Neuroprotection with noninvasive neurotrophin delivery to the brain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 1, 1999, Pages 254-259

  Wu, Dafang ^a   Pardridge, William M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Blood brain barrier; Brain derived neurotrophic factor; Drug targeting; Polyethylene glycol conjugation

Indexed keywords

BIOTIN; BRAIN DERIVED NEUROTROPHIC FACTOR; MACROGOL; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY OX 26; STREPTAVIDIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CELL DENSITY; CONTROLLED STUDY; DRUG CONJUGATION; DRUG FORMULATION; DRUG TRANSPORT; HIPPOCAMPUS; INTRAVENOUS DRUG ADMINISTRATION; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIBODIES, MONOCLONAL; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN ISCHEMIA; BRAIN-DERIVED NEUROTROPHIC FACTOR; DRUG DESIGN; ELECTROENCEPHALOGRAPHY; ENDOTHELIUM, VASCULAR; HUMANS; IMMUNOCONJUGATES; INJECTIONS, INTRAVENOUS; POLYETHYLENE GLYCOLS; PROSENCEPHALON; PYRAMIDAL CELLS; RATS; RECEPTORS, TRANSFERRIN;

ANIMALIA; HIPPOCAMPUS HIPPOCAMPUS;

EID: 0033524392     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.1.254     Document Type: Article

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