Modified Tat peptide with cationic lipids enhances gene transfection efficiency via temperature-dependent and caveolae-mediated endocytosis

Journal of Controlled Release

Volumn 152, Issue 2, 2011, Pages 278-285

  Yamano, Seiichi ^a   Dai, Jisen ^a   Yuvienco, Carlo ^b   Khapli, Sachin ^b   Moursi, Amr M ^a   Montclare, Jin K ^b  

^a NEW YORK UNIVERSITY   (United States)

^b POLYTECHNIC UNIVERSITY   (United States)

Author keywords

Gene delivery; Lipids; Plasmid DNA; Tat peptide; Transfection

Indexed keywords

CATIONIC LIPIDS; CELL LINES; CELL TYPES; CYSTEINE RESIDUES; DNA DELIVERY; ENERGY DEPENDENT; GENE DELIVERY; GENE TRANSFECTION; GENE VECTORS; HIV-1 TAT; INTRACELLULAR GENE DELIVERY; LIPID SYSTEMS; LOW TEMPERATURES; LUCIFERASE EXPRESSION; NONVIRAL; PLASMID DNA; TAT PEPTIDE; TEMPERATURE DEPENDENT; TRANSFECTION; TRANSFECTION EFFICIENCY;

AMINO ACIDS; CELL CULTURE; DNA; DRUG THERAPY; GENE THERAPY; GENE TRANSFER; LIPIDS; PEPTIDES; ZETA POTENTIAL;

MOLECULAR BIOLOGY;

CHLOROQUINE; CHLORPROMAZINE; CYSTEINE; FILIPIN; HISTIDINE; LIPID; LUCIFERASE; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; CAVEOLA; CONTROLLED STUDY; DNA PROTEIN COMPLEX; ENDOCYTOSIS; GENE DELIVERY SYSTEM; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; ZETA POTENTIAL;

3T3 CELLS; ANIMALS; CATIONS; CAVEOLAE; CELL LINE; CELL SURVIVAL; CLATHRIN; DNA; ENDOCYTOSIS; HUMANS; LIPID METABOLISM; LIPIDS; MICE; PEPTIDE FRAGMENTS; PLASMIDS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TRANSFECTION;

EID: 79958265908     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.02.004     Document Type: Article

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