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Volumn 327, Issue 1-2, 2012, Pages 142-152

Molecular markers for cancer prognosis and treatment: Have we struck gold?

Author keywords

Biomarkers; Cancer; DNA damage; Epigenetics; Inflammation; Personalized treatment

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CA 15-3 ANTIGEN; CA 19-9 ANTIGEN; CA 27-29 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CHEMOKINE; CHEMOKINE CCL18; CXCL1 CHEMOKINE; CYTOKERATIN; CYTOKERATIN 19 FRAGMENT; DNA DEPENDENT PROTEIN KINASE; DOCKING PROTEIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; GAMMA HISTONE H2AX; HISTONE H2AX; K RAS PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROGESTERONE RECEPTOR; PROSTATE SPECIFIC ANTIGEN; PROTEIN KU80; PYRUVATE KINASE; RAD51 PROTEIN; TUMOR M2 PYRUVATE KINASE; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84867449930     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.11.022     Document Type: Review
Times cited : (33)

References (162)
  • 2
    • 79956191022 scopus 로고    scopus 로고
    • Role of oxidative stress and DNA damage in human carcinogenesis
    • Kryston T.B., Georgiev A., Georgakilas A.G. Role of oxidative stress and DNA damage in human carcinogenesis. Mutat. Res. 2011, 711:193-201.
    • (2011) Mutat. Res. , vol.711 , pp. 193-201
    • Kryston, T.B.1    Georgiev, A.2    Georgakilas, A.G.3
  • 7
    • 41649102043 scopus 로고    scopus 로고
    • The cancer biomarker problem
    • Sawyers C.L. The cancer biomarker problem. Nature 2008, 452:548-552.
    • (2008) Nature , vol.452 , pp. 548-552
    • Sawyers, C.L.1
  • 8
    • 79956189660 scopus 로고    scopus 로고
    • From chemistry of DNA damage to repair and biological significance. Comprehending the future
    • Georgakilas A.G. From chemistry of DNA damage to repair and biological significance. Comprehending the future. Mutat. Res. 2011, 711:1-2.
    • (2011) Mutat. Res. , vol.711 , pp. 1-2
    • Georgakilas, A.G.1
  • 9
    • 79959473659 scopus 로고    scopus 로고
    • Identifying responders to trastuzumab therapy in breast cancer
    • Brugmann A., Sorensen B.S. Identifying responders to trastuzumab therapy in breast cancer. Future Oncol. 2011, 7:767-773.
    • (2011) Future Oncol. , vol.7 , pp. 767-773
    • Brugmann, A.1    Sorensen, B.S.2
  • 13
    • 79960090146 scopus 로고    scopus 로고
    • PSA and the family physician
    • Barkin J. PSA and the family physician. Can. J. Urol. 2011, 18(Suppl.):20-23.
    • (2011) Can. J. Urol. , vol.18 , Issue.SUPPL. , pp. 20-23
    • Barkin, J.1
  • 14
    • 79957456529 scopus 로고    scopus 로고
    • Tumour markers in prostate cancer II: Diagnostic and prognostic cellular biomarkers
    • Bjartell A., Montironi R., Berney D.M., Egevad L. Tumour markers in prostate cancer II: Diagnostic and prognostic cellular biomarkers. Acta Oncol. 2011, 50(Suppl. 1):76-84.
    • (2011) Acta Oncol. , vol.50 , Issue.SUPPL. 1 , pp. 76-84
    • Bjartell, A.1    Montironi, R.2    Berney, D.M.3    Egevad, L.4
  • 15
    • 77954609077 scopus 로고    scopus 로고
    • Thyroid tumor marker genomics and proteomics: diagnostic and clinical implications
    • Carpi A., Mechanick J.I., Saussez S., Nicolini A. Thyroid tumor marker genomics and proteomics: diagnostic and clinical implications. J. Cell. Physiol. 2010, 224:612-619.
    • (2010) J. Cell. Physiol. , vol.224 , pp. 612-619
    • Carpi, A.1    Mechanick, J.I.2    Saussez, S.3    Nicolini, A.4
  • 17
    • 79956304968 scopus 로고    scopus 로고
    • Molecular diagnostics of thyroid tumors
    • Nikiforov Y.E. Molecular diagnostics of thyroid tumors. Arch. Pathol. Lab. Med. 2011, 135:569-577.
    • (2011) Arch. Pathol. Lab. Med. , vol.135 , pp. 569-577
    • Nikiforov, Y.E.1
  • 18
    • 80054003601 scopus 로고    scopus 로고
    • Ovarian cancer screening and mortality
    • (author reply 1544-1545)
    • Menon U., Gentry-Maharaj A., Jacobs I. Ovarian cancer screening and mortality. J. Am. Med. Assoc. 2011, 306:1544. (author reply 1544-1545).
    • (2011) J. Am. Med. Assoc. , vol.306 , pp. 1544
    • Menon, U.1    Gentry-Maharaj, A.2    Jacobs, I.3
  • 19
    • 84867444543 scopus 로고    scopus 로고
    • Measurement of the minimum apparent diffusion coefficient (ADCmin) of the primary tumor and CA125 are predictive of disease recurrence for patients with endometrial cancer
    • Nakamura K., Imafuku N., Nishida T., Niwa I., Joja I., Hongo A., Kodama J., Hiramatsu Y. Measurement of the minimum apparent diffusion coefficient (ADCmin) of the primary tumor and CA125 are predictive of disease recurrence for patients with endometrial cancer. Gynecol. Oncol. 2011.
    • (2011) Gynecol. Oncol.
    • Nakamura, K.1    Imafuku, N.2    Nishida, T.3    Niwa, I.4    Joja, I.5    Hongo, A.6    Kodama, J.7    Hiramatsu, Y.8
  • 21
    • 78649844980 scopus 로고    scopus 로고
    • Proteomics technologies for the global identification and quantification of proteins
    • Brewis I.A., Brennan P. Proteomics technologies for the global identification and quantification of proteins. Adv. Protein Chem. Struct. Biol. 2010, 80:1-44.
    • (2010) Adv. Protein Chem. Struct. Biol. , vol.80 , pp. 1-44
    • Brewis, I.A.1    Brennan, P.2
  • 22
    • 79951868206 scopus 로고    scopus 로고
    • Clinical proteomics: current status, challenges, and future perspectives
    • Chiou S.H., Wu C.Y. Clinical proteomics: current status, challenges, and future perspectives. Kaohsiung J. Med. Sci. 2010, 27:1-14.
    • (2010) Kaohsiung J. Med. Sci. , vol.27 , pp. 1-14
    • Chiou, S.H.1    Wu, C.Y.2
  • 23
    • 41649100689 scopus 로고    scopus 로고
    • Mining the plasma proteome for cancer biomarkers
    • Hanash S.M., Pitteri S.J., Faca V.M. Mining the plasma proteome for cancer biomarkers. Nature 2008, 452:571-579.
    • (2008) Nature , vol.452 , pp. 571-579
    • Hanash, S.M.1    Pitteri, S.J.2    Faca, V.M.3
  • 24
    • 67649447179 scopus 로고    scopus 로고
    • Proteomics: biomarkers on a nanoscale
    • Alderton G.K. Proteomics: biomarkers on a nanoscale. Nat. Rev. Cancer 2009, 9:382-383.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 382-383
    • Alderton, G.K.1
  • 25
    • 77957956535 scopus 로고    scopus 로고
    • Tracing cancer networks with phosphoproteomics
    • Solit D.B., Mellinghoff I.K. Tracing cancer networks with phosphoproteomics. Nat. Biotechnol. 2010, 28:1028-1029.
    • (2010) Nat. Biotechnol. , vol.28 , pp. 1028-1029
    • Solit, D.B.1    Mellinghoff, I.K.2
  • 26
    • 79551503762 scopus 로고    scopus 로고
    • Catch me if you can: mass spectrometry-based phosphoproteomics and quantification strategies
    • Eyrich B., Sickmann A., Zahedi R.P. Catch me if you can: mass spectrometry-based phosphoproteomics and quantification strategies. Proteomics 2011, 11:554-570.
    • (2011) Proteomics , vol.11 , pp. 554-570
    • Eyrich, B.1    Sickmann, A.2    Zahedi, R.P.3
  • 28
    • 70349131530 scopus 로고    scopus 로고
    • The phosphoproteomics data explosion
    • Lemeer S., Heck A.J. The phosphoproteomics data explosion. Curr. Opin. Chem. Biol. 2009, 13:414-420.
    • (2009) Curr. Opin. Chem. Biol. , vol.13 , pp. 414-420
    • Lemeer, S.1    Heck, A.J.2
  • 32
    • 70349189541 scopus 로고    scopus 로고
    • Genomic and proteomic biomarkers for cancer: a multitude of opportunities
    • Tainsky M.A. Genomic and proteomic biomarkers for cancer: a multitude of opportunities. Biochim. Biophys. Acta 2009, 1796:176-193.
    • (2009) Biochim. Biophys. Acta , vol.1796 , pp. 176-193
    • Tainsky, M.A.1
  • 33
    • 79952502199 scopus 로고    scopus 로고
    • Metabolomics: a novel approach to early and noninvasive prostate cancer detection
    • Roberts M.J., Schirra H.J., Lavin M.F., Gardiner R.A. Metabolomics: a novel approach to early and noninvasive prostate cancer detection. Korean J. Urol. 2011, 52:79-89.
    • (2011) Korean J. Urol. , vol.52 , pp. 79-89
    • Roberts, M.J.1    Schirra, H.J.2    Lavin, M.F.3    Gardiner, R.A.4
  • 34
  • 35
    • 77957988570 scopus 로고    scopus 로고
    • The oncotype DX recurrence score is correlated with a composite index including routinely reported pathobiologic features
    • Geradts J., Bean S.M., Bentley R.C., Barry W.T. The oncotype DX recurrence score is correlated with a composite index including routinely reported pathobiologic features. Cancer Invest. 2010, 28:969-977.
    • (2010) Cancer Invest. , vol.28 , pp. 969-977
    • Geradts, J.1    Bean, S.M.2    Bentley, R.C.3    Barry, W.T.4
  • 36
    • 79961195719 scopus 로고    scopus 로고
    • Cell-free DNA in the circulation as a potential cancer biomarker
    • Kohler C., Barekati Z., Radpour R., Zhong X.Y. Cell-free DNA in the circulation as a potential cancer biomarker. Anticancer Res. 2011, 31:2623-2628.
    • (2011) Anticancer Res. , vol.31 , pp. 2623-2628
    • Kohler, C.1    Barekati, Z.2    Radpour, R.3    Zhong, X.Y.4
  • 38
    • 79953737346 scopus 로고    scopus 로고
    • Saliva: diagnostics and therapeutic perspectives
    • Spielmann N., Wong D.T. Saliva: diagnostics and therapeutic perspectives. Oral Dis. 2010, 17:345-354.
    • (2010) Oral Dis. , vol.17 , pp. 345-354
    • Spielmann, N.1    Wong, D.T.2
  • 39
    • 0035129627 scopus 로고    scopus 로고
    • Molecular characterization of minimal residual cancer cells in patients with solid tumors
    • Bockmann B., Grill H.J., Giesing M. Molecular characterization of minimal residual cancer cells in patients with solid tumors. Biomol. Eng. 2001, 17:95-111.
    • (2001) Biomol. Eng. , vol.17 , pp. 95-111
    • Bockmann, B.1    Grill, H.J.2    Giesing, M.3
  • 40
    • 22944461059 scopus 로고    scopus 로고
    • Somatic mutations in human cancer: applications in molecular epidemiology
    • Le Roux E., Gormally E., Hainaut P. Somatic mutations in human cancer: applications in molecular epidemiology. Rev. Epidemiol. Sante Publique 2005, 53:257-266.
    • (2005) Rev. Epidemiol. Sante Publique , vol.53 , pp. 257-266
    • Le Roux, E.1    Gormally, E.2    Hainaut, P.3
  • 41
    • 34447628522 scopus 로고    scopus 로고
    • Technology insight: microarrays - research and clinical applications
    • Vlacich G., Roe C., Webb G.C. Technology insight: microarrays - research and clinical applications. Nat. Clin. Pract. Endocrinol. Metab. 2007, 3:594-605.
    • (2007) Nat. Clin. Pract. Endocrinol. Metab. , vol.3 , pp. 594-605
    • Vlacich, G.1    Roe, C.2    Webb, G.C.3
  • 42
    • 84860598176 scopus 로고    scopus 로고
    • Role of circulating tumor cells and disseminated tumor cells in primary breast cancer
    • Hayashi N., Yamauchi H. Role of circulating tumor cells and disseminated tumor cells in primary breast cancer. Breast Cancer 2011, 10.1007/s12282-12011-10282-12285.
    • (2011) Breast Cancer
    • Hayashi, N.1    Yamauchi, H.2
  • 44
    • 0035129003 scopus 로고    scopus 로고
    • P53, but not c-Ki-ras, mutation and down-regulation of p21WAF1/CIP1 and cyclin D1 are associated with malignant transformation in gastric hyperplastic polyps
    • Murakami K., Mitomi H., Yamashita K., Tanabe S., Saigenji K., Okayasu I. P53, but not c-Ki-ras, mutation and down-regulation of p21WAF1/CIP1 and cyclin D1 are associated with malignant transformation in gastric hyperplastic polyps. Am. J. Clin. Pathol. 2001, 115:224-234.
    • (2001) Am. J. Clin. Pathol. , vol.115 , pp. 224-234
    • Murakami, K.1    Mitomi, H.2    Yamashita, K.3    Tanabe, S.4    Saigenji, K.5    Okayasu, I.6
  • 47
    • 84856089946 scopus 로고    scopus 로고
    • Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases
    • Patel A.S., Allen J.E., Dicker D.T., Peters K.L., Sheehan J.M., Glantz M.J., El-Deiry W.S. Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases. Oncotarget 2011.
    • (2011) Oncotarget
    • Patel, A.S.1    Allen, J.E.2    Dicker, D.T.3    Peters, K.L.4    Sheehan, J.M.5    Glantz, M.J.6    El-Deiry, W.S.7
  • 49
    • 80051903574 scopus 로고    scopus 로고
    • Prognostic significance of micropapillary pattern in lung adenocarcinoma and expression of apoptosis-related markers: caspase-3, bcl-2, and p53
    • Cakir E., Yilmaz A., Demirag F., Oguztuzun S., Sahin S., Yazici U.E., Aydin M. Prognostic significance of micropapillary pattern in lung adenocarcinoma and expression of apoptosis-related markers: caspase-3, bcl-2, and p53. APMIS 2011, 119:574-580.
    • (2011) APMIS , vol.119 , pp. 574-580
    • Cakir, E.1    Yilmaz, A.2    Demirag, F.3    Oguztuzun, S.4    Sahin, S.5    Yazici, U.E.6    Aydin, M.7
  • 50
    • 80051925916 scopus 로고    scopus 로고
    • Prognostic significance of angiogenesis and angiogenic growth factors in nonsmall cell lung cancer
    • Salgia R. Prognostic significance of angiogenesis and angiogenic growth factors in nonsmall cell lung cancer. Cancer 2011, 117:3889-3899.
    • (2011) Cancer , vol.117 , pp. 3889-3899
    • Salgia, R.1
  • 51
    • 74049130251 scopus 로고    scopus 로고
    • Designing early detection programs for ovarian cancer
    • Hartge P. Designing early detection programs for ovarian cancer. J. Natl. Cancer Inst. 2009, 102:3-4.
    • (2009) J. Natl. Cancer Inst. , vol.102 , pp. 3-4
    • Hartge, P.1
  • 52
    • 77951739129 scopus 로고    scopus 로고
    • Identification of pancreatic juice proteins as biomarkers of pancreatic cancer
    • Gao J., Zhu F., Lv S., Li Z., Ling Z., Gong Y., Jie C., Ma L. Identification of pancreatic juice proteins as biomarkers of pancreatic cancer. Oncol. Rep. 2010, 23:1683-1692.
    • (2010) Oncol. Rep. , vol.23 , pp. 1683-1692
    • Gao, J.1    Zhu, F.2    Lv, S.3    Li, Z.4    Ling, Z.5    Gong, Y.6    Jie, C.7    Ma, L.8
  • 57
    • 6044253696 scopus 로고    scopus 로고
    • Effect of human papillomavirus-16 infection on CD8+ T-cell recognition of a wild-type sequence p53264-272 peptide in patients with squamous cell carcinoma of the head and neck
    • Sirianni N., Ha P.K., Oelke M., Califano J., Gooding W., Westra W., Whiteside T.L., Koch W.M., Schneck J.P., DeLeo A., Ferris R.L. Effect of human papillomavirus-16 infection on CD8+ T-cell recognition of a wild-type sequence p53264-272 peptide in patients with squamous cell carcinoma of the head and neck. Clin. Cancer Res. 2004, 10:6929-6937.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 6929-6937
    • Sirianni, N.1    Ha, P.K.2    Oelke, M.3    Califano, J.4    Gooding, W.5    Westra, W.6    Whiteside, T.L.7    Koch, W.M.8    Schneck, J.P.9    DeLeo, A.10    Ferris, R.L.11
  • 58
    • 15244363807 scopus 로고    scopus 로고
    • Antiviral activity of Cidofovir on a naturally human papillomavirus-16 infected squamous cell carcinoma of the head and neck (SCCHN) cell line improves radiation sensitivity
    • Sirianni N., Wang J., Ferris R.L. Antiviral activity of Cidofovir on a naturally human papillomavirus-16 infected squamous cell carcinoma of the head and neck (SCCHN) cell line improves radiation sensitivity. Oral Oncol. 2005, 41:423-428.
    • (2005) Oral Oncol. , vol.41 , pp. 423-428
    • Sirianni, N.1    Wang, J.2    Ferris, R.L.3
  • 61
    • 0036720810 scopus 로고    scopus 로고
    • Human papillomavirus and p53 mutational status as prognostic factors in head and neck carcinoma
    • Sisk E.A., Soltys S.G., Zhu S., Fisher S.G., Carey T.E., Bradford C.R. Human papillomavirus and p53 mutational status as prognostic factors in head and neck carcinoma. Head Neck 2002, 24:841-849.
    • (2002) Head Neck , vol.24 , pp. 841-849
    • Sisk, E.A.1    Soltys, S.G.2    Zhu, S.3    Fisher, S.G.4    Carey, T.E.5    Bradford, C.R.6
  • 62
    • 37149027578 scopus 로고    scopus 로고
    • Processing of DNA damage clusters in human cells: current status of knowledge
    • Georgakilas A.G. Processing of DNA damage clusters in human cells: current status of knowledge. Mol. BioSyst. 2008, 4:30-35.
    • (2008) Mol. BioSyst. , vol.4 , pp. 30-35
    • Georgakilas, A.G.1
  • 63
    • 77950360354 scopus 로고    scopus 로고
    • Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage
    • Eccles L.J., Lomax M.E., O'Neill P. Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage. Nucleic Acids Res. 2010, 38:1123-1134.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 1123-1134
    • Eccles, L.J.1    Lomax, M.E.2    O'Neill, P.3
  • 64
    • 10044272594 scopus 로고    scopus 로고
    • Two clustered 8-oxo-7, 8-dihydroguanine (8-oxodG) lesions increase the point mutation frequency of 8-oxodG, but do not result in double strand breaks or deletions in Escherichia coli
    • Malyarchuk S., Brame K.L., Youngblood R., Shi R., Harrison L. Two clustered 8-oxo-7, 8-dihydroguanine (8-oxodG) lesions increase the point mutation frequency of 8-oxodG, but do not result in double strand breaks or deletions in Escherichia coli. Nucleic Acids Res. 2004, 32:5721-5731.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 5721-5731
    • Malyarchuk, S.1    Brame, K.L.2    Youngblood, R.3    Shi, R.4    Harrison, L.5
  • 65
    • 54149098939 scopus 로고    scopus 로고
    • Clustered DNA lesion sites as a source of mutations during human colorectal tumourigenesis
    • Radford I.R., Lobachevsky P.N. Clustered DNA lesion sites as a source of mutations during human colorectal tumourigenesis. Mutat. Res. 2008, 646:60-68.
    • (2008) Mutat. Res. , vol.646 , pp. 60-68
    • Radford, I.R.1    Lobachevsky, P.N.2
  • 66
    • 0036829211 scopus 로고    scopus 로고
    • Clustered DNA damage leads to complex genetic changes in irradiated human cells
    • Singleton B.K., Griffin C.S., Thacker J. Clustered DNA damage leads to complex genetic changes in irradiated human cells. Cancer Res. 2002, 62:6263-6269.
    • (2002) Cancer Res. , vol.62 , pp. 6263-6269
    • Singleton, B.K.1    Griffin, C.S.2    Thacker, J.3
  • 68
    • 79957686784 scopus 로고    scopus 로고
    • Unrepaired clustered DNA lesions induce chromosome breakage in human cells
    • Asaithamby A., Hu B., Chen D.J. Unrepaired clustered DNA lesions induce chromosome breakage in human cells. Proc. Natl. Acad. Sci. USA 2011, 10.1073/pnas.1016045108.
    • (2011) Proc. Natl. Acad. Sci. USA
    • Asaithamby, A.1    Hu, B.2    Chen, D.J.3
  • 74
    • 79956215808 scopus 로고    scopus 로고
    • Induction and repair of DNA double strand breaks: The increasing spectrum of non-homologous end joining pathways
    • Mladenov E., Iliakis G. Induction and repair of DNA double strand breaks: The increasing spectrum of non-homologous end joining pathways. Mutat. Res. 2011, 711:61-72.
    • (2011) Mutat. Res. , vol.711 , pp. 61-72
    • Mladenov, E.1    Iliakis, G.2
  • 75
    • 34250831508 scopus 로고    scopus 로고
    • Interplay between DNA N-glycosylases/AP lyases at multiply damaged sites and biological consequences
    • Eot-Houllier G., Gonera M., Gasparutto D., Giustranti C., Sage E. Interplay between DNA N-glycosylases/AP lyases at multiply damaged sites and biological consequences. Nucleic Acids Res. 2007, 35:3355-3366.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 3355-3366
    • Eot-Houllier, G.1    Gonera, M.2    Gasparutto, D.3    Giustranti, C.4    Sage, E.5
  • 77
    • 84856414968 scopus 로고    scopus 로고
    • Detection of clustered DNA lesions: Biological and clinical applications
    • Georgakilas A.G. Detection of clustered DNA lesions: Biological and clinical applications. World J. Biol. Chem. 2011, 2:173-176.
    • (2011) World J. Biol. Chem. , vol.2 , pp. 173-176
    • Georgakilas, A.G.1
  • 78
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: safeguarding genome integrity
    • Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 2003, 3:155-168.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 79
    • 46049114741 scopus 로고    scopus 로고
    • Prognostic significance of ataxia-telangiectasia mutated, DNA-dependent protein kinase catalytic subunit, and Ku heterodimeric regulatory complex 86-kD subunit expression in patients with nonsmall cell lung cancer
    • Xing J., Wu X., Vaporciyan A.A., Spitz M.R., Gu J. Prognostic significance of ataxia-telangiectasia mutated, DNA-dependent protein kinase catalytic subunit, and Ku heterodimeric regulatory complex 86-kD subunit expression in patients with nonsmall cell lung cancer. Cancer 2008, 112:2756-2764.
    • (2008) Cancer , vol.112 , pp. 2756-2764
    • Xing, J.1    Wu, X.2    Vaporciyan, A.A.3    Spitz, M.R.4    Gu, J.5
  • 80
    • 34247612295 scopus 로고    scopus 로고
    • Expression patterns of the ATM gene in mammary tissues and their associations with breast cancer survival
    • Ye C., Cai Q., Dai Q., Shu X.-o., Shin A., Gao Y.-T., Zheng W. Expression patterns of the ATM gene in mammary tissues and their associations with breast cancer survival. Cancer 2007, 109:1729-1735.
    • (2007) Cancer , vol.109 , pp. 1729-1735
    • Ye, C.1    Cai, Q.2    Dai, Q.3    Shu, X.-O.4    Shin, A.5    Gao, Y.-T.6    Zheng, W.7
  • 81
    • 38049155945 scopus 로고    scopus 로고
    • Regulation of DNA double-strand break repair pathway choice
    • Shrivastav M., De Haro L.P., Nickoloff J.A. Regulation of DNA double-strand break repair pathway choice. Cell Res. 2008, 18:134-147.
    • (2008) Cell Res. , vol.18 , pp. 134-147
    • Shrivastav, M.1    De Haro, L.P.2    Nickoloff, J.A.3
  • 84
    • 76649094290 scopus 로고    scopus 로고
    • Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130
    • Hegan D.C., Lu Y., Stachelek G.C., Crosby M.E., Bindra R.S., Glazer P.M. Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130. Proc. Natl. Acad. Sci. USA 2011, 107:2201-2206.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 2201-2206
    • Hegan, D.C.1    Lu, Y.2    Stachelek, G.C.3    Crosby, M.E.4    Bindra, R.S.5    Glazer, P.M.6
  • 86
    • 77954352775 scopus 로고    scopus 로고
    • Expression of 53BP1 as a cisplatin-resistant marker in patients with lung adenocarcinomas
    • Lai T.C., Chow K.C., Lin T.Y., Chiang I.P., Fang H.Y., Chen C.Y., Ho S.P. Expression of 53BP1 as a cisplatin-resistant marker in patients with lung adenocarcinomas. Oncol. Rep. 2010, 24:321-328.
    • (2010) Oncol. Rep. , vol.24 , pp. 321-328
    • Lai, T.C.1    Chow, K.C.2    Lin, T.Y.3    Chiang, I.P.4    Fang, H.Y.5    Chen, C.Y.6    Ho, S.P.7
  • 88
    • 49149087379 scopus 로고    scopus 로고
    • A novel poly(ADP-ribose) polymerase inhibitor, ABT-888, radiosensitizes malignant human cell lines under hypoxia
    • Liu S.K., Coackley C., Krause M., Jalali F., Chan N., Bristow R.G. A novel poly(ADP-ribose) polymerase inhibitor, ABT-888, radiosensitizes malignant human cell lines under hypoxia. Radiother. Oncol. 2008, 88:258-268.
    • (2008) Radiother. Oncol. , vol.88 , pp. 258-268
    • Liu, S.K.1    Coackley, C.2    Krause, M.3    Jalali, F.4    Chan, N.5    Bristow, R.G.6
  • 89
    • 79960359070 scopus 로고    scopus 로고
    • The poly (ADP-Ribose) polymerase inhibitor ABT-888 reduces nuclear EGFR and augments head and neck tumor response to radiotherapy
    • Nowsheen S., Bonner J.A., Yang E.S. The poly (ADP-Ribose) polymerase inhibitor ABT-888 reduces nuclear EGFR and augments head and neck tumor response to radiotherapy. Radiother. Oncol. 2011.
    • (2011) Radiother. Oncol.
    • Nowsheen, S.1    Bonner, J.A.2    Yang, E.S.3
  • 90
    • 77953373821 scopus 로고    scopus 로고
    • Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair
    • Löser D.A., Shibata A., Shibata A.K., Woodbine L.J., Jeggo P.A., Chalmers A.J. Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair. Mol. Cancer Ther. 2011, 9:1775-1787.
    • (2011) Mol. Cancer Ther. , vol.9 , pp. 1775-1787
    • Löser, D.A.1    Shibata, A.2    Shibata, A.K.3    Woodbine, L.J.4    Jeggo, P.A.5    Chalmers, A.J.6
  • 93
    • 79959743541 scopus 로고    scopus 로고
    • AC480, formerly BMS-599626, a pan Her inhibitor, enhances radiosensitivity and radioresponse of head and neck squamous cell carcinoma cells in vitro and in vivo
    • Torres M., Raju U., Molkentine D., Riesterer O., Milas L., Ang K. AC480, formerly BMS-599626, a pan Her inhibitor, enhances radiosensitivity and radioresponse of head and neck squamous cell carcinoma cells in vitro and in vivo. Invest. New Drugs 2011, 29:554-561.
    • (2011) Invest. New Drugs , vol.29 , pp. 554-561
    • Torres, M.1    Raju, U.2    Molkentine, D.3    Riesterer, O.4    Milas, L.5    Ang, K.6
  • 94
    • 78149358861 scopus 로고    scopus 로고
    • ErbB2 expression through heterodimerization with erbB1 is necessary for ionizing radiation- but not EGF-induced activation of Akt survival pathway
    • Toulany M., Minjgee M., Kehlbach R., Chen J., Baumann M., Rodemann H.P. ErbB2 expression through heterodimerization with erbB1 is necessary for ionizing radiation- but not EGF-induced activation of Akt survival pathway. Radiother. Oncol. 2010, 97:338-345.
    • (2010) Radiother. Oncol. , vol.97 , pp. 338-345
    • Toulany, M.1    Minjgee, M.2    Kehlbach, R.3    Chen, J.4    Baumann, M.5    Rodemann, H.P.6
  • 95
    • 56449098784 scopus 로고    scopus 로고
    • Erlotinib attenuates homologous recombinational repair of chromosomal breaks in human breast cancer cells
    • Li L., Wang H., Yang E.S., Arteaga C.L., Xia F. Erlotinib attenuates homologous recombinational repair of chromosomal breaks in human breast cancer cells. Cancer Res. 2008, 68:9141-9146.
    • (2008) Cancer Res. , vol.68 , pp. 9141-9146
    • Li, L.1    Wang, H.2    Yang, E.S.3    Arteaga, C.L.4    Xia, F.5
  • 96
    • 75649095683 scopus 로고    scopus 로고
    • Nuclear EGFR as novel therapeutic target: insights into nuclear translocation and function
    • Dittmann K., Mayer C., Rodemann H. Nuclear EGFR as novel therapeutic target: insights into nuclear translocation and function. Strahlenther. Onkol. 2010, 186:1-6.
    • (2010) Strahlenther. Onkol. , vol.186 , pp. 1-6
    • Dittmann, K.1    Mayer, C.2    Rodemann, H.3
  • 97
    • 5144220297 scopus 로고    scopus 로고
    • Modulation of DNA repair in vitro after treatment with chemotherapeutic agents by the epidermal growth factor receptor inhibitor Gefitinib (ZD1839)
    • Friedmann B., Caplin M., Hartley J.A., Hochhauser D. Modulation of DNA repair in vitro after treatment with chemotherapeutic agents by the epidermal growth factor receptor inhibitor Gefitinib (ZD1839). Clin. Cancer Res. 2004, 10:6476-6486.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 6476-6486
    • Friedmann, B.1    Caplin, M.2    Hartley, J.A.3    Hochhauser, D.4
  • 99
    • 66149094649 scopus 로고    scopus 로고
    • Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells
    • Golding S.E., Morgan R.N., Adams B.R., Hawkins A.J., Povirk L.F., Valerie K. Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells. Cancer Biol. Ther. 2009, 8:730-738.
    • (2009) Cancer Biol. Ther. , vol.8 , pp. 730-738
    • Golding, S.E.1    Morgan, R.N.2    Adams, B.R.3    Hawkins, A.J.4    Povirk, L.F.5    Valerie, K.6
  • 100
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon D.S., Brandt R., Ciardiello F., Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit. Rev. Oncol. Hematol. 1995, 19:183-232.
    • (1995) Crit. Rev. Oncol. Hematol. , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 101
    • 79952276644 scopus 로고    scopus 로고
    • CLEOPATRA: a phase III evaluation of pertuzumab and trastuzumab for HER2-positive metastatic breast cancer
    • Baselga J., Swain S.M. CLEOPATRA: a phase III evaluation of pertuzumab and trastuzumab for HER2-positive metastatic breast cancer. Clin. Breast Cancer 2010, 10:489-491.
    • (2010) Clin. Breast Cancer , vol.10 , pp. 489-491
    • Baselga, J.1    Swain, S.M.2
  • 102
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: the complexity of targeted inhibitors
    • Hynes N.E., Lane H.A. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat. Rev. Cancer 2005, 5:341-354.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 104
    • 77952548502 scopus 로고    scopus 로고
    • Protein overexpression and gene amplification of epidermal growth factor receptor in nonsmall cell lung carcinomas: Comparison of four commercially available antibodies by immunohistochemistry and fluorescence in situ hybridization study
    • Lee H.J., Xu X., Choe G., Chung D.H., Seo J.-W., Lee J.H., Lee C.-T., Jheon S., Sung S.-W., Chung J.-H. Protein overexpression and gene amplification of epidermal growth factor receptor in nonsmall cell lung carcinomas: Comparison of four commercially available antibodies by immunohistochemistry and fluorescence in situ hybridization study. Lung Cancer 2010, 68:375-382.
    • (2010) Lung Cancer , vol.68 , pp. 375-382
    • Lee, H.J.1    Xu, X.2    Choe, G.3    Chung, D.H.4    Seo, J.-W.5    Lee, J.H.6    Lee, C.-T.7    Jheon, S.8    Sung, S.-W.9    Chung, J.-H.10
  • 108
    • 62349115537 scopus 로고    scopus 로고
    • Human epidermal growth factor receptor-2 family in colorectal adenocarcinoma: correlation with survival and clinicopathological findings
    • Molaei M., Pejhan S., Nayer B.N., Moradi A., Ghiasi S., Zali M.R. Human epidermal growth factor receptor-2 family in colorectal adenocarcinoma: correlation with survival and clinicopathological findings. Eur. J. Gastroenterol. Hepatol. 2009, 21:289-293.
    • (2009) Eur. J. Gastroenterol. Hepatol. , vol.21 , pp. 289-293
    • Molaei, M.1    Pejhan, S.2    Nayer, B.N.3    Moradi, A.4    Ghiasi, S.5    Zali, M.R.6
  • 109
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., Bonner W.M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 1998, 273:5858-5868.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 110
    • 0035834693 scopus 로고    scopus 로고
    • ATM phosphorylates histone H2AX in response to DNA double-strand breaks
    • Burma S., Chen B.P., Murphy M., Kurimasa A., Chen D.J. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem. 2001, 276:42462-42467.
    • (2001) J. Biol. Chem. , vol.276 , pp. 42462-42467
    • Burma, S.1    Chen, B.P.2    Murphy, M.3    Kurimasa, A.4    Chen, D.J.5
  • 112
    • 84867473149 scopus 로고    scopus 로고
    • GammaH2AX in cancer cells: a potential biomarker for cancer diagnostics, prediction and recurrence
    • Sedelnikova O.A., Bonner W.M. GammaH2AX in cancer cells: a potential biomarker for cancer diagnostics, prediction and recurrence. Cell Cycle 2006, 5:231-240.
    • (2006) Cell Cycle , vol.5 , pp. 231-240
    • Sedelnikova, O.A.1    Bonner, W.M.2
  • 119
    • 19344371580 scopus 로고    scopus 로고
    • The DNA repair gene ERCC2/XPD polymorphism Arg 156Arg (A22541C) and risk of lung cancer in a Chinese population
    • Yin J., Li J., Ma Y., Guo L., Wang H., Vogel U. The DNA repair gene ERCC2/XPD polymorphism Arg 156Arg (A22541C) and risk of lung cancer in a Chinese population. Cancer Lett. 2005, 223:219-226.
    • (2005) Cancer Lett. , vol.223 , pp. 219-226
    • Yin, J.1    Li, J.2    Ma, Y.3    Guo, L.4    Wang, H.5    Vogel, U.6
  • 121
    • 70349813980 scopus 로고    scopus 로고
    • Polymorphisms in the nucleotide excision repair gene ERCC2/XPD and risk of non-Hodgkin lymphoma
    • Worrillow L., Roman E., Adamson P.J., Kane E., Allan J.M., Lightfoot T.J. Polymorphisms in the nucleotide excision repair gene ERCC2/XPD and risk of non-Hodgkin lymphoma. Cancer Epidemiol. 2009, 33:257-260.
    • (2009) Cancer Epidemiol. , vol.33 , pp. 257-260
    • Worrillow, L.1    Roman, E.2    Adamson, P.J.3    Kane, E.4    Allan, J.M.5    Lightfoot, T.J.6
  • 123
    • 65549123024 scopus 로고    scopus 로고
    • Genetic susceptibility to esophageal cancer: the role of the nucleotide excision repair pathway
    • Pan J., Lin J., Izzo J.G., Liu Y., Xing J., Huang M., Ajani J.A., Wu X. Genetic susceptibility to esophageal cancer: the role of the nucleotide excision repair pathway. Carcinogenesis 2009, 30:785-792.
    • (2009) Carcinogenesis , vol.30 , pp. 785-792
    • Pan, J.1    Lin, J.2    Izzo, J.G.3    Liu, Y.4    Xing, J.5    Huang, M.6    Ajani, J.A.7    Wu, X.8
  • 125
    • 40949130371 scopus 로고    scopus 로고
    • Platinum resistance: the role of DNA repair pathways
    • Martin L.P., Hamilton T.C., Schilder R.J. Platinum resistance: the role of DNA repair pathways. Clin. Cancer Res. 2008, 14:1291-1295.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 1291-1295
    • Martin, L.P.1    Hamilton, T.C.2    Schilder, R.J.3
  • 126
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
    • Colotta F., Allavena P., Sica A., Garlanda C., Mantovani A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 2009, 30:1073-1081.
    • (2009) Carcinogenesis , vol.30 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3    Garlanda, C.4    Mantovani, A.5
  • 127
    • 79953750882 scopus 로고    scopus 로고
    • Chemokines and cancer: a fatal attraction
    • Bonecchi R., Locati M., Mantovani A. Chemokines and cancer: a fatal attraction. Cancer Cell 2011, 19:434-435.
    • (2011) Cancer Cell , vol.19 , pp. 434-435
    • Bonecchi, R.1    Locati, M.2    Mantovani, A.3
  • 129
    • 84555208284 scopus 로고    scopus 로고
    • Evaluation of proteomics-identified CCL18 and CXCL1 as circulating tumor markers for differential diagnosis between ovarian carcinomas and benign pelvic masses
    • Wang Q., Li D., Zhang W., Tang B.L., Li Q.Q., Li L. Evaluation of proteomics-identified CCL18 and CXCL1 as circulating tumor markers for differential diagnosis between ovarian carcinomas and benign pelvic masses. Int. J. Biol. Markers 2011, 10.5301/JBM.2011.8616.
    • (2011) Int. J. Biol. Markers
    • Wang, Q.1    Li, D.2    Zhang, W.3    Tang, B.L.4    Li, Q.Q.5    Li, L.6
  • 130
    • 3242876403 scopus 로고    scopus 로고
    • Genetic biomarkers of therapeutic radiation sensitivity
    • Fernet M., Hall J. Genetic biomarkers of therapeutic radiation sensitivity. DNA Repair (Amst) 2004, 3:1237-1243.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 1237-1243
    • Fernet, M.1    Hall, J.2
  • 131
    • 34748856245 scopus 로고    scopus 로고
    • Use of molecular biomarkers for predicting the response to radiotherapy with or without chemotherapy
    • Riesterer O., Milas L., Ang K.K. Use of molecular biomarkers for predicting the response to radiotherapy with or without chemotherapy. J. Clin. Oncol. 2007, 25:4075-4083.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 4075-4083
    • Riesterer, O.1    Milas, L.2    Ang, K.K.3
  • 134
    • 0030693736 scopus 로고    scopus 로고
    • The early detection of prostate carcinoma with prostate specific antigen: the Washington University experience
    • Smith D.S., Humphrey P.A., Catalona W.J. The early detection of prostate carcinoma with prostate specific antigen: the Washington University experience. Cancer 1997, 80:1852-1856.
    • (1997) Cancer , vol.80 , pp. 1852-1856
    • Smith, D.S.1    Humphrey, P.A.2    Catalona, W.J.3
  • 136
    • 79951974161 scopus 로고    scopus 로고
    • Phase III randomized study comparing docetaxel plus trastuzumab with vinorelbine plus trastuzumab as first-line therapy of metastatic or locally advanced human epidermal growth factor receptor 2-positive breast cancer: the HERNATA study
    • Andersson M., Lidbrink E., Bjerre K., Wist E., Enevoldsen K., Jensen A.B., Karlsson P., Tange U.B., Sorensen P.G., Moller S., Bergh J., Langkjer S.T. Phase III randomized study comparing docetaxel plus trastuzumab with vinorelbine plus trastuzumab as first-line therapy of metastatic or locally advanced human epidermal growth factor receptor 2-positive breast cancer: the HERNATA study. J. Clin. Oncol. 2010, 29:264-271.
    • (2010) J. Clin. Oncol. , vol.29 , pp. 264-271
    • Andersson, M.1    Lidbrink, E.2    Bjerre, K.3    Wist, E.4    Enevoldsen, K.5    Jensen, A.B.6    Karlsson, P.7    Tange, U.B.8    Sorensen, P.G.9    Moller, S.10    Bergh, J.11    Langkjer, S.T.12
  • 138
    • 79952278668 scopus 로고    scopus 로고
    • Phase II trial of combination of pegylated liposomal doxorubicin, cisplatin, and infusional 5-fluorouracil (CCF) plus trastuzumab as preoperative treatment for locally advanced and inflammatory breast cancer
    • Torrisi R., Cardillo A., Cancello G., Dellapasqua S., Balduzzi A., Ghisini R., Luini A., Veronesi P., Viale G., Goldhirsch A., Colleoni M. Phase II trial of combination of pegylated liposomal doxorubicin, cisplatin, and infusional 5-fluorouracil (CCF) plus trastuzumab as preoperative treatment for locally advanced and inflammatory breast cancer. Clin. Breast Cancer 2010, 10:483-488.
    • (2010) Clin. Breast Cancer , vol.10 , pp. 483-488
    • Torrisi, R.1    Cardillo, A.2    Cancello, G.3    Dellapasqua, S.4    Balduzzi, A.5    Ghisini, R.6    Luini, A.7    Veronesi, P.8    Viale, G.9    Goldhirsch, A.10    Colleoni, M.11
  • 139
    • 0035119545 scopus 로고    scopus 로고
    • CA27.29: a valuable marker for breast cancer management. A confirmatory multicentric study on 603 cases
    • Gion M., Mione R., Leon A.E., Lüftner D., Molina R., Possinger K., Robertson J.F. CA27.29: a valuable marker for breast cancer management. A confirmatory multicentric study on 603 cases. Eur. J. Cancer 2001, 37:355-363.
    • (2001) Eur. J. Cancer , vol.37 , pp. 355-363
    • Gion, M.1    Mione, R.2    Leon, A.E.3    Lüftner, D.4    Molina, R.5    Possinger, K.6    Robertson, J.F.7
  • 141
    • 79952842455 scopus 로고    scopus 로고
    • CK8/18 expression, the basal phenotype, and family history in identifying BRCA1-associated breast cancer in the Ontario site of the breast cancer family registry
    • Mulligan A.M., Pinnaduwage D., Bane A.L., Bull S.B., O'Malley F.P., Andrulis I.L. CK8/18 expression, the basal phenotype, and family history in identifying BRCA1-associated breast cancer in the Ontario site of the breast cancer family registry. Cancer 2011, 117:1350-1359.
    • (2011) Cancer , vol.117 , pp. 1350-1359
    • Mulligan, A.M.1    Pinnaduwage, D.2    Bane, A.L.3    Bull, S.B.4    O'Malley, F.P.5    Andrulis, I.L.6
  • 142
    • 79951660042 scopus 로고    scopus 로고
    • Cytology of indeterminate cases (C3). Can this diagnostic class be improved?
    • Fiaccavento S., Simone G. Cytology of indeterminate cases (C3). Can this diagnostic class be improved?. Pathologica 2011, 102:409-413.
    • (2011) Pathologica , vol.102 , pp. 409-413
    • Fiaccavento, S.1    Simone, G.2
  • 143
    • 79959228670 scopus 로고    scopus 로고
    • Multiple biomarker expression on circulating tumor cells in comparison to tumor tissues from primary and metastatic sites in patients with locally advanced/inflammatory, and stage IV breast cancer, using a novel detection technology
    • Somlo G., Lau S.K., Frankel P., Hsieh H.B., Liu X., Yang L., Krivacic R., Bruce R.H. Multiple biomarker expression on circulating tumor cells in comparison to tumor tissues from primary and metastatic sites in patients with locally advanced/inflammatory, and stage IV breast cancer, using a novel detection technology. Breast Cancer Res. Treat. 2011, 128:155-163.
    • (2011) Breast Cancer Res. Treat. , vol.128 , pp. 155-163
    • Somlo, G.1    Lau, S.K.2    Frankel, P.3    Hsieh, H.B.4    Liu, X.5    Yang, L.6    Krivacic, R.7    Bruce, R.H.8
  • 145
    • 77956247826 scopus 로고    scopus 로고
    • Multigene assays and isolated tumor cells for early breast cancer treatment: time for bionetworks
    • Roukos D.H., Ziogas D.E., Katsios C. Multigene assays and isolated tumor cells for early breast cancer treatment: time for bionetworks. Expert Rev. Anticancer Ther. 2010, 10:1187-1195.
    • (2010) Expert Rev. Anticancer Ther. , vol.10 , pp. 1187-1195
    • Roukos, D.H.1    Ziogas, D.E.2    Katsios, C.3
  • 148
    • 79959990401 scopus 로고    scopus 로고
    • Current status of vandetanib (ZD6474) in the treatment of non-small cell lung cancer
    • Flanigan J., Deshpande H., Gettinger S. Current status of vandetanib (ZD6474) in the treatment of non-small cell lung cancer. Biologics 2010, 4:237-243.
    • (2010) Biologics , vol.4 , pp. 237-243
    • Flanigan, J.1    Deshpande, H.2    Gettinger, S.3
  • 149
    • 78149426819 scopus 로고    scopus 로고
    • Cetuximab monotherapy in patients with advanced non-small cell lung cancer after prior epidermal growth factor receptor tyrosine kinase inhibitor therapy
    • Neal J.W., Heist R.S., Fidias P., Temel J.S., Huberman M., Marcoux J.P., Muzikansky A., Lynch T.J., Sequist L.V. Cetuximab monotherapy in patients with advanced non-small cell lung cancer after prior epidermal growth factor receptor tyrosine kinase inhibitor therapy. J. Thorac. Oncol. 2010, 5:1855-1858.
    • (2010) J. Thorac. Oncol. , vol.5 , pp. 1855-1858
    • Neal, J.W.1    Heist, R.S.2    Fidias, P.3    Temel, J.S.4    Huberman, M.5    Marcoux, J.P.6    Muzikansky, A.7    Lynch, T.J.8    Sequist, L.V.9
  • 151
    • 79551711737 scopus 로고    scopus 로고
    • Biomarker-based phase I dose-escalation, pharmacokinetic, and pharmacodynamic study of oral apricoxib in combination with erlotinib in advanced nonsmall cell lung cancer
    • Reckamp K., Gitlitz B., Chen L.C., Patel R., Milne G., Syto M., Jezior D., Zaknoen S. Biomarker-based phase I dose-escalation, pharmacokinetic, and pharmacodynamic study of oral apricoxib in combination with erlotinib in advanced nonsmall cell lung cancer. Cancer 2010, 117:809-818.
    • (2010) Cancer , vol.117 , pp. 809-818
    • Reckamp, K.1    Gitlitz, B.2    Chen, L.C.3    Patel, R.4    Milne, G.5    Syto, M.6    Jezior, D.7    Zaknoen, S.8
  • 153
    • 60549088708 scopus 로고    scopus 로고
    • Diagnostic precision of carcinoembryonic antigen in the detection of recurrence of colorectal cancer
    • Tan E., Gouvas N., Nicholls R.J., Ziprin P., Xynos E., Tekkis P.P. Diagnostic precision of carcinoembryonic antigen in the detection of recurrence of colorectal cancer. Surg. Oncol. 2009, 18:15-24.
    • (2009) Surg. Oncol. , vol.18 , pp. 15-24
    • Tan, E.1    Gouvas, N.2    Nicholls, R.J.3    Ziprin, P.4    Xynos, E.5    Tekkis, P.P.6
  • 156
    • 33845314341 scopus 로고    scopus 로고
    • The cancer genome and diagnostic blood tests
    • Lance P. The cancer genome and diagnostic blood tests. Cancer Epidemiol. Biomarkers Prev. 2006, 15:2017-2018.
    • (2006) Cancer Epidemiol. Biomarkers Prev. , vol.15 , pp. 2017-2018
    • Lance, P.1
  • 158
    • 78651080669 scopus 로고    scopus 로고
    • Predictive and prognostic biomarkers for targeted therapy in metastatic colorectal cancer
    • Asghar U., Hawkes E., Cunningham D. Predictive and prognostic biomarkers for targeted therapy in metastatic colorectal cancer. Clin. Colorectal Cancer 2010, 9:274-281.
    • (2010) Clin. Colorectal Cancer , vol.9 , pp. 274-281
    • Asghar, U.1    Hawkes, E.2    Cunningham, D.3
  • 159
    • 80052725362 scopus 로고    scopus 로고
    • Oncotype DX tumor gene expression profiling in stage II colon cancer. Application: prognostic, risk prediction
    • Webber E.M., Lin J.S., Evelyn P.W. Oncotype DX tumor gene expression profiling in stage II colon cancer. Application: prognostic, risk prediction. PLoS Curr. 2010, 2.
    • (2010) PLoS Curr. , vol.2
    • Webber, E.M.1    Lin, J.S.2    Evelyn, P.W.3
  • 160
    • 77956595357 scopus 로고    scopus 로고
    • Human papillomavirus and oropharynx cancer: biology, detection and clinical implications
    • Allen C.T., Lewis J.S., El-Mofty S.K., Haughey B.H., Nussenbaum B. Human papillomavirus and oropharynx cancer: biology, detection and clinical implications. Laryngoscope 2010, 120:1756-1772.
    • (2010) Laryngoscope , vol.120 , pp. 1756-1772
    • Allen, C.T.1    Lewis, J.S.2    El-Mofty, S.K.3    Haughey, B.H.4    Nussenbaum, B.5
  • 162
    • 79953151232 scopus 로고    scopus 로고
    • Molecular and cellular bases of chronic myeloid leukemia
    • Chen Y., Peng C., Li D., Li S. Molecular and cellular bases of chronic myeloid leukemia. Protein Cell 2011, 1:124-132.
    • (2011) Protein Cell , vol.1 , pp. 124-132
    • Chen, Y.1    Peng, C.2    Li, D.3    Li, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.