-
1
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
-
Bennett B.L., Sasaki D.T., Murray B.W., O'Leary E.C., Sakata S.T., Xu W., Leisten J.C., Motiwala A., Pierce S., Satoh Y., Bhagwat S.S., Manning A.M., and Anderson D.W. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci U S A 98 (2001) 13681-13686
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13681-13686
-
-
Bennett, B.L.1
Sasaki, D.T.2
Murray, B.W.3
O'Leary, E.C.4
Sakata, S.T.5
Xu, W.6
Leisten, J.C.7
Motiwala, A.8
Pierce, S.9
Satoh, Y.10
Bhagwat, S.S.11
Manning, A.M.12
Anderson, D.W.13
-
2
-
-
0035152487
-
Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death
-
Bonny C., Oberson A., Negri S., Sauser C., and Schorderet D.F. Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death. Diabetes 50 (2001) 77-82
-
(2001)
Diabetes
, vol.50
, pp. 77-82
-
-
Bonny, C.1
Oberson, A.2
Negri, S.3
Sauser, C.4
Schorderet, D.F.5
-
3
-
-
2342573044
-
Use of cell-permeable peptides to prevent neuronal degeneration
-
Borsello T., and Bonny C. Use of cell-permeable peptides to prevent neuronal degeneration. Trends Mol Med 10 (2004) 239-244
-
(2004)
Trends Mol Med
, vol.10
, pp. 239-244
-
-
Borsello, T.1
Bonny, C.2
-
4
-
-
0141724805
-
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia
-
Borsello T., Clarke P.G., Hirt L., Vercelli A., Repici M., Schorderet D.F., Bogousslavsky J., and Bonny C. A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia. Nat Med 9 (2003) 1180-1186
-
(2003)
Nat Med
, vol.9
, pp. 1180-1186
-
-
Borsello, T.1
Clarke, P.G.2
Hirt, L.3
Vercelli, A.4
Repici, M.5
Schorderet, D.F.6
Bogousslavsky, J.7
Bonny, C.8
-
5
-
-
0042380209
-
N-methyl-d-aspartate-triggered neuronal death in organotypic hippocampal cultures is endocytic, autophagic and mediated by the c-Jun N-terminal kinase pathway
-
Borsello T., Croquelois K., Hornung J.P., and Clarke P.G. N-methyl-d-aspartate-triggered neuronal death in organotypic hippocampal cultures is endocytic, autophagic and mediated by the c-Jun N-terminal kinase pathway. Eur J Neurosci 18 (2003) 473-485
-
(2003)
Eur J Neurosci
, vol.18
, pp. 473-485
-
-
Borsello, T.1
Croquelois, K.2
Hornung, J.P.3
Clarke, P.G.4
-
6
-
-
13444301318
-
Specific pathophysiological functions of JNK isoforms in the brain
-
Brecht S., Kirchhof R., Chromik A., Willesen M., Nicolaus T., Raivich G., Wessig J., Waetzig V., Goetz M., Claussen M., Pearse D., Kuan C.Y., Vaudano E., Behrens A., Wagner E., Flavell R.A., Davis R.J., and Herdegen T. Specific pathophysiological functions of JNK isoforms in the brain. Eur J Neurosci 21 (2005) 363-377
-
(2005)
Eur J Neurosci
, vol.21
, pp. 363-377
-
-
Brecht, S.1
Kirchhof, R.2
Chromik, A.3
Willesen, M.4
Nicolaus, T.5
Raivich, G.6
Wessig, J.7
Waetzig, V.8
Goetz, M.9
Claussen, M.10
Pearse, D.11
Kuan, C.Y.12
Vaudano, E.13
Behrens, A.14
Wagner, E.15
Flavell, R.A.16
Davis, R.J.17
Herdegen, T.18
-
7
-
-
14844333103
-
Control of death receptor and mitochondrial-dependent apoptosis by c-Jun N-terminal kinase in hippocampal CA1 neurones following global transient ischaemia
-
Carboni S., Antonsson B., Gaillard P., Gotteland J.P., Gillon J.Y., and Vitte P.A. Control of death receptor and mitochondrial-dependent apoptosis by c-Jun N-terminal kinase in hippocampal CA1 neurones following global transient ischaemia. J Neurochem 92 (2005) 1054-1060
-
(2005)
J Neurochem
, vol.92
, pp. 1054-1060
-
-
Carboni, S.1
Antonsson, B.2
Gaillard, P.3
Gotteland, J.P.4
Gillon, J.Y.5
Vitte, P.A.6
-
8
-
-
33846202874
-
Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons
-
Centeno C., Repici M., Chatton J.Y., Riederer B.M., Bonny C., Nicod P., Price M., Clarke P.G., Papa S., Franzoso G., and Borsello T. Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons. Cell Death Differ 14 (2007) 240-253
-
(2007)
Cell Death Differ
, vol.14
, pp. 240-253
-
-
Centeno, C.1
Repici, M.2
Chatton, J.Y.3
Riederer, B.M.4
Bonny, C.5
Nicod, P.6
Price, M.7
Clarke, P.G.8
Papa, S.9
Franzoso, G.10
Borsello, T.11
-
9
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
Chang L., and Karin M. Mammalian MAP kinase signalling cascades. Nature 410 (2001) 37-40
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
10
-
-
0034667705
-
Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons
-
Coffey E.T., Hongisto V., Dickens M., Davis R.J., and Courtney M.J. Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons. J Neurosci 20 (2000) 7602-7613
-
(2000)
J Neurosci
, vol.20
, pp. 7602-7613
-
-
Coffey, E.T.1
Hongisto, V.2
Dickens, M.3
Davis, R.J.4
Courtney, M.J.5
-
11
-
-
5644276383
-
Delivery of bioactive molecules into the cell: the Trojan horse approach
-
Dietz G.P., and Bahr M. Delivery of bioactive molecules into the cell: the Trojan horse approach. Mol Cell Neurosci 27 (2004) 85-131
-
(2004)
Mol Cell Neurosci
, vol.27
, pp. 85-131
-
-
Dietz, G.P.1
Bahr, M.2
-
12
-
-
28144440865
-
Peptide-enhanced cellular internalization of proteins in neuroscience
-
Dietz G.P., and Bahr M. Peptide-enhanced cellular internalization of proteins in neuroscience. Brain Res Bull 68 (2005) 103-114
-
(2005)
Brain Res Bull
, vol.68
, pp. 103-114
-
-
Dietz, G.P.1
Bahr, M.2
-
13
-
-
18944381512
-
Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway
-
Gao Y., Signore A.P., Yin W., Cao G., Yin X.M., Sun F., Luo Y., Graham S.H., and Chen J. Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway. J Cereb Blood Flow Metab 25 (2005) 694-712
-
(2005)
J Cereb Blood Flow Metab
, vol.25
, pp. 694-712
-
-
Gao, Y.1
Signore, A.P.2
Yin, W.3
Cao, G.4
Yin, X.M.5
Sun, F.6
Luo, Y.7
Graham, S.H.8
Chen, J.9
-
14
-
-
4744355139
-
c-Jun N-terminal kinases (JNKs) and the cytoskeleton-functions beyond neurodegeneration
-
Gelderblom M., Eminel S., Herdegen T., and Waetzig V. c-Jun N-terminal kinases (JNKs) and the cytoskeleton-functions beyond neurodegeneration. Int J Dev Neurosci 22 (2004) 559-564
-
(2004)
Int J Dev Neurosci
, vol.22
, pp. 559-564
-
-
Gelderblom, M.1
Eminel, S.2
Herdegen, T.3
Waetzig, V.4
-
15
-
-
0025483799
-
Neuron imaging with Neurolucida-a PC-based system for image combining microscopy
-
Glaser J.R., and Glaser E.M. Neuron imaging with Neurolucida-a PC-based system for image combining microscopy. Comput Med Imaging Graph 14 (1990) 307-317
-
(1990)
Comput Med Imaging Graph
, vol.14
, pp. 307-317
-
-
Glaser, J.R.1
Glaser, E.M.2
-
16
-
-
33745150702
-
Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosis
-
Guan Q.H., Pei D.S., Liu X.M., Wang X.T., Xu T.L., and Zhang G.Y. Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosis. Brain Res 1092 (2006) 36-46
-
(2006)
Brain Res
, vol.1092
, pp. 36-46
-
-
Guan, Q.H.1
Pei, D.S.2
Liu, X.M.3
Wang, X.T.4
Xu, T.L.5
Zhang, G.Y.6
-
17
-
-
0031149046
-
The c-Jun transcription factor-bipotential mediator of neuronal death, survival and regeneration
-
Herdegen T., Skene P., and Bahr M. The c-Jun transcription factor-bipotential mediator of neuronal death, survival and regeneration. Trends Neurosci 20 (1997) 227-231
-
(1997)
Trends Neurosci
, vol.20
, pp. 227-231
-
-
Herdegen, T.1
Skene, P.2
Bahr, M.3
-
18
-
-
0036263403
-
Role of mitogen- and stress-activated kinases in ischemic injury
-
Irving E.A., and Bamford M. Role of mitogen- and stress-activated kinases in ischemic injury. J Cereb Blood Flow Metab 22 (2002) 631-647
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 631-647
-
-
Irving, E.A.1
Bamford, M.2
-
19
-
-
10744229507
-
A critical role of neural-specific JNK3 for ischemic apoptosis
-
Kuan C.Y., Whitmarsh A.J., Yang D.D., Liao G., Schloemer A.J., Dong C., Bao J., Banasiak K.J., Haddad G.G., Flavell R.A., Davis R.J., and Rakic P. A critical role of neural-specific JNK3 for ischemic apoptosis. Proc Natl Acad Sci U S A 100 (2003) 15184-15189
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15184-15189
-
-
Kuan, C.Y.1
Whitmarsh, A.J.2
Yang, D.D.3
Liao, G.4
Schloemer, A.J.5
Dong, C.6
Bao, J.7
Banasiak, K.J.8
Haddad, G.G.9
Flavell, R.A.10
Davis, R.J.11
Rakic, P.12
-
20
-
-
17444405537
-
Activated mitogen-activated protein kinase kinase 7 redistributes to the cytosol and binds to Jun N-terminal kinase-interacting protein 1 involving oxidative stress during early reperfusion in rat hippocampal CA1 region
-
Li C.H., Wang R.M., Zhang Q.G., and Zhang G.Y. Activated mitogen-activated protein kinase kinase 7 redistributes to the cytosol and binds to Jun N-terminal kinase-interacting protein 1 involving oxidative stress during early reperfusion in rat hippocampal CA1 region. J Neurochem 93 (2005) 290-298
-
(2005)
J Neurochem
, vol.93
, pp. 290-298
-
-
Li, C.H.1
Wang, R.M.2
Zhang, Q.G.3
Zhang, G.Y.4
-
21
-
-
0037230304
-
Activation of the JNK signaling pathway: breaking the brake on apoptosis
-
Lin A. Activation of the JNK signaling pathway: breaking the brake on apoptosis. Bioessays 25 (2003) 17-24
-
(2003)
Bioessays
, vol.25
, pp. 17-24
-
-
Lin, A.1
-
22
-
-
4544255383
-
The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemia
-
Okuno S., Saito A., Hayashi T., and Chan P.H. The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemia. J Neurosci 24 (2004) 7879-7887
-
(2004)
J Neurosci
, vol.24
, pp. 7879-7887
-
-
Okuno, S.1
Saito, A.2
Hayashi, T.3
Chan, P.H.4
-
23
-
-
12844273579
-
The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region
-
Pan J., Zhang Q.G., and Zhang G.Y. The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region. Neuroscience 131 (2005) 147-159
-
(2005)
Neuroscience
, vol.131
, pp. 147-159
-
-
Pan, J.1
Zhang, Q.G.2
Zhang, G.Y.3
-
24
-
-
34247503156
-
Deletion of the c-Jun N-terminal kinase 3 gene protects neonatal mice against cerebral hypoxic-ischaemic injury
-
Pirianov G., Brywe K.G., Mallard C., Edwards D., Flavell R.A., Hagberg H., and Mehmet H. Deletion of the c-Jun N-terminal kinase 3 gene protects neonatal mice against cerebral hypoxic-ischaemic injury. J Cereb Blood Flow Metab 27 (2007) 1022-1032
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 1022-1032
-
-
Pirianov, G.1
Brywe, K.G.2
Mallard, C.3
Edwards, D.4
Flavell, R.A.5
Hagberg, H.6
Mehmet, H.7
-
25
-
-
0037860975
-
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
-
Putcha G.V., Le S., Frank S., Besirli C.G., Clark K., Chu B., Alix S., Youle R.J., LaMarche A., Maroney A.C., and Johnson Jr. E.M. JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron 38 (2003) 899-914
-
(2003)
Neuron
, vol.38
, pp. 899-914
-
-
Putcha, G.V.1
Le, S.2
Frank, S.3
Besirli, C.G.4
Clark, K.5
Chu, B.6
Alix, S.7
Youle, R.J.8
LaMarche, A.9
Maroney, A.C.10
Johnson Jr., E.M.11
-
26
-
-
0031807548
-
A model of transient unilateral focal ischemia with reperfusion in the P7 neonatal rat: morphological changes indicative of apoptosis
-
discussion 1461
-
Renolleau S., Aggoun-Zouaoui D., Ben-Ari Y., and Charriaut-Marlangue C. A model of transient unilateral focal ischemia with reperfusion in the P7 neonatal rat: morphological changes indicative of apoptosis. Stroke 29 (1998) 1454-1460 discussion 1461
-
(1998)
Stroke
, vol.29
, pp. 1454-1460
-
-
Renolleau, S.1
Aggoun-Zouaoui, D.2
Ben-Ari, Y.3
Charriaut-Marlangue, C.4
-
27
-
-
84934437038
-
JNK pathway as therapeutic target to prevent degeneration in the central nervous system
-
Repici M., and Borsello T. JNK pathway as therapeutic target to prevent degeneration in the central nervous system. Adv Exp Med Biol 588 (2006) 145-155
-
(2006)
Adv Exp Med Biol
, vol.588
, pp. 145-155
-
-
Repici, M.1
Borsello, T.2
-
28
-
-
0036988312
-
Discovery of CEP-1347/KT-7515, an inhibitor of the JNK/SAPK pathway for the treatment of neurodegenerative diseases
-
Saporito M.S., Hudkins R.L., and Maroney A.C. Discovery of CEP-1347/KT-7515, an inhibitor of the JNK/SAPK pathway for the treatment of neurodegenerative diseases. Prog Med Chem 40 (2002) 23-62
-
(2002)
Prog Med Chem
, vol.40
, pp. 23-62
-
-
Saporito, M.S.1
Hudkins, R.L.2
Maroney, A.C.3
-
29
-
-
28244484062
-
Enhanced targeting and killing of tumor cells expressing the CXC chemokine receptor 4 by transducible anticancer peptides
-
Snyder E.L., Saenz C.C., Denicourt C., Meade B.R., Cui X.S., Kaplan I.M., and Dowdy S.F. Enhanced targeting and killing of tumor cells expressing the CXC chemokine receptor 4 by transducible anticancer peptides. Cancer Res 65 (2005) 10646-10650
-
(2005)
Cancer Res
, vol.65
, pp. 10646-10650
-
-
Snyder, E.L.1
Saenz, C.C.2
Denicourt, C.3
Meade, B.R.4
Cui, X.S.5
Kaplan, I.M.6
Dowdy, S.F.7
-
30
-
-
33751046528
-
A signaling network for patterning of neuronal connectivity in the drosophila brain
-
Srahna M., Leyssen M., Choi C.M., Fradkin L.G., Noordermeer J.N., and Hassan B.A. A signaling network for patterning of neuronal connectivity in the drosophila brain. PLoS Biol 4 (2006) e348
-
(2006)
PLoS Biol
, vol.4
-
-
Srahna, M.1
Leyssen, M.2
Choi, C.M.3
Fradkin, L.G.4
Noordermeer, J.N.5
Hassan, B.A.6
-
31
-
-
0038576896
-
Immunohistochemical assessment of the glial mitogen-activated protein kinase activation in glaucoma
-
Tezel G., Chauhan B.C., LeBlanc R.P., and Wax M.B. Immunohistochemical assessment of the glial mitogen-activated protein kinase activation in glaucoma. Invest Ophthalmol Vis Sci 44 (2003) 3025-3033
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 3025-3033
-
-
Tezel, G.1
Chauhan, B.C.2
LeBlanc, R.P.3
Wax, M.B.4
-
32
-
-
28444461040
-
Present and future of cell-penetrating peptide mediated delivery systems: "is the Trojan horse too wild to go only to Troy?
-
Vives E. Present and future of cell-penetrating peptide mediated delivery systems: "is the Trojan horse too wild to go only to Troy?. " J Control Release 109 (2005) 77-85
-
(2005)
" J Control Release
, vol.109
, pp. 77-85
-
-
Vives, E.1
-
33
-
-
0141457877
-
A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss
-
Wang J., Van De Water T.R., Bonny C., de Ribaupierre F., Puel J.L., and Zine A. A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss. J Neurosci 23 (2003) 8596-8607
-
(2003)
J Neurosci
, vol.23
, pp. 8596-8607
-
-
Wang, J.1
Van De Water, T.R.2
Bonny, C.3
de Ribaupierre, F.4
Puel, J.L.5
Zine, A.6
-
34
-
-
0030815758
-
Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli
-
Xu X., Raber J., Yang D., Su B., and Mucke L. Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli. Proc Natl Acad Sci U S A 94 (1997) 12655-12660
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 12655-12660
-
-
Xu, X.1
Raber, J.2
Yang, D.3
Su, B.4
Mucke, L.5
-
35
-
-
0344013490
-
Cellular and molecular events underlying ischemia-induced neuronal apoptosis
-
Zheng Z., Zhao H., Steinberg G.K., and Yenari M.A. Cellular and molecular events underlying ischemia-induced neuronal apoptosis. Drug News Perspect 16 (2003) 497-503
-
(2003)
Drug News Perspect
, vol.16
, pp. 497-503
-
-
Zheng, Z.1
Zhao, H.2
Steinberg, G.K.3
Yenari, M.A.4
|