메뉴 건너뛰기




Volumn 25, Issue 1, 2006, Pages 222-231

Interplay between human DNA repair proteins at a unique double-strand break in vivo

Author keywords

DNA repair; Genome stability; Homologous recombination; RAD51; RAD51 paralogs

Indexed keywords

DOUBLE STRANDED DNA; MRE11 PROTEIN; NUCLEIC ACID BINDING PROTEIN; PROTEIN; PROTEIN 53BP1; PROTEIN KU80; PROTEIN RAD51B; PROTEIN RAD51C; PROTEIN RAD51D; PROTEIN XRCC2; PROTEIN XRCC3; RAD51 PROTEIN; UNCLASSIFIED DRUG;

EID: 30444445118     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600914     Document Type: Article
Times cited : (172)

References (42)
  • 2
    • 14644413615 scopus 로고    scopus 로고
    • Differing requirements for the Arabidopsis Rad51 paralogs in meiosis and DNA repair
    • Bleuyard JY, Gallego ME, Savigny F, White CI (2005) Differing requirements for the Arabidopsis Rad51 paralogs in meiosis and DNA repair. Plant J 41: 533-545
    • (2005) Plant J , vol.41 , pp. 533-545
    • Bleuyard, J.Y.1    Gallego, M.E.2    Savigny, F.3    White, C.I.4
  • 3
    • 1542380555 scopus 로고    scopus 로고
    • The Arabidopsis homologue of Xrcc3 plays an essential role in meiosis
    • Bleuyard JY, White CI (2004) The Arabidopsis homologue of Xrcc3 plays an essential role in meiosis. EMBO J 23: 439-449
    • (2004) EMBO J , vol.23 , pp. 439-449
    • Bleuyard, J.Y.1    White, C.I.2
  • 4
    • 0036671755 scopus 로고    scopus 로고
    • XRCC3 controls the fidelity of homologous recombination: Roles for XRCC3 in late stages of recombination
    • Brenneman MA, Wagener BM, Miller CA, Allen C, Nickoloff JA (2002) XRCC3 controls the fidelity of homologous recombination: roles for XRCC3 in late stages of recombination. Mol Cell 10: 387-395
    • (2002) Mol Cell , vol.10 , pp. 387-395
    • Brenneman, M.A.1    Wagener, B.M.2    Miller, C.A.3    Allen, C.4    Nickoloff, J.A.5
  • 5
    • 0034672057 scopus 로고    scopus 로고
    • Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice
    • Deans B, Griffin CS, Maconochie M, Thacker J (2000) Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice. EMBO J 19: 6675-6685
    • (2000) EMBO J , vol.19 , pp. 6675-6685
    • Deans, B.1    Griffin, C.S.2    Maconochie, M.3    Thacker, J.4
  • 7
    • 16644377060 scopus 로고    scopus 로고
    • Xrcc3 is recruited to DNA double strand breaks early and independent of Rad51
    • Forget AL, Bennett BT, Knight KL (2004) Xrcc3 is recruited to DNA double strand breaks early and independent of Rad51. J Cell Biochem 93: 429-436
    • (2004) J Cell Biochem , vol.93 , pp. 429-436
    • Forget, A.L.1    Bennett, B.T.2    Knight, K.L.3
  • 9
    • 0242580932 scopus 로고    scopus 로고
    • Identification of functional domains in the RAD51L2 (RAD51C) protein and its requirement for gene conversion
    • French CA, Tambini CE, Thacker J (2003) Identification of functional domains in the RAD51L2 (RAD51C) protein and its requirement for gene conversion. J Biol Chem 278: 45445-45450
    • (2003) J Biol Chem , vol.278 , pp. 45445-45450
    • French, C.A.1    Tambini, C.E.2    Thacker, J.3
  • 13
    • 2642528031 scopus 로고    scopus 로고
    • DNA damage-induced activation of ATM and ATM-dependent signaling pathways
    • Kurz EU, Lees-Miller SP (2004) DNA damage-induced activation of ATM and ATM-dependent signaling pathways. DNA Repair (Amsterdam) 3: 889-900
    • (2004) DNA Repair (Amsterdam) , vol.3 , pp. 889-900
    • Kurz, E.U.1    Lees-Miller, S.P.2
  • 14
    • 26944488710 scopus 로고    scopus 로고
    • The AtRAD51C gene is required for normal meiotic chromosome synapsis and double-stranded break repair in Arabidopsis
    • Li W, Yang X, Lin Z, Timofejeva L, Xiao R, Makaroff CA, Ma H (2005) The AtRAD51C gene is required for normal meiotic chromosome synapsis and double-stranded break repair in Arabidopsis. Plant Physiol 138: 965-976
    • (2005) Plant Physiol , vol.138 , pp. 965-976
    • Li, W.1    Yang, X.2    Lin, Z.3    Timofejeva, L.4    Xiao, R.5    Makaroff, C.A.6    Ma, H.7
  • 15
    • 0037462657 scopus 로고    scopus 로고
    • Complex formation by the human Rad51B and Rad51C DNA repair proteins and their activities in vitro
    • Lio YC, Mazin AV, Kowalczykowski SC, Chen DJ (2003) Complex formation by the human Rad51B and Rad51C DNA repair proteins and their activities in vitro. J Biol Chem 278: 2469-2478
    • (2003) J Biol Chem , vol.278 , pp. 2469-2478
    • Lio, Y.C.1    Mazin, A.V.2    Kowalczykowski, S.C.3    Chen, D.J.4
  • 16
    • 4744360979 scopus 로고    scopus 로고
    • Human Rad51C deficiency destabilizes XRCC3, impairs recombination, and radiosensitizes S/G2-phase cells
    • Lio YC, Schild D, Brenneman MA, Redpath JL, Chen DJ (2004) Human Rad51C deficiency destabilizes XRCC3, impairs recombination, and radiosensitizes S/G2-phase cells. J Biol Chem 279: 42313-42320
    • (2004) J Biol Chem , vol.279 , pp. 42313-42320
    • Lio, Y.C.1    Schild, D.2    Brenneman, M.A.3    Redpath, J.L.4    Chen, D.J.5
  • 17
    • 0037082427 scopus 로고    scopus 로고
    • Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells
    • Liu N, Schild D, Thelen MP, Thompson LH (2002) Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells. Nucleic Acids Res 30: 1009-1015
    • (2002) Nucleic Acids Res , vol.30 , pp. 1009-1015
    • Liu, N.1    Schild, D.2    Thelen, M.P.3    Thompson, L.H.4
  • 18
    • 0346340054 scopus 로고    scopus 로고
    • RAD51C is required for Holliday junction processing in mammalian cells
    • Liu Y, Masson JY, Shah R, O'Regan P, West SC (2004) RAD51C is required for Holliday junction processing in mammalian cells. Science 303: 243-246
    • (2004) Science , vol.303 , pp. 243-246
    • Liu, Y.1    Masson, J.Y.2    Shah, R.3    O'Regan, P.4    West, S.C.5
  • 22
    • 0037040996 scopus 로고    scopus 로고
    • RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51
    • Miller KA, Yoshikawa DM, McConnell IR, Clark R, Schild D, Albala JS (2002) RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51. J Biol Chem 277: 8406-8411
    • (2002) J Biol Chem , vol.277 , pp. 8406-8411
    • Miller, K.A.1    Yoshikawa, D.M.2    McConnell, I.R.3    Clark, R.4    Schild, D.5    Albala, J.S.6
  • 23
    • 1842509858 scopus 로고    scopus 로고
    • In vivo assembly and disassembly of Rad51 and Rad52 complexes during double-strand break repair
    • Miyazaki T, Bressan DA, Shinohara M, Haber JE, Shinohara A (2004) In vivo assembly and disassembly of Rad51 and Rad52 complexes during double-strand break repair. EMBO J 23: 939-949
    • (2004) EMBO J , vol.23 , pp. 939-949
    • Miyazaki, T.1    Bressan, D.A.2    Shinohara, M.3    Haber, J.E.4    Shinohara, A.5
  • 24
    • 0034612307 scopus 로고    scopus 로고
    • A mechanistic basis for Mre11-directed DNA joining at microhomologies
    • Paull TT, Gellert M (2000) A mechanistic basis for Mre11-directed DNA joining at microhomologies. Proc Natl Acad Sci USA 97: 6409-6414
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6409-6414
    • Paull, T.T.1    Gellert, M.2
  • 25
    • 0035893363 scopus 로고    scopus 로고
    • Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
    • Pierce AJ, Hu P, Han MG, Ellis N, Jasin M (2001) Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev 15: 3237-3242
    • (2001) Genes Dev , vol.15 , pp. 3237-3242
    • Pierce, A.J.1    Hu, P.2    Han, M.G.3    Ellis, N.4    Jasin, M.5
  • 26
    • 0033569684 scopus 로고    scopus 로고
    • XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
    • Pierce AJ, Johnson RD, Thompson LH, Jasin M (1999) XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev 13: 2633-2638
    • (1999) Genes Dev , vol.13 , pp. 2633-2638
    • Pierce, A.J.1    Johnson, R.D.2    Thompson, L.H.3    Jasin, M.4
  • 27
    • 0034074273 scopus 로고    scopus 로고
    • Mid-gestation lethality in mice deficient for the recA-related gene, RAD51D/RAD51L3
    • Pittman DL, Schimenti JC (2000) Mid-gestation lethality in mice deficient for the recA-related gene, RAD51D/RAD51L3. Genesis 26: 167-173
    • (2000) Genesis , vol.26 , pp. 167-173
    • Pittman, D.L.1    Schimenti, J.C.2
  • 28
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou EP, Boon C, Redon C, Bonner WM (1999) Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 146: 905-916
    • (1999) J Cell Biol , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 29
    • 0034596020 scopus 로고    scopus 로고
    • Evidence for simultaneous protein interactions between human Rad51 paralogs
    • Schild D, Lio YC, Collins DW, Tsomondo T, Chen DJ (2000) Evidence for simultaneous protein interactions between human Rad51 paralogs. J Biol Chem 275: 16443-16449
    • (2000) J Biol Chem , vol.275 , pp. 16443-16449
    • Schild, D.1    Lio, Y.C.2    Collins, D.W.3    Tsomondo, T.4    Chen, D.J.5
  • 30
    • 0033501050 scopus 로고    scopus 로고
    • Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can be partially rescued in a p53(-/-) background
    • Shu ZG, Smith S, Wang LJ, Rice MC, Kmiec EB (1999) Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can be partially rescued in a p53(-/-) background. Mol Cell Biol 19: 8686-8693
    • (1999) Mol Cell Biol , vol.19 , pp. 8686-8693
    • Shu, Z.G.1    Smith, S.2    Wang, L.J.3    Rice, M.C.4    Kmiec, E.B.5
  • 31
    • 0035893241 scopus 로고    scopus 로고
    • Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange
    • Sigurdsson S, Van Komen S, Bussen W, Schild D, Albala JS, Sung P (2001) Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange. Genes Dev 15: 3308-3318
    • (2001) Genes Dev , vol.15 , pp. 3308-3318
    • Sigurdsson, S.1    Van Komen, S.2    Bussen, W.3    Schild, D.4    Albala, J.S.5    Sung, P.6
  • 32
    • 1942538492 scopus 로고    scopus 로고
    • ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
    • Stiff T, O'Driscoll M, Rief N, Iwabuchi K, Lobrich M, Jeggo PA (2004) ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res 64: 2390-2396
    • (2004) Cancer Res , vol.64 , pp. 2390-2396
    • Stiff, T.1    O'Driscoll, M.2    Rief, N.3    Iwabuchi, K.4    Lobrich, M.5    Jeggo, P.A.6
  • 35
    • 0035796042 scopus 로고    scopus 로고
    • Homologous recombinational repair of DNA ensures mammalian chromosome stability
    • Thompson LH, Schild D (2001) Homologous recombinational repair of DNA ensures mammalian chromosome stability. Mutat Res 477: 131-153
    • (2001) Mutat Res , vol.477 , pp. 131-153
    • Thompson, L.H.1    Schild, D.2
  • 36
    • 0035930537 scopus 로고    scopus 로고
    • Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
    • Ward IM, Chen JJ (2001) Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. J Biol Chem 276: 47759-47762
    • (2001) J Biol Chem , vol.276 , pp. 47759-47762
    • Ward, I.M.1    Chen, J.J.2
  • 37
    • 0038143321 scopus 로고    scopus 로고
    • Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX
    • Ward IM, Minn K, Jorda KG, Chen J (2003) Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX. J Biol Chem 278: 19579-19582
    • (2003) J Biol Chem , vol.278 , pp. 19579-19582
    • Ward, I.M.1    Minn, K.2    Jorda, K.G.3    Chen, J.4
  • 39
    • 0042626553 scopus 로고    scopus 로고
    • Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast
    • Wolner B, van Komen S, Sung P, Peterson CL (2003) Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast. Mol Cell 12: 221-232
    • (2003) Mol Cell , vol.12 , pp. 221-232
    • Wolner, B.1    Van Komen, S.2    Sung, P.3    Peterson, C.L.4
  • 40
    • 3042676518 scopus 로고    scopus 로고
    • Preferential binding to branched DNA strands and strand-annealing activity of the human Rad51B, Rad51C, Rad51D and Xrcc2 protein complex
    • Yokoyama H, Sarai N, Kagawa W, Enomoto R, Shibata T, Kurumizaka H, Yokoyama S (2004) Preferential binding to branched DNA strands and strand-annealing activity of the human Rad51B, Rad51C, Rad51D and Xrcc2 protein complex. Nucleic Acids Res 32: 2556-2565
    • (2004) Nucleic Acids Res , vol.32 , pp. 2556-2565
    • Yokoyama, H.1    Sarai, N.2    Kagawa, W.3    Enomoto, R.4    Shibata, T.5    Kurumizaka, H.6    Yokoyama, S.7
  • 42
    • 0342561644 scopus 로고    scopus 로고
    • Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
    • Zhu XD, Kuster B, Mann M, Petrini JHJ, de Lange T (2000) Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nat Genet 25: 347-352
    • (2000) Nat Genet , vol.25 , pp. 347-352
    • Zhu, X.D.1    Kuster, B.2    Mann, M.3    Petrini, J.H.J.4    De Lange, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.