메뉴 건너뛰기




Volumn 68, Issue 7, 2009, Pages 823-831

Neuroprotection after status epilepticus by targeting protein interactions with postsynaptic density protein 95

Author keywords

Epilepsy; N methyl D aspartate receptor; Neuroprotection; Pilocarpine; Status epilepticus.

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEURON SPECIFIC NUCLEAR PROTEIN; NEUROPROTECTIVE AGENT; PILOCARPINE; POSTSYNAPTIC DENSITY PROTEIN 95; TAT N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B 9C; UNCLASSIFIED DRUG; DLGH4 PROTEIN, RAT; HYBRID PROTEIN; MEMBRANE PROTEIN; NERVE PROTEIN; PEPTIDE; SIGNAL PEPTIDE; TAT NR2B9C; TAT-NR2B9C;

EID: 68249157084     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/NEN.0b013e3181ac6b70     Document Type: Article
Times cited : (18)

References (77)
  • 1
    • 70349145131 scopus 로고    scopus 로고
    • A perspective, population-based epidemiologic study of status epilepticus in richmond, virginia
    • DeLorenzo RJ, Hauser WA, Towne AR, et al. A perspective, population-based epidemiologic study of status epilepticus in Richmond, Virginia. Neurology 1996;28:10-17
    • (1996) Neurology , vol.28 , pp. 10-17
    • Delorenzo, R.J.1    Hauser, W.A.2    Towne, A.R.3
  • 2
    • 0034090094 scopus 로고    scopus 로고
    • Status epilepticus: Risk factors and complications
    • Fountain NB. Status epilepticus: Risk factors and complications. Epilepsia 2000;41:23-30
    • (2000) Epilepsia , vol.41 , pp. 23-30
    • Fountain, N.B.1
  • 3
    • 0031738370 scopus 로고    scopus 로고
    • Status epilepticus causes long-term NMDA receptor-dependent behavioral changes and cognitive deficits
    • Rice AC, Floyd CL, Lyeth DG, et al. Status epilepticus causes long-term NMDA receptor-dependent behavioral changes and cognitive deficits. Epilepsia 1998;39:1148-57
    • (1998) Epilepsia , vol.39 , pp. 1148-1157
    • Rice, A.C.1    Floyd, C.L.2    Lyeth, D.G.3
  • 4
    • 39649085329 scopus 로고    scopus 로고
    • Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: Role of NMDA receptor activation and NMDA dependent calcium entry
    • Deshpande LS, Lou JK, Mian A, et al. Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: Role of NMDA receptor activation and NMDA dependent calcium entry. Eur J Pharmacol 2008;1:73-83
    • (2008) Eur J Pharmacol , vol.1 , pp. 73-83
    • Deshpande, L.S.1    Lou, J.K.2    Mian, A.3
  • 5
    • 0033898768 scopus 로고    scopus 로고
    • Status epilepticus-induced neuronal loss in humans without systemic complications or epilepsy.
    • Fujikawa DG, Itabashi HH, Wu A, et al. Status epilepticus-induced neuronal loss in humans without systemic complications or epilepsy. Epilepsia 2000;41:981-91
    • (2000) Epilepsia , vol.41 , pp. 981-991
    • Fujikawa, D.G.1    Itabashi, H.H.2    Wu, A.3
  • 6
    • 0024988456 scopus 로고
    • Progressive neuronal loss induced by kindling: A possible mechanism for mossy fiber synaptic reorganization and hippo-campal sclerosis
    • Cavazos JE, Sutula TP. Progressive neuronal loss induced by kindling: a possible mechanism for mossy fiber synaptic reorganization and hippo-campal sclerosis. Brain Res 1990;527:1-6
    • (1990) Brain Res , vol.527 , pp. 1-6
    • Cavazos, J.E.1    Sutula, T.P.2
  • 7
    • 0021838038 scopus 로고
    • Status epilepticus in well oxygenated rats causes neuronal necrosis
    • Nevander G, Ingvar M, Auer R, et al. Status epilepticus in well oxygenated rats causes neuronal necrosis. Ann Neurol 1985;18:281-90
    • (1985) Ann Neurol , vol.18 , pp. 281-290
    • Nevander, G.1    Ingvar, M.2    Auer, R.3
  • 8
    • 0023473194 scopus 로고
    • The susceptibility of rats to pilocarpine-induced seizures is age-dependent
    • Cavalheiro EA, Silva DF, Turski WA, et al. The susceptibility of rats to pilocarpine-induced seizures is age-dependent. Brain Res 1987;37:43-58
    • (1987) Brain Res , vol.37 , pp. 43-58
    • Cavalheiro, E.A.1    Silva, D.F.2    Turski, W.A.3
  • 9
    • 0021020387 scopus 로고
    • Cholinomimetics produce seizures and brain damage in rats
    • Turski WA, Czuczwar SJ, Kleinrok Z, et al. Cholinomimetics produce seizures and brain damage in rats. Experientia 1983;39:1408-11 (Pubitemid 14203754)
    • (1983) Experientia , vol.39 , Issue.12 , pp. 1408-1411
    • Turski, W.A.1    Czuczwar, S.J.2    Kleinrok, Z.3    Turski, L.4
  • 10
    • 0020545095 scopus 로고
    • Limbic seizures produced by pilocarpine in rats: Behavioural, electroencephalographic and neuro-pathological study
    • Turski WA, Cavalheiro EA, Schwarz M, et al. Limbic seizures produced by pilocarpine in rats: Behavioural, electroencephalographic and neuro-pathological study. Behav Brain Res 1983;9:315-35
    • (1983) Behav Brain Res , vol.9 , pp. 315-335
    • Turski, W.A.1    Cavalheiro, E.A.2    Schwarz, M.3
  • 11
    • 0021921141 scopus 로고
    • Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy
    • Ben-Ari Y. Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy. Neuroscience 1985;14:375-404
    • (1985) Neuroscience , vol.14 , pp. 375-404
    • Ben-Ari, Y.1
  • 12
    • 0034085349 scopus 로고    scopus 로고
    • Kainic acid-induced seizures produce necrotic, not apoptotic, neurons with internucleosomal DNA cleavage: Implications for programmed cell death mechanisms
    • Fujikawa DG, Shinmei SS, Cai B. Kainic acid-induced seizures produce necrotic, not apoptotic, neurons with internucleosomal DNA cleavage: implications for programmed cell death mechanisms. Neuroscience 2000;98:41-53
    • (2000) Neuroscience , vol.98 , pp. 41-53
    • Fujikawa, D.G.1    Shinmei, S.S.2    Cai, B.3
  • 13
    • 0025368487 scopus 로고
    • Ketamine, phencyclidine, and MK-801 protect against kainic acid-induced seizure-related brain damage
    • Clifford DB, Olney JW, Benz AM, et al. Ketamine, phencyclidine, and MK-801 protect against kainic acid-induced seizure-related brain damage. Epilepsia 1990;31:382-90
    • (1990) Epilepsia , vol.31 , pp. 382-390
    • Clifford, D.B.1    Olney, J.W.2    Benz, A.M.3
  • 14
    • 0024518639 scopus 로고
    • Potentiation of kainic acid epileptogenicity and sparing from neuronal damage by an NMDA receptor antagonist
    • Fariello RG, Golden GT, Smith GG, et al. Potentiation of kainic acid epileptogenicity and sparing from neuronal damage by an NMDA receptor antagonist. Epilepsy Res 1989;3:206-13
    • (1989) Epilepsy Res , vol.3 , pp. 206-213
    • Fariello, R.G.1    Golden, G.T.2    Smith, G.G.3
  • 15
    • 0028830749 scopus 로고
    • Neuroprotective effect of ketamine administered after status epilepticus onset
    • Fujikawa DG. Neuroprotective effect of ketamine administered after status epilepticus onset. Epilepsia 1995;36:186-95
    • (1995) Epilepsia , vol.36 , pp. 186-195
    • Fujikawa, D.G.1
  • 16
    • 0028214634 scopus 로고
    • The competitive NMDA receptor antagonist CGP 40116 protects against status epilepticus-induced neuronal damage
    • Fujikawa DG, Daniels AH, Kim JS. The competitive NMDA receptor antagonist CGP 40116 protects against status epilepticus-induced neuronal damage. Epilepsy Res 1994;17:207-19
    • (1994) Epilepsy Res , vol.17 , pp. 207-219
    • Fujikawa, D.G.1    Daniels, A.H.2    Kim, J.S.3
  • 17
    • 0029162231 scopus 로고
    • Subanesthetic doses of ketamine stimulate psychosis in schizophrenia
    • Lahti AC, Koffe lB, LaPorte D, et al. Subanesthetic doses of ketamine stimulate psychosis in schizophrenia. Neuropsychopharmacology 1995; 13:9-19
    • (1995) Neuropsychopharmacology , vol.13 , pp. 9-19
    • Lahti, A.C.1    Lb, K.2    La Porte, D.3
  • 18
    • 0029927565 scopus 로고    scopus 로고
    • NMDA receptor function and human cognition: The effects of ketamine in healthy volunteers
    • Malhotra AK, Pinals DA, Weingartner H, et al. NMDA receptor function and human cognition: The effects of ketamine in healthy volunteers. Neuropsychopharmacology 1996;14:301-7
    • (1996) Neuropsychopharmacology , vol.14 , pp. 301-307
    • Malhotra, A.K.1    Pinals, D.A.2    Weingartner, H.3
  • 19
    • 0028323167 scopus 로고
    • Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses
    • Krystal JH, Karper LP, Seibyl JP, et al. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry 1994;51:199-214
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 199-214
    • Krystal, J.H.1    Karper, L.P.2    Seibyl, J.P.3
  • 20
    • 13944263281 scopus 로고    scopus 로고
    • Selective cognitive impairments associated with NMDA receptor blockade in humans
    • Rowland LM, Astur RS, Jung RE, et al. Selective cognitive impairments associated with NMDA receptor blockade in humans. Neuropsycho-pharmacology 2005;30:633-39
    • (2005) Neuropsychopharmacology , vol.30 , pp. 633-639
    • Rowland, L.M.1    Astur, R.S.2    Jung, R.E.3
  • 21
    • 0026339216 scopus 로고
    • NMDA antagonist neurotoxicity: Mechanism and prevention
    • Olney JW, Labruyere J, Wang G. NMDA antagonist neurotoxicity: Mechanism and prevention. Science 1991;254:1515-18
    • (1991) Science , vol.254 , pp. 1515-1518
    • Olney, J.W.1    Labruyere, J.2    Wang, G.3
  • 22
    • 0024338054 scopus 로고
    • Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs
    • Olney JW, Labruyere J, Price MT. Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science 1989;244:1360-62
    • (1989) Science , vol.244 , pp. 1360-1362
    • Olney, J.W.1    Labruyere, J.2    Price, M.T.3
  • 23
    • 0027521274 scopus 로고
    • Neuronal vacuolization and necrosis induced by the noncompetitive N-methyl-d-aspartate (NMDA) antagonist MK(+) 801 (dizocilpine maleate): A light and electron microscopic evaluation of the rat retrosplenial cortex
    • Fix AS, Horn JW, Wightman KA, et al. Neuronal vacuolization and necrosis induced by the noncompetitive N-methyl-d-aspartate (NMDA) antagonist MK(+)801 (dizocilpine maleate): A light and electron microscopic evaluation of the rat retrosplenial cortex. Exp Neurol 1993;123: 204-15
    • (1993) Exp Neurol , vol.123 , pp. 204-215
    • Fix, A.S.1    Horn, J.W.2    Wightman, K.A.3
  • 24
    • 0037174635 scopus 로고    scopus 로고
    • Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions
    • Aarts M, Liu Y, Liu L, et al. Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions. Science 2002; 298:846-50
    • (2002) Science , vol.298 , pp. 846-850
    • Aarts, M.1    Liu, Y.2    Liu, L.3
  • 25
    • 0033546347 scopus 로고    scopus 로고
    • Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein
    • Sattler R, Xiong Z, Lu WY, et al. Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science 1999; 284:1845-48
    • (1999) Science , vol.284 , pp. 1845-1848
    • Sattler, R.1    Xiong, Z.2    Lu, W.Y.3
  • 26
    • 34548636072 scopus 로고    scopus 로고
    • PDZ Protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors
    • Cui H, Hayashi A, Sun H. PDZ Protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors. J Neurosci 2007;27:9901-15
    • (2007) J Neurosci , vol.27 , pp. 9901-9915
    • Cui, H.1    Hayashi, A.2    Sun, H.3
  • 27
    • 52449107081 scopus 로고    scopus 로고
    • Effectiveness of PSD95 inhibitors in permanent and transient focal ischemia in the rat
    • Sun HS, Doucette TA, Liu YT, et al. Effectiveness of PSD95 inhibitors in permanent and transient focal ischemia in the rat. Stroke 2008;39: 2544-53
    • (2008) Stroke , vol.39 , pp. 2544-2553
    • Sun, H.S.1    Doucette, T.A.2    Liu, Y.T.3
  • 28
    • 0034900665 scopus 로고    scopus 로고
    • Repeated low-dose treatment of rats with pilocarpine: Low mortality but high proportion of rats developing epilepsy
    • Glien M, Brandt C, Potschka H, et al. Repeated low-dose treatment of rats with pilocarpine: Low mortality but high proportion of rats developing epilepsy. Epilepsy Res 2001;46:111
    • (2001) Epilepsy Res , vol.46 , pp. 111
    • Glien, M.1    Brandt, C.2    Potschka, H.3
  • 29
    • 0015309163 scopus 로고
    • Modification of seizure activity by electrical stimulation. II. Motor seizure
    • Racine RJ. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr Clin Neurophysiol 1972;32:281-94
    • (1972) Electroencephalogr Clin Neurophysiol , vol.32 , pp. 281-294
    • Racine, R.J.1
  • 30
    • 0031422511 scopus 로고    scopus 로고
    • Effects of extended electrical kindling on exploratory behavior and spatial learning
    • Cammisuli S, Murphy MP, Ikeda-Douglas CJ, et al. Effects of extended electrical kindling on exploratory behavior and spatial learning. Behav Brain Res 1997;89:179-90
    • (1997) Behav Brain Res , vol.89 , pp. 179-190
    • Cammisuli, S.1    Murphy, M.P.2    Ikeda-Douglas, C.J.3
  • 31
    • 0029098659 scopus 로고
    • Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
    • Kornau H, Schenker LT, Kennedy MB. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 1995;269:1737-40
    • (1995) Science , vol.269 , pp. 1737-1740
    • Kornau, H.1    Schenker, L.T.2    Kennedy, M.B.3
  • 32
    • 0025327731 scopus 로고
    • Unbiased stereological estimation of the number of neurons in the human hippocampus
    • West MJ, Gunderson HJG. Unbiased stereological estimation of the number of neurons in the human hippocampus. J Comp Neurol 1990; 296:1-22
    • (1990) J Comp Neurol , vol.296 , pp. 1-22
    • West, M.J.1    Gunderson, H.J.G.2
  • 33
    • 4744350870 scopus 로고    scopus 로고
    • Stereological quantification of GAD-67-immunoreactive neurons and boutons in the hippocampus of middle-aged and old Fischer 344 x brown norway rats
    • Shi L, Argenta AE, Winseck AK, et al. Stereological quantification of GAD-67-immunoreactive neurons and boutons in the hippocampus of middle-aged and old Fischer 344 x brown Norway rats. J Comp Neurol 2004;478:282-91
    • (2004) J Comp Neurol , vol.478 , pp. 282-291
    • Shi, L.1    Argenta, A.E.2    Winseck, A.K.3
  • 34
    • 0033612565 scopus 로고    scopus 로고
    • Analysis of cell death in the trochlear nucleus of the chick embryo: Calibration of the optical disector counting method reveals systematic bias
    • Hatton WJ, Von Bartheld CS. Analysis of cell death in the trochlear nucleus of the chick embryo: Calibration of the optical disector counting method reveals systematic bias. J Comp Neurol 1999;409:169-86
    • (1999) J Comp Neurol , vol.409 , pp. 169-186
    • Hatton, W.J.1    Von Bartheld, C.S.2
  • 35
    • 13644271600 scopus 로고    scopus 로고
    • Growth hormone prevents neuronal loss in the aged rat hippocampus
    • Azcoitia I, Perez-Martin M, Salazar V, et al. Growth hormone prevents neuronal loss in the aged rat hippocampus. Neurobiol Aging 2005;26: 697-703
    • (2005) Neurobiol Aging , vol.26 , pp. 697-703
    • Azcoitia, I.1    Perez-Martin, M.2    Salazar, V.3
  • 36
    • 0028213822 scopus 로고
    • Practical considerations for the use of the optical dissector in estimating neuronal number
    • Harding AJ, Halliday GM, Cullen K. Practical considerations for the use of the optical dissector in estimating neuronal number. J Neurosci Methods 1994;51:83-89
    • (1994) J Neurosci Methods , vol.51 , pp. 83-89
    • Harding, A.J.1    Halliday, G.M.2    Cullen, K.3
  • 37
    • 0037473243 scopus 로고    scopus 로고
    • Differential tissue shrinkage and compression in the z-axis: Implications for optical disector counting in vibratome-, plastic- and cryosections
    • Gardella D, Hatton WJ, Rind HB, et al. Differential tissue shrinkage and compression in the z-axis: Implications for optical disector counting in vibratome-, plastic- and cryosections. J Neurosci Methods 2003;124: 45-59
    • (2003) J Neurosci Methods , vol.124 , pp. 45-59
    • Gardella, D.1    Hatton, W.J.2    Rind, H.B.3
  • 38
    • 34848875070 scopus 로고    scopus 로고
    • Pathogenesis and pharmacology of epilepsy in the lithium-pilocarpine model
    • Andre V, Dube C, Francois J, et al. Pathogenesis and pharmacology of epilepsy in the lithium-pilocarpine model. Epilepsia 2007;38:41-47
    • (2007) Epilepsia , vol.38 , pp. 41-47
    • Andre, V.1    Dube, C.2    Francois, J.3
  • 39
    • 33947185330 scopus 로고    scopus 로고
    • Preferential neuron loss in the rat piriform cortex following pilocarpine-induced status epilepticus
    • Chen S, Kobayashi M, Honda Y, et al. Preferential neuron loss in the rat piriform cortex following pilocarpine-induced status epilepticus. Epilepsy Res 2007;4:1-18
    • (2007) Epilepsy Res , vol.4 , pp. 1-18
    • Chen, S.1    Kobayashi, M.2    Honda, Y.3
  • 40
    • 0037254320 scopus 로고    scopus 로고
    • Lithium/pilocarpine status epilepticus-induced neuropathology of piriform cortex and adjoining structures in rats is age-dependent
    • Druga R, Kubova H, Suchomelova L, et al. Lithium/pilocarpine status epilepticus-induced neuropathology of piriform cortex and adjoining structures in rats is age-dependent. Physiol Res 2003;52:251-64
    • (2003) Physiol Res , vol.52 , pp. 251-264
    • Druga, R.1    Kubova, H.2    Suchomelova, L.3
  • 41
    • 0023543215 scopus 로고
    • The functional anatomy and pathology of lithium-pilocarpine and high-dose pilocarpine seizures
    • Clifford DB, Olney JW, Maniotis A, et al. The functional anatomy and pathology of lithium-pilocarpine and high-dose pilocarpine seizures. Neuroscience 1987;23:953-68
    • (1987) Neuroscience , vol.23 , pp. 953-968
    • Clifford, D.B.1    Olney, J.W.2    Maniotis, A.3
  • 42
    • 0033982064 scopus 로고    scopus 로고
    • Temporal profile of neuronal injury following pilocarpine or kainic acid-induced status epilepticus
    • Covolan L, Mello LE. Temporal profile of neuronal injury following pilocarpine or kainic acid-induced status epilepticus. Epilepsy Res 2000; 39:133-52
    • (2000) Epilepsy Res , vol.39 , pp. 133-152
    • Covolan, L.1    Mello, L.E.2
  • 43
    • 0030600008 scopus 로고    scopus 로고
    • The temporal evolution of neuronal damage from pilocarpine-induced status epilepticus
    • Fujikawa DG. The temporal evolution of neuronal damage from pilocarpine-induced status epilepticus. Brain Res 1996;725:11-22
    • (1996) Brain Res , vol.725 , pp. 11-22
    • Fujikawa, D.G.1
  • 44
    • 0033951941 scopus 로고    scopus 로고
    • Selfotel in acute ischemic stroke: Possible neurotoxic effects of an NMDA antagonist
    • Davis SM, Lees KR, Albers GW, et al. Selfotel in acute ischemic stroke: Possible neurotoxic effects of an NMDA antagonist. Stroke 2000;31: 347-54
    • (2000) Stroke , vol.31 , pp. 347-354
    • Davis, S.M.1    Lees, K.R.2    Albers, G.W.3
  • 45
    • 70349150293 scopus 로고    scopus 로고
    • Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?
    • Ikonomidou C, Turski L. Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury? Lancet Neurol 2002; 34:235-44
    • (2002) Lancet Neurol , vol.34 , pp. 235-244
    • Ikonomidou, C.1    Turski, L.2
  • 46
    • 30844439634 scopus 로고    scopus 로고
    • Glutamate-based therapeutic approaches: Clinical trials with NMDA antagonists
    • Muir KW. Glutamate-based therapeutic approaches: Clinical trials with NMDA antagonists. Curr Opin Pharmacol 2006;6:53-60
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 53-60
    • Muir, K.W.1
  • 47
    • 0035814418 scopus 로고    scopus 로고
    • Aptiganel hydrochloride in acute ischemic stroke: A randomized controlled trial
    • Albers GW, Goldstein LB, Hall D, et al. Aptiganel hydrochloride in acute ischemic stroke: A randomized controlled trial. JAMA 2001;286: 2673-83
    • (2001) JAMA , vol.286 , pp. 2673-2683
    • Albers, G.W.1    Goldstein, L.B.2    Hall, D.3
  • 48
    • 70349100572 scopus 로고    scopus 로고
    • Safety and tolerability study of aptiganel hydrochloride in patients with an acute ischemic stroke
    • Dyker AG, Edwards KR, Fayad PB, et al. Safety and tolerability study of aptiganel hydrochloride in patients with an acute ischemic stroke. Stroke 1999;39:2544-53
    • (1999) Stroke , vol.39 , pp. 2544-2553
    • Dyker, A.G.1    Edwards, K.R.2    Fayad, P.B.3
  • 49
    • 1842535186 scopus 로고    scopus 로고
    • Molecular mechanisms underlying specificity of excitotoxic signaling in neurons.
    • Aarts MM, Tymianski M. Molecular mechanisms underlying specificity of excitotoxic signaling in neurons. Curr Mol Med 2004;4:137-47
    • (2004) Curr Mol Med , vol.4 , pp. 137-147
    • Aarts, M.M.1    Tymianski, M.2
  • 50
    • 0042536473 scopus 로고    scopus 로고
    • Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity
    • Arundine M, Tymianski M. Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium 2003;34: 325-37
    • (2003) Cell Calcium , vol.34 , pp. 325-337
    • Arundine, M.1    Tymianski, M.2
  • 51
    • 58149460658 scopus 로고    scopus 로고
    • Postsynaptic mechanisms of excitotoxicity: Involvement of postsynaptic density proteins, radicals, and oxidant molecules
    • Forder JP, Tymianski M. Postsynaptic mechanisms of excitotoxicity: Involvement of postsynaptic density proteins, radicals, and oxidant molecules. Neuroscience 2009;158:293-300
    • (2009) Neuroscience , vol.158 , pp. 293-300
    • Forder, J.P.1    Tymianski, M.2
  • 52
    • 0141463724 scopus 로고    scopus 로고
    • Prevention of kainic acid seizures-induced changes in levels of nitric oxide and high-energy phosphates by 7-nitroindazole in rat brain regions
    • Gupta RC, Dettbarn W. Prevention of kainic acid seizures-induced changes in levels of nitric oxide and high-energy phosphates by 7-nitroindazole in rat brain regions. Brain Res 2003;981:184-92
    • (2003) Brain Res , vol.981 , pp. 184-192
    • Gupta, R.C.1    Dettbarn, W.2
  • 53
    • 16744367504 scopus 로고    scopus 로고
    • Inhibition of neuronal (type 1) nitric oxide synthase prevents hyperaemia and hippocampal lesions resulting from kainate-induced seizures
    • Montecot C, Rondi-Reig L, Springhetti V, et al. Inhibition of neuronal (type 1) nitric oxide synthase prevents hyperaemia and hippocampal lesions resulting from kainate-induced seizures. Neuroscience 1998;84: 791-800
    • (1998) Neuroscience , vol.84 , pp. 791-800
    • Montecot, C.1    Rondi-Reig, L.2    Springhetti, V.3
  • 54
    • 0033811674 scopus 로고    scopus 로고
    • Role of nitric oxide in the epilep-togenesis of EL mice
    • Murashima YL, Yoshii M, Suzuki J. Role of nitric oxide in the epilep-togenesis of EL mice. Epilepsia 2000;41:195-99
    • (2000) Epilepsia , vol.41 , pp. 195-199
    • Murashima, Y.L.1    Yoshii, M.2    Suzuki, J.3
  • 55
    • 34548119524 scopus 로고    scopus 로고
    • Modulatory effects of nitric oxide-active drugs on the anticonvulsant activity of lamotrigine in an experimental model of partial complex epilepsy in the rat
    • Sardo P, Ferraro G. Modulatory effects of nitric oxide-active drugs on the anticonvulsant activity of lamotrigine in an experimental model of partial complex epilepsy in the rat. BMC Neurosci 2007;8:47-57
    • (2007) BMC Neurosci , vol.8 , pp. 47-57
    • Sardo, P.1    Ferraro, G.2
  • 56
    • 0037707815 scopus 로고    scopus 로고
    • Increased neuronal nitric oxide synthase (nNOS) activity triggers picrotoxin-induced seizures in rats and evidence for participation of nNOS mechanism in the action of antiepileptic drugs
    • Rajasekaran K, Jayakumar R, Venkatachalam K. Increased neuronal nitric oxide synthase (nNOS) activity triggers picrotoxin-induced seizures in rats and evidence for participation of nNOS mechanism in the action of antiepileptic drugs. Brain Res 2003;979:85-97
    • (2003) Brain Res , vol.979 , pp. 85-97
    • Rajasekaran, K.1    Jayakumar, R.2    Venkatachalam, K.3
  • 57
    • 33750584471 scopus 로고    scopus 로고
    • Molecular signaling mechanisms underlying epileptogenesis
    • McNamara JO, Huang YZ, Leonard S. Molecular signaling mechanisms underlying epileptogenesis. Sci STKE 2006;356:1-17
    • (2006) Sci STKE , vol.356 , pp. 1-17
    • McNamara, J.O.1    Huang, Y.Z.2    Leonard, S.3
  • 58
    • 0001184094 scopus 로고
    • Lorente de NoR. Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system
    • Lorente De NóR. Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system. J Psychol Neurol 1934;46:113-77
    • (1934) J Psychol Neurol , vol.46 , pp. 113-177
  • 59
    • 0028012436 scopus 로고
    • The hippocampal CA3 network: An in-vivo intracellular labeling study
    • Li XG, Somogyi P, Ylinen A, et al. The hippocampal CA3 network: An in-vivo intracellular labeling study. J Compar Neurol 1994;339: 181-208
    • (1994) J Compar Neurol , vol.339 , pp. 181-208
    • Li, X.G.1    Somogyi, P.2    Ylinen, A.3
  • 60
    • 0028249430 scopus 로고
    • Molecular diversity of glutamate receptors and their physiological functions
    • Nakanishi S, Masu M, Bessho Y, et al. Molecular diversity of glutamate receptors and their physiological functions. Experienca 1994;71:71-80
    • (1994) Experienca , vol.71 , pp. 71-80
    • Nakanishi, S.1    Masu, M.2    Bessho, Y.3
  • 61
    • 0035369112 scopus 로고    scopus 로고
    • NMDA receptor subunits: Diversity, development and diseaes
    • Cull-Candy S, Brickley S, Farrant M. NMDA receptor subunits: Diversity, development and diseaes. Curr Opin Neurobiol 2001;11: 327-35
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 327-335
    • Cull-Candy, S.1    Brickley, S.2    Farrant, M.3
  • 62
    • 58149466994 scopus 로고    scopus 로고
    • Delineation of additional PSD-95 binding domains within NMDA receptor NR2 subuntis reveals differences between NR2A/PSD-95 and NR2B/PSD-95 association
    • Cousins SL, Kenny AV, Stephenson FA. Delineation of additional PSD-95 binding domains within NMDA receptor NR2 subuntis reveals differences between NR2A/PSD-95 and NR2B/PSD-95 association. Neuroscience 2009;158:89-95
    • (2009) Neuroscience , vol.158 , pp. 89-95
    • Cousins, S.L.1    Kenny, A.V.2    Stephenson, F.A.3
  • 63
    • 38449093908 scopus 로고    scopus 로고
    • Differential interaction of NMDA receptor subtypes with the post-synaptic density-95 family of membrane associated guanylate kinase proteins
    • Cousins SL, Papadakis M, Rutter R, et al. Differential interaction of NMDA receptor subtypes with the post-synaptic density-95 family of membrane associated guanylate kinase proteins. J Neurochem 2008;104: 903-13
    • (2008) J Neurochem , vol.104 , pp. 903-913
    • Cousins, S.L.1    Papadakis, M.2    Rutter, R.3
  • 64
    • 34547652875 scopus 로고    scopus 로고
    • NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus
    • Al-Hallaq RA, Conrads TP, Veenstra TD, et al. NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus. J Neurosci 2007;27:8334-43
    • (2007) J Neurosci , vol.27 , pp. 8334-8343
    • Al-Hallaq, R.A.1    Conrads, T.P.2    Veenstra, T.D.3
  • 65
    • 0036179194 scopus 로고    scopus 로고
    • Excitotoxicity: Perspectives based on N-methyl-D-aspartate receptor subtypes
    • Lynch DR, Guttmann RP. Excitotoxicity: Perspectives based on N-methyl-D-aspartate receptor subtypes. J Pharmacol Exp Ther 2002; 300:717-23
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 717-723
    • Lynch, D.R.1    Guttmann, R.P.2
  • 66
    • 18044380960 scopus 로고    scopus 로고
    • Differential expression of NMDA receptor subunits and splice variants among the CA1, CA3 and dentate gyrus of the adult rat
    • Coultrap SJ, Nixon KM, Alvestad RM, et al. Differential expression of NMDA receptor subunits and splice variants among the CA1, CA3 and dentate gyrus of the adult rat. Curr Opin Neurobiol 2005;135:104-11
    • (2005) Curr Opin Neurobiol , vol.135 , pp. 104-111
    • Coultrap, S.J.1    Nixon, K.M.2    Alvestad, R.M.3
  • 67
    • 33646378400 scopus 로고    scopus 로고
    • Differential expression of NMDA and AMPA receptor subunits in the rat dorsal and ventral hippocampus
    • Pandis C, Sotiriou E, Kouvaras E, et al. Differential expression of NMDA and AMPA receptor subunits in the rat dorsal and ventral hippocampus. Neurosci 2006;140:163-75
    • (2006) Neurosci , vol.140 , pp. 163-175
    • Pandis, C.1    Sotiriou, E.2    Kouvaras, E.3
  • 68
    • 33847177576 scopus 로고    scopus 로고
    • NMDA receptor-dependent high-frequency network oscillations (100-300 Hz) in rat hippocampal slices
    • Papatheodoropoulos C. NMDA receptor-dependent high-frequency network oscillations (100-300 Hz) in rat hippocampal slices. Neurosci Lett 2007;414:197-202
    • (2007) Neurosci Lett , vol.414 , pp. 197-202
    • Papatheodoropoulos, C.1
  • 69
    • 15244361174 scopus 로고    scopus 로고
    • Changes in phosphorylation of the NMDA receptor in the rat hippocampus induced by status epilepticus
    • Niimura M, Moussa R, Bissoon N, et al. Changes in phosphorylation of the NMDA receptor in the rat hippocampus induced by status epilepticus. J Neurochem 2005;92:1377-85
    • (2005) J Neurochem , vol.92 , pp. 1377-1385
    • Niimura, M.1    Moussa, R.2    Bissoon, N.3
  • 70
    • 0035793014 scopus 로고    scopus 로고
    • Kainate-induced seizures alter protein composition and N-methyl-d-aspartate receptor function of rat forebrain postsynaptic densities
    • Wyneken U, Smalla KH, Marengo JJ, et al. Kainate-induced seizures alter protein composition and N-methyl-d-aspartate receptor function of rat forebrain postsynaptic densities. Neuroscience 2001;102:65-74
    • (2001) Neuroscience , vol.102 , pp. 65-74
    • Wyneken, U.1    Smalla, K.H.2    Marengo, J.J.3
  • 71
    • 33646593166 scopus 로고    scopus 로고
    • Increase in tyrosine phosphorylation of the NMDA receptor following the induction of status epilepticus
    • Huo JZ, Dykstra CM, Gurd JW. Increase in tyrosine phosphorylation of the NMDA receptor following the induction of status epilepticus. Neurosci Lett 2006;401:266-70
    • (2006) Neurosci Lett , vol.401 , pp. 266-270
    • Huo, J.Z.1    Dykstra, C.M.2    Gurd, J.W.3
  • 72
    • 0035500396 scopus 로고    scopus 로고
    • Seizure activity results in increased tyrosine phosphorylation of the N-methyl-D-aspartate receptor in the hippocampus
    • Moussa RC, Ikeda-Douglas CJ, Thakur V, et al. Seizure activity results in increased tyrosine phosphorylation of the N-methyl-D-aspartate receptor in the hippocampus. Mol Brain Res 2001;95:36-47
    • (2001) Mol Brain Res , vol.95 , pp. 36-47
    • Moussa, R.C.1    Ikeda-Douglas, C.J.2    Thakur, V.3
  • 73
    • 0033520487 scopus 로고    scopus 로고
    • In vivo protein transduction: Delivery of a biologically active protein into the mouse
    • Schwarze SR, Ho A, Vocero-Akbani A, et al. In vivo protein transduction: Delivery of a biologically active protein into the mouse. Science 1999;285:1569-72
    • (1999) Science , vol.285 , pp. 1569-1572
    • Schwarze, S.R.1    Ho, A.2    Vocero-Akbani, A.3
  • 74
    • 57349141812 scopus 로고    scopus 로고
    • A role for leukocyte-endothelial adhesion mechanisms in epilepsy
    • Fabene PF, Navarro MG, Martinello M, et al. A role for leukocyte-endothelial adhesion mechanisms in epilepsy. Nat Med 2008;14: 1377-83
    • (2008) Nat Med , vol.14 , pp. 1377-1383
    • Fabene, P.F.1    Navarro, M.G.2    Martinello, M.3
  • 75
    • 33846629927 scopus 로고    scopus 로고
    • Blood-brain barrier leakage may lead to progression of temporal lobe epilepsy
    • van Vliet EA, da Costa Araujo S, Redeker S, et al. Blood-brain barrier leakage may lead to progression of temporal lobe epilepsy. Brain 2007; 130:521-34
    • (2007) Brain , vol.130 , pp. 521-534
    • Van Vliet, E.A.1    Da Costa Araujo, S.2    Redeker, S.3
  • 76
    • 57349141812 scopus 로고    scopus 로고
    • A role for leukocyte-endothelial adhesion mechanisms in epilepsy
    • Fabene PF, Mora GN, Martinello M, et al. A role for leukocyte-endothelial adhesion mechanisms in epilepsy. Nat Med 2008;14:1377-83
    • (2008) Nat Med , vol.14 , pp. 1377-1383
    • Fabene, P.F.1    Mora, G.N.2    Martinello, M.3
  • 77
    • 33747828519 scopus 로고    scopus 로고
    • Treatment with valproate after status epilepticus: Effect on neuronal damage, epileptogenesis, and behavioral alterations in rats
    • Brandt C, Gastens AM, Sun MZ, et al. Treatment with valproate after status epilepticus: Effect on neuronal damage, epileptogenesis, and behavioral alterations in rats. Neuropharmacology 2006;51:789-804
    • (2006) Neuropharmacology , vol.51 , pp. 789-804
    • Brandt, C.1    Gastens, A.M.2    Sun, M.Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.