing G, Prochiantz A. Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent. J Biol Chem 1996; 271: 18188-93.
-
(1996)
J Biol Chem
, vol.271
, pp. 18188-18193
-
-
Derossi, D.1
Calvet, S.2
Trembleau, A.3
Brunissen, A.4
Chassaing, G.5
Prochiantz, A.6
-
157
-
-
9644291651
-
On the mechanism of non-endosomial peptide-mediated cellular delivery of nucleic acids
-
Deshayes S, Gerbal-Chaloin S, Morris MC, et al. On the mechanism of non-endosomial peptide-mediated cellular delivery of nucleic acids. Biochim Biophys Acta 2004; 1667: 141-7.
-
(2004)
Biochim Biophys Acta
, vol.1667
, pp. 141-147
-
-
Deshayes, S.1
Gerbal-Chaloin, S.2
Morris, M.C.3
-
158
-
-
0033948268
-
Messenger proteins: Homeoproteins, TAT and others
-
Prochiantz A. Messenger proteins: homeoproteins, TAT and others. Curr Opin Cell Biol 2000; 12: 400-6.
-
(2000)
Curr Opin Cell Biol
, vol.12
, pp. 400-406
-
-
Prochiantz, A.1
-
159
-
-
38049156027
-
Molecular dynamics simulations suggest a mechanism for translocation of the HIV-1 TAT peptide across lipid membranes
-
Herce HD, Garcia AE. Molecular dynamics simulations suggest a mechanism for translocation of the HIV-1 TAT peptide across lipid membranes. Proc Natl Acad Sci USA 2007; 104: 20805-10.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20805-20810
-
-
Herce, H.D.1
Garcia, A.E.2
-
160
-
-
63649127300
-
Cell entry of arginine-rich peptides is independent of endocytosis
-
Ter-Avetisyan G, Tunnemann G, Nowak D, et al. Cell entry of arginine-rich peptides is independent of endocytosis. J Biol Chem 2009; 284: 3370-8.
-
(2009)
J Biol Chem
, vol.284
, pp. 3370-3378
-
-
Ter-Avetisyan, G.1
Tunnemann, G.2
Nowak, D.3
-
161
-
-
0141446039
-
Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins
-
Fittipaldi A, Ferrari A, Zoppe M, et al. Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins. J Biol Chem 2003; 278: 34141-9.
-
(2003)
J Biol Chem
, vol.278
, pp. 34141-34149
-
-
Fittipaldi, A.1
Ferrari, A.2
Zoppe, M.3
-
162
-
-
17644386231
-
Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors
-
Richard JP, Melikov K, Brooks H, Prevot P, Lebleu B, Chernomordik LV. Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors. J Biol Chem 2005; 280: 15300-6.
-
(2005)
J Biol Chem
, vol.280
, pp. 15300-15306
-
-
Richard, J.P.1
Melikov, K.2
Brooks, H.3
Prevot, P.4
Lebleu, B.5
Chernomordik, L.V.6
-
163
-
-
2342595835
-
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
-
Wadia JS, Stan RV, Dowdy SF. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med 2004; 10: 310-5.
-
(2004)
Nat Med
, vol.10
, pp. 310-315
-
-
Wadia, J.S.1
Stan, R.V.2
Dowdy, S.F.3
-
164
-
-
11844268027
-
Cationic TAT peptide transduction domain enters cells by macropinocytosis
-
Kaplan IM, Wadia JS, Dowdy SF. Cationic TAT peptide transduction domain enters cells by macropinocytosis. J Control Release 2005; 102: 247-53.
-
(2005)
J Control Release
, vol.102
, pp. 247-253
-
-
Kaplan, I.M.1
Wadia, J.S.2
Dowdy, S.F.3
-
165
-
-
33645640345
-
High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression
-
Khalil IA, Kogure K, Futaki S, Harashima H. High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression. J Biol Chem 2006; 281: 3544-51.
-
(2006)
J Biol Chem
, vol.281
, pp. 3544-3551
-
-
Khalil, I.A.1
Kogure, K.2
Futaki, S.3
Harashima, H.4
-
166
-
-
9244255342
-
Protein cargo delivery properties of cell-penetrating peptides. A comparative study
-
Saalik P, Elmquist A, Hansen M, et al. Protein cargo delivery properties of cell-penetrating peptides. A comparative study. Bioconjug Chem 2004; 15: 1246-53.
-
(2004)
Bioconjug Chem
, vol.15
, pp. 1246-1253
-
-
Saalik, P.1
Elmquist, A.2
Hansen, M.3
-
167
-
-
0024445852
-
Transfer of monoclonal antibodies into mammalian cells by electroporation
-
Chakrabarti R, Wylie DE, Schuster SM. Transfer of monoclonal antibodies into mammalian cells by electroporation. J Biol Chem 1989; 264: 15494-500.
-
(1989)
J Biol Chem
, vol.264
, pp. 15494-15500
-
-
Chakrabarti, R.1
Wylie, D.E.2
Schuster, S.M.3
-
168
-
-
0024007966
-
Antiviral state against influenza virus neutralized by microinjection of antibodies to interferon-induced Mx proteins
-
Arnheiter H, Haller O. Antiviral state against influenza virus neutralized by microinjection of antibodies to interferon-induced Mx proteins. Embo J 1988; 7: 1315-20.
-
(1988)
Embo J
, vol.7
, pp. 1315-1320
-
-
Arnheiter, H.1
Haller, O.2
-
169
-
-
79959190803
-
A HA2-Fusion tag limits the endosomal release of its protein cargo despite causing endosomal lysis
-
Lee YJ, Johnson G, Peltier GC, Pellois JP. A HA2-Fusion tag limits the endosomal release of its protein cargo despite causing endosomal lysis. Biochim Biophys Acta 2011; 1810: 752-8.
-
(2011)
Biochim Biophys Acta
, vol.1810
, pp. 752-758
-
-
Lee, Y.J.1
Johnson, G.2
Peltier, G.C.3
Pellois, J.P.4
-
170
-
-
0031984072
-
Trojan peptides: The penetratin system for intracellular delivery
-
Derossi D, Chassaing G, Prochiantz A. Trojan peptides: the penetratin system for intracellular delivery. Trends Cell Biol 1998; 8: 84-7.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 84-87
-
-
Derossi, D.1
Chassaing, G.2
Prochiantz, A.3
-
171
-
-
79952513839
-
Inverted micelle formation of cell-penetrating peptide studied by coarse-grained simulation: Importance of attractive force between cell-penetrating peptides and lipid head group
-
Kawamoto S, Takasu M, Miyakawa T, et al. Inverted micelle formation of cell-penetrating peptide studied by coarse-grained simulation: importance of attractive force between cell-penetrating peptides and lipid head group. J Chem Phys 2011; 134: 095103.
-
(2011)
J Chem Phys
, vol.134
, pp. 095103
-
-
Kawamoto, S.1
Takasu, M.2
Miyakawa, T.3
-
172
-
-
0037592877
-
Insight into the mechanism of the peptide-based gene delivery system MPG: Implications for delivery of siRNA into mammalian cells
-
Simeoni F, Morris MC, Heitz F, Divita G. Insight into the mechanism of the peptide-based gene delivery system MPG: implications for delivery of siRNA into mammalian cells. Nucleic Acids Res 2003; 31: 2717-24.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 2717-2724
-
-
Simeoni, F.1
Morris, M.C.2
Heitz, F.3
Divita, G.4
-
173
-
-
79955128744
-
Nuclear targeted delivery of macromolecules to retina and cornea
-
Binder C, Read SP, Cashman SM, Kumar-Singh R. Nuclear targeted delivery of macromolecules to retina and cornea. J Gene Med 2011; 13: 158-70.
-
(2011)
J Gene Med
, vol.13
, pp. 158-170
-
-
Binder, C.1
Read, S.P.2
Cashman, S.M.3
Kumar-Singh, R.4
-
174
-
-
0038730828
-
A novel TAT-mitochondrial signal sequence fusion protein is processed, stays in mitochondria, and crosses the placenta
-
Del Gaizo V, Payne RM. A novel TAT-mitochondrial signal sequence fusion protein is processed, stays in mitochondria, and crosses the placenta. Mol Ther 2003; 7: 720-30.
-
(2003)
Mol Ther
, vol.7
, pp. 720-730
-
-
Del Gaizo, V.1
Payne, R.M.2
-
175
-
-
41949083981
-
Mitochondria-penetrating peptides
-
Horton KL, Stewart KM, Fonseca SB, Guo Q, Kelley SO. Mitochondria-penetrating peptides. Chem Biol 2008; 15: 375-82.
-
(2008)
Chem Biol
, vol.15
, pp. 375-382
-
-
Horton, K.L.1
Stewart, K.M.2
Fonseca, S.B.3
Guo, Q.4
Kelley, S.O.5
-
176
-
-
27744516094
-
Mitochondria-targeted peptide prevents mitochondrial depolarization and apoptosis induced by tert-butyl hydroperoxide in neuronal cell lines
-
Zhao K, Luo G, Giannelli S, Szeto HH. Mitochondria-targeted peptide prevents mitochondrial depolarization and apoptosis induced by tert-butyl hydroperoxide in neuronal cell lines. Biochem Pharmacol 2005; 70: 1796-806.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 1796-1806
-
-
Zhao, K.1
Luo, G.2
Giannelli, S.3
Szeto, H.H.4
-
177
-
-
80054088405
-
Low molecular weight protaminefunctionalized nanoparticles for drug delivery to the brain after intranasal administration
-
Xia H, Gao X, Gu G, L et al. Low molecular weight protaminefunctionalized nanoparticles for drug delivery to the brain after intranasal administration. Biomaterials 2011; 32: 9888-98.
-
(2011)
Biomaterials
, vol.32
, pp. 9888-9898
-
-
Xia, H.1
Gao, X.2
Gu, G.L.3
-
178
-
-
58149461144
-
Gene delivery into ischemic myocardium by double-targeted lipoplexes with antimyosin antibody and TAT peptide
-
Ko YT, Hartner WC, Kale A, Torchilin VP. Gene delivery into ischemic myocardium by double-targeted lipoplexes with antimyosin antibody and TAT peptide. Gene Ther 2009; 16: 52-9.
-
(2009)
Gene Ther
, vol.16
, pp. 52-59
-
-
Ko, Y.T.1
Hartner, W.C.2
Kale, A.3
Torchilin, V.P.4
-
179
-
-
0031759170
-
Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration
-
Nagahara H, Vocero-Akbani AM, Snyder EL, et al. Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration. Nat Med 1998; 4: 1449-52.
-
(1998)
Nat Med
, vol.4
, pp. 1449-1452
-
-
Nagahara, H.1
Vocero-Akbani, A.M.2
Snyder, E.L.3
-
180
-
-
33846591495
-
The taming of the cell penetrating domain of the HIV Tat: Myths and realities
-
Chauhan A, Tikoo A, Kapur AK, Singh M. The taming of the cell penetrating domain of the HIV Tat: myths and realities. J Control Release 2007; 117: 148-62.
-
(2007)
J Control Release
, vol.117
, pp. 148-162
-
-
Chauhan, A.1
Tikoo, A.2
Kapur, A.K.3
Singh, M.4
-
181
-
-
70349087365
-
TAT peptide and its conjugates: Proteolytic stability
-
Grunwald J, Rejtar T, Sawant R, Wang Z, Torchilin VP. TAT peptide and its conjugates: proteolytic stability. Bioconjug Chem 2009; 20: 1531-7.
-
(2009)
Bioconjug Chem
, vol.20
, pp. 1531-1537
-
-
Grunwald, J.1
Rejtar, T.2
Sawant, R.3
Wang, Z.4
Torchilin, V.P.5
-
182
-
-
47049117723
-
D-SAP: A new, noncytotoxic, and fully protease resistant cell-penetrating peptide
-
Pujals S, Fernandez-Carneado J, Ludevid MD, Giralt E. D-SAP: a new, noncytotoxic, and fully protease resistant cell-penetrating peptide. ChemMedChem 2008; 3: 296-301.
-
(2008)
ChemMedChem
, vol.3
, pp. 296-301
-
-
Pujals, S.1
Fernandez-Carneado, J.2
Ludevid, M.D.3
Giralt, E.4
-
183
-
-
0038155175
-
Novel bioactive and stable neurotensin peptide analogues capable of delivering radiopharmaceuticals and molecular beacons to tumors
-
Achilefu S, Srinivasan A, Schmidt MA, Jimenez HN, Bugaj JE, Erion JL. Novel bioactive and stable neurotensin peptide analogues capable of delivering radiopharmaceuticals and molecular beacons to tumors. J Med Chem 2003; 46: 3403-11.
-
(2003)
J Med Chem
, vol.46
, pp. 3403-3411
-
-
Achilefu, S.1
Srinivasan, A.2
Schmidt, M.A.3
Jimenez, H.N.4
Bugaj, J.E.5
Erion, J.L.6
-
184
-
-
37849047198
-
Antimicrobial activity and protease stability of peptides containing fluorinated amino acids
-
Meng H, Kumar K. Antimicrobial activity and protease stability of peptides containing fluorinated amino acids. J Am Chem Soc 2007; 129: 15615-22.
-
(2007)
J Am Chem Soc
, vol.129
, pp. 15615-15622
-
-
Meng, H.1
Kumar, K.2
-
185
-
-
71749110589
-
Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling
-
Kilk K, Mahlapuu R, Soomets U, Langel U. Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling. Toxicology 2009; 265: 87-95.
-
(2009)
Toxicology
, vol.265
, pp. 87-95
-
-
Kilk, K.1
Mahlapuu, R.2
Soomets, U.3
Langel, U.4
-
186
-
-
34548498615
-
Cell-permeable peptides induce dose-and length-dependent cytotoxic effects
-
Cardozo AK, Buchillier V, Mathieu M, et al. Cell-permeable peptides induce dose-and length-dependent cytotoxic effects. Biochim Biophys Acta 2007; 1768: 2222-34.
-
(2007)
Biochim Biophys Acta
, vol.1768
, pp. 2222-2234
-
-
Cardozo, A.K.1
Buchillier, V.2
Mathieu, M.3
-
187
-
-
35048856889
-
Cargodependent cytotoxicity and delivery efficacy of cell-penetrating peptides: A comparative study
-
El-Andaloussi S, Jarver P, Johansson HJ, Langel U. Cargodependent cytotoxicity and delivery efficacy of cell-penetrating peptides: a comparative study. Biochem J 2007; 407: 285-92.
-
(2007)
Biochem J
, vol.407
, pp. 285-292
-
-
El-Andaloussi, S.1
Jarver, P.2
Johansson, H.J.3
Langel, U.4
-
188
-
-
57149110011
-
CNS delivery via adsorptive transcytosis
-
Herve F, Ghinea N, Scherrmann JM. CNS delivery via adsorptive transcytosis. Aaps J 2008; 10: 455-72.
-
(2008)
Aaps J
, vol.10
, pp. 455-472
-
-
Herve, F.1
Ghinea, N.2
Scherrmann, J.M.3
|