A HA2-Fusion tag limits the endosomal release of its protein cargo despite causing endosomal lysis

Biochimica et Biophysica Acta - General Subjects

Volumn 1810, Issue 8, 2011, Pages 752-758

  Lee, Ya Jung ^a   Johnson, Gregory ^a   Peltier, Grantham C ^a   Pellois, Jean Philippe ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Endosomal escape; HA2 peptide; Lysis; Protein delivery; Protein transduction domain

Indexed keywords

HEMAGGLUTININ; HYBRID PROTEIN; TRANSACTIVATOR PROTEIN;

ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOLYSIS; DISULFIDE BOND; ENDOSOME; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN LOCALIZATION; PROTEIN SECRETION;

ENDOSOMES; HELA CELLS; HN PROTEIN; HUMANS; INFLUENZA A VIRUS; RECOMBINANT FUSION PROTEINS;

EID: 79959190803     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2011.05.013     Document Type: Article

References (29)

1. J.S. Wadia, and S.F. Dowdy Protein transduction technology Curr. Opin. Biotechnol. 13 2002 52 56 (Pubitemid 34146548)
2. M. Zorko, and U. Langel Cell-penetrating peptides: mechanism and kinetics of cargo delivery Adv. Drug Deliv. Rev. 57 2005 529 545 (Pubitemid 40255559)
3. H.L. Amand, K. Fant, B. Norden, and E.K. Esbjorner Stimulated endocytosis in penetratin uptake: effect of arginine and lysine Biochem. Biophys. Res. Commun. 371 2008 621 625
4. J.S. Wadia, R.V. Stan, and S.F. Dowdy Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis Nat. Med. 10 2004 310 315 (Pubitemid 38667624)
5. I.M. Kaplan, J.S. Wadia, and S.F. Dowdy Cationic TAT peptide transduction domain enters cells by macropinocytosis J. Control. Release 102 2005 247 253 (Pubitemid 40093789)
6. Y.J. Lee, S. Datta, and J.P. Pellois Real-time fluorescence detection of protein transduction into live cells J. Am. Chem. Soc. 130 2008 2398 2399 (Pubitemid 351304730)
7. A. El-Sayed, S. Futaki, and H. Harashima Delivery of macromolecules using arginine-rich cell-penetrating peptides: ways to overcome endosomal entrapment AAPS J. 11 2009 13 22
8. M. Forgac Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology Nat. Rev. Mol. Cell Biol. 8 2007 917 929 (Pubitemid 47622561)
9. A.E. Smith, and A. Helenius How viruses enter animal cells Science 304 2004 237 242 (Pubitemid 38452168)
10. S.A. Wharton, S.R. Martin, R.W. Ruigrok, J.J. Skehel, and D.C. Wiley Membrane fusion by peptide analogues of influenza virus haemagglutinin J. Gen. Virol. 69 Pt 8 1988 1847 1857
11. L.K. Tamm, and X. Han Viral fusion peptides: a tool set to disrupt and connect biological membranes Biosci. Rep. 20 2000 501 518 (Pubitemid 32523208)
12. D.V. Zhelev, N. Stoicheva, P. Scherrer, and D. Needham Interaction of synthetic HA2 influenza fusion peptide analog with model membranes Biophys. J. 81 2001 285 304 (Pubitemid 32605970)
13. Y.J. Lee, G. Johnson, and J.P. Pellois Modeling of the endosomolytic activity of HA2-TAT peptides with red blood cells and ghosts Biochemistry 49 2010 7854 7866
14. E. Wagner, C. Plank, K. Zatloukal, M. Cotten, and M.L. Birnstiel Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle Proc. Natl. Acad. Sci. U.S.A. 89 1992 7934 7938
15. C. Plank, B. Oberhauser, K. Mechtler, C. Koch, and E. Wagner The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems J. Biol. Chem. 269 1994 12918 12924 (Pubitemid 24202092)
16. E. Mastrobattista, G.A. Koning, L. van Bloois, A.C. Filipe, W. Jiskoot, and G. Storm Functional characterization of an endosome-disruptive peptide and its application in cytosolic delivery of immunoliposome-entrapped proteins J. Biol. Chem. 277 2002 27135 27143 (Pubitemid 34951728)
17. P. Lundberg, S. El-Andaloussi, T. Sutlu, H. Johansson, and U. Langel Delivery of short interfering RNA using endosomolytic cell-penetrating peptides FASEB J. 21 2007 2664 2671 (Pubitemid 47372734)
18. Y.J. Lee, A. Erazo-Oliveras, and J.P. Pellois Delivery of macromolecules into live cells by simple co-incubation with a peptide Chembiochem 11 2010 325 330
19. H. Michiue, K. Tomizawa, F.Y. Wei, M. Matsushita, Y.F. Lu, T. Ichikawa, T. Tamiya, I. Date, and H. Matsui The NH2 terminus of influenza virus hemagglutinin-2 subunit peptides enhances the antitumor potency of polyarginine-mediated p53 protein transduction J. Biol. Chem. 280 2005 8285 8289 (Pubitemid 40349730)
20. M. Murata, S. Takahashi, S. Kagiwada, A. Suzuki, and S. Ohnishi pH-dependent membrane fusion and vesiculation of phospholipid large unilamellar vesicles induced by amphiphilic anionic and cationic peptides Biochemistry 31 1992 1986 1992
21. E.K. Esbjörner, K. Oglecka, P. Lincoln, A. Gräslund, and B. Nordén Membrane binding of pH-sensitive influenza fusion peptides. positioning, configuration, and induced leakage in a lipid vesicle model Biochemistry 46 2007 13490 13504 (Pubitemid 350209946)
22. M. Murata, S. Kagiwada, R. Hishida, R. Ishiguro, S. Ohnishi, and S. Takahashi Modification of the N-terminus of membrane fusion-active peptides blocks the fusion activity Biochem. Biophys. Res. Commun. 179 1991 1050 1055
23. N.C. Shaner, R.E. Campbell, P.A. Steinbach, B.N. Giepmans, A.E. Palmer, and R.Y. Tsien Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein Nat. Biotechnol. 22 2004 1567 1572 (Pubitemid 40039460)
24. S.T. Yang, E. Zaitseva, L.V. Chernomordik, and K. Melikov Cell-penetrating peptide induces leaky fusion of liposomes containing late endosome-specific anionic lipid Biophys. J. 99 2010 2525 2533
25. S. Hakansson, A. Jacobs, and M. Caffrey Heparin binding by the HIV-1 tat protein transduction domain Protein Sci. 10 2001 2138 2139 (Pubitemid 32911233)
26. M. Rusnati, D. Coltrini, P. Oreste, G. Zoppetti, A. Albini, D. Noonan, F. d'Adda di Fagagna, M. Giacca, and M. Presta Interaction of HIV-1 Tat protein with heparin. Role of the backbone structure, sulfation, and size J. Biol. Chem. 272 1997 11313 11320 (Pubitemid 27184133)
27. P.E. Thoren, D. Persson, E.K. Esbjorner, M. Goksor, P. Lincoln, and B. Norden Membrane binding and translocation of cell-penetrating peptides Biochemistry 43 2004 3471 3489 (Pubitemid 38391703)
28. V. Tiriveedhi, and P. Butko A fluorescence spectroscopy study on the interactions of the TAT-PTD peptide with model lipid membranes Biochemistry 46 2007 3888 3895 (Pubitemid 46493489)
29. P. Lenart, G. Rabut, N. Daigle, A.R. Hand, M. Terasaki, and J. Ellenberg Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes J. Cell Biol. 160 2003 1055 1068 (Pubitemid 36443874)